Exploration of the application potential of serum multi-biomarker model in colorectal cancer screening.

Exploration of the application potential of serum multi-biomarker model in colorectal cancer screening.

Fuente:Scientific Reports

Extracto: A screening model incorporating ApoA1, ApoA2, LCA, and CEA provides valuable insights for detecting CRC.

Claves:Bile acid, Colorectal cancer, Lipid, Screening model

Cita:Sci Rep 2024 May 2; 14 (1) : 10127.

Autor/es:Xu, Runhao (a)
Shen, Jianan (b)

institución:(a) Department of Clinical Laboratory, Renji Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200001, China.
(b) Department of Clinical Laboratory, Renji Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200001, China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1038/s41598-024-60867-0

Elevated serum homocysteine levels associated with poor recurrence-free and overall survival in patients with colorectal cancer.

Fuente:Scientific Reports

Extracto: HCY-based prognostic models are effective tools for a comprehensive evaluation of prognosis.

Claves:Colorectal cancer, Homocysteine, Malnutrition, Nomogram, Prognostic

Cita:Sci Rep 2024 May 2; 14 (1) : 10057.

Autor/es:Xie, Hailun (a)
Wei, Lishuang (b)

institución:(a) Department of Gastrointestinal Gland Surgery, The First Affiliated Hospital, Guangxi Medical University, 6 Shuangyong Road, Nanning, 530021, Guangxi, People's Republic of China.
(b) Guangxi Key Laboratory of Enhanced Recovery After Surgery for Gastrointestinal Cancer, Nanning, 530021, Guangxi, People's Republic of China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1038/s41598-024-60855-4

Exosomal miR-493 suppresses MAD2L1 and induces chemoresistance to intraperitoneal paclitaxel therapy in gastric cancer patients with peritoneal metastasis.

Fuente:Scientific Reports

Extracto: Exo-miR-493 may be a biomarker for chemoresistance and prognosis of GC patients with PM and may also be a promising therapeutic target.

Cita:Sci Rep 2024 May 2; 14 (1) : 10075.

Autor/es:Makinoya, Masahiro (a)
Miyatani, Kozo (b)

institución:(a) Division of Gastrointestinal and Pediatric Surgery, Department of Surgery, School of Medicine, Tottori University Faculty of Medicine, 36-1 Nishi-cho, Yonago, 683-8504, Japan.
(b) Division of Gastrointestinal and Pediatric Surgery, Department of Surgery, School of Medicine, Tottori University Faculty of Medicine, 36-1 Nishi-cho, Yonago, 683-8504, Japan. kozo5963@tottori-u.ac.jp.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1038/s41598-024-60967-x

Systematic review and meta-analysis: the efficacy and safety of radiofrequency ablation for early superficial esophageal squamous cell neoplasia.

Systematic review and meta-analysis: the efficacy and safety of radiofrequency ablation for early superficial esophageal squamous cell neoplasia.

Fuente:Bmc Gastroenterology

Tipo de trabajo:Metanálisis

Extracto: For early superficial ESCN, endoscopic RFA achieved both higher 12-month complete remission and late complication postoperatively when compared to 3-month histological CR and acute AEs separately, while the stricture was encountered most commonly. The choice between endoscopic RFA and ESD remains inconclusive.

Claves:Early superficial esophageal squamous cell neoplasia, Endoscopic radiofrequency ablation, Endoscopic submucosal dissection, Meta-analysis

Cita:BMC Gastroenterol 2024 May 2; 24 (1) : 152.

Autor/es:Cheng, Hsu-En (a)
Shiu, Sz-Iuan (b)

institución:(a) Division of Gastroenterology and Hepatology, Department of Internal Medicine, Taichung Veterans General Hospital, No. 1650 Taiwan Boulevard Sect. 4, Taichung, 40705, Taiwan.
(b) Division of Gastroenterology and Hepatology, Department of Internal Medicine, Taichung Veterans General Hospital, No. 1650 Taiwan Boulevard Sect. 4, Taichung, 40705, Taiwan. b9002007@hotmail.com.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12876-024-03250-7

Haemorrhoidal disease in pregnancy: results from a self-assessment questionnaire administered by means of a social network.

Fuente:Bmc Gastroenterology

Extracto: Although with the limitations posed by the nature of our retrospective study via a self-assessment interview, our results suggest that the occurrence of HD in pregnancy seems not sustained by the classical risk factors observed in the general population. At the moment, specific therapeutic measures are lacking and treatment relies on empiric suggestions concerning diet, fluid intake, bowel care, local ointment. Further studies are needed in order to identify a targeted etiologic treatment.

Claves:Anal symptoms, Haemorrhoids, Maternal health, Pregnancy, Social media

Cita:BMC Gastroenterol 2024 May 2; 24 (1) : 150.

Autor/es:D'Alfonso, Angela (a)
De Carolis, Francesca (b)

institución:(a) Unit of Obstetrics and Gynaecology, Department of Life, Health and Environmental Sciences, University of L'Aquila, L'Aquila, Italy.
(b) Surgical Coloproctology, University of L'Aquila, Hospital Val Vibrata, Sant'Omero, TE, Italy.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12876-024-03228-5

Gut microbiota and inflammatory factor characteristics in major depressive disorder patients with anorexia.

Gut microbiota and inflammatory factor characteristics in major depressive disorder patients with anorexia.

Fuente:Bmc Psychiatry

Extracto: This study suggested that MDD patients with anorexia had a distinct gut microbiota compared to healthy individuals, with higher level of CRP. Blautia was more abundant in MDD patients with anorexia and positively correlated with CRP, HAMD scores, and anorexia. The gut microbiota might have influenced MDD and anorexia through the inflammatory factor CRP.

Claves:Anorexia, Gut microbiota, Inflammatory factors, Major depressive disorder

Cita:BMC Psychiatry 2024 May 2; 24 (1) : 334.

Autor/es:Guo, Fengtao (a)
Jing, Lin (b)

institución:(a) Department of Psychiatry, First Hospital of Shanxi Medical University, Taiyuan, 030001, China.
(b) Shanxi Medical University, Taiyuan, 030001, China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12888-024-05778-0

Stapled versus hand-sewn anastomoses after bowel resection in patients with crohn disease.

Stapled versus hand-sewn anastomoses after bowel resection in patients with crohn disease.

Fuente:Bmc Surgery

Extracto: Our analysis showed that there were no differences in anastomotic leak, nor postoperative complications, mortality, reoperation for operative complications, or postoperative hospital stay between the stapler anastomosis and handsewn anastomosis groups.

Claves:Colorectal surgery, Crohn Disease, Postoperative complications, Stapler Versus Hand-Sewn Anastomosis

Cita:BMC Surg 2024 May 3; 24 (1) : 130.

Autor/es:Lahes, Saleh (a)
Fischer, Celine (b)

institución:(a) Department of Surgery, University Hospital Knappschaftskrankenhaus Bochum, Ruhr- University Bochum, In der Schornau 23-25, Bochum, Germany. saleh.lahes@ruhr-uni-bochum.de.
(b) Department of General, Visceral, Vascular and Pediatric Surgery, Saarland University, Homburg/Saar, Germany.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12893-024-02410-6

Proton pump inhibitors use is associated with a higher prevalence of kidney stones: NHANES 2007-2018.

Proton pump inhibitors use is associated with a higher prevalence of kidney stones: NHANES 2007-2018.

Fuente:Bmc Public Health

Extracto: Our study revealed that PPIs use is associated with a higher prevalence of kidney stones for the US population, primarily among women, non-Hispanic whites, individuals with low education levels and individuals with low household income levels. Further studies are required to confirm our findings.

Claves:Calcium oxalate, Kidney stones, National Health and Nutrition Examination Survey, Proton pump inhibitors

Cita:BMC Public Health 2024 May 2; 24 (1) : 1215.

Autor/es:Zhang, Youjie (a)
Liu, Minghui (b)

institución:(a) Department of Urology, Xiangya Hospital, Central South University, Changsha, 410008, China.
(b) National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12889-024-18710-8

Colonic lymphomatous polyposis mantle cell lymphoma

Colonic lymphomatous polyposis mantle cell lymphoma

Fuente:Journal of Medical Case Reports

Tipo de trabajo:Revisión

Extracto: Multiple lymphomatous polyposis is a rare entity characterized by the presence of numerous gastrointestinal polyploid lesions sometimes involving several segments of the gastrointestinal tract. Typical lymphoma presenting as lymphomatous polyposis is mantle cell lymphoma; although, other tumors may have this aspect.

Claves:Colon, Lymphoma, Mantle cell lymphoma, Polyposis

Cita:J Med Case Rep 2024 May 3; 18 (1) : 219.

Autor/es:Djiwa, Toukilnan (a)
Koui, B B S (b)

institución:(a) Department of Pathological Anatomy, Teaching Hospital of Lomé, BP 1515, Lomé, Togo. constantdjiwa@gmail.com.
(b) Department of Pathological Anatomy, Teaching Hospital of Treichville, Abidjan, Ivory Coast.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s13256-024-04533-z

The causality of gut microbiota on onset and progression of sepsis: a bi-directional Mendelian randomization analysis.

The causality of gut microbiota on onset and progression of sepsis: a bi-directional Mendelian randomization analysis.

Fuente:Frontiers in Immunology

Extracto: This MR analysis unveiled a causality between the 21 bacterial traits and sepsis and sepsis-related outcomes. Our findings may help the development of novel microbiota-based therapeutics to decrease the morbidity and mortality of sepsis.

Claves:Mendelian randomization, causal relationship, genetics, gut microbiota, sepsis

Cita:Front Immunol 2024; 15 : 1266579.

Autor/es:Gao, Yuzheng (a)
Liu, Lidan (b)

institución:(a) Department of Anesthesia, ShengJing Hospital of China Medical University, Shenyang, Liaoning, China.
(b) Department of Anesthesia, ShengJing Hospital of China Medical University, Shenyang, Liaoning, China.

Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3389/fimmu.2024.1266579

A comprehensive dataset on biomechanics and motor control during human walking with discrete mechanical perturbations.

A comprehensive dataset on biomechanics and motor control during human walking with discrete mechanical perturbations.

Fuente:Peerj

Extracto: This data can be useful for identifying neural feedback control in human gait, biologically inspired control systems for robots, and the development of clinical applications.

Claves:Biomechanics, Electromyography, Gait, Motor control, Reflexes

Cita:PeerJ 2024; 12 : e17256.

Autor/es:Lorenz, Dana L (a)
van den Bogert, Antonie J (b)

institución:(a) Department of Chemical and Biomedical Engineering, Cleveland State University, Cleveland, Ohio, United States.
(b) Department of Mechanical Engineering, Cleveland State University, Cleveland, Ohio, United States.

Conflicto:Antonie J. van den Bogert is an Academic Editor for PeerJ.

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.7717/peerj.17256

Do asymptomatic STEC-long-term carriers need to be isolated or decolonized? New evidence from a community case study and concepts in favor of an individualized strategy.

Do asymptomatic STEC-long-term carriers need to be isolated or decolonized? New evidence from a community case study and concepts in favor of an individualized strategy.

Fuente:Frontiers in Public Health

Extracto: In the present community case study, we report new observations in long-term shedding of various STEC strains and review the current evidence in favor of risk-adjusted concepts.

Claves:EHEC, HUS, STEC, Shigatoxin, fecal shedding, long-term carriage, social restrictions, socio-economic burden

Cita:Front Public Health 2024; 12 : 1364664.

Autor/es:Sayk, Friedhelm (a)
Hauswaldt, Susanne (b)

institución:(a) Department of Medicine I, Division of Gastroenterology and Nephrology, University Hospital Schleswig-Holstein, Lübeck, Germany.
(b) Department of Infectious Diseases and Microbiology, University Hospital Schleswig-Holstein, Lübeck, Germany.

Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3389/fpubh.2024.1364664

Impact of sarcopenia on variceal rebleeding in patients after endoscopic therapy

Impact of sarcopenia on variceal rebleeding in patients after endoscopic therapy

Fuente:Annals of Medicine

Tipo de trabajo:Estudio de cohortes

Extracto: Sarcopenia was significantly associated with a high 2-year rebleeding rate in liver cirrhosis patients after endoscopic treatment. Therefore, the precise evaluation of a patient's nutritional status, including sarcopenia becomes mandatory before endoscopic treatment.

Claves:Liver cirrhosis, endoscopic therapy, rebleeding, sarcopenia

Cita:Ann Med 2024 Dec; 56 (1) : 2349180.

Autor/es:Liu, Yongshuai (a)
Chang, Huijun (b)

institución:(a) Department of Gastroenterology, Qilu Hospital of Shandong University, Jinan, Shandong, China.
(b) Department of Gastroenterology, Qilu Hospital of Shandong University, Jinan, Shandong, China.

Conflicto:No potential conflict of interest was reported by the author(s).

Formato:Informe impreso

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1080/07853890.2024.2349180

Peritoneal dialysis in an end-stage renal disease patient with massive ascites and primary liver cancer.

Peritoneal dialysis in an end-stage renal disease patient with massive ascites and primary liver cancer.

Fuente:Renal Failure

Extracto: PD can serve as an efficacious therapeutic approach for such late-stage patients afflicted together with severe cirrhosis, massive ascites and primary liver cancer.

Claves:Liver cirrhosis, ascites, end-stage renal disease, peritoneal dialysis, primary liver cancer

Cita:Ren Fail 2024 Dec; 46 (1) : 2347461.

Autor/es:Sun, Lulu (a)
Liang, Chunmei (b)

institución:(a) Department of Nephrology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
(b) Department of Nephrology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

Conflicto:No potential conflict of interest was reported by the authors.

Formato:Informe impreso

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1080/0886022X.2024.2347461

Critical COVID-19, Victivallaceae abundance, and celiac disease: A mediation Mendelian randomization study.

Critical COVID-19, Victivallaceae abundance, and celiac disease: A mediation Mendelian randomization study.

Fuente:Plos One

Extracto: In conclusion, our analysis provides genetic evidence supporting the causal connection between critical COVID-19 and lower Victivallaceae abundance, thereby increasing the risk of celiac disease.

Cita:PLoS One 2024; 19 (5) : e0301998.

Autor/es:Zou, Yuxin (a)
Pan, Manyi (b)

institución:(a) Department of Respiratory and Critical Care Medicine, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
(b) Department of Respiratory and Critical Care Medicine, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Conflicto:The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1371/journal.pone.0301998

PHES scores have limited impact on the risk of overt HE in patients with minimal HE.

PHES scores have limited impact on the risk of overt HE in patients with minimal HE.

Fuente:Hepatology Communications

Extracto: Abnormal PHES is associated with a higher OHE risk, but we found no stepwise increase in OHE risk with worse PHES results below the established cutoff.

Cita:Hepatol Commun 2024 May 1; 8 (5)

Autor/es:Gairing, Simon Johannes (a)
Mangini, Chiara (b)

institución:(a) Department of Internal Medicine I, University Medical Center of the Johannes Gutenberg-University, Mainz, Germany.
(b) Cirrhosis Center Mainz (CCM), University Medical Center of the Johannes Gutenberg-University, Mainz, Germany.

Conflicto:Simon Johannes Gairing: Travel expenses: Ipsen and Gilead. Research grant: Schwiete Stiftung. Joachim Labenz: Consulting: Alphasigma, Norgine. Lecture fees: Norgine. Peter R. Galle: Lecture fees and consulting: Merz Pharmaceuticals. Patricia P. Bloom: Research grant from Vedanta Biosciences. Consultant for Nexilico. Cristina Ripoll: Lecture fees: Falk, Gore, Grifols, CSL Behring. Research grants: DFG, Schwiete Stiftung. Dominique Thabut: Lecture fees: Alfasigma, Abbvie,... Gilead. Christian Labenz: Travel expenses and consulting: Norgine, Merz Pharmaceuticals. Lecture fees: Norgine, Merz Pharmaceuticals. Research grants: Norgine, Merz Pharmaceuticals, Schwiete Stiftung. The remaining authors have no conflicts to report.

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1097/HC9.0000000000000438

Home exercise, branched-chain amino acids, and probiotics improve frailty in cirrhosis

Fuente:Hepatology Communications

Tipo de trabajo:Estudio clínico aleatorizado

Extracto: A long-term multifactorial intervention that included exercise at home, branched-chain amino acids, and a multistrain probiotic improved frailty in outpatients with cirrhosis and was associated with a decrease in the incidence of clinical events such as falls and emergency room visits.

Cita:Hepatol Commun 2024 May 1; 8 (5)

Autor/es:Román, Eva (a)
Kaür, Naujot (b)

institución:(a) University Nursing School EUI-Sant Pau, Barcelona, Spain.
(b) Department of Gastroenterology, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.

Conflicto:German Soriano received grants from Mendes and Grifols. The remaining authors have no conflicts to report.

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1097/HC9.0000000000000443

Acute watery diarrhoea cases during cholera outbreak in Syria

Acute watery diarrhoea cases during cholera outbreak in Syria

Fuente:Bmj Open

Tipo de trabajo:Estudio de cohortes

Extracto: The study found results consistent with previous AWD outbreaks in developing countries like Yemen, Nigeria and Lebanon. Preventative measures like improving water sanitation and hygiene practices are essential to prevent future outbreaks and ease the strain on healthcare systems. Therefore, future studies must investigate the risk factors that increase the spread and the severity of the disease and investigate the best management method.

Claves:GASTROENTEROLOGY, Gastrointestinal infections, INFECTIOUS DISEASES, Public health

Cita:BMJ Open 2024 May 3; 14 (5) : e082385.

Autor/es:Arnaout, Ahmad Yamen (a)
Nerabani, Yaman (b)

institución:(a) University of Aleppo Faculty of Medicine, Aleppo, Aleppo Governorate, Syrian Arab Republic yamen.arnout@gmail.com.
(b) University of Aleppo Faculty of Medicine, Aleppo, Aleppo Governorate, Syrian Arab Republic.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1136/bmjopen-2023-082385

Role of Gut Microbe Composition in Psychosocial Symptom Response to Exercise Training in Breast Cancer Survivors (ROME) study

Fuente:Bmj Open

Tipo de trabajo:Estudio aleatorizado y controlado

Extracto: TRIAL REGISTRATION NUMBER: ClinicalTrials.gov, NCT04088708.

Claves:Breast tumours, Exercise Test, MICROBIOLOGY, ONCOLOGY

Cita:BMJ Open 2024 May 3; 14 (5) : e081660.

Autor/es:Little, Rebecca B (a)
Carter, Stephen J (b)

institución:(a) Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA.
(b) Department of Kinesiology, Indiana University Bloomington, Bloomington, Indiana, USA.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1136/bmjopen-2023-081660

Changes of PK/PD of Meropenem in patients with abdominal septic shock and exploration of clinical rational administration plan: a prospective exploratory study.

Changes of PK/PD of Meropenem in patients with abdominal septic shock and exploration of clinical rational administration plan: a prospective exploratory study.

Fuente:Scientific Reports

Extracto: Further research is needed to confirm this exploratory result.

Claves:Intensive care, Meropenem, Monte Carlo simulation, Pharmacokinetics/pharmacodynamics, Septic shock

Cita:Sci Rep 2024 May 3; 14 (1) : 10173.

Autor/es:Wang, Youquan (a)
Li, Hongxiang (b)

institución:(a) Department of Critical Care Medicine, The First Hospital of Jilin University, Chaoyang District, Changchun City, 130021, Jilin Province, China.
(b) Department of Critical Care Medicine, The First Hospital of Jilin University, Chaoyang District, Changchun City, 130021, Jilin Province, China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1038/s41598-024-60909-7