Abstract
The study of chromosomal abnormalities by karyotype is of fundamental importance at the diagnosis of chronic myeloid leukemia. After treatment, molecular techniques like fluorescent in situ hybridization (FISH) as well as RT-PCR are also extremely important to monitor residual disease. Today different types of probes for BCR/ABL are available and their applicability is here discussed.

Key words
Philadelphia chromosome, FISH

Bibliografía del artículo

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