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Prediction of long-term functional outcome following different rehabilitation pathways after stroke unit discharge.
Prediction of long-term functional outcome following different rehabilitation pathways after stroke unit discharge.
Fuente:Journal of Rehabilitation Medicine
Extracto:
Planning for outpatient or home-based rehabilitation appeared to lead
more effectively to participants achieving independence over the course of 1-5
years. This may have been due to the less severe nature of these participants'
conditions, compared with those requiring inpatient rehabilitation.
Cita:J Rehabil Med 2024 May 21; 56 : jrm19458.
Autor/es:Nylén, Malin C (a) Abzhandadze, Tamar (b)
institución:(a) Institute of Neuroscience and Physiology, Rehabilitation Medicine, University of Gothenburg, Gothenburg, Sweden. malin.nylen@neuro.gu.se. (b) Institute of Neuroscience and Physiology, Rehabilitation Medicine, University of Gothenburg, Gothenburg, Sweden; Department of Occupational Therapy and Physiotherapy, Sahlgrenska University Hospital, Gothenburg, Sweden.
Real emotional experience of family members of patients transported within hospital in neurosurgical intensive care unit: A descriptive qualitative study.
Real emotional experience of family members of patients transported within hospital in neurosurgical intensive care unit: A descriptive qualitative study.
Fuente:Nursing Open
Extracto:
Family members of patients in the
NICU have complex internal experiences and multiple support needs during IHT,
reflecting the need for further standardization of the transport process. In the
future, we should improve the mode of safe IHT involving doctors, nurses and
family members of patients, ensure the safety of patient transport, meet the
social support needs of family members and improve the experience of IHT and the
medical satisfaction of family members.
Claves:experience, family members, intra‐hospital transport, neurosurgical intensive care unit, qualitative study
Cita:Nurs Open 2024 May; 11 (5) : e2151.
Autor/es:Xuan, Guo (a) Juan, Ding (b)
institución:(a) Department of Neurosurgery, Jingzhou Hospital Affiliated to Yangtze University, Jingzhou, Hubei, China. (b) Nursing Department, Jingzhou Hospital Affiliated to Yangtze University, Jingzhou, Hubei, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Extracto:
Even
though we have an array of investigations for diagnosing spinal TB, the best and
the earliest diagnosing test was imaging plus CT-guided biopsy. The confirmation
is made in the biopsy. Finding acid-fast bacteria (AFB) and NAAT tests are
additional beneficial tests to supplement the diagnosis. Hence, we can conclude
that sending for tests like AFB in pus, NAAT, and GeneXpert is a wastage of
biological samples and delays in diagnosis.
Cita:Int J Mycobacteriol 2024 Jan 1; 13 (1) : 96-99.
Autor/es:Acharya, Abhijit (a) Panda, Kirtika (b)
institución:(a) Department of Neurosurgery, IMS and SUM Hospital, Bhubaneswar, Odisha, India. (b) Department of Microbiology, IMS and SUM Hospital, Bhubaneswar, Odisha, India.
Socioeconomic Status Transition Throughout Life and Risk of Dementia.
Socioeconomic Status Transition Throughout Life and Risk of Dementia.
Fuente:Jama Network Open
Tipo de trabajo:Estudio de cohortes
Extracto:
AND RELEVANCE: This cohort study of Japanese
older adults identified that upward and downward SES transitions were associated
with risk of dementia and the length of dementia-free periods over the lifespan.
The results may be useful to understand the association between social mobility
and healthy longevity.
Cita:JAMA Netw Open 2024 May 1; 7 (5) : e2412303.
Autor/es:Sakaniwa, Ryoto (a) Shirai, Kokoro (b)
institución:(a) Public Health, Department of Social Medicine, Osaka University Graduate School of Medicine, Osaka, Japan. (b) Public Health, Department of Social Medicine, Osaka University Graduate School of Medicine, Osaka, Japan.
Conflicto:Conflict of Interest Disclosures: Dr Cador reported receiving grants from the National Institute on Aging and the UK Economic and Social Research Council. Dr Kondo reported receiving grants from the Japan Society for the Promotion of Science, the Japan Agency for Medical Research and Development, the Japan Science and Technology Agency, and the National Institutes of Health during the conduct...
of the study and receiving grants from Mitsui Fudosan Co, Ltd, Nomura Real Estate Development Co, Ltd, Pacific Consultants Co, Ltd, Nestlé Japan Ltd, Amita Holdings Co, Ltd, Yamaha Motor Co, Ltd, Totec Amenity Ltd, NTT Docomo, Inc, and NEC Corporation outside the submitted work. No other disclosures were reported.
Using 30-day modified rankin scale score to predict 90-day score in patients with intracranial hemorrhage: Derivation and validation of prediction model.
Using 30-day modified rankin scale score to predict 90-day score in patients with intracranial hemorrhage: Derivation and validation of prediction model.
Fuente:Plos One
Extracto:
This tool allows practitioners and researchers to utilize clinically available
information along with the mRS score 30 days after ICH to reliably predict the
mRS score at 90 days.
Cita:PLoS One 2024; 19 (5) : e0303757.
Autor/es:Baker, William L (a) Sharma, Mukul (b)
institución:(a) University of Connecticut School of Pharmacy, Storrs, CT, United States of America. (b) Evidence-Based Practice Center, Hartford Hospital, Hartford, CT, United States of America.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Protocol for process evaluation of ARTEMIS cluster randomised controlled trial: an intervention for management of depression and suicide among adolescents living in slums in India.
Protocol for process evaluation of ARTEMIS cluster randomised controlled trial: an intervention for management of depression and suicide among adolescents living in slums in India.
institución:(a) The George Institute for Global Health India, New Delhi, India. (b) The George Institute for Global Health India, New Delhi, India.
Conflicto:Competing interests: We declare that the George Institute for Global Health has a part-owned social enterprise, George Health Enterprises, which has commercial relationships involving digital health innovations.
Severe enterovirus infections in patients with immune-mediated inflammatory diseases receiving anti-CD20 monoclonal antibodies.
Severe enterovirus infections in patients with immune-mediated inflammatory diseases receiving anti-CD20 monoclonal antibodies.
Fuente:Rmd Open
Tipo de trabajo:Revisión
Extracto:
EV
infection should be evoked in patients with IMIDs presenting with atypical organ
involvement, especially meningoencephalitis. Anti-CD20 mAbs may lead to impaired
B-cell response against EV, although an underlying primary immunodeficiency
should systematically be discussed.
Autor/es:Martin de Frémont, Grégoire (a) Chabrolles, Hélène (b)
institución:(a) Department of Internal Medicine, National Referral Center for Rare Systemic Autoimmune Diseases, Université Paris Cité, Hôpital Cochin, Paris, France gregoire.martin-de-fremont@aphp.fr. (b) 3IHP-Infection Inflammation et Interaction Hôtes Pathogènes, Virology Department, National Reference Centre for Enteroviruses and Parechoviruses, Coordination Laboratory, CHU, Clermont-Ferrand, France.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Dimethyl fumarate treatment for unruptured intracranial aneurysms
Dimethyl fumarate treatment for unruptured intracranial aneurysms
Fuente:Bmj Open
Tipo de trabajo:Estudio aleatorizado y controlado
Extracto:
TRIAL REGISTRATION NUMBER: NCT05959759.
Claves:clinical trial, immunology, magnetic resonance imaging, vascular medicine
Cita:BMJ Open 2024 May 21; 14 (5) : e080333.
Autor/es:Huang, Jiliang (a) Zhang, Yisen (b)
institución:(a) Neurosurgery Center, Beijing Tiantan Hospital, Capital Medical University, Beijing, China. (b) Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Evaluating nomogram models for predicting survival outcomes in gastric gastrointestinal stromal tumors with SEER database analysis.
Evaluating nomogram models for predicting survival outcomes in gastric gastrointestinal stromal tumors with SEER database analysis.
Fuente:Scientific Reports
Extracto:
To enhance the clinical utility and
accessibility of our findings, we have deployed the nomogram model online,
allowing healthcare professionals and researchers worldwide to access and utilize
this predictive tool.
institución:(a) School of Electrical and Information Engineering, Zhengzhou University, Zhengzhou, 450001, China. (b) Department of Radiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
SOFA score performs worse than age for predicting mortality in patients with COVID-19.
SOFA score performs worse than age for predicting mortality in patients with COVID-19.
Fuente:Plos One
Extracto:
Our findings bring into
question the utility of SOFA score-based resource allocation in COVID-19 crisis
standards of care.
Cita:PLoS One 2024; 19 (5) : e0301013.
Autor/es:Sherak, Raphael A G (a) Sajjadi, Hoomaan (b)
institución:(a) Yale Department of Emergency Medicine, Yale School of Medicine, New Haven, CT, United States of America. (b) Department of Computer Science and Engineering, Center for Remote Health Technologies and Systems, Texas A&M Univ, College Station, TX, United States of America.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Machine learning-based model to predict delirium in patients with advanced cancer treated with palliative care: a multicenter, patient-based registry cohort.
Machine learning-based model to predict delirium in patients with advanced cancer treated with palliative care: a multicenter, patient-based registry cohort.
Fuente:Scientific Reports
Extracto:
We
believe that this model will assist healthcare providers in treating patients
with delirium and advanced cancer.
Claves:Cancer, Delirium, Feature importance, Machine learning, Palliative care
Cita:Sci Rep 2024 May 20; 14 (1) : 11503.
Autor/es:Kim, Yu Jung (a) Lee, Hayeon (b)
institución:(a) Division of Hematology and Medical Oncology, Department of Internal Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, South Korea. (b) Department of Biomedical Engineering, Kyung Hee University, 1732 Deogyeong-daero, Giheung-gu, Yongin, 17104, South Korea.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Prevalence of HIV-related stigma manifestations and their contributing factors among people living with HIV in Sweden - a nationwide study.
Prevalence of HIV-related stigma manifestations and their contributing factors among people living with HIV in Sweden - a nationwide study.
Fuente:Bmc Public Health
Extracto:
The most dominating stigma feature was anticipation of
stigma. Female gender, shorter time since HIV diagnosis, feelings of
hopelessness, non-sharing HIV status, and lack of available emotional HIV-related
support constituted potential vulnerability factors of the four HIV-related
stigma manifestations. Our findings highlight the vital necessity to support
people living with HIV to increase their resilience to stigma in its different
forms. Exploring associated factors of HIV-related stigma manifestations may give
an indication of what circumstances may increase the risk of stigma burden and
factors amenable to targeted interventions. As individual stigma-reductions
interventions cannot be performed isolated from HIV-related stigma and
discrimination in society, a key challenge is to intensify anti-stigma
interventions also on the societal level.
Claves:HIV, People living with HIV, Stigma, Sweden
Cita:BMC Public Health 2024 May 20; 24 (1) : 1360.
Autor/es:Nilsson Schönnesson, Lena (a) Dahlberg, Marie (b)
institución:(a) Department of Global Public Health, Karolinska Institutet, Stockholm, Sweden. lena.nilsson.schonnesson@ki.se. (b) Department of Learning, Informatics, Management and Ethics, Karolinska Institutet, Stockholm, Sweden.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Phenotypic and genetic analysis of children with unexplained neurodevelopmental delay and neurodevelopmental comorbidities in a Chinese cohort using trio-based whole-exome sequencing.
Phenotypic and genetic analysis of children with unexplained neurodevelopmental delay and neurodevelopmental comorbidities in a Chinese cohort using trio-based whole-exome sequencing.
Fuente:Orphanet Journal of Rare Diseases
Tipo de trabajo:Revisión
Extracto:
Trio-WES testing is recommended for patients with
unexplained NDD-NDCs that have severe-profound NDD or multiple NDCs, particularly
those with accompanying ASD and head circumference abnormality, as these
independent factors may increase the likelihood of genetic diagnosis using
trio-WES. Moreover, NDD patients with pathogenic variants in CUL4B, KCNH1 and
PLA2G6 should be aware of potential risks of developing ASD during their disease
courses.
institución:(a) Department of Children's Neuro-endocrinology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, 510120, Guangdong, China. (b) Children's Medical Center, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou Guangdong, 510120, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Causal effect of blood osteocalcin on the risk of Alzheimer's disease and the mediating role of energy metabolism.
Causal effect of blood osteocalcin on the risk of Alzheimer's disease and the mediating role of energy metabolism.
Fuente:Translational Psychiatry
Extracto:
Further
studies are warranted to elucidate the underlying physio-pathological mechanisms.
Cita:Transl Psychiatry 2024 May 20; 14 (1) : 205.
Autor/es:Guo, Xingzhi (a) Yang, Yu-Ying (b)
institución:(a) Department of Geriatric Neurology, Shaanxi Provincial People's Hospital, Xi'an, 710068, Shaanxi, China. (b) Xi'an Key Laboratory of Stem Cell and Regenerative Medicine, Institute of Medical Research, Northwestern Polytechnical University, Xi'an, 710072, Shaanxi, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Untangling the relationship between smoking and systemic sclerosis: an analysis of the EUSTAR cohort.
Untangling the relationship between smoking and systemic sclerosis: an analysis of the EUSTAR cohort.
Fuente:Rmd Open
Extracto:
Our stratified
analysis demonstrates that smoking is associated with an increased risk for
mortality in male SSc patients but not in women. Strikingly, smoking is
associated with lower prevalence of ATA positivity, in particular in women. In
both ATA-positive and ACA-positive patients, smoking is a risk factor for
mortality, skin progression and 'any organ progression'.
institución:(a) Medicine and Rheumatology Unit, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy jacopo.ciaffi@ior.it. (b) Department of Biomedical and Neuromotor Sciences (DIBINEM), Alma Mater Studiorum University of Bologna, Bologna, Italy.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Association of OPRM1 rs1799971, HTR1B rs6296 and COMT rs4680 polymorphisms with clinical phenotype among women with fibromyalgia.
Association of OPRM1 rs1799971, HTR1B rs6296 and COMT rs4680 polymorphisms with clinical phenotype among women with fibromyalgia.
Fuente:Scientific Reports
Extracto:
Potential
gene-to-gene interaction and their association with clinical phenotype in women
with FMS should be further investigated in future studies including large sample
sizes.
Claves:Fibromyalgia, Pain genes, Single nucleotide polymorphism
institución:(a) Department of Physical Therapy, Occupational Therapy, Physical Medicine and Rehabilitation, Universidad Rey Juan Carlos, Av. de Atenas S/N, 28922, Alcorcón, Madrid, Spain. cesar.fernandez@urjc.es. (b) Center for Neuroplasticity and Pain (CNAP), Department of Health Science and Technology, Faculty of Medicine, SMI, Aalborg University, Aalborg, Denmark. cesar.fernandez@urjc.es.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Appendicular lean mass and the risk of stroke and Alzheimer's disease: a mendelian randomization study.
Appendicular lean mass and the risk of stroke and Alzheimer's disease: a mendelian randomization study.
Fuente:Bmc Geriatrics
Extracto:
The two-sample MR analysis indicated that genetically predicted
ALM was negatively related to AIS and AD. And the subgroup analysis of AIS
revealed a negative causal effect of genetically predicted ALM on LAS or SVS.
Future studies are required to further investigate the underlying mechanisms.
institución:(a) Department of Geriatrics, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China. (b) Key Laboratory of Diagnosis and Treatment of Aging and Physic-chemical Injury Diseases of Zhejiang Province, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
institución:(a) Institute for Diabetes Research and Metabolic Diseases (IDM) of the Helmholtz Center Munich at the University of Tübingen, Tübingen, Germany. Theresa.ester@med.uni-tuebingen.de. (b) Department of Internal Medicine, Division of Endocrinology, Diabetology and Nephrology, Eberhard Karls University Tübingen, Tübingen, Germany. Theresa.ester@med.uni-tuebingen.de.
Conflicto:GR is a co-founder and shareholder and works for Neuroelectrics, a company developing medical devices for NIBS. RS works for Neuroelectrics. Outside of the current work, MH reports research grants from Boehringer Ingelheim and Sanofi to the University Hospital of Tübingen, participation in advisory board for Boehringer Ingelheim, Sanofi and Amryt, and lecture fees from Amryt, Bayer, Sanofi, Eli Lilly,...
, Novartis, Novo Nordisk and Boehringer Ingelheim. TEN, KB, RV, CD, ALB, CP, HP and SK report no conflict of interest.
Reliability and validity of the modified shuttle test-paeds to measure cardiorespiratory fitness in children.
Reliability and validity of the modified shuttle test-paeds to measure cardiorespiratory fitness in children.
Fuente:Bmc Pediatrics
Extracto:
Paeds
appears to be a reliable and valid tool for estimating cardiorespiratory fitness
in typically developing children aged 6-12 years and has the advantages of being
shorter, needing less space, not requiring pacing and being self-motivational.
More studies are needed to assess whether children reach an aerobic steady state
in three minutes and how much of the results of the Paeds test can be explained
by the agility component of the task (turning and grasping or aiming a bean bag).
For clinical use, psychometric properties should be studied in various patient
groups (e.g., ADHD, DCD, and children with intellectual disabilities).
institución:(a) University for Professionals, Breda, The Netherlands. wendyaertssen@hotmail.com. (b) University for Professionals, Breda, The Netherlands.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación