Enhancing colorectal cancer prevention: a national assessment of public awareness in Egypt.

Enhancing colorectal cancer prevention: a national assessment of public awareness in Egypt.

Fuente:Bmc Public Health

Extracto: In general, there was a lack of awareness about Colorectal cancer among the Egyptian population especially among rural and lower educational levels, and more health education campaigns are required to enhance CRC prevention efforts in Egypt.

Claves:Bowel cancer awareness measures, Colorectal cancer, Egypt, Knowledge, Prevention, Public awareness, Risk factors

Cita:BMC Public Health 2024 May 27; 24 (1) : 1415.

Autor/es:Yehia, Sania Ali (a)
Alboraie, Mohamed (b)

institución:(a) Department of Epidemiology and Preventive Medicine, National Liver Institute, Menoufia University, Menoufia, Egypt.
(b) Department of Internal Medicine Al-Azhar University, Cairo, Egypt.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12889-024-18746-w

Feasibility of middle colic artery as a landmark for superior mesenteric artery - first approach in laparoscopic pancreatoduodenectomy: a prospective study.

Feasibility of middle colic artery as a landmark for superior mesenteric artery - first approach in laparoscopic pancreatoduodenectomy: a prospective study.

Fuente:World Journal of Surgical Oncology

Tipo de trabajo:Estudio clínico

Extracto: Exposing MCA first helps determine SMA, J1A and IPDA safely, efficiently and faciliates SMA-first approach LPD from the left and complete dissection of the mesopancreas and lymph nodes.

Claves:Artery-first approach, Laparoscopic pancreaticoduodenectomy, Middle colic artery

Cita:World J Surg Oncol 2024 May 28; 22 (1) : 141.

Autor/es:Nguyen, Ham Hoi (a)
Nguyen, Thanh Khiem (b)

institución:(a) Hanoi Medical University, Hanoi, Vietnam.
(b) Center of Gastrointestinal and Hepato-Pancreato-Biliary Surgery, Bach Mai Hospital, Hanoi, Vietnam.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12957-024-03416-3

Urinary polycyclic aromatic hydrocarbon metabolites and hyperlipidemia: NHANES 2007-2016.

Urinary polycyclic aromatic hydrocarbon metabolites and hyperlipidemia: NHANES 2007-2016.

Fuente:Lipids in Health and Disease

Extracto: The cross-sectional analysis identified a significant correlation between urinary PAH metabolite and hyperlipidemia prevalence within the US demographic, with 2-hydroxynaphthalene being the predominant influencer. These findings underscore the need to mitigate PAH exposure as a preventive measure for hyperlipidemia.

Claves:Cross-sectional study, Hyperlipidemia, Polycyclic aromatic hydrocarbons, Urinary PAH metabolites

Cita:Lipids Health Dis 2024 May 27; 23 (1) : 160.

Autor/es:Ye, Chenle (a)
Liu, Yuanrun (b)

institución:(a) Division of Gastroenterology, Institute of Digestive Disease of Guangzhou Medical University, Affiliated Qingyuan Hospital, Guangzhou Medical University, Qingyuan People's Hospital, Qingyuan, 511518, China.
(b) Division of Gastroenterology, Institute of Digestive Disease of Guangzhou Medical University, Affiliated Qingyuan Hospital, Guangzhou Medical University, Qingyuan People's Hospital, Qingyuan, 511518, China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12944-024-02153-6

Integrated analysis of tumor-associated macrophages and M2 macrophages in CRC: unraveling molecular heterogeneity and developing a novel risk signature.

Integrated analysis of tumor-associated macrophages and M2 macrophages in CRC: unraveling molecular heterogeneity and developing a novel risk signature.

Fuente:Bmc Medical Genomics

Extracto: Our research offers a thorough investigation into the molecular mechanisms associated with TAM-M2 macrophages in CRC and unveils potential therapeutic targets, offering new insights for treatment strategies in colorectal cancer.

Claves:Colorectal cancer, M2 macrophages, Risk signature, Tumor-associated macrophages, scRNA-seq

Cita:BMC Med Genomics 2024 May 27; 17 (1) : 145.

Autor/es:Shi, Lujing (a)
Mao, Hongtun (b)

institución:(a) Department of Gastroenterology Surgery, Shengli Oilfield Central Hospital, Dgongying, Shandong, P. R. China.
(b) Department of Gastroenterology Surgery, Shengli Oilfield Central Hospital, Dgongying, Shandong, P. R. China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12920-024-01881-z

Gastrointestinal Surgical Outcomes Study (GISOS)

Gastrointestinal Surgical Outcomes Study (GISOS)

Fuente:Bmj Open

Tipo de trabajo:Estudio de cohortes

Extracto: The findings of this study indicated that postoperative mortality and complications were alarmingly high, which highlights the need for innovative solutions to lower postoperative mortality and complications.

Claves:Colorectal surgery, Hepatobiliary surgery, Mortality, SURGERY

Cita:BMJ Open 2024 May 24; 14 (5) : e084280.

Autor/es:Awedew, Atalel Fentahun (a)
Asefa, Zelalem (b)

institución:(a) Department of Surgery, Debre Tabor University, Debre Tabor, Ethiopia atalel.fentahun@aau.edu.et.
(b) Department of Surgery, Addis Ababa University, Addis Ababa, Ethiopia.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1136/bmjopen-2024-084280

Gut microbiota, inflammatory proteins and COVID-19: a Mendelian randomisation study.

Gut microbiota, inflammatory proteins and COVID-19: a Mendelian randomisation study.

Fuente:Frontiers in Immunology

Extracto: Suggesting a genetic causation between specific gut microbiota and COVID-19, our present research emphasizes the underlying mediating role of CCL2, an inflammatory factor, and contributes to a deeper understanding of the mechanism of action underlying COVID-19.

Claves:COVID-19, Mendelian randomization, gut microbiota, inflammatory proteins, meta

Cita:Front Immunol 2024; 15 : 1406291.

Autor/es:Chen, Yuling (a)
Chen, Chang (b)

institución:(a) Department of Clinical Laboratory, Nanchong Central Hospital (Nanchong Hospital of Beijing Anzhen Hospital, Capital Medical University), The Second Clinical Medical College of North Sichuan Medical College, Nanchong, Sichuan, China.
(b) Medical Department, Nanchong Guoning Mental Health Hospital, Nanchong, Sichuan, China.

Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3389/fimmu.2024.1406291

Loss of RAB25 Cooperates with Oncogenes in the Transformation of Human Mammary Epithelial Cells (HMECs) to Give Rise to Claudin-Low Tumors.

Loss of RAB25 Cooperates with Oncogenes in the Transformation of Human Mammary Epithelial Cells (HMECs) to Give Rise to Claudin-Low Tumors.

Fuente:Biomed Research International

Extracto: Our findings reveal that RAB25 functions as a tumor suppressor gene, and loss of RAB25 could serve as a novel biomarker of the claudin-low type of TNBC.

Cita:Biomed Res Int 2024; 2024 : 8544837.

Autor/es:Joshi, Pooja (a)
Ayyagari, Vijayalakshmi (b)

institución:(a) Arrakis Therapeutics, Waltham, MA, USA.
(b) Department of Obstetrics and Gynecology, Southern Illinois University School of Medicine, Springfield, IL 62702, USA.

Conflicto:The authors have no relevant conflicts of interest to disclose.

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1155/2024/8544837

Causal relationships between gut microbiota and lymphoma: a bidirectional Mendelian randomization study.

Causal relationships between gut microbiota and lymphoma: a bidirectional Mendelian randomization study.

Fuente:Frontiers in Cellular and Infection Microbiology

Extracto: Our MR analysis revealed substantial causal associations between gut microbiota and lymphoma, offering new insights into lymphoma prevention and management microbiota.

Claves:Hodgkin lymphoma, Mendelian randomization, causal association, gut microbiota, non-Hodgkin lymphoma

Cita:Front Cell Infect Microbiol 2024; 14 : 1374775.

Autor/es:Liang, Jing (a)
Liu, Gengqiu (b)

institución:(a) Pediatric Hematology Laboratory, Division of Hematology/Oncology, Department of Pediatrics, The Seventh Affiliated Hospital of Sun Yat-Sen University, Shenzhen, Guangdong, China.
(b) Department of Thoracic Surgery, The Seventh Affiliated Hospital, Sun Yat-sen University, Shenzhen, Guangdong, China.

Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3389/fcimb.2024.1374775

Assessment of medical information on irritable bowel syndrome information in Wikipedia and Baidu Encyclopedia: comparative study.

Assessment of medical information on irritable bowel syndrome information in Wikipedia and Baidu Encyclopedia: comparative study.

Fuente:Peerj

Extracto: Wikipedia provides more reliable, higher quality, and more objective IBS-related health information than the Baidu Encyclopedia. However, there should be improvements in the information quality for both sites. Medical professionals and institutions should collaborate with these online platforms to offer better health information for IBS.

Claves:Baidu encyclopedia, DISCERN instrument, Functional gastrointestinal disorder, Health information, Irritable bowel syndrome, Wikipedia

Cita:PeerJ 2024; 12 : e17264.

Autor/es:Li, Xi (a)
Chen, Kexin (b)

institución:(a) General Practice ward/ International Medical Center Ward, General Practice Medical Center, West China Hospital of Sichuan University, Chengdu, Sichuan, China.
(b) Lab of Inflammatory Bowel Disease, Frontiers Science Center for Disease-Related Molecular Network, Chengdu, Sichuan, China.

Conflicto:The authors declare there are no competing interests.

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.7717/peerj.17264

Robotic, transanal, and laparoscopic total mesorectal excision for locally advanced mid/low rectal cancer

Robotic, transanal, and laparoscopic total mesorectal excision for locally advanced mid/low rectal cancer

Fuente:Bjs Open

Tipo de trabajo:Estudio multicéntrico

Extracto: In this multicentre, retrospective, propensity score-matched, cohort study of patients with locally advanced rectal cancer, newer minimally invasive approaches (robotic TME and transanal TME) demonstrated improved outcomes compared with laparoscopic TME.

Cita:BJS Open 2024 May 8; 8 (3)

Autor/es:de'Angelis, Nicola (a)
Marchegiani, Francesco (b)

institución:(a) Unit of Robotic and Minimally Invasive Digestive Surgery, Department of Surgery, Ferrara University Hospital, Ferrara (Cona), Italy.
(b) Unit of Colorectal and Digestive Surgery, DIGEST Department, Beaujon University Hospital (AP-HP), Clichy, France.

Formato:Informe impreso

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1093/bjsopen/zrae044

Mediation Mendelian randomisation study on the effects of shift work on coronary heart disease and traditional risk factors via gut microbiota.

Mediation Mendelian randomisation study on the effects of shift work on coronary heart disease and traditional risk factors via gut microbiota.

Fuente:Journal of Global Health

Extracto: Our findings suggest a causal effect of JSW on CHD, diabetes, and hypertension. We also found evidence for a significant connection between JSW and alterations in the gut microbiota. Considering that certain microbial taxa mediated the effect of JSW on hypertension risk, targeting gut microbiota through therapeutics could potentially mitigate high risks of hypertension and CHD associated with JSW.

Cita:J Glob Health 2024 May 28; 14 : 04110.

Autor/es:Zhang, Yun (a)
Zhao, Lingyun (b)

institución:Zhang, Yun (a)
Zhao, Lingyun (b)

Conflicto:Disclosure of interest: The authors completed the ICMJE Disclosure of Interest Form (available upon request from the corresponding author) and disclose no relevant interests.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Scotland

Sitio web:http://dx.doi.org/10.7189/jogh.14.04110

Prognostic significance of chronic kidney disease and impaired renal function in Japanese patients with COVID-19.

Prognostic significance of chronic kidney disease and impaired renal function in Japanese patients with COVID-19.

Fuente:Bmc Infectious Diseases

Extracto: Clinicians should consider pre-existing CKD and impaired renal function at the time of COVID-19 diagnosis for the management of COVID-19.

Claves:COVID-19, Estimated glomerular filtration rate, Japanese population, Renal insufficiency

Cita:BMC Infect Dis 2024 May 25; 24 (1) : 527.

Autor/es:Tanaka, Hiromu (a)
Chubachi, Shotaro (b)

institución:(a) Division of Pulmonary Medicine, Department of Medicine, Keio University School of Medicine, 35 Shinanomachi, Shinjuku, Tokyo, 160-8582, Japan.
(b) Division of Pulmonary Medicine, Department of Medicine, Keio University School of Medicine, 35 Shinanomachi, Shinjuku, Tokyo, 160-8582, Japan. bachibachi472000@z6.keio.jp.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12879-024-09414-w

Structural and functional cardiac parameters across occupations: a cross-sectional study in differing work environments.

Structural and functional cardiac parameters across occupations: a cross-sectional study in differing work environments.

Fuente:Scientific Reports

Extracto: Larger prospective studies are warranted to investigate and delineate differences in structural and functional cardiac parameters across occupational groups, and to discern their associated effects and risks on the cardiovascular health of these distinct professional cohorts.

Claves:Cardiac function, Cardiovascular risk, Echocardiography, Firefighters, Office workers, Police officers

Cita:Sci Rep 2024 May 27; 14 (1) : 12115.

Autor/es:Leischik, Roman (a)
Foshag, Peter (b)

institución:(a) Department of Cardiology, Faculty of Health, School of Medicine, University Witten/Herdecke, 58455, Witten, Germany. prof.leischik@kardiologie.nrw.
(b) Department of Cardiology, Faculty of Health, School of Medicine, University Witten/Herdecke, 58455, Witten, Germany.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1038/s41598-024-62190-0

Genome-wide cross-disease analyses highlight causality and shared biological pathways of type 2 diabetes with gastrointestinal disorders.

Genome-wide cross-disease analyses highlight causality and shared biological pathways of type 2 diabetes with gastrointestinal disorders.

Fuente:Communications Biology

Extracto: These findings support a risk-increasing genetic overlap between T2D and GI disorders (except IBD), implicate shared biological pathways with putative causality for certain T2D - GI pairs, and identify targets for further investigation.

Cita:Commun Biol 2024 May 27; 7 (1) : 643.

Autor/es:Adewuyi, Emmanuel O (a)
Porter, Tenielle (b)

institución:(a) Centre for Precision Health, Edith Cowan University, Joondalup, 6027, Western, Australia. e.adewuyi@ecu.edu.au.
(b) Collaborative Genomics and Translation Group, School of Medical and Health Sciences, Edith Cowan University, Joondalup, 6027, Western, Australia. e.adewuyi@ecu.edu.au.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1038/s42003-024-06333-z

Investigation on the efficiency of lentinan for injection combining cisplatin on treating malignant pleural effusion based on systematic review and meta-analysis.

Fuente:Medicine

Tipo de trabajo:Metanálisis

Extracto: Available evidence suggested the combined use of LNT and cisplatin showed better efficacy in treating MPE without increasing ADR incidence than using cisplatin alone. LNT is an ideal treatment for MPE, which has high clinical application value.

Cita:Medicine (Baltimore) 2024 May 24; 103 (21) : e38032.

Autor/es:Wang, Yixuan (a)
Wang, Haojia (b)

institución:Wang, Yixuan (a)
Wang, Haojia (b)

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe impreso

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1097/MD.0000000000038032

Clinical Applications of the Gut Microbiome in Genitourinary Cancers.

Fuente:American Society of Clinical Oncology Educational Book. American Society of Clinical Oncology. Annual Meeting

Extracto: Novel approaches using probiotic therapy (live bacterial supplementation) and fecal microbiota transplantation in patients with GU cancers are currently under investigation.

Cita:Am Soc Clin Oncol Educ Book 2024 Jun; 44 (3) : e100041.

Autor/es:Nguyen, Charles B (a)
Vaishampayan, Ulka N (b)

institución:(a) Division of Hematology/Oncology, Department of Medicine, University of Michigan, Ann Arbor, MI.
(b) Division of Hematology/Oncology, Department of Medicine, University of Michigan, Ann Arbor, MI.

Formato:Informe impreso

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1200/EDBK_100041

Combination and Optimal Sequencing of Systemic and Locoregional Therapies in Hepatocellular Carcinoma

Fuente:Journal of Vascular and Interventional Radiology Jvir

Tipo de trabajo:Consenso

Extracto: This Research Consensus Panel sought to highlight research priorities pertaining to the combination and optimal sequencing of LRT and systemic therapy, assessing the greatest needs across BCLC stages.

Cita:J Vasc Interv Radiol 2024 Jun; 35 (6) : 818-824.

Autor/es:Thornton, Lindsay M (a)
Abi-Jaoudeh, Nadine (b)

institución:(a) Department of Interventional Radiology, University of Miami, Leonard M. Miller School of Medicine Miami, Florida. Electronic address: lindsay.thornton@miami.edu.
(b) Division of Interventional Radiology, University of California Irvine, Irvine, California.

Formato:Informe impreso

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1016/j.jvir.2024.02.017

Impact of Age on Long-Term Outcomes of Laparoscopic Nissen Fundoplication-A Single Center Study.

Fuente:Medicina (kaunas, Lithuania)

Extracto: In our study, there were no differences found in terms of satisfaction with surgery and associated recommendations between the studied age groups.

Claves:GERD, Nissen fundoplication, elderly, gastroesophageal reflux disease, laparoscopic Nissen fundoplication

Cita:Medicina (Kaunas) 2024 Apr 24; 60 (5)

Autor/es:Dowgiałło-Gornowicz, Natalia (a)
Kacperczyk, Justyna (b)

institución:(a) Department of General, Minimally Invasive and Elderly Surgery, Collegium Medicum, University of Warmia and Mazury, Niepodległosci 44 St., 10-045 Olsztyn, Poland.
(b) Department of Anesthesiology and Intensive Care, Children's Memorial Health Institute, Av. Dzieci Polskich 20, 04-730 Warsaw, Poland.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3390/medicina60050688

Non-Invasive Diagnostic Tests for Portal Hypertension in Patients with HBV- and HCV-Related Cirrhosis

Fuente:Medicina (kaunas, Lithuania)

Tipo de trabajo:Revisión

Extracto: Ongoing research should explore novel biomarkers and novel elastography techniques, but current evidence supports the utility of routine blood tests, LSM, and SSM as effective surrogates in diagnosing and staging portal hypertension and predicting patient outcomes.

Claves:cirrhosis, hepatic decompensation, liver stiffness, non-invasive tests, portal hypertension, spleen stiffness

Cita:Medicina (Kaunas) 2024 Apr 24; 60 (5)

Autor/es:Celsa, Ciro (a)
Veneziano, Marzia (b)

institución:(a) Gastroenterology and Hepatology Unit, Department of Health Promotion, Mother & Child Care, Internal Medicine & Medical Specialties, University of Palermo, 90127 Palermo, Italy.
(b) Department of Surgery & Cancer, Imperial College London, Hammersmith Hospital, London W12 0NN, UK.

Conflicto:C.C. received speaker fees and advisory board honoraria from AstraZeneca, Eisai, Merck Sharp & Dohme, and Ipsen and travel support from Roche. V.C. received advisory board honoraria and/or speaking fees from Abbvie, Advanz, Ipsen, and Echosens. The other authors have no disclosures to declare.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3390/medicina60050690

Prognostic Role of Basal Serum Alpha-Fetoprotein in Patients with Hepatocellular Carcinoma Suitable for Curative Treatment.

Fuente:Medicina (kaunas, Lithuania)

Extracto: Prospective studies are needed to confirm these results.

Claves:AFP cut-off, alpha-fetoprotein, hepatocellular carcinoma, prognosis, survival

Cita:Medicina (Kaunas) 2024 Apr 24; 60 (5)

Autor/es:Mazza, Stefano (a)
Frigerio, Chiara (b)

institución:(a) Gastroenterology and Endoscopy Unit, Fondazione IRCCS Policlinico San Matteo, 27100 Pavia, Italy.
(b) Gastroenterology and Endoscopy Unit, Fondazione IRCCS Policlinico San Matteo, 27100 Pavia, Italy.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3390/medicina60050692