Bioquímica

  MODULATION OF DOXORUBICIN–INDUCED CYTOTOXICITY AND PHOTOCHEMOPREVENTIVE EFFECTS BY A GRAPE SEED EXTRACT
Grape seeds extract, Vitis vinifera L., variety Burgund Mare might be a chemoprotective candidate in reducing the oxidative stress and the risk for UV-induced cancer and recommend its use as such or in combination with sunscreens and/or other natural products with similar or complementary properties.

Gabriela Adriana Filip
Cluj Napoca, Ro

  
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  CONCENTRATION OF SEMINAL PLASMA ZINC IN VARIOUS CLASSES OF INFERTILE MALE
The present study was designed to analyze the level of seminal zinc among different groups of infertile males and to correlate it with sperm concentration, active, sluggish and immotile fractions of seminal parameters, with an objective being to establish the role of zinc. This descriptive analytical study was carried out in the Department of Reproductive Physiology/Health, Public Health Laboratories Division, National Institute of Health, Islamabad in a 5 years period from 2002 to 2006. The result showed that seminal zinc was 702.92 ± 10.60, 598.48 ± 12.95, 617.54 ± 9.55, 542.29 ± 22.75, 710.36 ± 7.87, 712.06 ± 7.96, 789.36 ± 21.33 and 762.06 ± 8.99 in azoospermic, oligozoospermic, asthenozoospermic, oligoasthenozoospermic, teratozoospermic, normozoospermic, polyzoospermic and proven fathers group, respectively. Findings of the study showed that semen zinc was several folds higher in polyzoospermic subjects as compared to other groups, while it was found to be lower in oligozoospermic, azoospermic and oligoasthenozoospermic groups. In case of proven fathers, the levels of semen zinc varied non significantly (p > 0.05) with polyzoospermic cases. It is concluded from the results of the study that decreased concentration of seminal plasma zinc affect sperm count while increased level causes decreased sperm motility.

Muhammad Shoaib Khan
Bannu, Pk

  
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  PROPIEDADES QUIMIOPREVENTIVAS DEL MANGO Y LA MANZANA EN EL CÁNCER DE COLON
La identificación de alimentos de origen vegetal, como el mango y la manzana, así como sus constituyentes con propiedades anticancerígenas, es una alternativa posible para el control, la prevención y el tratamiento de una neoplasia frecuente como el cáncer de colon.

Maria Elena Maldonado
Medellín, Colombia

           
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DIAGNÓSTICO RETROSPECTIVO DE LA INFECCIÓN CONGÉNITA POR CITOMEGALOVIRUS
El citomegalovirus congénito permanece infradiagnosticado en ausencia de clínica neonatal. Puede manifestarse con retraso de crecimiento intrauterino, microcefalia, hipoacusia neurosensorial, coriorretinitis, retardo mental y trastorno del espectro autista. El diagnóstico de certeza sólo se puede realizar pasadas las 3 primeras semanas mediante la detección de ADN de citomegalovirus a partir de sangre del papel de filtro del cribado neonatal.

Raquel Pinillos Pisón
Zaragoza, España

           
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INFLUENCE OF SALIVARY CONTAMINATION ON DENTIN BOND STRENGTH OF ONE BOTTLE ADHESIVE SYSTEMS- INVITRO STUDY
For effective bonding the primer should infiltrate demineralized collagen web. The present study showed that salivary contamination has no significant effect on the Shear Bond Strength of one bottle system when it was blot dried, washed or retched with H3PO4. When the contaminated surface was dried completely there was a significant decrease in bond strength. The bond strengths to tooth structure of recent dentin bonding agents are less sensitive to common forms of contamination than assumed. Re etching without additional mechanical preparation is sufficient to provide or achieve the expected bond strength. Thus adhesive restorations should have sufficient bond strengths to prevent micro leakage around restoration margins and reinforce the tooth structure against forces that cause fracture. Reliable bonding systems have revolutionized the practice of adhesive dentistry though improvements in bonding techniques and systems have yet to be continued.

B. P. Suryakumari Nujella
Hyderabad, In

  
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