Marina C. Costa *

Autora invitada por SIIC

DETECÇÃO DOS POLIMORFISMOS DO GENE DA DHPS DE PNEUMOCYSTIS JIROVECII EM DOENTES COM PNEUMOCISTOSE (PPC)

*Marina C. Costa
describe para SIIC los aspectos relevantes de su trabajo
DETECTION OF PNEUMOCYSTIS JIROVECII DIHIDROPTEROATE SYNTHASE POLYMORPHISMS IN PATIENTS WITH PNEUMOCYSTIS PNEUMONIA
Institución principal de la investigación
*Unidad de Parasitología y Microbiología Médica, Instituto de Higiene y Medicina Tropical, Lisboa, Portugal
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Referencias bibliográficas
1. Matos O, Lee CH, Jin S, Li B, Costa MC, Goncalves L, Antunes F. Pneumocystis jiroveci in Portuguese immunocompromised patients: association of specific ITS genotypes with treatment failure, bad clinical outcome and childhood. Infect Genet Evol 2003; 3(4):281-5.
2. Costa MC, Helweg-Larsen J, Lundgren B, Antunes F, Matos O. Mutations in the dihydropteroate synthase gene of Pneumocystis jirovecii isolates from Portuguese patients with Pneumocystis pneumonia. Int J Antimicrob Agents 2003; 22(5):516-20.
3. Costa MC, Helweg-Larsen J, Antunes F, Lungren B, Diogo J, Matos O. PCR-RFLP analysis of the DHPS gene for the study of resistance of Pneumocystis carinii to sulpha drugs in patients with co-infection PCP/HIV. J Eukaryot Microbiol 2001; Suppl:148S-149S.
4. Icenhour CR, Rebholz SL, Collins MS, Cushion MT. Widespread occurrence of Pneumocystis carinii in commercial rat colonies detected using targeted PCR and oral swabs. J Clin Microbiol 2001; 39(10):3437-41.

Otros artículos de Marina C. Costa

Matos O, Lundgren B, Aguiar P, Costa M, Antunes F. Comparison of four methods of extraction of Pneumocystis carinii from pulmonary specimens and serum. Journal of Eukaryotic Microbiology 1999; 46:102S-103S.

Costa MC, Helweg-Larsen J, Antunes F, Lundgren B, Diogo J, Matos O. PCR-RFLP analysis of DHPS gene for the study of resistance of Pneumocystis carinii to sulpha drugs in patients with co-infection PCP/HIV. Journal of Eukaryotic Microbiology 2001; Suppl:148S-149S.

Matos O, Costa MC, Lundgren B, Caldeira L, Aguiar P, Antunes F. Effect of oral washes on the diagnosis of Pneumocystis carinii pneumonia with a low parasite burden and on detection of organisms in subclinical infections. European Journal of Clinical Microbiology & Infectious Diseases 2001; 20:573-575.

Costa MC, Helweg-Larsen J, Lungren B, Antunes F, Matos O. Mutations in the dihydropteroate synthase gene of Pneumocystis jiroveci isolates from Portuguese patients with Pneumocystis Pneumonia. International Journal of Antimicrobial Agents 2003; 22(5):516-520.

Costa MC, Gaspar J, Ribeiro C, Antunes F, Matos O. Dihydropteroate synthase (DHPS) genotyping by PCR-RFLP analysis of Pneumocystis jiroveci repeated isolates from HIV-infected patients. Journal of Eukaryotic Microbiology 2003; 50 Suppl:607-608.

Matos O, Lee CH, Jin S, Li B, Costa MC, Gonçalves L, Antunes F. Pneumocystis jiroveci in Portuguese immunocompromised patients: association of specific ITS genotypes with treatment failure, bad clinical outcome and childhood. Journal of Infection, Genetics and Evolution 2003; 3(4):281-285.

Matos O, Costa MC, Correia I, Monteiro P, Monteiro M, Soares J, Vieira JR, Bonnet M, Antunes F. Pneumocystis jiroveci carriage in Portuguese immunocompetent patients. Journal of Eukaryotic Microbiology 2003; 50 Suppl:647-648.

Costa MC, Gaspar J, Mansinho K, Esteves F, Antunes F, Matos O. Detection of Pneumocystis jirovecii dihydropteroate synthase polymorphisms in patients with Pneumocystis pneumonia. Scandinavian Journal of Infectious Diseases 37:766-771.

Para comunicarse con Marina C. Costa mencionar a SIIC como referencia:
mcosta@ihmt.unl.pt

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Acerca del trabajo completo

DETECÇÃO DOS POLIMORFISMOS DO GENE DA DHPS DE PNEUMOCYSTIS JIROVECII EM DOENTES COM PNEUMOCISTOSE (PPC)

Título original en castellano
DETECÇÃO DOS POLIMORFISMOS DO GENE DA DHPS DE PNEUMOCYSTIS JIROVECII EM DOENTES COM PNEUMOCISTOSE (PPC)

Autor
Marina C. Costa¹, Jorge Gaspar², Kamal Mansinho³, Francisco Esteves⁴, Francisco Antunes⁵, Olga Matos⁶
1 Bióloga, Unidade de Protozoários Oportunistas/VIH e Outras Protozooses, Unidade de Parasitologia, Doutoranda
2 Departamento de Genética, Faculdade de Ciências Médicas, Universidade Nova
3 Serviço de Doenças Infecciosas, Hospital Egas Moniz
4 Unidade de Protozoários Oportunistas/VIH e Outras Protozooses, Unidade de Parasitologia
5 Unidade de Protozoários Oportunistas/VIH e Outras Protozooses, Unidade de Parasitologia
6 Unidade de Protozoários Oportunistas/VIH e Outras Protozooses, Unidade de Parasitologia

Acceso a la fuente original
Scandinavian Journal of Infectious Diseases
http://www.tandf.co.uk/journals/titles/00365548.asp