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La Sociedad Iberoamericana de Información Científica (SIIC)
selecciona informes completos de calidad recientemente publicados en
fuentes prestigiosas del mundo indizadas por SIIC Data
Bases.
La creciente cantidad de artículos con Acceso Abierto (Open
Access) amplía la oferta de lectura pero a su vez también, entre
tanta abundancia, complica al lector en su encuentro con los estudios
fundamentales. Para facilitarlo, profesionales biomédicos de SIIC
consultan diariamente una profusa cantidad de documentos que nutrirán
Textos completos autorizados (TCA).
Las citas de la sección TCA enlazan de manera legal, autorizada y
gratuita con los textos completos (full text) publicados en
los sitios oficiales de sus respectivas fuentes.
SIIC creó, produjo y opera con exclusividad el software TCA para la
interpretación de los diversos campos documentales que integran la
estructura de un estudio: especialidad, modalidad del estudio,
fuente, fechas de publicación y selección, definición de la fuente,
limitaciones de consulta, resumen en castellano, etc.
Si bien la mayoría de los textos seleccionados corresponden a
artículos originales, revisiones y guías, los lectores también
encontrarán comentarios, entrevistas, notas periodísticas, cartas a
autores u otros textos precursores de debates o aclaratorios.
Sociedad Iberoamericana de Información Científica (SIIC) selects
complete quality-full texts which have been recently published in
renowned sources worldwide and are indexed by SIIC Data
Bases.
The increasing number of Open Access articles widens the reading offer
but, also, such myriad complicates the readers search of fundamental
articles. To facilitate this, SIIC biomedical professionals daily
consult a profuse amount of documents that will feed
Authorized Full Texts (TCA, Spanish acronym).
The citations of the AFT section link legally, authorized and free of
charge with the full texts published in the official web sites of
their corresponding sources.
SIIC created, produced and handles the AFT software that deciphers
the various documentary fields that form part of the structure of a
study: specialty, study style, source, publication and selection
dates, source definition, query limitations, summary in Spanish,
etc.
While most of the selected texts belong to original articles,
reviews, and guidelines, readers will also find commentaries,
interviews, journalistic reports, letters to authors or other texts
that may lead to discussions or clarifications.
The impact of obesity-associated glycine deficiency on the elimination of endogenous and exogenous metabolites via the glycine conjugation pathway.
The impact of obesity-associated glycine deficiency on the elimination of endogenous and exogenous metabolites via the glycine conjugation pathway.
Fuente:Frontiers in Endocrinology
Tipo de trabajo:Estudio clínico
Extracto:
Obesity-associated
glycine deficiency impairs the human body's ability to eliminate endogenous and
exogenous metabolites/compounds via the glycine conjugation pathway. This
impairment is ameliorated when glycine supply is restored after bariatric
surgery. These findings imply that dietary glycine supplementation could treat
obesity-associated metabolic complications due to the accumulation of
intramitochondrial toxic metabolites. CLINICAL TRIAL REGISTRATION:
https://clinicaltrials.gov/study/NCT04660513, identifier NCT04660513.
Claves:acylglycine, bariatric surgery, class III obesity, glycine conjugation, glycine deficiency
institución:(a) Department of Endocrinology, Singapore General Hospital, Singapore, Singapore. (b) Children's Nutrition Research Center, Agricultural Research Service, U.S. Department of Agriculture, and Department of Pediatrics, Baylor College of Medicine, Houston, TX, United States.
Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
institución:(a) Department of Endocrinology, China Resources and WISCO General Hospital, Wuhan, China. (b) Department of Cardiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Incidence of chemotherapy-related cardiac dysfunction in cancer patients.
Incidence of chemotherapy-related cardiac dysfunction in cancer patients.
Fuente:Clinical Cardiology
Tipo de trabajo:Metanálisis
Extracto:
Our meta-analysis unveiled a
definitive overall incidence rate of chemotherapy-related cardiac dysfunction in
cancer patients. In addition, it was found that the risk of developing this
condition escalates within the initial 6 months postchemotherapy, subsequently
tapering off to become statistically insignificant after a duration of 6 years.
Claves:cancer, cardiac dysfunction, chemotherapy
Cita:Clin Cardiol 2024 Apr; 47 (4) : e24269.
Autor/es:Deng, Hai-Wei (a) Fan, Rui (b)
institución:(a) Department of Cardiology, The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, China. (b) Key Laboratory on Assisted Circulation Ministry of Health, Guangzhou, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Causal relationship of genetically predicted particulate matter 2.5 level with Alzheimer's disease and the mediating effect of dehydroepiandrosterone sulphate.
Causal relationship of genetically predicted particulate matter 2.5 level with Alzheimer's disease and the mediating effect of dehydroepiandrosterone sulphate.
Fuente:Annals of Human Biology
Extracto:
Our findings affirm a significant causal association between PM2.5 exposure and
AD, with DHEAS playing a mediating role in this relationship.
institución:(a) Department of Cardiology, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Southern Medical University, Guangzhou, China. (b) Research Department of Medical Sciences, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Southern Medical University, Guangzhou, China.
Racial Discrimination and Metabolic Syndrome in Young Black Adults.
Racial Discrimination and Metabolic Syndrome in Young Black Adults.
Fuente:Jama Network Open
Tipo de trabajo:Estudio de cohortes
Extracto:
AND RELEVANCE: This study suggests
that racial discrimination in late adolescence is associated with MetS among
Black young adults through biobehavioral pathways. Thus, health interventions for
MetS in Black adults will need to contend with sleep behaviors and inflammatory
intermediaries as well as address and reduce exposure to racial discrimination to
narrow disparities and promote health equity.
Cita:JAMA Netw Open 2024 Apr 1; 7 (4) : e245288.
Autor/es:Heard-Garris, Nia (a) Yu, Tianyi (b)
institución:(a) Department of Pediatrics, Northwestern University Feinberg School of Medicine, Chicago, Illinois. (b) Division of Advanced General Pediatrics and Primary Care, Department of Pediatrics, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois.
Therapeutic education of patients with coronary heart disease: Impact of digital platform monitoring in preventing major cardiovascular events in Tunisia: Study protocol.
Therapeutic education of patients with coronary heart disease: Impact of digital platform monitoring in preventing major cardiovascular events in Tunisia: Study protocol.
institución:(a) Faculty of Medicine of Sousse, University of Sousse, Sousse, Tunisia. (b) Department of Prevention and Security of Care, Sahloul University Hospital, Sousse, Tunisia.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Evaluating the efficacy and safety of mavacamten in hypertrophic cardiomyopathy
Evaluating the efficacy and safety of mavacamten in hypertrophic cardiomyopathy
Fuente:Plos One
Tipo de trabajo:Revisión sistemática
Extracto:
Mavacamten influences
diverse facets of HCM comprehensively. Notably, our study delved into the drug's
impact on the heart's structural and functional aspects, providing insights that
complement prior findings. Further large-scale trials are needed to evaluate the
safety profile of Mavacamten.
Cita:PLoS One 2024; 19 (4) : e0301704.
Autor/es:Vyas, Rahul (a) Panchal, Viraj (b)
institución:(a) Department of Internal Medicine, Louisiana State University, Shreveport, Louisiana, United States of America. (b) Department of Medicine, Smt. NHL Municipal Medical College and SVPISMR, Ahmedabad, Gujarat, India.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Deep phenotyping of dementia in a multi-ethnic cardiovascular cohort: The Multi-Ethnic Study of Atherosclerosis (MESA).
Deep phenotyping of dementia in a multi-ethnic cardiovascular cohort: The Multi-Ethnic Study of Atherosclerosis (MESA).
Fuente:Plos One
Extracto:
In a deeply
phenotyped cardiovascular cohort we identified the key correlates of dementia
beyond age as subclinical atherosclerosis and myocyte damage, vascular function,
inflammation, physical activity, hepatic steatosis, and history of cancer.
Cita:PLoS One 2024; 19 (4) : e0298952.
Autor/es:Ostovaneh, Mohammad R (a) Hughes, Timothy M (b)
institución:(a) Division of Cardiology, Department of Medicine, Johns Hopkins University, Baltimore, Maryland, United States of America. (b) Department of Gerontology and Geriatric Medicine, Wake Forest School of Medicine, Winston-Salem, North Carolina, United States of America.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Effect of AGTR1 A1166C genetic polymorphism on coronary artery lesions and mortality in patients with acute myocardial infarction.
Effect of AGTR1 A1166C genetic polymorphism on coronary artery lesions and mortality in patients with acute myocardial infarction.
Fuente:Plos One
Extracto:
The AGTR1 A1166C genetic polymorphism is associated with
very severe luminal stenosis of the LAD but not with mortality in AMI patients.
Cita:PLoS One 2024; 19 (4) : e0300273.
Autor/es:Tran, Duy Cong (a) Le, Linh Hoang Gia (b)
institución:(a) Department of Internal Medicine, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, Vietnam. (b) Department of Cardiology, Cho Ray Hospital, Ho Chi Minh City, Vietnam.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Gender health gaps in guideline-based inpatient cardiovascular medical and nursing care and implementation strategies to reduce the gap (HeartGap): A mixed methods study protocol.
Gender health gaps in guideline-based inpatient cardiovascular medical and nursing care and implementation strategies to reduce the gap (HeartGap): A mixed methods study protocol.
Fuente:Plos One
Tipo de trabajo:Revisión
Extracto:
TRIAL REGISTRATION: The
study is registered in the German Register of Clinical Studies (DRKS) under study
number DRKS00031317.
institución:(a) Institute for Epidemiology, Social Medicine and Health Systems Research, Hannover Medical School, Hanover, Germany. (b) figus-Research Institute for Health- and System Design, Cologne, Germany.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Rising trend and regional disparities of the global burden of disease attributable to ambient low temperature, 1990-2019: An analysis of data from the Global Burden of Disease 2019 study.
Rising trend and regional disparities of the global burden of disease attributable to ambient low temperature, 1990-2019: An analysis of data from the Global Burden of Disease 2019 study.
Fuente:Journal of Global Health
Extracto:
Our findings emphasise the
significance of raising public awareness and prioritising policies to protect
global population health from the adverse effects of low temperatures, even in
the face of global warming. Particular efforts should be targeted towards
individuals with underlying diseases (e.g. cardiovascular diseases) and
vulnerable countries or regions (e.g. Central Asia and central Europe).
Cita:J Glob Health 2024 Apr 19; 14 : 04017.
Autor/es:Liu, Jiangdong (a) Li, Mengmeng (b)
institución:(a) Department of Environmental Health, School of Public Health, Key Lab of Public Health Safety of the Ministry of Education, NHC Key Lab of Health Technology Assessment, IRDR ICoE on Risk Interconnectivity and Governance on Weather/Climate Extremes Impact and Public Health, Fudan University, Shanghai, China. (b) State Key Laboratory of Organ Failure Research, Department of Biostatistics, School of Public Health, Southern Medical University, Guangzhou, China.
Conflicto:Disclosure of interest: The authors completed the ICMJE Disclosure of Interest Form (available upon request from the corresponding author) and disclose no relevant interests.
Exploring acupuncture as a treatment for insomnia in perimenopausal women with stable angina pectoris: A protocol for a randomized, double-blind, placebo-controlled clinical trial.
Exploring acupuncture as a treatment for insomnia in perimenopausal women with stable angina pectoris: A protocol for a randomized, double-blind, placebo-controlled clinical trial.
Fuente:Plos One
Tipo de trabajo:Estudio clínico
Extracto:
Registered 19 November 2022.
Cita:PLoS One 2024; 19 (4) : e0301827.
Autor/es:Shi, Rui (a) Meng, Wenyi (b)
institución:(a) Department of School of Traditional Chinese Medicine, Changchun University of Chinese Medicine, Changchun, China. (b) TCM Cardiovascular Clinical Medicine Research Center of Jilin Province, Changchun, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Role of oral health in heart and vascular health: A population-based study.
Role of oral health in heart and vascular health: A population-based study.
Fuente:Plos One
Extracto:
Oral health improvement may reduce the risk of cardiac
conditions. This underscores oral health's role in multidisciplinary disease
management.
Cita:PLoS One 2024; 19 (4) : e0301466.
Autor/es:Ghanem, Amr Sayed (a) Németh, Orsolya (b)
institución:(a) Department of Health Informatics, Institute of Health Sciences, Faculty of Health Sciences, University of Debrecen, Debrecen, Hungary. (b) Department of Community Dentistry, Faculty of Dentistry, Semmelweis University, Budapest, Hungary.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Cardiovascular outcomes following hospitalisation for exacerbation of bronchiectasis: a territory-wide study.
Cardiovascular outcomes following hospitalisation for exacerbation of bronchiectasis: a territory-wide study.
Fuente:Bmj Open Respiratory Research
Tipo de trabajo:Estudio de cohortes
Extracto:
Patients who
were hospitalised for exacerbation of bronchiectasis were at significantly
increased risk of AMI, CHF and CVE over a 5-year follow-up period.
Claves:Bronchiectasis
Cita:BMJ Open Respir Res 2024 Apr 18; 11 (1)
Autor/es:Kwok, Wang Chun (a) Tsui, Chung Ki (b)
institución:(a) Department of Medicine, The University of Hong Kong, Pok Fu Lam, Hong Kong. (b) Department of Medicine, The University of Hong Kong, Pok Fu Lam, Hong Kong.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
institución:(a) Department of Thoracic Surgery and Oncology, the First Affiliated Hospital of Guangzhou Medical University, Guangzhou Institute of Respiratory Health, State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou, China. (b) Department of Thoracic Surgery and Oncology, the First Affiliated Hospital of Guangzhou Medical University, Guangzhou Institute of Respiratory Health, State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Late-stage meta-C-H alkylation of pharmaceuticals to modulate biological properties and expedite molecular optimisation in a single step.
Late-stage meta-C-H alkylation of pharmaceuticals to modulate biological properties and expedite molecular optimisation in a single step.
Fuente:Nature Communications
Extracto:
Moreover, productive late-stage modulation of key biological characteristics of
drug candidates upon remote C-H alkylation proves viable, highlighting the major
benefits of our approach to offer in drug development programmes.
Cita:Nat Commun 2024 Apr 18; 15 (1) : 3349.
Autor/es:Guillemard, Lucas (a) Ackermann, Lutz (b)
institución:(a) Medicinal Chemistry, Research and Early Development, Cardiovascular, Renal and Metabolism (CVRM), BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden. (b) Institut für Organische und Biomolekulare Chemie and Wöhler Research Institute for Sustainable Chemistry (WISCh), Georg-August-Universität Göttingen, Göttingen, Germany. lutz.ackermann@chemie.uni-goettingen.de.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Detecting m(6)A at single-molecular resolution via direct RNA sequencing and realistic training data.
Detecting m(6)A at single-molecular resolution via direct RNA sequencing and realistic training data.
Fuente:Nature Communications
Extracto:
Compared
to existing methods, mAFiA also demonstrates improved accuracy in measuring
site-level m(6)A stoichiometry in biological samples.
Cita:Nat Commun 2024 Apr 18; 15 (1) : 3323.
Autor/es:Chan, Adrian (a) Naarmann-de Vries, Isabel S (b)
institución:(a) Klaus Tschira Institute for Integrative Computational Cardiology, University of Heidelberg, Heidelberg, Germany. (b) Klaus Tschira Institute for Integrative Computational Cardiology, University of Heidelberg, Heidelberg, Germany.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Extracto:
Hence, nsWHcs can be
considered a key component in order to advance EP-CMR towards the ultimate goal
of targeted substrate-based ablation procedures.
institución:(a) Department of Electrophysiology, HELIOS Heart Center Leipzig at University of Leipzig, Struempellstr. 39, 04289, Leipzig, Germany. (b) Department of Electrophysiology, HELIOS Heart Center Leipzig at University of Leipzig, Struempellstr. 39, 04289, Leipzig, Germany.
Conflicto:Christian Stehning and Jouke Smink are employees of Philips Healthcare. All other authors declare no competing interests.
Impact of insertion into the left internal jugular vein in chemoport-associated infections: a retrospective single-center study of 1690 cases.
Impact of insertion into the left internal jugular vein in chemoport-associated infections: a retrospective single-center study of 1690 cases.
Fuente:Scientific Reports
Extracto:
Using the right internal jugular vein rather than the left internal
jugular vein when performing chemoport insertion might reduce subsequent
infections.
institución:(a) Medical Research Institute, Pusan National University, Busan, Republic of Korea. (b) Department of Thoracic and Cardiovascular Surgery, Pusan National University School of Medicine, Biomedical Research Institute, Pusan National University Hospital, Busan, Republic of Korea.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación