Association of obstructive sleep apnea symptoms with all-cause mortality and cause-specific mortality in adults with or without diabetes

Association of obstructive sleep apnea symptoms with all-cause mortality and cause-specific mortality in adults with or without diabetes

Fuente:Journal of Diabetes

Tipo de trabajo:Estudio de cohortes

Extracto: The relationship between OSAS and mortality differed among participants with or without diabetes. Individualized clinical treatment plans should be developed in clinical practice to reduce the risk of death for patients with different metabolic conditions.

Claves:NHANES, diabetes, mortality, obstructive sleep apnea syndrome

Cita:J Diabetes 2024 Apr; 16 (4) : e13538.

Autor/es:Zhang, Qian (a)
Zhang, Qi (b)

institución:(a) Department of General Practice, Affiliated Hospital of Weifang Medical University, Weifang, China.
(b) Department of Endocrinology and Metabolism, Affiliated Hospital of Weifang Medical University, Weifang, China.

Formato:Informe impreso

Idioma:Inglés

País de fuente:Australia

Sitio web:http://dx.doi.org/10.1111/1753-0407.13538

Association of advanced glycation end products with ear lobe crease: A cross-sectional study.

Fuente:Journal of Diabetes

Extracto: ELC is associated with coronary heart disease, and the SAF-AGE has a potential role in ELC development in elder people.

Claves:advanced glycation end products, cardiovascular disease, ear lobe crease, type 2 diabetes

Cita:J Diabetes 2024 Apr; 16 (4) : e13548.

Autor/es:Wang, Yuepeng (a)
Xin, Yu (b)

institución:(a) Department of Endocrinology, The First Medical Center of Chinese PLA General Hospital, Beijing, China.
(b) School of Medicine, Nankai University, Tianjin, China.

Formato:Informe impreso

Idioma:Inglés

País de fuente:Australia

Sitio web:http://dx.doi.org/10.1111/1753-0407.13548

Traditional and emerging strategies using hepatocytes for pancreatic regenerative medicine.

Fuente:Journal of Diabetes

Extracto: In addition, clustered regularly interspaced short palindromic repeats (CRISPR)/Cas9 gene editing technology has brought new opportunities and challenges to the development of organoid technology.

Claves:CRISPR/Cas9, epatocytes, organoids, regenerative medicine

Cita:J Diabetes 2024 Apr; 16 (4) : e13545.

Autor/es:Liu, Shuang (a)
Zhang, YuYing (b)

institución:(a) Department of Metabolism and Endocrinology, the Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, China.
(b) Department of Metabolism and Endocrinology, the Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe impreso

Idioma:Inglés

País de fuente:Australia

Sitio web:http://dx.doi.org/10.1111/1753-0407.13545

Advanced multifunctional hydrogels for diabetic foot ulcer healing: Active substances and biological functions.

Fuente:Journal of Diabetes

Tipo de trabajo:Revisión

Extracto: Hydrogels were classified into carrier hydrogels and self-functioning hydrogels in this review. Besides, the functions and components of existing hydrogels were clarified to provide assistance for future researches and clinical applications.

Claves:biological functions, classification, diabetic foot ulcer, hydrogels, pathogenesis

Cita:J Diabetes 2024 Apr; 16 (4) : e13537.

Autor/es:Li, Yuetong (a)
Leng, Yuxin (b)

institución:(a) Department of Endocrinology, The Eighth Affiliated Hospital, Sun Yat-sen University, Shenzhen, China.
(b) Department of Critical Care Medicine, Peking University Third Hospital, Beijing, China.

Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Formato:Informe impreso

Idioma:Inglés

País de fuente:Australia

Sitio web:http://dx.doi.org/10.1111/1753-0407.13537

Comparing Equil patch versus traditional catheter insulin pump in type 2 diabetes using continuous glucose monitoring metrics and profiles.

Fuente:Journal of Diabetes

Tipo de trabajo:Estudio clínico

Extracto: The Equil patch insulin pump was similar to the traditional MMT-712 insulin pump in terms of glycemic control. Equil patch insulin pump is a reliable tool for glycemic management of diabetes mellitus.

Claves:T2DM, continuous glucose monitoring, patch insulin pump

Cita:J Diabetes 2024 Apr; 16 (4) : e13536.

Autor/es:Li, Yu-Jiao (a)
Shao, Zi-Yue (b)

institución:(a) Department of Endocrinology, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.
(b) Department of Endocrinology, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.

Formato:Informe impreso

Idioma:Inglés

País de fuente:Australia

Sitio web:http://dx.doi.org/10.1111/1753-0407.13536

Novel T cell exhaustion gene signature to predict prognosis and immunotherapy response in thyroid carcinoma from integrated RNA-sequencing analysis.

Novel T cell exhaustion gene signature to predict prognosis and immunotherapy response in thyroid carcinoma from integrated RNA-sequencing analysis.

Fuente:Scientific Reports

Extracto: Therapeutic strategies that target SPP1(+) macrophages, CD14(+) monocytes, and the SPP1-CD44 and MIF-CD74 axes may potentially improve the prognosis and amplify the immunotherapy response in THCA patients.

Claves:Gene signature, Immunotherapy, Single-cell RNA-sequencing, T cell exhaustion, Thyroid carcinoma, Tumor-associated macrophage

Cita:Sci Rep 2024 Apr 10; 14 (1) : 8375.

Autor/es:Li, Yang (a)
Wang, Zhen (b)

institución:(a) Department of Endocrinology, First Affiliated Hospital of Anhui Medical University, Hefei, China.
(b) Department of Endocrinology, First Affiliated Hospital of Anhui Medical University, Hefei, China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1038/s41598-024-58419-7

Cannabidiol exerts multitarget immunomodulatory effects on PBMCs from individuals with psoriasis vulgaris.

Cannabidiol exerts multitarget immunomodulatory effects on PBMCs from individuals with psoriasis vulgaris.

Fuente:Frontiers in Immunology

Extracto: These data uncover new potential immunomodulatory properties of this cannabinoid suggesting a possible therapeutic action in the treatment of multiple inflammatory skin diseases.

Claves:CBD, dendritic cells, macrophage, monocyte, natural killer, psoriasis

Cita:Front Immunol 2024; 15 : 1373435.

Autor/es:Pagano, Cristina (a)
Ciaglia, Elena (b)

institución:(a) Department of Molecular Medicine and Medical Biotechnology, University of Naples Federico II, Naples, Italy.
(b) Department of Medicine, Surgery and Dentistry "Scuola Medica Salernitana", University of Salerno, Baronissi, Italy.

Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3389/fimmu.2024.1373435

The fatal contribution of serine protease-related genetic variants to COVID-19 outcomes.

Fuente:Frontiers in Immunology

Extracto: Additionally, rs2227692 SERPINE1 could participate in hypercoagulable conditions in critical COVID-19 patients, and this genetic variant could contribute to the identification of new pharmacological targets and treatment strategies to block the inhibition of TMPRSS2 entry into SARS-CoV-2.

Claves:COVID-19, Polymorphism, SARS-CoV-2, SERPINE1, TMPRSS2

Cita:Front Immunol 2024; 15 : 1335963.

Autor/es:Martínez-Gómez, Laura Edith (a)
Martinez-Armenta, Carlos (b)

institución:(a) Laboratorio de Gerociencias, Dirección General, Departamento de Reconstrucción Articular, Laboratorio Facilitador, Instituto Nacional de Rehabilitación Luis Guillermo Ibarra Ibarra, Secretaría de Salud, Mexico City, Mexico.
(b) Laboratorio de Gerociencias, Dirección General, Departamento de Reconstrucción Articular, Laboratorio Facilitador, Instituto Nacional de Rehabilitación Luis Guillermo Ibarra Ibarra, Secretaría de Salud, Mexico City, Mexico.

Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. The author(s) declared that they were an editorial board member of Frontiers, at the time of submission. This had no impact on the peer review process and the final decision.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3389/fimmu.2024.1335963

Five percent weight loss is a significant 1-year predictor and an optimal 5-year cut-off for reducing the number of obesity-related cardiovascular disease risk components: the Japan Obesity and Metabolic Syndrome Study.

Five percent weight loss is a significant 1-year predictor and an optimal 5-year cut-off for reducing the number of obesity-related cardiovascular disease risk components: the Japan Obesity and Metabolic Syndrome Study.

Fuente:Frontiers in Endocrinology

Extracto: A weight loss of ≥5.0% at 1 year and ≥7.5% at 5 years could reduce the number of obesity-related CVD risk components in patients with obesity.

Claves:5-year follow-up, cohort study, metabolic syndrome, obesity, weight loss

Cita:Front Endocrinol (Lausanne) 2024; 15 : 1343153.

Autor/es:Yamakage, Hajime (a)
Jo, Takaaki (b)

institución:(a) Department of Endocrinology, Metabolism, and Hypertension Research, Clinical Research Institute, NHO Kyoto Medical Center, Kyoto, Japan.
(b) Department of General Internal Medicine, Fushimi Momoyama General Hospital, Kyoto, Japan.

Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. The author(s) declared that they were an editorial board member of Frontiers, at the time of submission. This had no impact on the peer review process and the final decision MT is an... Editorial Board Member of this journal but was not involved in the peer-review process nor had access to any information regarding its peer-review.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3389/fendo.2024.1343153

The association between Chinese visceral adiposity index and cardiometabolic multimorbidity among Chinese middle-aged and older adults

Fuente:Frontiers in Endocrinology

Tipo de trabajo:Estudio de cohortes

Extracto: The CVAI is a valid biomarker with good predictive capability for cardiometabolic multimorbidity and can be used by primary healthcare organizations in the future for early warning, prevention, and intervention with regard to cardiometabolic multimorbidity.

Claves:Chinese visceral adiposity index, cardiometabolic multimorbidity, cohort study, diabetes, heart disease, middle-aged and older adults, stroke

Cita:Front Endocrinol (Lausanne) 2024; 15 : 1381949.

Autor/es:Ye, Xiaomei (a)
Zhang, Guangru (b)

institución:(a) Department of Endocrinology, Qingpu Branch of Zhongshan Hospital Affiliated to Fudan University, Shanghai, China.
(b) Department of General Practice, Community Health Service Center Xiayang Street, Shanghai, China.

Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3389/fendo.2024.1381949

Analysis of clinical evidence on traditional Chinese medicine for the treatment of diabetic nephropathy

Fuente:Frontiers in Endocrinology

Tipo de trabajo:Revisión

Extracto: DN represents a significant health challenge, particularly for the elderly, with TCM showing promise in symptom alleviation and renal protection. Yet, the field is marred by research inconsistencies and methodological shortcomings. Future investigations should prioritize the development of standardized outcome sets tailored to DN, carefully select evaluation indicators that reflect TCM's unique intervention strategies, and aim to improve the robustness of clinical evidence. Emphasizing TCM's foundational theories while incorporating advanced scientific technologies will be essential for innovating research methodologies and uncovering the mechanisms underlying TCM's efficacy in DN management.

Claves:diabetes mellitus, diabetic complications, diabetic nephropathy, evidence mapping, evidence-based analysis, randomized controlled trials, systematic review, traditional Chinese medicine

Cita:Front Endocrinol (Lausanne) 2024; 15 : 1324782.

Autor/es:Gao, Yating (a)
Li, Zhenghong (b)

institución:(a) Institute of Endocrinology, Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
(b) Graduate School, Beijing University of Chinese Medicine, Beijing, China.

Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3389/fendo.2024.1324782

Feature selection and risk prediction for diabetic patients with ketoacidosis based on MIMIC-IV.

Fuente:Frontiers in Endocrinology

Extracto: The study found that hematocrit, hemoglobin, anion gap, age, and Charlson comorbidity index are closely associated with ketoacidosis. In clinical practice, these five baseline characteristics should be given with the special attention to achieve early detection and treatment, thus reducing the incidence of the disease.

Claves:MIMIC-IV, diabetes mellitus, diabetic ketoacidosis, feature selection, risk prediction

Cita:Front Endocrinol (Lausanne) 2024; 15 : 1344277.

Autor/es:Liu, Yang (a)
Mo, Wei (b)

institución:(a) Endocrinology, The Fifth Clinical College of Guangzhou University of Chinese Medicine, Guangzhou, China.
(b) Endocrinology, Guangdong Provincial Second Hospital of Traditional Chinese Medicine, Guangzhou, China.

Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3389/fendo.2024.1344277

Prevalence of vitamin D insufficiency in early pregnancies- a Singapore study.

Prevalence of vitamin D insufficiency in early pregnancies- a Singapore study.

Fuente:Plos One

Extracto: We also hope to evaluate the association of low vitamin D levels with obstetric or neonatal complications further understanding its implications.

Cita:PLoS One 2024; 19 (4) : e0300063.

Autor/es:Amelia, Chua Zu'Er (a)
Gwan, Chan Hiu (b)

institución:(a) Department of Obstetrics and Gynaecology, KK Women's and Children's Hospital, Singapore, Singapore.
(b) Obstetrics and Gynaecology Academic Clinical Programme (OBGYN ACP), SingHealth Services, Singapore, Singapore.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1371/journal.pone.0300063

The high-density lipoprotein cholesterol (HDL-C)-concentration-dependent association between anti-inflammatory capacity and sepsis: A single-center cross-sectional study.

Fuente:Plos One

Extracto: ApoB-depleted plasma's anti-inflammatory capacity is reduced in sepsis patients and this association depends of HDL-C concentration. In sepsis patients, this capacity correlates with disease severity and inflammatory markers. These findings explain the prognostic role of the HDL-C level in sepsis and indirectly support the rationale for targeting HDL-C as sepsis treatment.

Cita:PLoS One 2024; 19 (4) : e0296863.

Autor/es:Chen, Kai-Lee (a)
Chou, Ruey-Hsing (b)

institución:(a) Institute of Clinical Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.
(b) Institute of Clinical Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1371/journal.pone.0296863

Low-dose aspirin for the prevention of preterm birth in nulliparous women

Low-dose aspirin for the prevention of preterm birth in nulliparous women

Fuente:Bmc Pregnancy and Childbirth

Tipo de trabajo:Revisión sistemática

Extracto: Low-dose aspirin might reduce the risk of preterm birth at less than 34 weeks of gestation in nulliparous women. The use of low-dose aspirin in nulliparous women increased the risk of postpartum hemorrhage and might increase the risk of placental abruption and cesarean section.

Claves:Aspirin, Preterm birth, Systematic review, meta-analysis

Cita:BMC Pregnancy Childbirth 2024 Apr 11; 24 (1) : 260.

Autor/es:Yan, Xin (a)
Zheng, Wei (b)

institución:(a) Division of Endocrinology and Metabolism, Department of Obstetrics, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing Maternal and Child Health Care Hospital, No.251, Yaojiayuan Road, Chaoyang District, Beijing, 100026, China.
(b) Division of Endocrinology and Metabolism, Department of Obstetrics, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing Maternal and Child Health Care Hospital, No.251, Yaojiayuan Road, Chaoyang District, Beijing, 100026, China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12884-024-06413-2

Clinical spectrum, over 12-year follow-up and experience of SGLT2 inhibitors treatment on patients with glycogen storage disease type Ib: a single-center retrospective study.

Clinical spectrum, over 12-year follow-up and experience of SGLT2 inhibitors treatment on patients with glycogen storage disease type Ib: a single-center retrospective study.

Fuente:Orphanet Journal of Rare Diseases

Extracto: Empagliflozin treatment for pediatric GSD Ib patients is efficient and safe. Increase of urine glucose is a signal for pharmaceutical effect, however attention to urinary infection and hypoglycemia is suggested.

Claves:Empagliflozin, GSD Ib, Glycogen storage disease type Ib, Pediatric, slc37a4

Cita:Orphanet J Rare Dis 2024 Apr 11; 19 (1) : 155.

Autor/es:Shao, Yong-Xian (a)
Liang, Cui-Li (b)

institución:(a) Department of Pediatric Endocrinology and Genetic Metabolism, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, 510623, Guangzhou, China.
(b) Department of Pediatric Endocrinology and Genetic Metabolism, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, 510623, Guangzhou, China.

Conflicto:All authors declare no conflict of interest.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s13023-024-03137-6

Increased interleukin-9 and Th9 cells in patients with refractory Graves' disease and interleukin-9 polymorphisms are associated with autoimmune thyroid diseases.

Increased interleukin-9 and Th9 cells in patients with refractory Graves' disease and interleukin-9 polymorphisms are associated with autoimmune thyroid diseases.

Fuente:Frontiers in Immunology

Extracto: DISCUSSION: Our results reveal that Th9 cells may exert a pivotal role in the pathogenesis and progression of refractory GD and HT, and IL-9 holds promise as a novel therapeutic target for the management of AITDs.

Claves:Hashimoto’s thyroiditis, IL-9, Th9 cells, polymorphisms, refractory Graves’ disease

Cita:Front Immunol 2024; 15 : 1341749.

Autor/es:Yao, Qiuming (a)
Song, Zhenyu (b)

institución:(a) Department of Endocrinology, Shanghai University of Medicine & Health Sciences Affiliated Zhoupu Hospital, Shanghai, China.
(b) Department of Tumor Interventional Oncology, School of Medicine, Renji Hospital, Shanghai Jiaotong University, Shanghai, China.

Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3389/fimmu.2024.1341749

Association of circulating inflammatory proteins with type 2 diabetes mellitus and its complications: a bidirectional Mendelian randomization study.

Association of circulating inflammatory proteins with type 2 diabetes mellitus and its complications: a bidirectional Mendelian randomization study.

Fuente:Frontiers in Endocrinology

Tipo de trabajo:Metanálisis

Extracto: This study determined four circulating inflammatory proteins that affected the occurrence of T2D, providing opportunities for the early prevention and innovative therapy of type 2 diabetes and its complications.

Claves:Mendelian randomization, bidirectional, circulating inflammatory proteins, meta-analysis, type 2 diabetes mellitus

Cita:Front Endocrinol (Lausanne) 2024; 15 : 1358311.

Autor/es:Liang, Ying-Chao (a)
Jia, Ming-Jie (b)

institución:(a) The Fourth Clinical Medical College of Guangzhou University of Chinese Medicine, Shenzhen, Guangdong, China.
(b) The Fourth Clinical Medical College of Guangzhou University of Chinese Medicine, Shenzhen, Guangdong, China.

Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3389/fendo.2024.1358311

The triglyceride glucose index as a sensitive predictor for the risk of MACCEs in patients with diabetic foot ulcers

The triglyceride glucose index as a sensitive predictor for the risk of MACCEs in patients with diabetic foot ulcers

Fuente:International Wound Journal

Tipo de trabajo:Estudio de cohortes

Extracto: Consequently, lowering the TyG index level aids in improving the prognosis of patients with DFUs.

Claves:diabetic foot ulcer, major adverse cardiovascular and cerebrovascular events, triglyceride glucose index

Cita:Int Wound J 2024 Apr; 21 (4) : e14874.

Autor/es:Wei, Rongyan (a)
Chen, Shangyu (b)

institución:(a) Department of Endocrinology and Metabolism, Guangxi Academy of Medical Sciences and the People's Hospital of Guangxi Zhuang Autonomous Region, Nanning, Guangxi, China.
(b) Department of Endocrinology and Metabolism, Guangxi Academy of Medical Sciences and the People's Hospital of Guangxi Zhuang Autonomous Region, Nanning, Guangxi, China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe impreso

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1111/iwj.14874

Integrated proteogenomic and metabolomic characterization of papillary thyroid cancer with different recurrence risks.

Integrated proteogenomic and metabolomic characterization of papillary thyroid cancer with different recurrence risks.

Fuente:Nature Communications

Extracto: This study can provide insights into the complex molecular characteristics of PTC recurrences and help promote early diagnosis and precision treatment of recurrent PTC.

Cita:Nat Commun 2024 Apr 12; 15 (1) : 3175.

Autor/es:Qu, Ning (a)
Chen, Di (b)

institución:(a) Department of Head and Neck Surgery, Fudan University Shanghai Cancer Center, Shanghai, China.
(b) Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1038/s41467-024-47581-1