Resumen
Neste trabalho são descritos os aspectos tomográficos dos linfomas pulmonares e feita correlação com os achados anatomopatológicos. Com este objetivo, foram revisadas as tomografias computadorizadas do tórax e dados histopatológicos de dezoito pacientes com diagnóstico confirmado de linfoma não-Hodgkin ou de doença de Hodgkin. Os resultados obtidos foram confrontados com os descritos na literatura. Os achados radiológicos mais comumente vistos neste estudo foram as consolidações parenquimatosas, localizadas, com broncogramas aéreos de permeio (n = 14). Em menor freqüência, foram encontrados múltiplos nódulos parenquimatosos (n = 8), espessamento peribroncovascular (n = 6), opacidades em vidro fosco (n = 3), e massa escavada (n = 1). Na correlação com a anatomia patológica, as consolidações corresponderam a preenchimento alveolar por células neoplásicas, o espessamento peribroncovascular se deveu a infiltração das bainhas peribroncovasculares por células linfomatosas e a atenuação em vidro fosco se associou com infiltração dos septos alveolares por tais células.
Palabras clave
Linfomas pulmonares, tomografia computadorizada de alta resolução, anatomopatologia
Clasificación en siicsalud
Artículos originales> Expertos de Iberoamérica>
página www.siicsalud.com/des/des039/04824009.htm
Especialidades
Principal: Diagnóstico por Imágenes
Relacionadas: Hematología, Medicina Interna, Anatomía Patológica, Neumonología
Patrocinio y reconocimiento
Artículo completo
(castellano)
Extensión:
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PULMONARY LYMPHOMAS. HIGH-RESOLUTION COMPUTED TOMOGRAPHY-ANATOMOPATHOLOGICAL CORRELATION
Abstract
This paper describes the tomographic and anatomopathologic appearances of pulmonary lymphomas. We studied the thoracic computed tomographies and histopathological dates of eighteen patients biopsy-proven non-Hodgkin's and Hodgkin's disease. The most common radiologic findings in this series are the alveolar opacities with an air bronchogram (n = 14). Other manifestations include multiple pulmonary nodules (n = 8), thickening of bronchovascular bundles (n = 6), foci of ground-glass attenuation (n = 3), and cavitated mass (n = 1). The present series confirms the available literature about the radiographic appearence of the disease. The pathological correspondence of the areas of airspace consolidation was alveolar filling by neoplastic cells, the thickening of the bronchovascular bundles was secondary to infiltrates of lymphomatous cells and the areas of ground-glass attenuation corresponded to alveolar septal infiltration by these cells.
Key words
Pulmonary lymphomas, high-resolution computed tomography, pathology
Bibliografía del artículo
- Lee KS, Kim Y, Primack SL. Imaging of pulmonary lymphomas. AJR 1997; 168: 339-345.
- Au V, Leung AN. Radiologic manifestations of lymphoma in the thorax. AJR 1997; 168: 93-98.
- Hwang JH, Kim TS, Han J, Lee KS. Primary lymphoma of the lung simulating bronchiolitis: radiologic findings. AJR 1998; 170: 220-221.
- Thurlbeck WM, Miller RR, Müller NL, Rose III S. Difuse diseases of the lung. A team approach. Mosby-Year Book. Philadelphia 1991.
- Lewis ER, Caskey CI, Fishman EK. Lymphoma of the lungs: CT findings in 31 patients. AJR 1991; 156:711-714.
- Turner RR, Colby TV, Doggett RS. Well-differentiated lymphocytic lymphoma: a study of 47 patients with primary manifestation in the lung. Cancer 1984; 54: 2088-2096.
- Cordier JF, Chailleux E, Lauque D, et al. Primary pulmonary lymphomas: a clinical study of 70 cases in nonimmunocompromised patients. Chest 1993; 103: 201-208.
- Honda O, Johkoh T, Ichikado K et al. Differential Diagnosis of Lymphocytic Pneumonia and Malignant Lymphoma on High Resolution CT. AJR 1999; 173: 71-74.
- Gollub MJ, Castellino RA. Diffuse endobronchial non-Hodgkin lymphoma: CT demonstration. AJR 1995; 164: 1093-1094.
- Eisner MD, Kaplan LD, Herndier B, Stulbarg MS. The pulmonary manifestations of AIDS-Related non-Hodgkin lymphoma. Chest 1996; 110: 729-736.
- Stolberg HO, Patt NL, Mac Ewen KF, Warwick OH, Brown TC. Hodgkin's Diseases of the Lung: Roentgenologic-Pathologic Correlation. Radiology 1964; 92: 96-115. Carignan S, Staples CA, Müller NL. Intrathoracic lymphoproliferative disorders in the immunocompromised patient: CT findings. Radiology 1995; 197: 53-58.
- Balikian J, Herman PG. Non-Hodgkin Lymphoma of the Lungs. Radiology 1979; 132: 569-576.
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