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THE ROLE OF EOSINOPHIL CATIONIC PROTEIN IN ALLERGIC INFLAMMATION
Eosinophil cationic protein (ECP) enhances cell growth of normal human dermal fibroblasts (NHDF). CNTF, NAP-2, and NT-3 may be participating inenhancing the growth of NHDF. These findings will contribute to determination of the role of ECP in allergic inflammation.
Takamaro Sato
, Japón
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NITRIC OXIDE: A BIOMARKER FOR OXIDATIVE STRESS IN ORAL LICHEN PLANUS
Saliva plays a critical role in protection and maintenance of the health of the oral cavity and is an important body fluid. Nitric oxide is a highly reactive free radical synthesized by the enzyme nitric oxide synthase by cells such as macrophages, T cells, and natural killer cells. There is a possible correlation between nitric oxide level and oral lichen planus.
ELEVATED INTRAVITREAL IL-1BETA AND IL-10 LEVELS IN PDR
In order to determine the roles of IL-1beta and IL-10 in the vitreous of PDR, we measured IL-1beta and IL-10 concentration by ELISA. We found vitreous levels of IL-1beta and IL-10 were upregulated in PDR patients, and these two cytokines play roles in regulating the development and progression of PDR.