Authors' Reports

Uwe Wollina
describes for SIIC the most significant aspects of his article
describe para SIIC los aspectos relevantes de su artículo

How to deal with

Giant non-melanoma skin cancer is defined by large and potentially high-risk tumors. Their management needs an interdisciplinary approach.

The article was published by
El artículo fue publicado por
Journal of Cutaneous and Aesthetic Surgery
Volume / Volumen: 5
Number / Número: 1
First and last pages / Páginas inicial-final: 12-19
Year / Año: 2012
Month / Mes: january

This journal, which is covered by SIIC Data Bases,
is part of the bibliographic collections of the Biblioteca Biomédica (BB) SIIC.
Esta revista, clasificada por SIIC Data Bases,
integra el acervo bibliográfico de la Biblioteca Biomédica (BB) SIIC.

Principal institution where the research took place
Institución principal de la investigación
Department of Dermatology and Allergology, Academic Teaching Hospital Dresden-Friedrichstadt, Dresden, Germany

Authors' Report

Crónica del Autor

Cómo abordarlos
Tumores Gigantes de Piel no Melanomas

Los tumores gigantes de piel, no melanomas, son lesiones grandes y potencialmente de alto riesgo. El tratamiento requiere de un abordaje multidisciplinario.
Crónica del Autor

Imprimir nota

Bibliographic references
Referencias bibliográficas

Archontaki M, Stavrianos SD, Korkolis DP, Arnogiannaki N, Vassiliadis V, Liapakis IE, et al. Giant basal cell carcinoma: clinicopathological analysis of 51 cases and review of the literature. Anticancer Res 29:2655-63, 2009.
Asilian A, Andalib F. Scalp myiasis associated with advanced basal cell carcinoma. Dermatol Surg 35:1539-40, 2009.
Badertscher N, Rosemann T, Tandjung R, Braun RP. minSKIN does a multifaceted intervention improve the competence in the diagnosis of skin cancer by general practitioners? Study protocol for a randomised controlled trial. Trials 12:165, 2011.
Berger U, Hyckel P, Schumann D, Wollina U. Reconstruction of large scalp defects by expander technique. Z Hautkrankh 66:776-82, 1991.
Brantsch KD, Meisner C, Schönfisch B, Trilling B, Wehner-Caroli J, Röcken M, et al. Analysis of risk factors determining prognosis of cutaneous squamous-cell carcinoma: a prospective study. Lancet Oncol 9:713-20, 2008.
Breuninger H, Bootz F, Hauschild A, Kortmann RD, Wolff K, Stockfleth E, et al. Short German guidelines: squamous cell carcinoma. J Dtsch Dermatol Ges 6 (Suppl 1):S5-8, 2008.
Chand M, Armstrong T, Britton G, Nash G. How and why do we measure surgical risk? J Royal Soc Med 100:508-12, 2007.
Chiu CS, Lin CY, Kuo TT, Kuan YZ, Chen MJ, Ho HC, et al. malignant cutaneous tumors of the scalp: a study of demographic characteristics and histologic distributions of 398 Taiwanese patients. J Am Acad Dermatol 56:448-52, 2007.
de Haas ER., Nijsten T, de Vries E. Population education in preventing skin cancer: from childhood to adulthood. J Drugs Dermatol 9:112-6, 2010.
Denewer A, Khater A, Farouk O, Hegazy M, Mosbah M, Hafez M, et al. Can we put a simplified algorithm for reconstruction of large scalp defects following tumor resection? World J Surg Oncol 9:129, 2011.
Edge SB, Byrd DR, Compton CC, Fritz AG, Greene FL, Trotti A. AJCC Cancer Staging Manual. 7th ed. New York, NY: Springer; 2010. Pp. 301-14.
Fattah A, Pollock J, Maheshwar A, Britto JA. Big bad BCCs: craniofacial resection and reconstruction for atypical basal cell carcinoma. J Plast Reconstr Aesthet Surg 63:e433-41, 2010.
Greinert R, Boniol M. Skin cancer - Primary and secondary prevention (information campaigns and screening) - with a focus on children & sunbeds. Prog Biophys Mol Biol 107:473-6, 2011.
Hauschild A, Breuninger H, Kaufmann R, Kortmann RD, Schwipper V, Werner J, et al. Short German guidelines: basal cell carcinoma. J Dtsch Dermatol Ges 6 (Suppl 1):S2-4, 2008.
Holterhues C, Vries E, Louwman MW, Koljenovich S, Nijsten T. Incidence and trends of cutaneous malignancies in the Netherlands, 1989-2005. J Invest Dermatol 130:1807-12, 2010.
Jennings L, Schmults CD. Management of high-risk cutaneous squamous cell carcinoma. J Clin Aesthet Dermatol 3:39-48, 2010.
Lackey PL, Sargent LA, Wong L, Brzezienski M, Kennedy JW. Giant basal cell carcinoma surgical management and reconstructive challenges. Ann Plast Surg 58:250-4, 2007.
Martin RC 2nd, Edwards MJ, Cawte TG, Sewell CL, McMasters KM. Basosquamous carcinoma: analysis of prognostic factors influencing recurrence. Cancer 88:1365-9, 2000.
Moon C, Chae YK, Lee J. Targeting epidermal growth factor receptor in head and neck cancer: lessons learned from cetuximab. Exp Biol Med (Maywood) 235:907-20, 2010.
Raasch BA, Buettner PG, Garbe C. Basal cell carcinoma: histological classification and body-site distribution. Br J Dermatol 155:401-7, 2006.
Rubin AI, Chen EH, Ratner D. Basal-cell carcinoma. N Engl J Med 353:2262-9, 2005.
Staples MP, Elwood M, Burton RC, Williams JL, Marks R, Giles GG. Non-melanoma skin cancer in Australia: the 2002 national survey and trends since 1985. Med J Aust 184:6-10, 2006.
Thomas WO, Harper LL, Wong SG, Harris CN, Parker JA, Abernethy J, et al. Surgical management of giant nonmelanoma skin neoplasia. South Med J 91:190-5, 1998.
Wollina U, Bayyoud Y, Kittner T, Dürig E. Giant tricholemmal squamous cell carcinoma with cranial infiltration. J Clin Aesthet Dermatol 4:34-7, 2011.
Wollina U, Bayyoud Y. Reconstruction of a large scalp defect by the sequential use of dermal substitute, self-filling osmotic tissue expander and rotational flap. J Cutan Aesthet Surg 3:106-10, 2010.
Wollina U, Hansel G, Koch A, Köstler E. Oral capecitabine plus subcutaneous interferon alpha in advanced squamous cell carcinoma of the skin. J Cancer Res Clin Oncol 131:300-4, 2005.
Wollina U, Meseg A, Weber A. Use of a collagen-elastin matrix for hard to treat soft tissue defects. Int Wound J 8:291-6, 2011.
Wollina U, Pabst F, Krönert C, Schorcht J, Haroske G, Klemm E, et al. High-risk basal cell carcinoma: an update. Expert Rev Dermatol 5:357-68, 2010.
Wollina U, Schreiber A, Merla K, Haroske G. Combined cetuximab and volumetric modulated arc-radiotherapy in advanced recurrent squamous cell carcinoma of the scalp. Dermatol Rep 3:e57, 2011.
Wollina U. Massive scalp myiasis with bleeding in a patient with multiple malignancies. Int Wound J 7:297-9, 2010.
Wollina U. One-stage reconstruction of soft tissue defects with the sandwich technique: Collagen-elastin dermal template and skin grafts. J Cutan Aesthet Surg 4:176-82, 2011.
Zoccali G, Pajadan R, Papa P, Orsini G, Lomartire N, Giuliani M. Giant basal cell carcinoma of the skin: literature review and personal experience. J Eur Acad Dermatol Venereol 2012; in press [DOI: 10.1111/j.1468-3083.2011.04427.x].

Other articles written by the author Uwe Wollina
Otros artículos de Uwe Wollina

Leiter U, Buettner PG, Eigentler TK, Bröcker EB, Voit C, Gollnick H, Marsch W, Wollina U, Meier F, Garbe C (2012)How often and how long should cutaneous melanoma patients be followed-up? A hazard rates Based analysis of the German Central Malignant Melanoma Registry in 33,384 patients? J Am Acad Dermatol 66: 37-45. Wollina U (2012)Cutaneous T-cell lymphoma – an update on treatment. Int J Dermatol 51:1019-1036. Wollina U (2012)Cetuximab for cutaneous non-melanoma skin cancer. Expert Opinion Biological Therapy 12: 949-956 Wollina U, Gemmeke A, Koch A (2012)Dissecting cellulitis of the scalp responding to intravenous tumor necrosis factor-alfa antagonist. J Clin Aesthet Dermatol 5:36-39. Wollina U, Heinig B (2012)Novel therapies developed for the treatment of leg ulcers: focus on physical therapies Expert Review of Dermatology 7: 419-427. Wollina U, Tilp M, Meseg A, Schönlebe J, Heinig B, Nowak A (2012) Management of severe anogenital acne inversa (Hidradenitis suppurativa). Dermatol Surg 38: 100-117. Wollina U, Unger L, Haroske G, Heinig B (2012)Classification of vascular disorders in the skin and selected data on new evaluation and treatment. Dermatol Ther 25: 287-296. Wollina U (2011) One-stage reconstruction of soft tissue defects with sandwich technique: collagen-elastin dermal template and skin grafts. J Cutan Aesth Surg 4:176-182. Wollina U, Bayyoud Y, Kittner T, Dürig E (2011) Giant tricholemmal squamous cell carcinoma with cranial infiltration: J Clin Aesthet Dermatol 4:34-37. Wollina U, Goldman A (2011) Hyaluronic acid dermal fillers: Safety and efficacy for the treatment of wrinkels, aging skin, body sculpturing and medical conditions. Clin Med Rev Therapeutics 3: 107-121. Wollina U, Hansel G, Schönlebe J, Averbeck M, Paasch U, Uhl J, Hindemann W, Simon J-C (2011) Cutaneous angiosarcoma is a rare aggressive malignant vascular tumour of the skin. J Eur Acad Dermatol Venereol 25:964-968. Wollina U, Haroske G (2011) Pyoderma gangrenosum. Curr Opin Rheumatol 23: 50-56.

SIIC System of Assisted Editing (SSEA)
/ Sistema SIIC de Edición Asistida (SSEA)

Uwe Wollina was invited by SIIC on
Uwe Wollina fue invitado por SIIC el
2012, november 1
  The authors' report was accepted on
La crónica del autor fue aprobada el
2023, july 26
The authors' report was accepted on
La crónica del autor fue aprobada el
2023, july 26
Published in siicsalud
Publicado en siicsalud
2023, october 24

The article is strictly related to the following sections of siicsalud
El artículo se relaciona estrictamente con las siguientes secciones de siicsalud

/ Anatomía Patológica
/ Dermatología

and secondarily related to the following sections

y secundariamente con las siguientes secciones



General Dermatology
Dermatología General

Oncologic Dermatology
Dermatología Oncológica



Information about the full text
Acerca del trabajo completo

Giant Epithelial Malignancies (Basal Cell Carcinoma, Squamous Cell Carcinoma): A Series of 20 Tumors From a Single Center

Author / Autor
Uwe Wollina1, Yousef Bayyoud2, Claudia Krönert3, Andreas Nowak4

4 Dr. Med., Dept. Of Anaesthesiology And Intensive Care, Emergency Medicine And Pain Management. Academic Teaching Hospital Dresden-friedrichstadt, Head Of Department

Access to the original source

Article URL:
/ URL del artículo:

URL of Abstract:
/ URL del abstract:

URL of Abstract page in Medline:
/ URL del abstract en Medline:

URL of Abstract page in Scielo:
/ URL del abstract en Scielo:

URL of Abstract page in Scopus:
/ URL del abstract en Scopus:

URL of Abstract page in Embase:
/ URL del abstract en Embase:

Other data bases:
/ Otras bases de datos:

siic DB:
/ siic DB: