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Bidyut Chakrobarty
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The role of tobacco, virus and genes in oral cancer.

he prevalence of oral squamous cell carcinoma (OSCC) has significantly increased over decades in several countries and human papilloma virus (HPV) has been indicated as one of the underlying causes. This suggests that HPV plays a role in the early stages of carcinogenesis but is not a requisite for the maintenance and progression of malignant state. p53 is a tumor suppressor gene that checks the cell and promotes apoptosis and cell repair that can be deactivated by mutations and a viral interaction leading to cancer and individuals with particular polymorphic variant of p53 is more susceptible to HPV-induced carcinogenesis. The present study has been carried out to detect and correlate p53 polymorphism/mutation, HPV DNA in the biopsy samples of oral cancer patients who had tobacco habits.

The article was published by
El artículo fue publicado por
Journal of Oral and Maxillofacial Pathology (JOMFP)
Volume / Volumen: 18
Number / Número: 2
First and last pages / Páginas inicial-final: 211-216
Year / Año: 2014
Month / Mes: may

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is part of the bibliographic collections of the Biblioteca Biomédica (BB) SIIC.
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integra el acervo bibliográfico de la Biblioteca Biomédica (BB) SIIC.

Principal institution where the research took place
Institución principal de la investigación
Dr. R Ahmed Dental College, Kolkata,, West Bengal, India

Authors' Report

Crónica del Autor

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Other articles written by the author Bidyut Chakrobarty
Otros artículos de Bidyut Chakrobarty

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Bidyut Chakrobarty was invited by SIIC on
Bidyut Chakrobarty fue invitado por SIIC el
2015, july 24
  The authors' report was accepted on
La crónica del autor fue aprobada el
2017, september 14
The authors' report was accepted on
La crónica del autor fue aprobada el
2017, september 14
Published in siicsalud
Publicado en siicsalud
2017, december 13

The article is strictly related to the following sections of siicsalud
El artículo se relaciona estrictamente con las siguientes secciones de siicsalud

/ Odontología
/ Oncología

and secondarily related to the following sections

y secundariamente con las siguientes secciones

Infectious Diseases

Family Medicine
Medicina Familiar

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Relationship Among Tobacco Habits, Human Papilloma Virus (HPV) Infection, P53 Polymorphism/Mutation and the Risk of Oral Squamous Cell Carcinoma

Author / Autor
Bidyut Chakrobarty1, Jay Gopal Ray2, Divya Uppala3, Sumit Majumdar4

4 Dr, Gitam Dental College, Head Of The Department

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Journal of Oral and Maxillofacial Pathology (JOMFP)

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