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Access to cancer clinical trials for racialised older adults
Access to cancer clinical trials for racialised older adults
Fuente:Bmj Open
Tipo de trabajo:Revisión
Extracto:
The findings of the scoping review will be
submitted for publication in a peer-reviewed journal and presentation at
international conferences.
Claves:GERIATRIC MEDICINE, Health Equity, ONCOLOGY
Cita:BMJ Open 2024 Jan 19; 14 (1) : e074191.
Autor/es:Li, Vivian (a) Alibhai, Shabbir M H (b)
institución:(a) Lawrence S. Bloomberg Faculty of Nursing, University of Toronto, Toronto, Ontario, Canada. (b) Department of Medicine, University Health Network, Toronto, Ontario, Canada.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
institución:(a) Department of Veterinary Medicine, University of Perugia, Via San Costanzo 4, 06126 Perugia, IT, Italy. Electronic address: margherita.maranesi@unipg.it. (b) Department of Veterinary Medicine, University of Perugia, Via San Costanzo 4, 06126 Perugia, IT, Italy; Department of Philosophy, Social Sciences, and Education, PhD Course in "Ethics of Communication, Scientific Research and Technological Innovation" Medical-Health Curriculum, University of Perugia, Piazza G. Ermini, 1, 06123 Perugia, IT, Italy. Electronic address: elisa.palmioli@studenti.unipg.it.
Conflicto:Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
Extracto:
Despite the tremendous progress made so far, some major
challenges to population-based biobanking still remain, including the need to
develop strategies for the long-term sustainability of biobanks, the handling of
incidental findings, and the linkage of sample-related and sample-derived data to
other relevant resources.
Claves:biobanking, biomarker, biosample, clinical routine, cohort study, governance, health data, phenotype, public involvement, sustainability
Cita:Genes (Basel) 2024 Jan 3; 15 (1)
Autor/es:Lieb, Wolfgang (a) Strathmann, Eike A (b)
institución:(a) Institute of Epidemiology and Biobank Popgen, Kiel University, University Hospital Schleswig-Holstein, Campus Kiel, 24105 Kiel, Germany. (b) German Centre for Lung Research (DZL), Airway Research Centre North (ARCN), 22927 Großhansdorf, Germany.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Embers of the Past: Early Childhood Traumas Interact with Variation in P2RX7 Gene Implicated in Neuroinflammation on Markers of Current Suicide Risk.
Embers of the Past: Early Childhood Traumas Interact with Variation in P2RX7 Gene Implicated in Neuroinflammation on Markers of Current Suicide Risk.
Fuente:International Journal of Molecular Sciences
Extracto:
Our results suggest that P2RX7 variation may
mediate the effect of early childhood adversities and traumas on later emergence
of suicide risk.
institución:(a) Department of Psychiatry and Psychotherapy, Semmelweis University, Balassa utca 6, 1082 Budapest, Hungary. (b) Laboratory of Molecular Pharmacology, HUN-REN Institute of Experimental Medicine, Szigony utca 43, 1083 Budapest, Hungary.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Integrating ethics in AI development: a qualitative study.
Integrating ethics in AI development: a qualitative study.
Fuente:Bmc Medical Ethics
Tipo de trabajo:Orientaciones y guía
Extracto:
The three themes collectively emphasized that beyond being
innovative, AI must genuinely benefit healthcare and its stakeholders, meaning AI
also aligns with intricate and context-specific healthcare practices. Our
findings signal that instead of narrow product-specific AI guidance, ethical AI
development may need a systemic, proactive perspective that includes the ethical
considerations (objectives, actors, and context) and focuses on healthcare
applications. Ethically developing AI involves a complex interplay between AI,
ethics, healthcare, and multiple stakeholders.
Claves:AI, AI development, AI ethics, AI guidance, Artificial intelligence, Implementation, Qualitative research
Cita:BMC Med Ethics 2024 Jan 23; 25 (1) : 10.
Autor/es:Arbelaez Ossa, Laura (a) Lorenzini, Giorgia (b)
institución:(a) Institute for Biomedical Ethics, University of Basel, Basel, Switzerland. laura.arbelaezossa@unibas.ch. (b) Institute for Biomedical Ethics, University of Basel, Basel, Switzerland.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Applications of artificial intelligence in the field of oral and maxillofacial pathology
Applications of artificial intelligence in the field of oral and maxillofacial pathology
Fuente:Bmc Oral Health
Tipo de trabajo:Revisión sistemática
Extracto:
In the field of oral and maxillofacial
pathology, AI has the potential to enhance diagnostic precision, personalize
care, and ultimately improve patient outcomes. The development and application of
AI in healthcare, however, necessitates careful consideration of ethical, legal,
and regulatory challenges. Additionally, because AI is still a relatively new
technology, caution must be taken when applying it to this industry.
institución:(a) Department of OMFS & Diagnostic Sciences, College of Dentistry, Riyadh Elm, University, Riyadh, Saudi Arabia. (b) Department of Oral Medicine and Radiology, People's College of Dental Sciences and Research Centre, People's University, Bhopal, 462037, India. shiva21375@gmail.com.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Multiple Gestation after Elective Single-Embryo Transfer
Multiple Gestation after Elective Single-Embryo Transfer
Fuente:Journal of Pregnancy
Tipo de trabajo:Revisión
Extracto:
The hypotheses
that we have so far remain unproven due to the rarity of zygotic splitting as
well as the ethicolegal considerations of human embryo research. The presence of
such incidents necessitates extensive counselling of the couple.
Cita:J Pregnancy 2024; 2024 : 2686128.
Autor/es:Zhaffal, Mokhamad (a) Al Jafari, Rania (b)
institución:(a) Obstetrics and Gynaecology Department, UAE University, Al Ain, UAE. (b) Fakih Fertility Center, Al Ain, UAE.
Conflicto:The authors declare that there is no conflict of interest regarding the publication of this article.
Automated evaluation of masseter muscle volume: deep learning prognostic approach in oral cancer.
Automated evaluation of masseter muscle volume: deep learning prognostic approach in oral cancer.
Fuente:Bmc Cancer
Extracto:
The sarcopenia assessment method
is useful for predicting the life expectancy of patients with oral cancer. In the
future, it is crucial to validate and analyze various factors within the oral
surgery field, extending beyond cancer patients.
institución:(a) Department of Oral and Maxillofacial Surgery, Graduate School of Dentistry, Osaka University, 1-8 Yamada-Oka, 565-0871, Suita, Osaka, Japan. (b) Department of Oral and Maxillofacial Surgery, Graduate School of Dentistry, Osaka University, 1-8 Yamada-Oka, 565-0871, Suita, Osaka, Japan. hirashins2@gmail.com.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Advancing nursing practice with artificial intelligence: Enhancing preparedness for the future.
Advancing nursing practice with artificial intelligence: Enhancing preparedness for the future.
Fuente:Nursing Open
Extracto:
AI-enabled
robotics and telehealth solutions expand the reach of nursing care, improving
accessibility of healthcare services and remote monitoring capabilities of
patients' health conditions.
institución:(a) Master of Public Health, Bangladesh Open University, Gazipur, Bangladesh. (b) Major of Bangladesh Army, Combined Military Hospital, Dhaka, Bangladesh.
Conflicto:The authors have no competing interest at all.
Comprehensive analysis revealed the immunoinflammatory targets of rheumatoid arthritis based on intestinal flora, miRNA, transcription factors, and RNA-binding proteins databases, GSEA and GSVA pathway observations, and immunoinfiltration typing.
Comprehensive analysis revealed the immunoinflammatory targets of rheumatoid arthritis based on intestinal flora, miRNA, transcription factors, and RNA-binding proteins databases, GSEA and GSVA pathway observations, and immunoinfiltration typing.
Fuente:Hereditas
Extracto:
The findings of this study could
help with RA diagnosis, prognosis, and targeted molecular treatment.
institución:(a) Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, 210029, Jiangsu, China. (b) Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, 210029, Jiangsu, China.
From nature to nanotechnology: The interplay of traditional medicine, green chemistry, and biogenic metallic phytonanoparticles in modern healthcare innovation and sustainability.
From nature to nanotechnology: The interplay of traditional medicine, green chemistry, and biogenic metallic phytonanoparticles in modern healthcare innovation and sustainability.
Extracto:
This exploration
is essential for harnessing the unique properties of metallic nanoparticles to
address pressing challenges and advance innovations across diverse scientific and
industrial domains.
Claves:Cancer mechanisms, Green synthesis, Metal Nanoparticles, Natural compounds, Phytonanoparticles, Synthetic compounds
Cita:Biomed Pharmacother 2024 Jan; 170 : 116083.
Autor/es:Puri, Abhijeet (a) Mohite, Popat (b)
institución:(a) AETs St. John Institute of Pharmacy & Research, Palghar, Maharshtra 401404, India. (b) AETs St. John Institute of Pharmacy & Research, Palghar, Maharshtra 401404, India. Electronic address: mohitepb@gmail.com.
Conflicto:Declaration of Competing Interest The Authors declare no conflict of interest and this study is been presented here for the first time and has not been reported in any previous study.
Extracto:
However, based on
disease pathology, patient's needs, ethical considerations, therapeutic
developmental time lines, and current state of the art of gene therapy for liver
and eye, we have a different view on this issue: We argue below that local
treatment of the eye is the preferred option for GACR.
Cita:EMBO Mol Med 2024 Jan; 16 (1) : 4-7.
Autor/es:Bergen, Arthur A (a) Buijs, Mark Jn (b)
institución:(a) Department of Human Genetics, Section Ophthalmogenetics, Amsterdam UMC, University of Amsterdam, 1105 AZ, Amsterdam, the Netherlands. (b) Department of Ophthalmology, Amsterdam UMC, University of Amsterdam, 1105 AZ, Amsterdam, the Netherlands.
Undisclosed financial conflicts of interest in DSM-5-TR: cross sectional analysis.
Undisclosed financial conflicts of interest in DSM-5-TR: cross sectional analysis.
Fuente:Bmj (clinical Research Ed.)
Tipo de trabajo:Guía
Extracto:
Conflicts of interest among panel members of DSM-5-TR were
prevalent. Because of the enormous influence of diagnostic and treatment
guidelines, the standards for participation on a guideline development panel
should be high. A rebuttable presumption should exist for the Diagnostic and
Statistical Manual of Mental Disorders to prohibit conflicts of interest among
its panel and task force members. When no independent individuals with the
requisite expertise are available, individuals with associations to industry
could consult to the panels, but they should not have decision making authority
on revisions or the inclusion of new disorders.
Cita:BMJ 2024 Jan 10; 384 : e076902.
Autor/es:Davis, Lauren C (a) Diianni, Alexa T (b)
institución:(a) Geisinger Commonwealth School of Medicine, Department of Medical Education, Scranton, PA, USA. (b) Geisinger Commonwealth School of Medicine, Department of Medical Education, Scranton, PA, USA.
Conflicto:Competing interests: All authors have completed the ICMJE uniform disclosure form at www.icmje.org/coi_disclosure.pdf and declare: BJP reports contributing to an osteoarthritis research team supported by Pfizer and Eli Lilly (2019-21) and reports receiving grants from the Pennsylvania Academic Clinical Research Center, outside the submitted work; no support from any organization for the submitted work; no financial relationships with any organizations...
that might have an interest in the submitted work in the previous three years; no other relationships or activities that could appear to have influenced the submitted work.
Extracto:
Additionally, we present case studies to further
illustrate the effectiveness of our approach and provide a deeper understanding
of its underlying principles.
Stevens-Johnson Syndrome in a Patient on Concomitant Treatment with Levetiracetam and Trimethoprim/Sulfamethoxazole.
Stevens-Johnson Syndrome in a Patient on Concomitant Treatment with Levetiracetam and Trimethoprim/Sulfamethoxazole.
Fuente:The American Journal of Case Reports
Extracto:
The concomitant use of Trimethoprim/sulfamethoxazole
and levetiracetam might have been responsible for heightening the potential of
these 2 medications to trigger an unfortunate adverse drug reaction, but no
formal culprit was able to be identified and no in vivo study was performed, due
to ethical considerations. Thus, through this case report we strive to increase
awareness of the potential risk of simultaneously prescribing these 2
medications.
institución:(a) Department of Internal Medicine, HCA Healthcare Citrus Hospital Florida, Inverness, FL, USA. (b) Department of Internal Medicine, HCA Healthcare Citrus Hospital Florida, Inverness, FL, USA.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
End-of-Life Care Preferences of Patients with Advanced Urological Malignancies: An Explorative Survey Study at a Tertiary Referral Center.
End-of-Life Care Preferences of Patients with Advanced Urological Malignancies: An Explorative Survey Study at a Tertiary Referral Center.
Fuente:Current Oncology (toronto, Ont.)
Extracto:
Based on
this finding, physicians and healthcare staff should initiate discussions about
early care planning so that patients in incurable situations can express their
wishes regarding their preferred place of death.
Claves:end of life, palliative care, patient preference, place of death, urological malignancies
Cita:Curr Oncol 2024 Jan 12; 31 (1) : 462-471.
Autor/es:Volberg, Christian (a) Urhahn, Fabian (b)
institución:(a) Department of Anesthesiology and Intensive Care Medicine, University Hospital Marburg, Philipps University Marburg, Baldingerstraße, 35033 Marburg, Germany. (b) Research Group Medical Ethics, Faculty of Medicine, Philipps University Marburg, Baldingerstraße, 35033 Marburg, Germany.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Developing, Purchasing, Implementing and Monitoring AI Tools in Radiology: Practical Considerations. A Multi-Society Statement from the ACR, CAR, ESR, RANZCR and RSNA.
Developing, Purchasing, Implementing and Monitoring AI Tools in Radiology: Practical Considerations. A Multi-Society Statement from the ACR, CAR, ESR, RANZCR and RSNA.
Fuente:Radiology. Artificial Intelligence
Tipo de trabajo:Revisión
Extracto:
It has not undergone review or editing by
this journal.
institución:(a) University College Cork, Cork, Ireland. (b) Department of Radiology, Grandview Medical Center, Birmingham, AL, USA.
Conflicto:Disclosures of conflicts of interest: A.P.B.: member of the Insights into Imaging Scientific Editorial Board. He has not taken part in the review or selection process of this article. B.A.: No competing interests. JC: No competing interests. E.K.: Shareholder Gleamer, Paris and Contextflow, Vienna. N.K.: Consultant for ES3 (aerospace company), consultant for Synapsica Healthcare, partner (equity owner) at Radiology Partners...
(RP), sole or partial owner of several radiology practices managed by RP. RP has a minority interest in AIDOC. RP has an indirect minority interest in Rad AI. Associate Fellow Stanford AIMI Center. Hold several volunteer positions at RSNA, ACR, SIIM and RADequal. J.M.: Consultant, Microsoft (Nuance), Research funding, royalties, GE, Research funding, Siemens, Spouse employment, shareholder Annexon Biosciences, Spouse employment Bristol Meyers Squibb. L.O.R.: No competing interests. D.P.D.S.: member of the Insights into Imaging Scientific Editorial Board. He has not taken part in the review or selection process of this article. A.T.: No competing interests. C.W.: Chair, Commission on Informatics and Member, Board of Chancellors, American College of Radiology. Advisor: Notable Systems, and RadPair. J.S.: No competing interests.
Chain of Thought Utilization in Large Language Models and Application in Nephrology.
Chain of Thought Utilization in Large Language Models and Application in Nephrology.
Fuente:Medicina (kaunas, Lithuania)
Extracto:
It also aims to thoroughly
examine the ethical aspects, clarity, and future possibilities, offering an
in-depth view of the exciting convergence of these areas.
Claves:artificial intelligence, chain-of-thought prompting, decision-making process, enhanced care, large language models (LLMs), nephrology
Cita:Medicina (Kaunas) 2024 Jan 13; 60 (1)
Autor/es:Miao, Jing (a) Thongprayoon, Charat (b)
institución:(a) Division of Nephrology and Hypertension, Department of Medicine, Mayo Clinic, Rochester, MN 55905, USA. (b) Division of Nephrology and Hypertension, Department of Medicine, Mayo Clinic, Rochester, MN 55905, USA.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
mHealth technologies for pregnancy prevention: A challenge for patient-centred contraceptive counselling in Dutch general practice.
mHealth technologies for pregnancy prevention: A challenge for patient-centred contraceptive counselling in Dutch general practice.
Fuente:The European Journal of General Practice
Tipo de trabajo:Guía
Extracto:
To minimise risk of unintended pregnancy, professionals hesitated to
include mHealth contraception or other FABMs in contraceptive consultations. This
may hamper adequate patient-centred counselling for patients with preference for
mHealth contraception.Based on these results, we proposed recommendations that
foster a patient-tailored approach to mHealth contraceptives.
Claves:Contraceptive counselling, mHealth technologies, non-hormonal contraception, patient-centred care, risk minimisation
Cita:Eur J Gen Pract 2024 Dec; 30 (1) : 2302435.
Autor/es:Algera, Ellen (a) Leusink, Peter (b)
institución:(a) Department of Anthropology, Faculty of Social and Behavioural Sciences, University of Amsterdam, Amsterdam, The Netherlands. (b) Department of Ethics, Law & Medical Humanities, Amsterdam University Medical Centers, Faculty of Medicine, University of Amsterdam, Amsterdam, The Netherlands.
Conflicto:No potential conflict of interest was reported by the author(s).
Healthy and Happy? An Ethical Investigation of Emotion Recognition and Regulation Technologies (ERR) within Ambient Assisted Living (AAL).
Healthy and Happy? An Ethical Investigation of Emotion Recognition and Regulation Technologies (ERR) within Ambient Assisted Living (AAL).
Fuente:Science and Engineering Ethics
Extracto:
We highlight four ethical issues that
specifically arise in the context of ERR in AAL systems, namely concerns
regarding (1) the reductionist view of emotions, (2) solutionism as an underlying
assumption of these technologies, (3) the privacy and autonomy of users and their
emotions, (4) the tendency of machine learning techniques to normalise and
generalise human behaviour and emotional reactions.
Autor/es:Hartmann, Kris Vera (a) Rubeis, Giovanni (b)
institución:(a) Institute for the Study of Christian Social Service (DWI), Theological Faculty, Heidelberg University, Karlstr.16, 69117, Heidelberg, Germany. (b) Division Biomedical and Public Health Ethics, Karl Landsteiner University of Health Sciences, Dr.-Karl-Dorrek-Str. 30, Krems, 3500, Austria.
Conflicto:The authors have no conflict of interest to disclose.