Authors' Reports
Zeeshan Feroz
describes for SIIC the most significant aspects of his article
describe para SIIC los aspectos relevantes de su artículo


Results of the study suggest that animals of group received amiodarone-glibenclamide-captopril-oxcarbazepine combination revealed comparatively more toxic effects than two other combinations. However, more studies on large number of animals and human beings are required to justify the use of multiple drug administration, since trial in man is the only way of establishing drug interactions.

The article was published by
El artículo fue publicado por
Latin American Journal of Pharmacy
Volume / Volumen: 30
Number / Número: 2
First and last pages / Páginas inicial-final: 229-236
Year / Año: 2011
Month / Mes: march

This journal, which is covered by SIIC Data Bases,
is part of the bibliographic collections of the Biblioteca Biomédica (BB) SIIC.
Esta revista, clasificada por SIIC Data Bases,
integra el acervo bibliográfico de la Biblioteca Biomédica (BB) SIIC.

Principal institution where the research took place
Institución principal de la investigación
Department of Pharmacology, University of Karachi, Karachi, Pakistan

Author's Report

Crónica del Autor

Bibliographic references
Referencias bibliográficas

1. Feroz Z, Khan R, Afroz S. Adverse Effects of Anti-Epileptic, Anti-Hypertensive, Anti-Diabetic and Anti-Arrhythmic Drugs on Hematological and Hepatic Parameters. Lat Am J Pharm 30(2):229-236, 2011.
2. Herlong. Approach to the patient with abnormal liver enzymes. Hosp Pract 29(11):32-38, 1994.
3. Koh Y, Moideen FB, Li SC. Drug-related problems in hospitalized patients on polypharmacy: the influence of age and gender. Ther Clin Risk Manag 1(1):39-48, 2005.
4. McMillan R. Hemorrhagic disorders: Abnormalities of platelet and vascular function. En: L. Goldman & D. Ausiello (Ed.), W. B. Saunders Company, Philadelphia. pp. 1289-1301, 2007.
5. Mendez M, Parera V, Salamanca RED, Batlle A. Amiodarone is a pharmacologically safe drug for porphyrias. Gen Pharmacol 32(2):259-263, 1999.
6. Pratt DS, MM Kaplan. Evaluation of abnormal liver-enzyme results in asymptomatic patients. New Eng J Med 342(17):1266-1271, 2000.
7. Renner EL, Dallenbach A. Increased liver enzymes: what should be done? Ther Umsch 49(5):281-286, 1992.
8. Richer M, Robert S. Fatal hepatotoxicity following oral administration of amiodarone. Ann Pharmacother 29(6):582-586, 1995.
9. Schafer AI. Thrombocytosis. New Eng J Med 350:1211-1219, 2004.
10. Usdin YS, Sausville EA, Hutchins JB, Thomas K, Woosley RL. Amiodarone-induced lymphocyte toxicity and mitochondrial function. J Cardiovasc Pharm 28(1):94-100, 1996.
11. Weinberger I, Rotenberg Z, Fuchs J, Ben-Sasson E, Agmon J. Amiodarone induced thrombocytopenia. Arch Intern Med 147(4):735-736, 1987.

Other articles written by the author Zeeshan Feroz
Otros artículos de Zeeshan Feroz

1. Cumulative toxicities on lipid Profile and glucose following administration of anti-epileptic, anti-hypertensive, anti-diabetic and anti-arrhythmic drugs. Pak. J. Pharm. Sci. Vol. 24 (1), Jan (2011) 47-51.
2. Adverse effects of cumulative administration of anti-epileptic, anti-hypertensive, anti-diabetic and anti-arrhythmic drugs on renal and cardiac parameters. Int. J Med. Res. 1 (1), Aug (2010) 39-47.

3. Evaluation of hypoglycemic effect of Cassia italica. J. basic appl. Sci. 7 (1), Jan (2011) 61-64.
4. Effect of Berberis aristata on lipid profile and coagulation parameters. Afr. J. Pharm. Pharmacol. 5 (7), July (2011) 943-947.
5. Effect of multiple drug administration on gross toxicities and electrolytes. Pak. J. Pharmacol. 26 (2), July (2009) 33-39.

SIIC System of Assisted Editing (SSEA)
/ Sistema SIIC de Edición Asistida (SSEA)

Zeeshan Feroz was invited by SIIC on
Zeeshan Feroz fue invitado por SIIC el
2011, june 16
  The author's report was accepted on
La crónica del autor fue aprobada el
2017, june 7
The author's report was accepted on
La crónica del autor fue aprobada el
2017, june 7
Published in siicsalud
Publicado en siicsalud
2017, september 5

The article is strictly related to the following sections of siicsalud
El artículo se relaciona estrictamente con las siguientes secciones de siicsalud

/ Farmacología
Pharmaceutical Medicine
/ Medicina Farmacéutica

and secondarily related to the following sections

y secundariamente con las siguientes secciones




Information about the full text
Acerca del trabajo completo

Adverse Effects of Anti-Epileptic, Anti-Hypertensive, Anti-Diabetic and Anti-Arrhythmic Drugs on Hematological and Hepatic Parameters

Author / Autor
Rafeeq Alam Khan1

1 Professor, College Of Medicine; Department Of Basic Medical Sciences; King Saud Bin Abdulaziz University Of Health Sciences; King Abdulaziz Medical City Jeddah Kingdom Of Saudi Arabia, Professor

Access to the original source
Latin American Journal of Pharmacy

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