Respiratory Syncytial Virus Hospital-Based Burden of Disease in Children Younger Than 5 Years, 2015-2022.

Respiratory Syncytial Virus Hospital-Based Burden of Disease in Children Younger Than 5 Years, 2015-2022.

Fuente:Jama Network Open

Extracto: AND RELEVANCE: Hospitalizations for RSV and bronchiolitis demonstrated atypical seasonality in 2021 and 2022, with an overall increase in RSV encounters. Postpandemic RSV hospitalization increased for all ages, but especially among older children, whereas bronchiolitis hospitalization was decreased or unchanged compared with earlier seasons. These findings suggest some of the observed increase in RSV hospital use may be due to increased testing.

Cita:JAMA Netw Open 2024 Apr 1; 7 (4) : e247125.

Autor/es:Suss, Robert J (a)
Simões, Eric A F (b)

institución:(a) Department of Pediatric Infectious Diseases, University of Colorado School of Medicine and Children's Hospital Colorado, Aurora.
(b) Department of Pediatric Infectious Diseases, University of Colorado School of Medicine and Children's Hospital Colorado, Aurora.

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1001/jamanetworkopen.2024.7125

Health care utilisation of asylum seekers and refugees in the South-West of Germany.

Health care utilisation of asylum seekers and refugees in the South-West of Germany.

Fuente:Plos One

Tipo de trabajo:Estudio de cohortes

Extracto: Though seasonal variation and referral practices must be considered, a high rate of revisits to the ICF were recorded. While visits to the LED decreased after the implementation of the ICF, visits returned to the pre-ICF levels during the routine running of the ICF. The results show that AS&R require reliable access to health care, yet the needs of specific groups of migrants may be different, especially those with language barriers, minority groups or those from certain regions. As such, care should be migrant sensitive and adapt to the changing needs of the population. Though more research is required to better understand the differing needs of migrants, this study may help to inform guidelines surrounding migrant sensitive standards of care in Germany.

Cita:PLoS One 2024; 19 (4) : e0299886.

Autor/es:Bockey, Annabelle J (a)
Braun, Cornelia (b)

institución:(a) Department of Medicine II, Division of Infectious Diseases, Medical Centre-University Hospital Freiburg, Faculty of Medicine, Freiburg, Germany.
(b) PhD Programme "Epidemiology" Braunschweig-Hannover, Helmholtz Centre for Infection Research, Braunschweig, Germany.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1371/journal.pone.0299886

Chronic obstructive pulmonary disease as a risk factor for sarcopenia

Fuente:Plos One

Tipo de trabajo:Revisión sistemática

Extracto: Nursing researchers should pay more attention to the symptomatic management of COPD and encourage patients to participate in daily activities in the early stages of the disease.

Cita:PLoS One 2024; 19 (4) : e0300730.

Autor/es:Yu, Zhenjie (a)
He, Jingchun (b)

institución:(a) School of Nursing, Tianjin Medical University, Tianjin, China.
(b) Department of Respiratory and Critical Care Medicine, Tianjin No. 4 Central Hospital, Tianjin, China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1371/journal.pone.0300730

Pneumococcal vaccination and primary care presentations for acute respiratory tract infection and antibiotic prescribing in older adults.

Fuente:Plos One

Extracto: PPV23 vaccination in older adults may result in a small reduction in the incidence of total ARI presentations in primary care. However, the effect is small and residual confounding cannot be excluded.

Cita:PLoS One 2024; 19 (4) : e0299924.

Autor/es:Hossain, Fariha Binte (a)
Jayasinghe, Sanjay (b)

institución:(a) School of Population Health, UNSW, Sydney, Australia.
(b) National Centre for Immunisation Research and Surveillance (NCIRS), Kids Research, Sydney Children's Hospitals Network, New South Wales, Sydney, Australia.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1371/journal.pone.0299924

Complex bronchopleural fistulas

Complex bronchopleural fistulas

Fuente:The Journal of International Medical Research

Tipo de trabajo:Caso clínico

Extracto: Our treatment method may be a useful reference for treating complex BPF.

Claves:Bronchopleural fistula, bronchoscopy, empyema, endobronchial valve, individualization, interventional therapy

Cita:J Int Med Res 2024 Apr; 52 (4) : 3000605241245269.

Autor/es:Cao, Miaoying (a)
Yi, Jing (b)

institución:(a) Department of Pulmonary Medicine, Shaoxing People's Hospital, Shaoxing, China.
(b) Department of Pulmonary Medicine, Shaoxing People's Hospital, Shaoxing, China.

Conflicto:Declaration of conflicting interestThe authors declare that there is no conflict of interest.

Formato:Informe impreso

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1177/03000605241245269

Krebs von den Lungen-6 levels at admission predicts exercise-induced hypoxemia before and after discharge in patients with COVID-19.

Krebs von den Lungen-6 levels at admission predicts exercise-induced hypoxemia before and after discharge in patients with COVID-19.

Fuente:Respiratory Investigation

Extracto: Some patients with COVID-19 may continue to experience exercise-induced hypoxemia after discharge. Age, lactate dehydrogenase, and Krebs von den Lungen-6 levels at admission could serve as predictive markers of exercise-induced hypoxemia before and after discharge in these patients.

Claves:6-Min walk test, COVID-19, Exercise-induced hypoxemia, KL-6 levels

Cita:Respir Investig 2024 May; 62 (3) : 369-374.

Autor/es:Morikawa, Keisuke (a)
Tabira, Kazuyuki (b)

institución:(a) Department of Rehabilitation, Matsusaka Municipal Hospital, Tonomachi 1550, Matsusaka, Mie, 515-8544, Japan; Department of Health Science, Kio University Graduate School, Umamichu 4-2-2, Kitakatsuragigun-koryocho, Nara, 635-0832, Japan. Electronic address: morikawagacha@yahoo.co.jp.
(b) Department of Health Science, Kio University Graduate School, Umamichu 4-2-2, Kitakatsuragigun-koryocho, Nara, 635-0832, Japan.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe impreso

Idioma:Inglés

País de fuente:Países Bajos

Sitio web:http://dx.doi.org/10.1016/j.resinv.2024.02.011

Rate of severe exacerbations, healthcare resource utilisation and clinical outcomes in patients with COPD in low-income and middle-income countries: results from the EXACOS International Study.

Rate of severe exacerbations, healthcare resource utilisation and clinical outcomes in patients with COPD in low-income and middle-income countries: results from the EXACOS International Study.

Fuente:Bmj Open Respiratory Research

Extracto: DISCUSSION: The findings presented here indicate that effective treatment strategies to prevent severe exacerbations in patients with COPD remain a significant unmet need in low-income and middle-income countries.

Claves:COPD Exacerbations

Cita:BMJ Open Respir Res 2024 Apr 18; 11 (1)

Autor/es:Athanazio, Rodrigo Abensur (a)
Bernal Villada, Laura (b)

institución:(a) Pulmonology Division, Heart Institute-InCor-Clinical Hospital, Faculty of Medicine, Universidade de São Paulo, São Paulo, Brazil rodrigo.athanazio@hc.fm.usp.br.
(b) Respiratory & Immunology, AstraZeneca, Bogota, Colombia.

Conflicto:Competing interests: RAA reports financial support from AstraZeneca, Chiesi, GlaxoSmithKline, Novartis and Boehringer Ingelheim for speaking engagements; and research grants from GlaxoSmithKline and AstraZeneca. LBV is an employee of AstraZeneca. SNA reports financial support from Boehringer Ingelheim for congress attendance and speaking engagements; financial support from Novartis, Teva, AstraZeneca, GlaxoSmithKline and Boehringer Ingelheim for serving as a consultant; and research... grants from AstraZeneca, GlaxoSmithKline and Boehringer Ingelheim. MS reports financial support from GlaxoSmithKline for congress attendance and speaking engagements, and from AstraZeneca for assistance with medical education programmes. JD reports financial support from GlaxoSmithKline for serving as a medical adviser and for congress attendance; research grants from AstraZeneca; financial support from Octapharma for congress attendance and speaking engagements; financial support from Boehringer Ingelheim for congress attendance; and financial support from Grifols for congress attendance. LN-A reports financial support from AstraZeneca, Novartis and Boehringer Ingelheim for congress attendance and speaking engagements; financial support from AstraZeneca, GlaxoSmithKline and Boehringer Ingelheim for serving as a consultant; and research grants from Novartis, GlaxoSmithKline, Boehringer Ingelheim and AstraZeneca. HF is an employee of AstraZeneca and owns stock in AstraZeneca.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1136/bmjresp-2023-002101

Profound hypoxemia and hypotension during posterior spinal fusion in a spinal muscular atrophy child with severe scoliosis

Profound hypoxemia and hypotension during posterior spinal fusion in a spinal muscular atrophy child with severe scoliosis

Fuente:Bmc Anesthesiology

Tipo de trabajo:Caso clínico

Extracto: Spinal fusion surgery is beneficial for SMA patients in preventing scoliosis progression and improving ventilation. However, severe scoliosis and thoracic deformities put them at risk of both hemodynamic and respiratory instability during surgical positioning. When advanced monitoring like TEE is not practical intraoperatively, preoperative imaging may help with differential diagnosis, and guide the surgical positioning to minimize mechanical compression of the thoracic cavity, thereby helping the patient complete the surgery safely.

Claves:Case report, Hypoxemia, Scoliosis, Spinal muscular atrophy, Surgical positioning

Cita:BMC Anesthesiol 2024 Apr 18; 24 (1) : 148.

Autor/es:Shu, Qian (a)
Dong, Yulei (b)

institución:(a) Department of Anesthesiology, Peking Union Medical College Hospital, Beijing, China.
(b) Department of Orthopedic Surgery, Peking Union Medical College Hospital, Beijing, China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12871-024-02537-2

Development and application of a deep learning-based comprehensive early diagnostic model for chronic obstructive pulmonary disease.

Development and application of a deep learning-based comprehensive early diagnostic model for chronic obstructive pulmonary disease.

Fuente:Respiratory Research

Tipo de trabajo:Estudio clínico

Extracto: We developed and implemented a data fusion strategy to construct a state-of-the-art COPD diagnostic model integrating deep learning features, radiomics features, and questionnaire variables. Our data fusion strategy proved effective, and the model can be easily deployed in clinical settings. TRIAL REGISTRATION: Not applicable. This study is NOT a clinical trial, it does not report the results of a health care intervention on human participants.

Claves:COPD, Data fusion, Deep learning, Diagnostic

Cita:Respir Res 2024 Apr 18; 25 (1) : 167.

Autor/es:Zhu, Zecheng (a)
Zhao, Shunjin (b)

institución:(a) Center of Clinical Big Data and Analytics of The Second Affiliated Hospital and Department of Big Data in Health Science School of Public Health, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.
(b) Department of Respiratory and Critical Care Medicine, The Second Affiliated Hospital of Zhejiang University School of Medicine, Lanxi Branch (Lanxi People's Hospital), Hangzhou, Zhejiang, China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12931-024-02793-3

PTMs of PD-1/PD-L1 and PROTACs application for improving cancer immunotherapy.

PTMs of PD-1/PD-L1 and PROTACs application for improving cancer immunotherapy.

Fuente:Frontiers in Immunology

Extracto: PROTACs could be a novel strategy to combine with radiotherapy, chemotherapy and immunotherapy for cancer patients.

Claves:PD-1, PD-L1, PROTAC, immunotherapy, ubiquitination

Cita:Front Immunol 2024; 15 : 1392546.

Autor/es:Ren, Xiaohui (a)
Wang, Lijuan (b)

institución:(a) Department of Respiratory Medicine, Shanxi Province Cancer Hospital/Shanxi Hospital Affiliated to Cancer Hospital, Chinese Academy of Medical Sciences/Cancer Hospital Affiliated to Shanxi Medical University, Taiyuan, Shanxi, China.
(b) Department of Hospice Care, Shanxi Province Cancer Hospital/Shanxi Hospital Affiliated to Cancer Hospital, Chinese Academy of Medical Sciences/Cancer Hospital Affiliated to Shanxi Medical University, Taiyuan, Shanxi, China.

Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3389/fimmu.2024.1392546

Illumina and Nanopore sequencing in culture-negative samples from suspected lower respiratory tract infection patients.

Illumina and Nanopore sequencing in culture-negative samples from suspected lower respiratory tract infection patients.

Fuente:Frontiers in Cellular and Infection Microbiology

Extracto: Both platforms play a certain value in infection diagnosis and pathogen diagnosis of CMT-negative suspected LRTI patients, providing a theoretical basis for clinical accurate diagnosis and symptomatic treatment. The Nanopore platform demonstrated potential advantages in the identification of Mycobacterium and could further provide another powerful approach for patients with suspected Mycobacterium infection.

Claves:Illumina, bronchoalveolar lavage fluid, culture-negative sample, lower respiratory tract infection, metagenomic next-generation sequencing, nanopore

Cita:Front Cell Infect Microbiol 2024; 14 : 1230650.

Autor/es:Ma, Lichao (a)
Zhu, Chi (b)

institución:(a) Department of Pulmonary and Critical Care Medicine, Wuxi Branch, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Wuxi, Jiangsu, China.
(b) State Key Laboratory of Neurology and Oncology Drug Development (Jiangsu Simcere Pharmaceutical Co., Ltd, Jiangsu Simcere Diagnostics Co., Ltd.), Jiangsu, China.

Conflicto:Authors CZ, and FD were employed by Jiangsu Simcere Diagnostics Co., Ltd. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3389/fcimb.2024.1230650

Exploring the impact of dexmedetomidine on short-term outcomes in critically ill sepsis-associated encephalopathy patients.

Exploring the impact of dexmedetomidine on short-term outcomes in critically ill sepsis-associated encephalopathy patients.

Fuente:European Review For Medical and Pharmacological Sciences

Extracto: Dexmedetomidine administration was significantly associated with reduced short-term mortality among patients with sepsis-associated encephalopathy in the ICU. However, it also prolonged ICU and hospital stays and increased the incidence of VAP.

Cita:Eur Rev Med Pharmacol Sci 2024 Apr; 28 (7) : 2724-2736.

Autor/es:Tang, J (a)
Zhong, Z-G (b)

institución:Tang, J (a)
Zhong, Z-G (b)

Formato:Informe impreso

Idioma:Inglés

País de fuente:Italia

Sitio web:http://dx.doi.org/10.26355/eurrev_202404_35901

Factors influencing the therapeutic failure of high-flow nasal cannula oxygen humidification in patients with interstitial pneumonia complicated by respiratory failure.

Fuente:European Review For Medical and Pharmacological Sciences

Extracto: The HFNC failure rate in patients with IP and respiratory failure is 15.8%. Pre-treatment PaO2/FiO2 ratio, CRP, CONUT, and GCS scores are independent factors associated with HFNC treatment failure and warrant clinical attention.

Cita:Eur Rev Med Pharmacol Sci 2024 Apr; 28 (7) : 2770-2776.

Autor/es:Zhao, W-P (a)
Zhang, W (b)

institución:Zhao, W-P (a)
Zhang, W (b)

Formato:Informe impreso

Idioma:Inglés

País de fuente:Italia

Sitio web:http://dx.doi.org/10.26355/eurrev_202404_35905

The global impact of SARS-CoV-2 variant BA.2.86: a comprehensive analysis with the latest developments and transmission trends - an epidemiological study.

Fuente:European Review For Medical and Pharmacological Sciences

Extracto: The SARS-CoV-2, novel variant BA.2.86, spread over six continents and 89 countries and affected 19,532 people worldwide. The disease is more prevalent in the United Kingdom, United States of America, and European countries. The detection of the disease in multiple continents and countries suggests some degree of transmissibility. Global health authorities need to rethink their policies and implement strict strategies to eradicate emerging variants and minimize the global disease burden.

Cita:Eur Rev Med Pharmacol Sci 2024 Apr; 28 (7) : 2969-2975.

Autor/es:Meo, S A (a)
Meo, A S (b)

institución:Meo, S A (a)
Meo, A S (b)

Formato:Informe impreso

Idioma:Inglés

País de fuente:Italia

Sitio web:http://dx.doi.org/10.26355/eurrev_202404_35928

Understanding How Clinicians Personalize Fluid and Vasopressor Decisions in Early Sepsis Management.

Understanding How Clinicians Personalize Fluid and Vasopressor Decisions in Early Sepsis Management.

Fuente:Jama Network Open

Extracto: AND RELEVANCE: These findings suggest that fluid volume received is the predominant factor associated with ongoing fluid and vasopressor decisions, outweighing many other clinical factors. Peripheral vasopressor use is common. Future studies aimed at personalizing resuscitation must account for fluid volumes and should incorporate specific tools to help clinicians personalize resuscitation.

Cita:JAMA Netw Open 2024 Apr 1; 7 (4) : e247480.

Autor/es:Munroe, Elizabeth S (a)
Weinstein, Julien (b)

institución:(a) Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of Michigan, Ann Arbor.
(b) Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of Michigan, Ann Arbor.

Conflicto:Conflict of Interest Disclosures: Dr Gershengorn reported receiving personal fees from Gilead Sciences and the American College of Chest Physicians; serving on a COVID-19 therapeutics advisory panel; and working as an editor for the CHEST Critical Care journal of the American College of Chest Physicians outside the submitted work. Dr Seelye reported receiving grants from the Agency for Healthcare Research... and Quality (AHRQ), VA Health Services Research & Development Services (VA HSR&D), and the Department of Defense outside the submitted work. Dr Sjoding reported having a patent for Computer Vision Technologies for Rapid Detection of Disease that is licensed to Airstrip but not currently active. Dr Prescott reported receiving grants from AHRQ, VA HSR&D, National Institutes of Health, and National Heart, Lung, and Blood Institute; personal fees from the Centers for Disease Control and Prevention and Blue Cross Blue Shield of Michigan; and serving as a developer of the Surviving Sepsis Campaign guidelines for the Society of Critical Care Medicine outside the submitted work. No other disclosures were reported.

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1001/jamanetworkopen.2024.7480

Asthma medication adherence, control, and psychological symptoms: a cross-sectional study.

Asthma medication adherence, control, and psychological symptoms: a cross-sectional study.

Fuente:Bmc Pulmonary Medicine

Extracto: The high prevalence of uncontrolled asthma symptoms and poor adherence to inhalers and their impact on anxiety and depression levels among patients with asthma point to the need for early screening for psychological symptoms and recognition of nonadherence as part of asthma assessment and management plan in primary care in Saudi Arabia to avoid further worsening of asthma symptoms. Further studies are needed to explore the effectiveness of specific psychoeducational interventions and investigate the long-term impact of early psychological symptom detection on asthma outcomes.

Claves:Adherence to controller therapies, Adherence to inhaler, Anxiety, Asthma, Asthma control, Depression

Cita:BMC Pulm Med 2024 Apr 19; 24 (1) : 189.

Autor/es:Alqarni, Abdullah A (a)
Aldhahir, Abdulelah M (b)

institución:(a) Department of Respiratory Therapy, Faculty of Medical Rehabilitation Sciences, King Abdulaziz University, Jeddah, Saudi Arabia. aaalqarni1@kau.edu.sa.
(b) Respiratory Therapy Unit, King Abdulaziz University Hospital, Jeddah, Saudi Arabia. aaalqarni1@kau.edu.sa.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12890-024-02995-x

MST1/2 exerts a pivotal role in inducing neuroinflammation and Coxsackievirus-A10 replication by interacting with innate immunity.

MST1/2 exerts a pivotal role in inducing neuroinflammation and Coxsackievirus-A10 replication by interacting with innate immunity.

Fuente:Virology Journal

Extracto: Overall, these data obviously pointed out that CV-A10 accelerated the formation of neuroinflammation by the effect of the Hippo pathway on the PRRs-mediated pathway, which delineates a negative immunoregulatory role for MST1/2 in CV-A10 infection and the potential for this pathway to be pharmacologically targeted to treat CV-A10.

Claves:Coxsackievirus-A10 (CV-A10), Hand, foot and mouth disease (HFMD), Hippo signaling pathway, Mammalian Ste20-like kinases 1/2 (MST1/2), Neuroinflammation

Cita:Virol J 2024 Apr 19; 21 (1) : 89.

Autor/es:Hu, Yajie (a)
Zhong, Minigmei (b)

institución:(a) Department of Respiratory Medicine, The First People's Hospital of Yunnan Province, Kunming, China.
(b) The Affiliated Hospital of Kunming University of Science and Technology, Kunming, China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12985-024-02355-5

Suboptimal peak inspiratory flow rate: a noticeable risk factor for inhaler concordance in patients with chronic airway diseases.

Suboptimal peak inspiratory flow rate: a noticeable risk factor for inhaler concordance in patients with chronic airway diseases.

Fuente:Bmj Open Respiratory Research

Extracto: Inhaler concordance was low, and suboptimal PIFR was a risk factor for poor concordance among Chinese patients with chronic airway diseases. In addition, current inhalation devices may not be suitable, and PIFR reassessment should be considered for patients with COPD during exacerbation. TRIAL REGISTRATION NUMBER: The study was registered in chictr.org.cn (ChiCTR2100052527) on 31 October 2021.

Claves:Asthma, Asthma Epidemiology, Asthma Pharmacology, COPD Pharmacology, COPD epidemiology, Inhaler devices, Pulmonary Disease, Chronic Obstructive

Cita:BMJ Open Respir Res 2024 Apr 19; 11 (1)

Autor/es:Meng, Weiwei (a)
Xiong, Ruoyan (b)

institución:(a) Department of Pulmonary and Critical Care Medicine, The Second Xiangya Hospital of Central South University, Changsha, Hunan, China.
(b) Research Unit of Respiratory Disease, Central South University, Changsha, Hunan, China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1136/bmjresp-2023-001981

Impact of an ICU bed capacity optimisation method on the average length of stay and average cost of hospitalisation following implementation of China's open policy with respect to COVID-19: a difference-in-differences analysis based on information management system data from a tertiary hospital in southwest China.

Impact of an ICU bed capacity optimisation method on the average length of stay and average cost of hospitalisation following implementation of China's open policy with respect to COVID-19: a difference-in-differences analysis based on information management system data from a tertiary hospital in southwest China.

Fuente:Bmj Open

Extracto: This study corroborates a significant positive impact of ICU bed optimisation in mitigating the shortage of medical resources following an epidemic outbreak. The findings hold theoretical and practical implications for identifying effective emergency coordination strategies in managing hospital bed resources during sudden public health emergency events. These insights contribute to the advancement of resource management practices and the promotion of experiences in dealing with public health emergencies.

Claves:COVID-19, China, decision making, health economics, health policy

Cita:BMJ Open 2024 Apr 19; 14 (4) : e078069.

Autor/es:Zheng, Qingyan (a)
Zeng, Zhongyi (b)

institución:(a) School of Business, Sichuan Unversity, Chengdu, China.
(b) The Hong Kong Polytechnic University, Hong Kong, China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1136/bmjopen-2023-078069

Bacterial interactome disturbance in chronic obstructive pulmonary disease clinical stability and exacerbations.

Bacterial interactome disturbance in chronic obstructive pulmonary disease clinical stability and exacerbations.

Fuente:Respiratory Research

Extracto: Bacterial interactome disturbance characterized by reduced antagonistic interactions, rather than change in pathogen abundance or diversity, is a reproducible feature of airway dysbiosis in COPD clinical stability and exacerbations, which suggests that we may target interactome rather than pathogen alone for disease treatment.

Claves:Airway dysbiosis, Antagonistic interaction, Chronic obstructive pulmonary disease, Exacerbation, Microbial interactome

Cita:Respir Res 2024 Apr 20; 25 (1) : 173.

Autor/es:Xiao, Wei (a)
Chen, Yi-Long (b)

institución:(a) Division of Pulmonary Medicine, Department of Internal Medicine, Institute of Integrated Traditional Chinese and Western Medicine, West China Hospital of Sichuan University, No. 37, Guoxue Lane, Wuhou District, Chengdu, 610041, China.
(b) Divison of Pulmonary diseases, State Key Laboratory of Biotherapy, West China Hospital of Sichuan University, Chengdu, China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12931-024-02802-5