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Vinod Gauttam
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describe para SIIC los aspectos relevantes de su artículo


Several herbal extracts and phytoconstituents, despite having excellent bioactivity in vitro demonstrate less or no in vivo actions due to their poor lipid solubility. Phospholipids vesicles for the herbal preparations may produce better bioavailability and actions than the conventional phyto molecules or botanical extracts. In present study, we scientifically validated this hypothesis. Optimized combination (OC) of herbal extracts was encapsulated in phospholipids based vesicle system; this formulation at 500 mg/kg p.o. dose had shown significant antidiabetic effects in comparison to OC at 1 000 mg/kg p.o. in experimentally-induced diabetes.

The article was published by
El artículo fue publicado por
Journal of Advanced Pharmaceutical Technology and Research
Volume / Volumen: 4
Number / Número: 2
First and last pages / Páginas inicial-final: 108-117
Year / Año: 2013
Month / Mes: april

This journal, which is covered by SIIC Data Bases,
is part of the bibliographic collections of the Biblioteca Biomédica (BB) SIIC.
Esta revista, clasificada por SIIC Data Bases,
integra el acervo bibliográfico de la Biblioteca Biomédica (BB) SIIC.

Principal institution where the research took place
Institución principal de la investigación
Indo-soviet Friendship College of Pharmacy, Moga, Punjab, India

Authors' Report

Crónica del Autor

Bibliographic references
Referencias bibliográficas

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Manach C, Scalbert A, Morand C, Remesy C, Jimenez L. Polyphenols: food sources and bioavailability. Am J Clin Nut 79:727-747, 2004.
Niu M, Lu Y, Hovgaard L, Wu W. Liposomes containing glycocholate as potential oral insulin delivery systems: preparation, in vitro characterization, and improved protection against enzymatic degradation. Int J Nanomedicine 6:1155-1167, 2011.
Rajasekaran S, Ravi K, Sivagnanam K, Subramanian S. Beneficial effects of Aloe vera leaf gel extract on lipid profile status in rats with streptozotocin diabetes. Clin and Exp Pharmacol and Phys 33:232-237, 2006.
Rao V. Modern approaches to herbal medicine. East Pharmacist 12:35-38, 2000.
Shaw JE, Sicreem RA, Zimmet PZ. Global estimates of the prevalence of diabetes for 2010 and 2030. Diabetes Res Clin Pract 87(1):4-14, 2010.
Singleton VL, Orthofer R, Lamuela-Raventos RM. Analysis of total phenols and other oxidation substrates and antioxidants by means of folin-ciocalteu reagent. Meth Enzymol 299:152-178, 1999.
Tilburt JC, Kaptchuk TJ. Herbal medicine research and global health: an ethical analysis. Bull World Health Org 86:594-599, 2008.

Other articles written by the author Vinod Gauttam
Otros artículos de Vinod Gauttam

SIIC System of Assisted Editing (SSEA)
/ Sistema SIIC de Edición Asistida (SSEA)

Vinod Gauttam was invited by SIIC on
Vinod Gauttam fue invitado por SIIC el
2013, july 26
  The authors' report was accepted on
La crónica del autor fue aprobada el
2021, march 9
The authors' report was accepted on
La crónica del autor fue aprobada el
2021, march 9
Published in siicsalud
Publicado en siicsalud
2021, june 7

The article is strictly related to the following sections of siicsalud
El artículo se relaciona estrictamente con las siguientes secciones de siicsalud

/ Diabetología
Pharmaceutical Medicine
/ Medicina Farmacéutica

and secondarily related to the following sections

y secundariamente con las siguientes secciones

Endocrinology and Metabolism
Endocrinología y Metabolismo


Information about the full text
Acerca del trabajo completo

Development of Polyherbal Antidiabetic Formulation Encapsulated in the Phospholipids Vesicle System

Author / Autor
Vinod Gauttam1, Ajudhia Nath Kalia2

2 Dr., I S F College of Pharmacy, Moga, Moga, India

Access to the original source
Journal of Advanced Pharmaceutical Technology and Research

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