Aurelio Pio Nardozza describes for SIIC the most significant aspects of his article describe para SIIC los aspectos relevantes de su artículo REACTIVE OXYGEN SPECIES CONTROL SHP-2 DIMERIZATION AND ACTIVITY SHP-2 dimerization is stabilized by the formation of disulfide bonds and it is modulated by growth factors and by the cellular redox state. Notably, the dimeric form is less active compared to its the monomeric self-inhibited counterpart pointing to dimerization as an additional mechanism to control SHP-2 activity. The article was published by El artículo fue publicado por
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Information about the full text Acerca del trabajo completo Reactive Oxygen Species and Epidermal Growth Factor Are Antagonistic Cues Controlling SHP-2 Dimerization Author / Autor Aurelio Pio Nardozza1, Melania D'orazio2, Riccardo Trapannone3, Salvatore Corallino4, Giuseppe Filomeni5, Marco Tartaglia6, Andrea Battistoni7, Gianni Cesareni8, Luisa Castagnoli9 9, University Of Rome Tor Vergata Access to the original source Molecular and Cellular Biology Article URL: / URL del artículo: http://mcb.asm.org/ URL of Abstract: / URL del abstract: http://mcb.asm.org/search?fulltext=nardozza&submit=yes&x=0&y=0 URL of Abstract page in Medline: / URL del abstract en Medline: http://www.ncbi.nlm.nih.gov/pubmed/22411627 siic DB: / siic DB: http://www.siicsalud.com/main/distriprinrel.php |