DIAGNOSTICO DIFERENCIAL ENTRE HIPOGONADISMO HIPOGONADOTROFICO Y RETRASO PUBERAL SIMPLE EN VARONES CON NIVELES BASALES DE FSH





DIAGNOSTICO DIFERENCIAL ENTRE HIPOGONADISMO HIPOGONADOTROFICO Y RETRASO PUBERAL SIMPLE EN VARONES CON NIVELES BASALES DE FSH

(especial para SIIC © Derechos reservados)
Niveles basales de FSH < 1.2 UI/l confirman el diagnóstico de hipogonadismo hipogonadotrófico, sin necesidad de otra prueba diagnóstica, en varones con pubertad ausente o incompleta. En casos de niveles de FSH > 1.2 UI/l, el valor pico de FSH y LH luego de una infusión de GnRH tiene alta exactitud diagnóstica.
Autor:
Rodolfo A. Rey
Columnista Experto de SIIC

Institución:
Hospital de Niños Ricardo Gutiérrez


Artículos publicados por Rodolfo A. Rey
Coautor
Rodolfo A. Rey* 
Médico, Hospital de Niños Ricardo Gutiérrez, Buenos Aires, Argentina*
Aprobación
9 de Noviembre, 2010
Primera edición
15 de Diciembre, 2010
Segunda edición, ampliada y corregida
7 de Junio, 2021

Artículo completo

(castellano)
Extensión:  +/-2.9 páginas impresas en papel A4
Exclusivo para suscriptores/assinantes

Clasificación en siicsalud
Artículos originales > Expertos de Iberoamérica >
página   www.siicsalud.com/des/expertocompleto.php/

Especialidades
Principal: Endocrinología y Metabolismo, Pediatría
Relacionadas: Diagnóstico por Laboratorio, Medicina Familiar, Medicina Interna, Medicina Reproductiva



Comprar este artículo
Extensión: 2.9 páginas impresas en papel A4

file05.gif (1491 bytes) Artículos seleccionados para su compra



Enviar correspondencia a:
Rodolfo A. Rey, Centro de Investigaciones Endocrinológicas Hospital de Niños R. Gutiérrez , C1425EFD, Gallo 1330, Buenos Aires, Argentina
Bibliografía del artículo
1. Marshall WA, Tanner JM. Variations in the pattern of pubertal changes in boys. Arch Dis Child 45:13-23, 1970.
2. Lee PA. Normal ages of pubertal events among American males and females. J Adolesc Health Care 1:26-29, 1980.
3. Sedlmeyer IL, Palmert MR. Delayed puberty: analysis of a large case series from an academic center. J Clin Endocrinol Metab 87:1613-1620, 2002.
4. Grinspon RP, Rey RA. Anti-Müllerian hormone and Sertoli cell function in paediatric male hypogonadism. Horm Res Paediatr 73:81-92, 2010.
5. Sequera AM, Fideleff HL, Boquete HR, Pujol AB, Suárez MG, Ruibal GF. Basal ultrasensitive LH assay: a useful tool in the early diagnosis of male pubertal delay? J Pediatr Endocrinol Metab 15:589-596, 2002.
6. Odink RJ, Schoemaker J, Schoute E, Herdes E, Delemarre-Van de Waal HA. Predictive value of serum follicle-stimulating hormone levels in the differentiation between hypogonadotropic hypogonadism and constitutional delay of puberty. Horm Res 49:279-287, 1988.
7. Zamboni G, Antoniazzi F, Tato L. Use of the gonadotropin-releasing hormone agonist triptorelin in the diagnosis of delayed puberty in boys. J Pediatr 126:756-758, 1995.
8. Kauschansky A, Dickerman Z, Phillip M, Weintrob N, Strich D. Use of GnRH agonist and human chorionic gonadotrophin tests for differentiating constitutional delayed puberty from gonadotrophin deficiency in boys. Clin Endocrinol (Oxf) 56:603-607, 2002.
9. Street ME, Bandello MA, Terzi C, Ibanez L, Ghizzoni L, Volta C, Tripodi C, Virdis R. Leuteinizing hormone responses to leuprolide acetate discriminate between hypogonadotropic hypogonadism and constitutional delay of puberty. Fertil Steril 77:555-560, 2002.
10. Wilson DA, Hofman PL, Miles HL, Unwin KE, McGrail CE, Cutfield WS. Evaluation of the buserelin stimulation test in diagnosing gonadotropin deficiency in males with delayed puberty. J Pediatr 148:89-94, 2006.
11. Ibáñez L, Potau N, Zampolli M, Virdis R, Gussinye M, Carrascosa A, Saenger P, Vicens-Calvet E. Use of leuprolide acetate response patterns in the early diagnosis of pubertal disorders: comparison with the gonadotropin-releasing hormone test. J Clin Endocrinol Metab 78:30-35, 1994.
12. Martin MM, Martin AL. Constitutional delayed puberty in males and hypogonadotropic hypogonadism: a reliable and cost-effective approach to differential diagnosis. J Pediatr Endocrinol Metab 18:909-916, 2005.
13. Degros V, Cortet-Rudelli C, Soudan B, Dewailly D. The human chorionic gonadotropin test is more powerful than the gonadotropin-releasing hormone agonist test to discriminate male isolated hypogonadotropic hypogonadism from constitutional delayed puberty. Eur J Endocrinol 149:23-29, 2003.
14. Zevenhuijzen H, Kelnar CJ, Crofton PM. Diagnostic utility of a low-dose gonadotropin-releasing hormone test in the context of puberty disorders. Horm Res 62:168-176, 2004.
15. Fideleff HL, Boquete H, Saskyn N, Holland M. Evaluation of the gonadotropin and prolactin axis by LH-RH infusion and chlorpromazine test on hypogonadotropic hypogonadism and male delayed puberty. J Pediatr Endocrinol Metab 5:149-153, 1992.
16. Smals AG, Hermus AR, Boers GH, Pieters GF, Benraad TJ, Kloppenborg PW. Predictive value of luteinizing hormone releasing hormone (LHRH) bolus testing before and after 36-hour pulsatile LHRH administration in the differential diagnosis of constitutional delay of puberty and male hypogonadotropic hypogonadism. J Clin Endocrinol Metab 78:602-608, 1994.
17. Bossuyt PM, Reitsma JB, Bruns DE, Gatsonis CA, Glasziou PP, Irwig LM, Moher D, Rennie D, De Vet HC, Lijmer JG. The STARD statement for reporting studies of diagnostic accuracy: explanation and elaboration. Clin Chem 49:7-18, 2003.
18. Ropelato MG, Escobar ME, Gottlieb S, Bergadá C. Gonadotropin secretion in prepubertal normal and agonadal children evaluated by ultrasensitive time-resolved immunofluorometric assays. Horm Res 48:164-172, 1997.
19. Lanes R, Gunczler P, Osuna JA, Palacios A, Carrillo E, Ramirez X, Garcia C, Paoli M, Villaroel O. Effectiveness and limitations of the use of the gonadotropin-releasing hormone agonist leuprolide acetate in the diagnosis of delayed puberty in males. Horm Res 48:1-4, 1997.
20. Partsch CJ, Hermanussen M, Sippell WG. Differentiation of male hypogonadotropic hypogonadism and constitutional delay of puberty by pulsatile administration of gonadotropin-releasing hormone. J Clin Endocrinol Metab 60:1196-1203, 1985.
21. Kologlu S, Uysal AR, Kologlu LB. The differentiation between constitutional delayed puberty and hypogonadotropic hypogonadism: experience with three newly devised methods. Endocrinologie 26:3-15, 1988.
22. Segal TY, Mehta A, Anazodo A, Hindmarsh PC, Dattani MT. Role of gonadotropin-releasing hormone and human chorionic gonadotropin stimulation tests in differentiating patients with hypogonadotropic hypogonadism from those with constitutional delay of growth and puberty. J Clin Endocrinol Metab 94:780-785, 2009.
23. Mainieri AS, Viera JG, Elnecave RH. Response of the free alpha-subunit to GnRH distinguishes individuals with functional from those with permanent hypogonadotropic hypogonadism. Horm Res 50:212-216, 1998.
24. Mainieri AS, Elnecave RH. Usefulness of the free alpha-subunit to diagnose hypogonadotropic hypogonadism. Clin Endocrinol (Oxf) 59:307-313, 2003.
25. Haavisto AM, Dunkel L, Pettersson K, Huhtaniemi I. LH measurements by in vitro bioassay and a highly sensitive immunofluorometric assay improve the distinction between boys with constitutional delay of puberty and hypogonadotropic hypogonadism. Pediatr Res 27:211-214, 1990.
26. Raivio T, Falardeau J, Dwyer A, Quinton R, Hayes FJ, Hughes VA, Cole LW, Pearce SH, Lee H, Boepple P, Crowley WF Jr, Pitteloud N. Reversal of idiopathic hypogonadotropic hypogonadism. N Engl J Med 357:863-873, 2007.

Título español
 Bibliografía
 Artículo completo
(exclusivo a suscriptores)
 Autoevaluación
  Tema principal en SIIC Data Bases
 Especialidades

  English title
  Abstract
  Key words
Full text
(exclusivo a suscriptores)


Autor 
Artículos
Correspondencia
Patrocinio y reconocimiento
Imprimir esta página
 
 
 
 
 
 
 
 
 
 
 
 
Está expresamente prohibida la redistribución y la redifusión de todo o parte de los contenidos de la Sociedad Iberoamericana de Información Científica (SIIC) S.A. sin previo y expreso consentimiento de SIIC.
ua31618