Crónicas de autores

Nora Morcillo *

Autora invitada por SIIC


SENSIBLIDIDAD IN VITRO DE MDR-TB A AGENTES ANTIMICROBIANOS EMPLEANDO UN MICROMETODO COLORIMETRICO (M-MTT)

El ensayo M-MTT podría ser utilizado en laboratorios clínicos como alternativa simple, rápida y económica para evaluar la sensibilidad de aislamientos MDR-TB a varias drogas alternativas y de segunda línea, a fin de que los resultados obtenidos sean utilizados para orientar futuras conductas terapéuticas.

*Nora Morcillo
describe para SIIC los aspectos relevantes de su trabajo
A MICROPLATE INDICATOR-BASED METHOD FOR DETERMINING THE SUSCEPTIBILITY OF MULTIDRUG-RESISTANT MYCOBACTERIUM TUBERCULOSIS TO ANTIMICROBIAL AGENTS
International Journal of Tuberculosis and Lung Disease,
8(2):253-259 Feb, 2004

Esta revista, clasificada por SIIC Data Bases, integra el acervo bibliográfico
de la Biblioteca Biomédica (BB) SIIC.

Institución principal de la investigación
*Hospital Dr. Antonio Cetrángolo, Vicente López, Argentina, Vicente López, Argentina
Imprimir nota
Referencias bibliográficas
1. Yajko D, Madej J, Lancaster M V, Sanders C A, Cawton V L, Gee B, Babst A, Keith Hadley W. Colorimetric method for determining MICs of antimicrobial agents for Mycobacterium tuberculosis. J Clin Microbiol 1995; 33: 2324-23272. Thom S M, Horobin RW, Seidler E, Barrer M R. Factors affecting the selection and use of tetrazolium salts as cytochemical indicators of microbial viability and activity. J Appl Bacteriol 1993; 74: 433-443.3. Collins L A, Franzblau S G. Microplate alamar blue assay versus BACTEC460 System for high-throughput screening of compounds against Mycobacterim tuberculosis and M. avium. Int J Tuberc Lung Dis 1997; 41: 1004-1009.4. Mshana R N, Tadesse G, Abate G, Miorner H. Use of 3-(4,5-dimetylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide for rapid detection of rifampin-resistant Mycobacterium tuberculosis. J Clin Microbiol 1998; 36: 1214-1219.5. Abate G, Mshana R N, Miorner H. Evaluation of colorimetric assay based on 3-(4,5-dimetylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) for rapid detection of rifampicin resistance in Mycobacterium tuberculosis. Int J Tuberc lung Dis 1998; 2: 1011-1016.6. Heifets L B. Conventional methods for antimicrobial susceptibility testing of M. tuberculosis. In, Bastian I., Portaels F. Multidrug-resistant tuberculosis. Kluwer Academic Publishers. 2001. London, United Kingdom. Chapter 8, pp: 135-1367. McNeil B J, Hanley J A. Statistical approaches to the analysis of receiver operating characteristic (ROC) curves. Med Decis Making 1984; 4: 137-1508. United Nations University (UNU) and Latin American and the Caribbean Network of Tuberculosis (RELACTB). New technologies for diagnosis and drug-susceptibility testing of M. tuberculosis for developing countries. 1998. Institute of National Laboratories of Health (INLASA), October 13th to 31st, La Paz, Bolivia, pp: 24-329. Toman K. Sensitivity, specificity and predictive values of diagnostic tests. Bull Int Union Tuberc 1981; 56: 18-30.10. Palomino J C, Martin A, Camacho M, Guerra H, Swings J, Portaels F. Resarzurin microtiter assay plate: simple and inexpensive method for detection of drug resistance in Mycobacterium tuberculosis. Antimicr Agents Chemother 2002; 46: 2720-2722.


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