Olvidé mi contraseña
Asóciese a SIIC en Internet para utilizar sin límites tanto siicsalud como la totalidad de los servicios bibliográficos de la institución.
SIIC selecciona textos completos de calidad y de reciente publicación en fuentes prestigiosas del mundo
indizadas por SIIC Data Bases, capturadas en las mismas colecciones o en diversas bases especializadas.
La creciente cantidad de artículos con Acceso Abierto (Open
Access) amplía la oferta de lectura pero a su vez también, entre
tanta abundancia, complica al lector en su encuentro con los estudios
fundamentales. Para facilitarlo, profesionales biomédicos de SIIC
consultan diariamente una profusa cantidad de documentos que nutrirán
Textos completos autorizados (TCA).
Las citas de la sección TCA enlazan de manera legal, autorizada y
gratuita con los textos completos (full text) publicados en
los sitios oficiales de sus respectivas fuentes.
SIIC creó, produjo y opera con exclusividad el software TCA para la
interpretación de los diversos campos documentales que integran la
estructura de un estudio: especialidad, modalidad del estudio,
fuente, fechas de publicación y selección, definición de la fuente,
limitaciones de consulta, resumen en castellano, etc.
Si bien la mayoría de los textos seleccionados corresponden a
artículos originales, revisiones y guías, los lectores también
encontrarán comentarios, entrevistas, notas periodísticas, cartas a
autores u otros textos precursores de debates o aclaratorios.
Sociedad Iberoamericana de Información Científica (SIIC) selects
complete quality-full texts which have been recently published in
renowned sources worldwide and are indexed by SIIC Data
Bases.
The increasing number of Open Access articles widens the reading offer
but, also, such myriad complicates the readers search of fundamental
articles. To facilitate this, SIIC biomedical professionals daily
consult a profuse amount of documents that will feed
Authorized Full Texts (TCA, Spanish acronym).
The citations of the AFT section link legally, authorized and free of
charge with the full texts published in the official web sites of
their corresponding sources.
SIIC created, produced and handles the AFT software that deciphers
the various documentary fields that form part of the structure of a
study: specialty, study style, source, publication and selection
dates, source definition, query limitations, summary in Spanish,
etc.
While most of the selected texts belong to original articles,
reviews, and guidelines, readers will also find commentaries,
interviews, journalistic reports, letters to authors or other texts
that may lead to discussions or clarifications.
The impact of obstructive sleep apnea on early surgical site infections in elderly PLIF patients: a retrospective propensity score-matched analysis.
The impact of obstructive sleep apnea on early surgical site infections in elderly PLIF patients: a retrospective propensity score-matched analysis.
Fuente:Journal of Orthopaedic Surgery and Research
Tipo de trabajo:Estudio de cohortes
Extracto:
OSA
significantly increases the risk of early SSIs and prolongs hospital stays in
elderly PLIF patients. Subgroup analysis suggests that CPAP/APAP therapy may have
benefits to OSA patients, though this association requires validation through
prospective studies. These findings emphasize the importance of preoperative OSA
screening and management to improve surgical outcomes in this high-risk
population.
institución:(a) Department of Urological Surgery, People's Hospital of Yuechi County, Guang'an, 638300, Sichuan, People's Republic of China. (b) Department of Orthopaedics, Affiliated Hospital of North Sichuan Medical College, Nanchong, 637000, Sichuan, People's Republic of China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Study protocol for assessing the effectiveness, implementation fidelity and uptake of attachment & child health (ATTACH™) Online: helping children vulnerable to early adversity.
Study protocol for assessing the effectiveness, implementation fidelity and uptake of attachment & child health (ATTACH™) Online: helping children vulnerable to early adversity.
Fuente:Bmc Pediatrics
Extracto:
PROTOCOL VERSION: Version 1.
Claves:ATTACH™ Online, Child development, Effectiveness-implementation hybrid (EIH) Type II study, Normalization process theory, Parenting program, Parent–child interaction, Quasi-experimental design, Reflective function, Study protocol
Cita:BMC Pediatr 2025 Apr 9; 25 (1) : 280.
Autor/es:Letourneau, Nicole (a) Anis, Lubna (b)
institución:(a) Child Development Centre, 3, Owerko Centre at the Alberta Children's Hospital Research Institute, University of Calgary, 3rd Floor, 3820 24 Avenue NW, Calgary, AB, Canada. Nicole.letourneau@ucalgary.ca. (b) Owerko Centre at the Alberta Children's Hospital Research Institute, University of Calgary, Calgary, AB, Canada.
Conflicto:Declarations. Ethics approval and consent to participate: Ethics approval has been obtained from the Conjoint Health Research Ethics Board (CHREB; Ethics ID: REB20-0903) of the University of Calgary, and all participants will undergo a process of informed consent. The University of Calgary is the lead agency conducting the study and partner agency research sites rely on CHREB’s approval as part...
rt of their agency ethics protocols. All funding and research guidance flows from the University of Calgary and partner agencies will not have access to the study data, nor will they be involved in data analysis or data storage. The participants will be asked to provide informed consent. We have created different consent forms for the individual interviews and intervention participation to clearly indicate to parents what they are consenting to participate in (see Appendix 1 and 2). Consent for publication: Not applicable. Competing interests: The authors MH and NL are co-owners of the for-profit and not-for-profit companies engaged in delivering ATTACH™. All other authors have no competing interests to report.
Extracto:
Health systems may benefit from prescriptive strategies
to identify, diagnose, resource, and address the determinants that constitute
patient access management. Additional research is warranted to understand each
determinant.
Claves:Access to care, Ambulatory, Equity, Management, Scheduling
Cita:BMC Health Serv Res 2025 Apr 9; 25 (1) : 524.
Autor/es:Woodcock, Elizabeth (a) Profeta, Chris (b)
institución:(a) Patient Access Collaborative, Emory University Rollins School of Public Health, elizabeth@elizabethwoodcock.com. (b) Patient Access Collaborative, Emory University Rollins School of Public Health.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Kangaroo mother care among hospitalised neonates: evaluation of the validity of duration measurement methods compared to observation linked to the OMWaNA trial in Uganda.
Kangaroo mother care among hospitalised neonates: evaluation of the validity of duration measurement methods compared to observation linked to the OMWaNA trial in Uganda.
Fuente:Bmc Pediatrics
Extracto:
Healthcare worker records provide a reasonably accurate
estimate of KMC duration at the population level, supporting the integration of
KMC indicators into national health information systems to facilitate monitoring
and evaluation. The presence of a helper increases KMC duration, underscoring the
need for research to identify strategies to increase family involvement.
Claves:Kangaroo mother care, Low-birth-weight, Neonate, Prematurity, Validation
Cita:BMC Pediatr 2025 Apr 9; 25 (1) : 283.
Autor/es:Tumukunde, Victor S (a) Sekitoleko, Isaac (b)
institución:(a) Non-Communicable Disease Programme, Medical Research Council, Virus Research Institute and LSHTM Uganda Research Unit, PO Box 49, Entebbe, Uganda. Victor.tumukunde@mrcuganda.org. (b) Department of Infectious Disease Epidemiology and International Health, London School of Hygiene & Tropical Medicine, Keppel Street, WC1E 7HT, London, UK. Victor.tumukunde@mrcuganda.org.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Causal relationship between childhood obesity and osteoporosis: A STROBE two-sample Mendelian randomization study.
Causal relationship between childhood obesity and osteoporosis: A STROBE two-sample Mendelian randomization study.
Fuente:Medicine
Extracto:
Our MR study revealed a significant causal
relationship between childhood obesity and osteoporosis, indicating that
childhood obesity can reduce the incidence of osteoporosis.
Cita:Medicine (Baltimore) 2025 Jan 3; 104 (1) : e41209.
Autor/es:Zheng, Chaoshun (a) Chen, Taiqiu (b)
institución:(a) Department of Orthropedics II, Jieyang People's Hospital, Jieyang, China. (b) Department of Orthropedics II, Jieyang People's Hospital, Jieyang, China.
Conflicto:The authors have no funding and conflicts of interest to disclose.
The wide phenotypic spectrum of thiamine metabolism dysfunction syndrome 5 and its treatment.
The wide phenotypic spectrum of thiamine metabolism dysfunction syndrome 5 and its treatment.
Fuente:Orphanet Journal of Rare Diseases
Extracto:
Further studies are needed to identify
available biomarkers and establish correlations between different variants,
severity, and treatment response.
institución:(a) Postgraduate School of Pediatrics, University of Torino, Torino, Italy. (b) Department of Public Health and Pediatric Sciences, School of Medicine, University of Torino, Torino, Italy.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
BRAF V600E Mutation in Ganglioglioma: Impact on Epileptogenicity and Implications for Surgical Strategy.
BRAF V600E Mutation in Ganglioglioma: Impact on Epileptogenicity and Implications for Surgical Strategy.
Fuente:European Journal of Neurology
Tipo de trabajo:Revisión
Extracto:
BRAF V600E status in patients with ganglioglioma-associated epilepsy
is a potential biomarker to stratify the risk for seizure relapse after surgery.
BRAF V600E-positive patients might benefit from a more aggressive surgical
strategy.
institución:(a) Department of Neurosurgery, Medical University of Vienna, Vienna, Austria. (b) Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
institución:(a) Institute of Medical Science, University of Toronto, Toronto, Ontario, Canada. (b) Program in Neurosciences and Mental Health, The Hospital for Sick Children, Toronto, Ontario, Canada.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
institución:(a) Human Genetics, Faculty of Medicine, University of Augsburg, Augsburg, Germany. monika.golas@med.uni-augsburg.de. (b) Comprehensive Cancer Center Augsburg, University Medical Center Augsburg, Augsburg, Germany. monika.golas@med.uni-augsburg.de.
Conflicto:Competing interests: The authors are not aware of any conflict of interest related to this study.
The response to anti-seizure medications and the development of pharmacoresistant epilepsy in malformations of cortical development.
The response to anti-seizure medications and the development of pharmacoresistant epilepsy in malformations of cortical development.
Fuente:Bmc Medicine
Extracto:
Our findings indicate a high prevalence
of PRE that varies among different subtypes of MCD. Early appropriate selection
of ASMs, particularly SCBs, can significantly delay the time to PRE onset,
offering a promising strategy for managing this complex patient population.
Tailoring pharmacological approaches is crucial for optimizing outcomes, and
further research is warranted to optimize treatment strategies.
Claves:Malformations of cortical development, Pharmacoresistant epilepsy, Sodium channel blockers
Cita:BMC Med 2025 Apr 7; 23 (1) : 198.
Autor/es:Miao, Pu (a) Ying, Meiping (b)
institución:(a) Department of Neurology, School of Medicine, Epilepsy Center, Second Affiliated Hospital, Zhejiang University, Hangzhou, 310009, China. (b) Department of Pediatric, School of Medicine, Second Affiliated Hospital, Zhejiang University, Hangzhou, 310009, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Dietary riboflavin (vitamin B2) intake and osteoporosis in U.S. female adults: unveiling of association and exploration of potential molecular mechanisms.
Dietary riboflavin (vitamin B2) intake and osteoporosis in U.S. female adults: unveiling of association and exploration of potential molecular mechanisms.
Fuente:Nutrition Journal
Extracto:
Higher
intake of vitamin B2 is positively associated with reduced risks for femoral
osteoporosis and bone loss. Vitamin B2 may represent a modifiable lifestyle
factor for the prevention and management of osteoporosis.
Claves:Bone mineral density, Osteoporosis, Riboflavin, Vitamin B2
Cita:Nutr J 2025 Apr 7; 24 (1) : 53.
Autor/es:Yang, QianKun (a) Zhang, Li (b)
institución:(a) National & Regional United Engineering Lab of Tissue Engineering, Department of Orthopedics, Southwest Hospital, Army Medical University, Chongqing, 400038, China. (b) Department of Hematology, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Key Laboratory of Pediatrics, Children's Hospital of Chongqing Medical University, No.136 of Zhong Shan Second Road, YuZhong District, Chongqing, 400014, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Enabling new insights from old scans by repurposing clinical MRI archives for multiple sclerosis research.
Enabling new insights from old scans by repurposing clinical MRI archives for multiple sclerosis research.
Fuente:Nature Communications
Extracto:
MindGlide uniquely
enables quantitative analysis of archival single-contrast MRIs, unlocking
insights from untapped hospital datasets.
Cita:Nat Commun 2025 Apr 7; 16 (1) : 3149.
Autor/es:Goebl, Philipp (a) Wingrove, Jed (b)
institución:(a) Queen Square Multiple Sclerosis Centre, Department of Neuroinflammation, Faculty of Brain Sciences, University College London, London, UK. p.goebl@ucl.ac.uk. (b) UCL Hawkes Institute, University College London, London, UK. p.goebl@ucl.ac.uk.
Conflicto:Competing interests: D.C. is a consultant for Hoffmann-La Roche. In the last three years he has been a consultant for Biogen, has received research funding from Hoffmann-La Roche, the International Progressive MS Alliance, the MS Society, the Medical Research Council, and the National Institute for Health Research (NIHR) University College London Hospitals (UCLH) Biomedical Research Centre, and a speaker’s honorarium...
um from Novartis. He co-supervises a clinical fellowship at the National Hospital for Neurology and Neurosurgery, London, which is supported by Merck. F.B. acts as a member of the steering committee or Data Safety Monitoring Board for Biogen, Merck, ATRI/ACTC and Prothena. Consultant for Roche, Celltrion, Rewind Therapeutics, Merck, IXICO, Jansen, Combinostics. Research agreements with Merck, Biogen, GE Healthcare, Roche. Co-founder and shareholder of Queen Square Analytics LTD. O.C. is a NIHR Research Professor (RP-2017-08-ST2-004); over the last 2 years, member of independent DSMB for Novartis; she gave a teaching talk in a Merck local symposium, and contributed to an Advisory Board for Biogen; she is Deputy Editor of Neurology, for which she receives an honorarium; she has received research grant support from the MS Society of Great Britain and Northern Ireland, the NIHR UCLH Biomedical Research Centre, the Rosetree Trust, the National MS Society, and the NIHR-HTA. C.H. reports grant support from the MRC and MS Society. She has served as a consultant to Novartis, Roche, UCB and Sanofi. S.N. has received research funding from the Canadian Institutes of Health Research, the International Progressive MS Alliance, the Myelin Repair Foundation, Immunotec, and F. Hoffman LaRoche, not related to the current work; he is a consultant for Sana Biotech, has received a speaker’s honorarium from Novartis Canada, and is a part-time employee of NeuroRx Research. In the last 3 years, J.C. has received support from the Health Technology Assessment (HTA) Programme (National Institute for Health Research, NIHR), the UK MS Society, the US National MS Society and the Rosetrees Trust. He is supported in part by the NIHR University College London Hospitals (UCLH) Biomedical Research Centre, London, UK. He has been a local principal investigator for a trial in MS funded by MS Canada. A local principal investigator for commercial trials funded by: Ionis and Roche; and has taken part in advisory boards/consultancy for Biogen, Contineum Therapeutics, InnoCare, Lucid, Merck, NervGen, Novartis and Roche. G.J.M.P. is a shareholder and director of, and receives salary from, Bioxydyn Limited. He is a shareholder and director of Queen Square Analytics Limited. He is a shareholder and director of Quantitative Imaging Limited. D.C.A. is a shareholder and director of Queen Square Analytics Limited. In the past three years, A.E. has received research grants from the Medical Research Council (MRC), NHS England, Imperial College Healthcare Trust, National Institute for Health and Social Care Research (NIHR), Innovate UK, Biogen, Merck, and Roche. He has served as an advisory board member of Merck Serono and Bristol Myers Squib. He is the founder and equity stakeholder in Queen Square Analytics Limited. He serves on the editorial board of Neurology (American Academy of Neurology). The remaining authors declare no competing interests.
MRI signatures of cortical microstructure in human development align with oligodendrocyte cell-type expression.
MRI signatures of cortical microstructure in human development align with oligodendrocyte cell-type expression.
Fuente:Nature Communications
Extracto:
In our study, we show spatial
and temporal alignment of oligodendrocyte cell-type gene expression with neurite
and soma microstructural changes, suggesting that ongoing cortical myelination
processes drive adolescent cortical development.
Cita:Nat Commun 2025 Apr 7; 16 (1) : 3317.
Autor/es:Genc, Sila (a) Ball, Gareth (b)
institución:(a) Cardiff University Brain Research Imaging Centre (CUBRIC), School of Psychology, Cardiff University, Cardiff, UK. sila.genc@mcri.edu.au. (b) Developmental Imaging, Clinical Sciences, Murdoch Children's Research Institute, Parkville, VIC, Australia. sila.genc@mcri.edu.au.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Comparative Clinical and Imaging-Based Evaluation of Therapeutic Modalities in CNS Embryonal Tumours With PLAGL Amplification.
Comparative Clinical and Imaging-Based Evaluation of Therapeutic Modalities in CNS Embryonal Tumours With PLAGL Amplification.
Fuente:Neuropathology and Applied Neurobiology
Extracto:
Adjuvant therapy should be considered for
all ET, PLAGL patients: Patients with ET, PLAGL2 might benefit from intensified
chemotherapy regimens. In contrast, patients with ET, PLAGL1 showed superior
outcomes without high-dose chemotherapy or craniospinal irradiation.
Claves:PLAGL1, PLAGL2, ET, PLAGL, embryonal CNS tumour, treatment
Autor/es:Keck, Michaela-Kristina (a) Tietze, Anna (b)
institución:(a) Division of Pediatric Glioma Research, Hopp Children's Cancer Center Heidelberg (KiTZ), Heidelberg, Germany. (b) National Center for Tumor Diseases (NCT), NCT Heidelberg, A Partnership Between DKFZ and Heidelberg University Hospital, Heidelberg, Germany.
Conflicto:The corresponding authors report no potential conflict of interest. Per Nyman reports minority private shareholding (SyntheticMR AB). Laura S. Korhonen is a NOPHO (Nordic Society of Paediatric Haematology) board member. Pieter Wesseling received a travel grant from Chimerix for contributing to a session during the Annual SNO 2023 meeting in Vancouver and is chair of the cIMPACT‐NOW Steering Committee. Ingrid...
id Øra is supported by the Swedish Childhood Cancer Fund (Stockholm, Sweden). Christof M. Kramm is supported by the Deutsche Kinderkrebsstiftung (Bonn, Germany) and has received grants/contracts from Blueprint Rover and Novartis. He is also on the advisory board on glioblastoma medication (Boehringer Ingelheim), chairman of the HIT‐HGG study group, (Goettingen, Germany), executive committee member of the SIOPE DIPG Registry, Utrecht, the Netherlands, and executive committee member of the Neurooncological Working Group (Berlin, Germany). Juhana Hakumäki is president of the Finnish Radiological Society. Michal Zapotocky has received an honorarium from AstraZeneca. Where authors are identified as personnel of the IARC/WHO, the authors alone are responsible for the views expressed in this article and they do not necessarily represent the decisions, policies or views of the IARC/WHO.
Botulism in the Highlands: Understanding the High-Altitude Effect.
Botulism in the Highlands: Understanding the High-Altitude Effect.
Fuente:Journal of Epidemiology and Global Health
Extracto:
The overall goal of the article is to
focus on the geographic differences in incidence, including its propensity to
high-altitude areas, and shed light on the theories behind this propensity.
Claves:Botulism, High Altitude, Neurotoxic, Paralysis
institución:(a) Department of Pediatric Neurology, Neuroscience Center, King Fahad Specialist Hospital, Dammam, Kingdom of Saudi Arabia. Momenma@moh.gov.sa. (b) King Salman Humanitarian Aid & Relief Center, Riyadh, Saudi Arabia.
Conflicto:Declarations. Ethics Approval: Not applicable. Competing Interests: Ziad Memish is the editor-in-chief of the journal.
Psychological aspects of hippotherapy for children with severe neurological impairment: An exploratory study.
Psychological aspects of hippotherapy for children with severe neurological impairment: An exploratory study.
Fuente:Plos One
Extracto:
Our study shows that hippotherapy is a feasible and
beneficial treatment for neuropediatric patients with severe neurological
impairments. The goals of hippotherapy can be much broader than the usually
targeted physical functioning and mobility. Hippotherapy might be especially
effective in promoting fun and motivation and in addressing patients'
socioemotional needs.
Cita:PLoS One 2025; 20 (4) : e0320238.
Autor/es:Hediger, Karin (a) Lunzenfichter, Marina (b)
institución:(a) Faculty of Behavioural Sciences and Psychology, University of Lucerne, Luzern, Switzerland. (b) REHAB Basel, Clinic for Neurorehabilitation and Paraplegiology, Basel, Switzerland.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Family-based treatment at home in adolescents with eating disorders and co-occurring mental health conditions: rationale and study design of a mixed methods trial.
Family-based treatment at home in adolescents with eating disorders and co-occurring mental health conditions: rationale and study design of a mixed methods trial.
Claves:Anorexia nervosa, Eating disorders, Family-Based treatment at home, Other specified feeding or eating disorder, Psychiatric comorbidity
Cita:BMC Psychiatry 2025 Apr 8; 25 (1) : 346.
Autor/es:Schapink, Andrea A H (a) van der Velde, Jildou (b)
institución:(a) Karakter, Child and Adolescent Psychiatry, Nijmegen, The Netherlands. a.schapink@karakter.com. (b) Karakter, Child and Adolescent Psychiatry, Nijmegen, The Netherlands.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Spinal deformity after thoracotomy in children with pulmonary hydatid disease.
Spinal deformity after thoracotomy in children with pulmonary hydatid disease.
Fuente:Bmc Musculoskeletal Disorders
Tipo de trabajo:Revisión
Extracto:
Children with
pulmonary hydatid cyst disease are at high risk of developing spinal deformity
after thoracotomy, and this risk is greater in younger patients. This study
emphasises the importance of multidisciplinary approaches in the prevention and
management of spinal deformity.
institución:(a) Department of Orthopaedics and Traumatology, Faculty of Medicine, Van Yüzüncü Yıl University, Van, Turkey. sehmuzkaya@yyu.edu.tr. (b) Department of Neurosurgery, Faculty of Medicine, Van Yüzüncü Yıl University, Van, Turkey.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Posttraumatic stress, anxiety, and depression in mothers after preterm delivery and the associated psychological processes.
Posttraumatic stress, anxiety, and depression in mothers after preterm delivery and the associated psychological processes.
Fuente:Bmc Pregnancy and Childbirth
Extracto:
Our findings support the transdiagnostic
nature of psychological processes and suggest that anhedonia, brooding
rumination, and worry may be relevant targets for psychological interventions to
concurrently treat PTS, anxiety, and depression symptoms. Behavioral activation
could be an effective intervention to target these dysfunctional processes and
thus improve maternal symptoms.
institución:(a) Laboratory of Behavioral Sciences and Applied Psychology (LAPSA), Douala University, Douala, Cameroon. gc.ndjomo@gmail.com. (b) Psychology and Neuroscience of Cognition Research Unit (PsyNCog), University of Liège, Liège, Belgium. gc.ndjomo@gmail.com.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
