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Sociedad Iberoamericana de Información Científica (SIIC) selects
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The increasing number of Open Access articles widens the reading offer
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SIIC created, produced and handles the AFT software that deciphers
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Anticancer properties and metabolomic profiling of Shorea roxburghii extracts toward gastrointestinal cancer cell lines.
Anticancer properties and metabolomic profiling of Shorea roxburghii extracts toward gastrointestinal cancer cell lines.
Fuente:Bmc Complementary Medicine and Therapies
Extracto:
This study highlights the potential of natural compounds in
Shorea roxburghii in the development of more effective and safer anticancer
agents as options for GIC as well as shedding light on new avenues for cancer
treatment.
institución:(a) Biomedical Sciences Program, Graduate School, Khon Kaen University, Khon Kaen, Thailand. (b) Regional Medical Sciences Center 2 Phitsanulok, Department of Medical Sciences, Ministry of Public Health, Phitsanulok, Thailand.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Latent profiles of fatigue in inflammatory bowel disease.
Latent profiles of fatigue in inflammatory bowel disease.
Fuente:Bmc Gastroenterology
Extracto:
Latent profile analysis identifies four classes of fatigue in an IBD
cohort with associations with specific risk factors for fatigue along with
specific IBD and demographic attributes. This has implications for the
classification of fatigue in IBD and treatment algorithms.
institución:(a) Department of Gastroenterology, Southern Adelaide Local Health Network (SALHN), Flinders Medical Centre, Flinders Drive, Bedford Park, 5042, SA, Australia. alex.barnes@sa.gov.au. (b) College of medicine and public health, Flinders University, Bedford Park, SA, Australia. alex.barnes@sa.gov.au.
Conflicto:Jane M Andrews: Speakers fees, and Ad Boards from: Abbott, AbbVie, Allergan, Anatara, AstraZeneca, Bayer, BMS 2020, Celegene, Celltrion, Falk, Ferring, Gilead, Hospira, Im-muninc, ImmunsanT, Janssen, MSD, Nestle, Novartis, Progen-ity, Pfizer, Sandoz, Shire, Takeda, Vifor, RAH research Fund, The Hospital Research Fund 2020-2022, The Helmsley Trust 2020-2023. Reme Mountifield: Speakers fees, and Ad Boards from: Abbott, AbbVie, Allergan, Anatara, AstraZeneca,...
Bayer, BMS 2020, Celegene, Celltrion, Falk, Ferring, Gilead, Hospira, Im-muninc, ImmunsanT, Janssen, MSD, Nestle, Novartis, Progen-ity, Pfizer, Sandoz, Shire, Takeda. Rob V Bryant: has received Grant/Research support/Speaker fees (all paid to employer for research support): AbbVie, Ferring, Janssen, Shire, Takeda, Emerge Health; shareholder in BiomebankNo conflict of interest: Alex Barnes, Sutapa Mukherjee, Paul Spizzo, Barbara Toson.
Mycophenolate-induced colitis in a patient with lupus nephritis
Mycophenolate-induced colitis in a patient with lupus nephritis
Fuente:Journal of Medical Case Reports
Tipo de trabajo:Revisión
Extracto:
The purpose of this paper is to report a
case of early-onset MMF-induced colitis in a patient with lupus nephritis who had
started MMF as induction therapy. A review of the available literature on this
uncommon immunosuppressive effect is also presented.
institución:(a) Rheumatology Unit, Internal Medicine Department, King Abdul-Aziz Specialist Hospital, Taif, Saudi Arabia. Alakkas.ziyad@gmail.com. (b) Rheumatology Unit, Internal Medicine Department, King Fahad Hospital, Jeddah, Saudi Arabia.
Conflicto:The authors declare that there is no competing interests.
Application and value of anxiety and depression scale in patients with functional dyspepsia.
Application and value of anxiety and depression scale in patients with functional dyspepsia.
Fuente:Bmc Psychology
Tipo de trabajo:Orientaciones y guía
Extracto:
PHQ-9, SAS, HAMD, and HAMA scales have good application performance in FD
patients. They can assist gastroenterologists in evaluating anxiety and
depression symptoms, and provide reference and guidance for subsequent treatment.
institución:(a) The Second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University, 1111 East Wenzhou Dadao, Longwan District, Wenzhou, 325000, Zhejiang, China. (b) The Second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University, 1111 East Wenzhou Dadao, Longwan District, Wenzhou, 325000, Zhejiang, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
institución:(a) Key Laboratory of Microbiology and Parasitology of Education Department of Guizhou, Guizhou Medical University, Guiyang 561113, Guizhou Province, China. (b) Key Laboratory of Endemic and Ethnic Diseases of Ministry of Education, Guizhou Medical University, Guiyang 561113, Guizhou Province, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Drug-induced mucosal alterations observed during esophagogastroduodenoscopy.
Drug-induced mucosal alterations observed during esophagogastroduodenoscopy.
Fuente:World Journal of Gastroenterology
Extracto:
This minireview aims to provide essential
information on drug-induced mucosal alterations observed on
esophagogastroduodenoscopy, along with representative endoscopic images.
institución:(a) Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama 700-8558, Japan. pr145h2k@okayama-u.ac.jp. (b) Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama 700-8558, Japan.
Conflicto:Conflict-of-interest statement: Iwamuro M has received lecture fees from Otsuka Pharmaceutical Co., Ltd. and Ono Pharmaceutical Co., Ltd., as well as grants from Taisho Pharmaceutical Co., Ltd., Zeria Pharmaceutical Co., Ltd., Mochida Pharmaceutical Co., Ltd., and Abbott Japan Co., Ltd. Kawano S has received lecture fees from Otsuka Pharmaceutical Co., Ltd., Takeda Pharmaceutical Company Limited, Astellas Pharma Inc., AstraZeneca PLC,...
Viatris Inc., Zeria Pharmaceutical Co., Ltd., and EA Pharma Co., Ltd., along with grants from Taisho Pharmaceutical Co., Ltd., Zeria Pharmaceutical Co., Ltd., Mochida Pharmaceutical Co., Ltd., and Abbott Japan Co., Ltd. Otsuka M has received lecture fees from Chugai Pharmaceutical Co., Ltd., Gilead Sciences, Inc., Merck & Co., Inc., Otsuka Pharmaceutical Co., Ltd., Takeda Pharmaceutical Company Limited, AbbVie GK, EA Pharma Co., Ltd., and Kowa Company, Ltd., along with grants from Taisho Pharmaceutical Co., Ltd., Zeria Pharmaceutical Co., Ltd., Mochida Pharmaceutical Co., Ltd., and Abbott Japan Co., Ltd.
institución:(a) Department of Gastroenterology, First Hospital of China Medical University, Shenyang 110001, Liaoning Province, China. (b) Department of Gastroenterology, First Hospital of China Medical University, Shenyang 110001, Liaoning Province, China.
Conflicto:Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
MicroRNAs in inflammatory bowel disease: What do we know and what can we expect?
MicroRNAs in inflammatory bowel disease: What do we know and what can we expect?
Fuente:World Journal of Gastroenterology
Extracto:
Discoveries regarding the
influence of miRNAs on the inflammatory process and the exploration of their role
in gene regulation are expected to provide a basis for the use of miRNAs not only
as potent biomarkers in IBD but also as therapeutic targets for the control of
inflammatory processes in personalized medicine.
Autor/es:de Oliveira, Ellen Cristina Souza (a) Quaglio, Ana Elisa Valencise (b)
institución:(a) Department of Internal Medicine, Medical School, São Paulo State University (Unesp), Botucatu 18618-686, São Paulo, Brazil. (b) Verum Ingredients, Botucatu Technology Park, Botucatu 18605-525, São Paulo, Brazil.
Conflicto:Conflict-of-interest statement: The authors report having no relevant conflicts of interest for this article.
institución:(a) Department of Otorhinolaryngology Head and Neck Surgery, China-Japan Union Hospital of Jilin University, Changchun 130033, Jilin Province, China. (b) Department of Ultrasound, China-Japan Union Hospital of Jilin University, Changchun 130033, Jilin Province, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Preoperative prediction of perineural invasion of rectal cancer based on a magnetic resonance imaging radiomics model: A dual-center study.
Preoperative prediction of perineural invasion of rectal cancer based on a magnetic resonance imaging radiomics model: A dual-center study.
Fuente:World Journal of Gastroenterology
Extracto:
The
CR model based on preoperative MRI radiomics features and clinical risk factors
can preoperatively predict the PNI status of RC noninvasively, which facilitates
individualized treatment of RC patients.
Claves:Magnetic resonance imaging, Nomogram, Perineural invasion, Radiomics, Rectal cancer
institución:(a) Department of Radiology, The Affiliated Hospital of North Sichuan Medical College, Nanchong 637000, Sichuan Province, China. (b) Department of Radiology, The Affiliated Hospital of North Sichuan Medical College, Nanchong 637000, Sichuan Province, China.
Conflicto:Conflict-of-interest statement: The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
Evaluation of mucosal-associated invariant T-cells as a potential biomarker to predict infection risk in liver cirrhosis.
Evaluation of mucosal-associated invariant T-cells as a potential biomarker to predict infection risk in liver cirrhosis.
Fuente:Plos One
Tipo de trabajo:Revisión
Extracto:
Relatively preserved MAIT cell levels in blood of patients with
cirrhosis were associated with a somewhat higher risk of bacterial infections.
The clinical relevance of this might not be strong. MAIT cells might however be
an interesting biomarker to explore in future studies.
Cita:PLoS One 2024; 19 (5) : e0294695.
Autor/es:Bengtsson, Bonnie (a) Maucourant, Christopher (b)
institución:(a) Department of Internal Medicine, Section of Gastroenterology, Södersjukhuset, Stockholm, Sweden. (b) Unit of Gastroenterology and Rheumatology, Department of Medicine Huddinge, Karolinska Institutet, Stockholm, Sweden.
Conflicto:HH reports research funding to his institution from Astra Zeneca, EchoSens, Gilead, Intercept, MSD, Novo Nordisk and Pfizer. Board advisory for BMS. All outside the current work. BB, CM, JKS, and NKB report no conflict of interest. This does not alter our adherence to PLOS ONE policies on sharing data and materials.
Functional dyspepsia: How to manage the burn and the bloat.
Functional dyspepsia: How to manage the burn and the bloat.
Fuente:Cleveland Clinic Journal of Medicine
Extracto:
The authors
discuss how to diagnose and treat both subtypes.
Cita:Cleve Clin J Med 2024 May 1; 91 (5) : 301-307.
Autor/es:Gabbard, Scott (a) Vijayvargiya, Nina (b)
institución:(a) Department of Gastroenterology, Hepatology, and Nutrition, Digestive Disease Institute, Cleveland Clinic, Cleveland, OH; Assistant Professor, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH gabbars@ccf.org. (b) Emory University, Atlanta, GA.
Risk factors for asthma-related hospital and intensive care admissions in children, adolescents and adults
Risk factors for asthma-related hospital and intensive care admissions in children, adolescents and adults
Fuente:Bmj Open Respiratory Research
Tipo de trabajo:Estudio de cohortes
Extracto:
There are significant sociodemographic inequalities
in the rates of asthma-related hospital and ICU admissions. Treating age-specific
modifiable risk factors should be considered an integral part of asthma
management, which could potentially reduce the rate of avoidable hospital
admissions.
institución:(a) University of Birmingham Institute of Applied Health Research, Birmingham, UK. (b) Birmingham Women's and Children's Hospitals NHS Foundation Trust, Birmingham, UK p.nagakumar@bham.ac.uk.
Conflicto:Competing interests: SH reports receiving funding from NIHR and UKRI. KN has been awarded research grants from NIHR, UKRI/MRC, Kennedy Trust for Rheumatology Research, Health Data Research UK, Wellcome Trust, European Regional Development Fund, Institute for Global Innovation, Boehringer Ingelheim, Action Against Macular Degeneration Charity, Midlands Neuroscience Teaching and Development Funds, South Asian Health Foundation, Vifor Pharma, College of Police...
and CSL Behring, with all payments made to his academic institution; KN received consulting fees from BI, Sanofi, CEGEDIM, MSD and holds a leadership/fiduciary role with NICST, a charity and OpenClinical, a Social Enterprise. AHM received personal and institution funds for talks, consultancy fees, education or research grants from GSK, AZ, Sanofi, Teva, BI, Novartis, Chiesi. NJA reports receiving funding from NIHR outside the submitted work. PN reports receiving grants from NIHR and fees for educational talks and consultancy from Novartis, GSK and Astrazaneca.
Autor/es:Lenti, Marco Vincenzo (a) Ballesio, Alessia (b)
institución:(a) Department of Internal Medicine and Medical Therapeutics, University of Pavia, Pavia, Italy. (b) Department of Internal Medicine, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
A patient-based iPSC-derived hepatocyte model of alcohol-associated cirrhosis reveals bioenergetic insights into disease pathogenesis.
A patient-based iPSC-derived hepatocyte model of alcohol-associated cirrhosis reveals bioenergetic insights into disease pathogenesis.
Fuente:Nature Communications
Extracto:
These findings suggest that differences in
mitochondrial bioenergetics and lipid droplet formation are intrinsic to AC
hepatocytes and can play a role in its pathogenesis.
institución:(a) Laboratory of Neurogenetics, National Institute on Alcohol Abuse and Alcoholism, NIH, Bethesda, MD, 20892, USA. (b) Laboratory of Neurogenetics, National Institute on Alcohol Abuse and Alcoholism, NIH, Bethesda, MD, 20892, USA.
Conflicto:The authors do not have any financial and non-financial interest in design or preparation of the manuscript. D.M. receives a salary from Leica Microsystems where he is Manager for Aivia Software, however received no compensation to assist for this manuscript. A.J.S. have stock options in Genfit, Akarna, Tiziana, Durect Inversago, and Galmed. He has served as a consultant to Astra...
Zeneca, Salix, Tobira, Takeda, Jannsen, Gilead, Terns, Birdrock, Merck, Valeant, Boehringer Ingelheim, Bristol Myers Squibb, Lilly, Hemoshear, Novartis, Novo Nordisk, Pfizer, 89 bio, Regeneron, Alnylam, Akero, Tern, Histoindex, Corcept, Poxel, Path AI, and Genfit. His institution has received grant support from Gilead, Salix, Tobira, Bristol Myers, Shire, Intercept, Merck, Astra Zeneca, Malinckrodt and Novartis. He receives royalties from Elsevier and UptoDate. However, A.J.S. received no compensation from any source for this manuscript.
Long non-coding RNA LOXL1-AS1: a potential biomarker and therapeutic target in human malignant tumors.
Long non-coding RNA LOXL1-AS1: a potential biomarker and therapeutic target in human malignant tumors.
Fuente:Clinical and Experimental Medicine
Extracto:
These findings suggest that LOXL1-AS1 may be both a reliable
biomarker and a potential therapeutic target for cancers.
Claves:Biomarker, Cancer, LOXL1-AS1, Long non-coding RNA, Therapeutic target
Cita:Clin Exp Med 2024 May 2; 24 (1) : 93.
Autor/es:Fu, Xiao-Ping (a) Ji, Chun-Yan (b)
institución:(a) Department of Health Management Center, Hubei Provincial Hospital of Traditional Chinese Medicine, Hongshan District, 856 Luoyu Road, Wuhan, 430070, People's Republic of China. (b) Department of Gastroenterology, Hubei Provincial Hospital of Traditional Chinese and Western Medicine, Wuhan, 430015, People's Republic of China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Sexual and gender minority content in undergraduate medical education in the United States and Canada: current state and changes since 2011.
Sexual and gender minority content in undergraduate medical education in the United States and Canada: current state and changes since 2011.
Fuente:Bmc Medical Education
Extracto:
Compared to a 2011 study, the median reported time dedicated to
LGBTQI + health-related topics in 2022 increased across US and Canadian UME
institutions, but the breadth, efficacy, or quality of instruction continued to
vary substantially. Despite the increased hours, this still falls short of the
number of hours based on recommended LGBTQI + health competencies from the
Association of American Medical Colleges. While most deans of medical education
reported their institutions' coverage of LGBTQI + health as 'fair,' 'good,' or
'very good,' there continues to be a call from UME leadership to increase
curricular content. This requires dedicated training for faculty and students.
Claves:LGBTQ persons, Undergraduate medical education
Cita:BMC Med Educ 2024 May 1; 24 (1) : 482.
Autor/es:Streed, Carl G Jr (a) Michals, Amy (b)
institución:(a) Section of General Internal Medicine, Department of Medicine, Boston University Chobanian and Avedisian School of Medicine, 801 Massachusetts Ave., Room 2082, Boston, MA, 02118, USA. Carl.Streed@bmc.org. (b) GenderCare Center, Boston Medical Center, Boston, MA, USA. Carl.Streed@bmc.org.
Conflicto:Dr. Streed received consultation fees from EverlyWell, L’Oreal, the Research Institute for Gender Therapeutics, and the Texas Health Institute on topics unrelated to this work. Dr. Obedin-Maliver received consultation fees from Ibis Reproductive Health, Hims Inc., Folx Health Inc., and Sage Therapeutics on topics unrelated to this work. Dr. Lunn received consultation fees from Hims Inc., Folx Health Inc., Otsuka...
ka Pharmaceutical Development and Commercialization, Inc., and the American Dental Association on topics unrelated to this work.
Autor/es:Tikhomirova, Alexandra (a) McNabb, Emmylee R (b)
institución:(a) Biomedicine Discovery Institute, Department of Microbiology, Monash University, Melbourne, VIC, 3800, Australia. (b) Biomedicine Discovery Institute, Department of Microbiology, Monash University, Melbourne, VIC, 3800, Australia.