Conceptos Categóricos

Genética Humana

THE ROLE OF VIRUS, GENES AND TOBACCO IN ORAL CANCER
The prevalence of oral squamous cell carcinoma (OSCC) has significantly increased over decades in several countries and human papilloma virus (HPV) has been indicated as one of the underlying causes. This suggests that HPV plays a role in the early stages of carcinogenesis but is not a requisite for the maintenance and progression of malignant state. p53 is a tumor suppressor gene that checks the cell and promotes apoptosis and cell repair that can be deactivated by mutations and a viral interaction leading to cancer and individuals with particular polymorphic variant of p53 is more susceptible to HPV-induced carcinogenesis. The present study has been carried out to detect and correlate p53 polymorphism/mutation, HPV DNA in the biopsy samples of oral cancer patients who had tobacco habits.

Bidyut Chakrobarty
Visakhapatnam, In

     
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 acceso_libre_20171204.png HEMOGLOBINA FANNIN-LUBBOCK I Y II, DOS VARIANTES QUE COMPARTEN UNA MUTACIÓN
Existen dos tipos de hemoglobina Fannin-Lubbock I y II: la primera, reportada en dos familias mexicano-estadounidenses, cuatro familias independientes de origen mexicano y en una familia india, las cuales pudieron haber surgido por eventos mutacionales independientes, ya que se observaron asociadas con dos haplotipos beta diferentes, y la segunda, en individuos de origen español. En ambos casos la variante mostró inestabilidad, por lo que esta característica se atribuye a la mutación en beta119.

Bertha Ibarra Cortés
Guadalajara, México

           
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EXPRESIÓN DE MICRORNAS IMPLICADOS EN LA ANGIOGÉNESIS EN CÁNCER ENDOMETRIAL.
La diferente expresión de los micro ARN observada en el tejido tumoral podría modular los niveles de factores angiogénicos y desempeñar un papel importante en la patogenia del cáncer endometrial.

Juan Gilabert-estellés
Valencia, España

  
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A CLINICO-HEMATOLOGICAL APPRAISAL OF AGGRESSIVE PERIODONTITIS
Deducing the results of the study, we can conclude that a definite association between ABO blood groups and HLA phenotypes with periodontal diseases cannot be established. Leukocytic functional defects were found in subjects with aggressive periodontitis (AP). A statistically significant percentage of CD14+ CD16+ and CD45RA monocytes were found in AP subjects as compared to the controls.

Vineet Nair
Kolkata, In

  
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MIRROR IMAGE AGNOSIA
Patients with dementia can show specific difficulty in identifying reflected self images in spite of having proper knowledge about the mirror and other reflected objects.This is seen in patients with moderate stage dementia and correlated with right parietal atrophy. real time processing of reflected self images probably have specific data linking circuits in the right parietal lobe.

Sadanandavalli Chandra
Bangalore, In

  
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