Conceptos Categóricos

Bioquímica

  QUALITY CONTROL AT THE ENDOPLASMIC RETICULUM TRANSLOCON
The essential Sec61 translocon brings proteins into and across the endoplasmic reticulum membrane. Little was known about how proteins blocking this channel are removed. New data reveal that the Hrd1 ubiquitin ligase degrades proteins that persistently and abnormally engage Sec61. This quality control pathway may also regulate low-density lipoprotein particle synthesis.

Eric Rubenstein
New Haven, US

  
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RESPUESTA INMUNE CONTRA MICROORGANISMOS INTRACELULARES
Nocardia brasiliensis, que pertenece al grupo microbiologico de los actinomicetos, produce en el hospedero una lesión granulomatosa crónica denominada micetoma. El estudio de la respuesta inmune en modelos murinos nos ha permitido deducir los diferentes mecanismos de patogenicidad y de respuesta inmune contra microorganismos de este grupo.

Mario César Salinas Carmona
Monterrey, México

     
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PLEURESÍA TUBERCULOSA COMO MANIFESTACIÓN DE RECONSTITUCIÓN INMUNE EN UN PACIENTE CON SIDA
El síndrome inflamatorio de reconstitución inmune (SIRI) es una complicación importante y temprana en respuesta a la implementación de la terapia antirretroviral de gran actividad. Se describe un paciente con sida que presentó pleuresía por M. tuberculosis como manifestación de SIRI, luego de 2 meses del inicio de la terapia antirretroviral.

Analía Boschi
Buenos Aires, Argentina

           
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TUBERCULOSIS DIAGNOSTICS: HURDLES AND HOPES
This review discuss various conventional and modern modalities of diagnosing tuberculosis infection and critically analyzed their potential and limitations with a few suggestions about future avenues. Apart from the technical aspects of diagnostics, the important part of this review is the motivation of researchers for putting more and more efforts in this area. For this it has been highlighted that there has been an enhanced interest and awareness about the disease and related research worldwide. This was substantiated by the enlistment of some premier funding agencies. It is suggested to the researchers to take timely advantage of the opportunities being created to help them innovate.

Vijay Nema
Pune, In

     
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HERBS USED IN NIGER-DELTA REGION OF NIGERIA TO TREAT SEXUALLY TRANSMITTED DISEASES
Sexually transmitted diseases (STDs) are one of the leading diseases in Nigeria, especially in Akwa Ibom and Rivers States in Niger Delta Region. Many people rely on Traditional Medical Practitioners (TMPs) for cure of STDs. 36 plants representing 26 families were reported by 105 TMPs to cure STDs such as gonorrhea, syphilis, urethritis and leucorrhoea.

Kola' Kayode Ajibesin
Yenagoa, Ng

  
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