Abstract
The aim of the study was to determine if the cell-mediated immune response may have any prognostic signification in cancer of the colon and rectum. Material and Methods: A series of 77 patients operated for cancer of the colon and rectum in the same hospital and with identical criteria during two years are analyzed prospectively for a ten year follow up. Dukes stages were: A = 4, B = 19, C = 49 y D = 5. Survival according stages was: 4/4 in stage A, 7/19 (36.8%) B, 8/49 (16.32%) C y 0/5 (0%) D. Before operation and 48 h. thereafter and at 30 days cell-mediated immune reactivity skin test was done trough a multiple antigen compouind -Multitrst-R. Results: Comparison of preoperative numeric results according staging with a control group demonstrates, a significative diference for patients stage B and very significative for stage considering patients alive and death at ten years. Conclusion: Cell-mediated immune reactivity skin test measured preoperatively may represent a prognostic factor y cancer of the colon and rectum for stages B and C.

Key words
Cancer, colon, rectum, survival

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