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ASSOCIAÇAO ENTRE FUNÇAO ENDOTELIAL E BALANÇO AUTONOMICO (Y MODULACION AUTONOMICA) EM INDIVIDUOS SAUDAVEIS
(especial para SIIC © Derechos reservados)
A associação da função endotelial com o balanço autonômico em sujeitos saudáveis, ativos e muito ativos, demonstra a ação (demuestra la acción) simultânea entre respostas biológicas das células endoteliais e estímulos neurohumorais do sistema nervoso autônomo, ambos visando o adequado controle cardiovascular (ambos con vistas al adecuado control cardiovascular).
Autor:
Alexandra Braun
Columnista Experta de SIIC

Institución:
Hospital Universitário de Santa Maria (HUSM)


Artículos publicados por Alexandra Braun
Coautores
Antonio Marcos Vargas Da Silva* Thiago Dipp** Rodrigo Della Méa Plentz*** 
Fisioterapeuta, Universidade Federal de Santa Maria, Santa Maria, Brasil*
Fisioterapeuta, Faculdade de Desenvolvimento do Rio Grande do Sul (FADERGS), Porto Alegre, Brasil**
Fisioterapeuta, Universidade Federal de Ciências da Saúde de Porto Alegre (UFCSPA), Porto Alegre, Brasil***
Recepción del artículo
1 de Agosto, 2016
Aprobación
9 de Noviembre, 2016
Primera edición
15 de Marzo, 2017
Segunda edición, ampliada y corregida
12 de Mayo, 2017
doi: http://dx.doi.org/10.21840/siic/152679

Resumen
Objetivo: Avaliar a associação da função endotelial com o balanço autonômico, variáveis antropométricas e bioquímicas em indivíduos saudáveis (Evaluar la asociación de la función endotelial con el equilibrio autónomo, variables antropométricas y bioquímicas en sujetos sanos). Metodologia: Estudo transversal com 35 voluntários normotensos, ativos e muito ativos, de ambos os sexos (27.5 ± 5.8 anos de idade). O balanço autonômico foi estimado pela medida da variabilidade da frequência cardíaca, com o Polar RS800CX, por 20 minutos (10 minutos em ventilação espontânea/10 minutos com ventilação controlada). O sinal foi analisado pelo (La señal se analizó con el) software Kubios Heart Rate Variability. A frequência respiratória foi fixada em um (La frecuencia respiratoria se estableció con un) metrônomo ajustado a 12 irpm. A função endotelial foi avaliada por ultrassonografia da artéria braquial e estimada pela dilatação mediada pelo fluxo. Resultados: Houve correlação negativa entre a dilatação mediada pelo fluxo e a relação (Hubo una correlación negativa entre la dilatación mediada por el flujo y la relación) LF/HF (r = -0.43; p = 0.011), componente de baixa frequência (componente de baja frecuencia) (LF; r = -0.41; p = 0.016), índice de massa corporal (r = -0.43; p = 0.01) e peso (r = -0.39; p = 0.02). A dilatação mediada pelo fluxo esteve associada com o componente de alta frequência (HF; r = 0.41; p = 0.015). Não houve associação da dilatação mediada pelo fluxo ou de componentes do balanço autonômico (hubo una asociación de la dilatación mediada por flujo o de los componentes del equilibrio autonómico) com colesterol total, glicemia e triglicerídeos. Conclusão: A associação da função endotelial com o balanço autonômico em sujeitos saudáveis, ativos e muito ativos, demonstra a ação simultânea entre respostas biológicas das células endoteliais e estímulos neurohumorais do sistema nervoso autônomo, ambos visando o adequado controle cardiovascular (ambos con vistas al adecuado control cardiovascular).

Palabras clave
endotélio vascular, endotelio vascular, sistema nervoso autônomo, frequência cardíaca, atividade física, actividad física, sistema nervioso autónomo, frecuencia cardíaca, actividad motora


Artículo completo

(castellano)
Extensión:  +/-6.61 páginas impresas en papel A4
Exclusivo para suscriptores/assinantes

Abstract
Objective: To evaluate the association of endothelial function with the autonomic balance, anthropometric and biochemical variables in healthy subjects. Methods: Cross-sectional study with 35 normotensive volunteers, active and very active in both sexes (27.5 ± 5.8 years old). The autonomic balance was estimated by measuring the heart rate variability, with the Polar RS800CX, for 20 minutes (10 minutes in spontaneous ventilation/10 minutes with controlled ventilation). The signal was analyzed by Kubios Heart Rate Variability Software. The respiratory rate was fixed at a metronome set at 12 breaths/min. Endothelial function was assessed by ultrasound of the brachial artery and estimated by flow-mediated dilation. Results: There was a negative correlation between flow-mediated dilation and LF/HF ratio (r = -0.43; p = 0.011), low frequency component (LF; r = -0.41; p = 0.016), body mass index (r = -0.43; p = 0.01) and weight (r = -0.39; p = 0.02). Flow-mediated dilation was associated with the high-frequency component (HF, r = 0.41; p = 0.015). There was no association of flow-mediated dilation or components of the autonomic balance with total cholesterol, blood glucose and triglycerides. Conclusion: The association of endothelial function with the autonomic balance in healthy, active and very active, it shows the simultaneous action between biological responses of endothelial cells and neuro-humoral stimuli system nervous autonomic, both through the proper cardiovascular control.

Key words
vascular endothelium, autonomic nervous system, heart rate, motor activity


Clasificación en siicsalud
Artículos originales > Expertos del Mundo >
página   www.siicsalud.com/des/expertocompleto.php/

Especialidades
Principal: CardiologíaNeurología
  Relacionadas: Educación MédicaEndocrinología y Metabolismo

Enviar correspondencia a:
Alexandra Braun, 97010-460, Rua São José, 370/503, Santa Maria, Brasil
Bibliografía del artículo
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Especialidad principal:
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