COMPARISON OF A NEEDLE-FREE-HIGH-PRESSURE INJECTION SYSTEM WITH NEEDLE-TIPPED INJECTION OF INTRACAVERNOSAL ALPROSTADIL FOR ERECTILE DYSFUNCTION

Abstract
We compared the pain of injection, and efficacy of response of penile alprostadil delivery by needle injection, to transdermal needle free jet injection in patients with erectile dysfunction. Eight patients received both injection methods in a randomised order with a one week interval between injections. The transdermal jet injector was significantly less efficacious than drug delivery by needle. The jet injector also produced significantly more pain and bruising. We conclude that, as used here, the high-pressure needle free injector is not a viable alternative to direct intracavernosal injection for the delivery of alprostadil for erectile dysfunction.

Key words
Intracavernosal injection, erectile dysfunction, alprostadil

Bibliografía del artículo

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