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estructura de un estudio: especialidad, modalidad del estudio,
fuente, fechas de publicación y selección, definición de la fuente,
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Si bien la mayoría de los textos seleccionados corresponden a
artículos originales, revisiones y guías, los lectores también
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autores u otros textos precursores de debates o aclaratorios.
Sociedad Iberoamericana de Información Científica (SIIC) selects
complete quality-full texts which have been recently published in
renowned sources worldwide and are indexed by SIIC Data
Bases.
The increasing number of Open Access articles widens the reading offer
but, also, such myriad complicates the readers search of fundamental
articles. To facilitate this, SIIC biomedical professionals daily
consult a profuse amount of documents that will feed
Authorized Full Texts (TCA, Spanish acronym).
The citations of the AFT section link legally, authorized and free of
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their corresponding sources.
SIIC created, produced and handles the AFT software that deciphers
the various documentary fields that form part of the structure of a
study: specialty, study style, source, publication and selection
dates, source definition, query limitations, summary in Spanish,
etc.
While most of the selected texts belong to original articles,
reviews, and guidelines, readers will also find commentaries,
interviews, journalistic reports, letters to authors or other texts
that may lead to discussions or clarifications.
Oligogenic analysis across broad phenotypes of 46,XY differences in sex development associated with NR5A1/SF-1 variants: findings from the international SF1next study.
Oligogenic analysis across broad phenotypes of 46,XY differences in sex development associated with NR5A1/SF-1 variants: findings from the international SF1next study.
Fuente:Ebiomedicine
Extracto:
FUNDING: Swiss National Science Foundation and
Boveri Foundation Zurich.
Claves:46,XY DSD, Differences of sex development (DSD), Oligogenicity, Steroidogenic factor 1 (SF-1/NR5A1)
Cita:EBioMedicine 2025 Mar; 113 : 105624.
Autor/es:Kouri, Chrysanthi (a) Martinez de Lapiscina, Idoia (b)
institución:(a) Pediatric Endocrinology, Diabetology and Metabolism, Department of Pediatrics, Inselspital, Bern University Hospital, University of Bern, Bern 3010, Switzerland; Department for BioMedical Research, University of Bern, Bern 3008, Switzerland; Graduate School for Cellular and Biomedical Sciences, University of Bern, Bern 3012, Switzerland. (b) Pediatric Endocrinology, Diabetology and Metabolism, Department of Pediatrics, Inselspital, Bern University Hospital, University of Bern, Bern 3010, Switzerland; Department for BioMedical Research, University of Bern, Bern 3008, Switzerland; Research into the Genetics and Control of Diabetes and Other Endocrine Disorders, Biobizkaia Health Research Institute, Cruces University Hospital, Barakaldo 48903, Spain; CIBER de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Instituto de Salud Carlos III, Madrid 28029, Spain; CIBER de Enfermedades Raras (CIBERER), Instituto de Salud Carlos III, Madrid 28029, Spain; Endo-ERN, Amsterdam 1081 HV, the Netherlands.
Conflicto:Declaration of interests The SF1next study group was formed from the I-DSD research community (https://sdmregistries.org/) and related networks caring for rare patients with DSD. No conflict of interest has been reported from collaborating members.
Multiomics reveal key inflammatory drivers of severe obesity: IL4R, LILRA5, and OSM.
Multiomics reveal key inflammatory drivers of severe obesity: IL4R, LILRA5, and OSM.
Fuente:Cell Genomics
Extracto:
Our
findings furnish a molecular architecture of the severe obesity phenotype across
multiple molecular domains.
Claves:RNA-seq, adiposity, multi-omics, obesity, proteome, severe obesity, transcriptome, understudied population
Cita:Cell Genom 2025 Mar 12; 5 (3) : 100784.
Autor/es:Chen, Hung-Hsin (a) Highland, Heather M (b)
institución:(a) Department of Medicine, Division of Genetic Medicine, Vanderbilt University School of Medicine, Nashville, TN, USA; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, USA; Academia Sinica, Institute of Biomedical Sciences, Taipei, Taiwan. (b) Department of Epidemiology, Gillings School of Global Public Health, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Conflicto:Declaration of interests D.M.S. is currently employed by AstraZeneca; all contributions to this work occurred prior to employment at AstraZeneca. N.J.C. is on the advisory board of Cell Genomics.
A 58-Year-Old Man with a History of Autoimmune Thyroiditis Diagnosed with Mucosa-Associated Lymphoid Tissue Lymphoma and Papillary Carcinoma of the Thyroid.
A 58-Year-Old Man with a History of Autoimmune Thyroiditis Diagnosed with Mucosa-Associated Lymphoid Tissue Lymphoma and Papillary Carcinoma of the Thyroid.
Fuente:The American Journal of Case Reports
Extracto:
This report highlights
the association between Hashimoto's thyroiditis and thyroid MALT lymphoma,
presents a rare finding of coexistent PTC and lymphadenopathy of initially
unknown origin, and underscores the importance of histopathology in the diagnosis
of these conditions.
Cita:Am J Case Rep 2025 Mar 9; 26 : e946022.
Autor/es:Babaya, Naru (a) Yoshida, Sawa (b)
institución:(a) Department of Endocrinology, Metabolism and Diabetes, Kindai University Faculty of Medicine, Osaka-Sayama, Osaka, Japan. (b) Department of Endocrinology, Metabolism and Diabetes, Kindai University Faculty of Medicine, Osaka-Sayama, Osaka, Japan.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Autor/es:Weinstein, David A (a) Derks, Terry G (b)
institución:(a) Department of Pediatrics, University of Connecticut, Farmington, Connecticut, USA. (b) Section of Metabolic Diseases, Beatrix Children's Hospital, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
FGFR1 variation in the divergent settings of congenital hypopituitarism and pituitary tumours.
FGFR1 variation in the divergent settings of congenital hypopituitarism and pituitary tumours.
Fuente:Pituitary
Extracto:
Our results suggest that the FGFR1
D129A variant may be associated with pituitary tumorigenesis but the role of
other pituitary embryogenesis genes remains unclear. Additional independent
cohorts and functional studies are required.
Claves:FGFR1, Hypopituitarism, Next generation sequencing, Pituitary adenoma, Pituitary tumour
Cita:Pituitary 2025 Mar 10; 28 (2) : 39.
Autor/es:Orsmond, Andreas (a) Krishnan, Gayathri (b)
institución:(a) Garvan Institute of Medical Research, 384 Victoria St, Darlinghurst, NSW, 2010, Australia. (b) Garvan Institute of Medical Research, 384 Victoria St, Darlinghurst, NSW, 2010, Australia.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Cytokines and chemokines modulate the growth of pituitary adenoma/neuroendocrine tumors: preliminary results of a monocenter prospective pilot study.
Cytokines and chemokines modulate the growth of pituitary adenoma/neuroendocrine tumors: preliminary results of a monocenter prospective pilot study.
Fuente:Pituitary
Extracto:
Our preliminary results support that in PAs/PitNETs, the cytokines and chemokines
generate an immune network, that may contribute to regulating the cell
proliferation and pattern of growth.
Autor/es:Chiloiro, Sabrina (a) Mattogno, Pier Paolo (b)
institución:(a) Facoltà di Medicina e Chirurgia, Università Cattolica del Sacro Cuore, Rome, Italy. sabrina.chiloiro@unicatt.it. (b) Dipartimento di Endocrinologia, Diabetologia e Medicina Interna, Fondazione Policlinico Universitario A. Gemelli, Istituto di Ricovero e cura a carattere scientifico (IRCCS), Rome, Italy. sabrina.chiloiro@unicatt.it.
Conflicto:Declarations. Conflict of interest: SC, AB, AG, LDM have served as investigator for clinical trials funded by Novartis, Pfizer, Ipsen and Crinetics. SC and AB received grants from Pfizer. SC won the 2022 Arrigo Recordati Research Grant. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as...
a potential conflict of interest.
Effectiveness of a low-glycaemic-index formula on post-gastrectomy hypoglycaemia in patients with gastric cancer: randomized crossover study.
Effectiveness of a low-glycaemic-index formula on post-gastrectomy hypoglycaemia in patients with gastric cancer: randomized crossover study.
Fuente:Bjs Open
Tipo de trabajo:Estudio abierto
Extracto:
The
low-carbohydrate/high-monounsaturated fatty acid formula improved
post-gastrectomy night-time hypoglycaemia, but not daytime glycaemic variability
or hypoglycaemia. Thus, further investigation of nutritional optimization is
required. CLINICAL TRIAL REGISTRATION: Japan Registry of Clinical Trials, jRCT
https://jrct.niph.go.jp/, identifier jRCTs s051210200.
Cita:BJS Open 2025 Mar 4; 9 (2)
Autor/es:Kubota, Takeshi (a) Ohashi, Takuma (b)
institución:(a) Division of Digestive Surgery, Department of Surgery, Kyoto Prefectural University of Medicine, Kyoto, Japan. (b) Division of Digestive Surgery, Department of Surgery, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Enhancing patient-centered care: Evaluating quality of life in type 2 diabetes management.
Enhancing patient-centered care: Evaluating quality of life in type 2 diabetes management.
Fuente:Plos One
Extracto:
Patients with T2DM report
generally satisfactory QoL, with notable concerns in socio-economic and
health-related areas. Routine QoL assessments in clinical practice can improve
communication, aid in early complication detection, and enable timely
interventions to enhance patient outcomes.
Cita:PLoS One 2025; 20 (3) : e0319369.
Autor/es:Vlahovic, Branka (a) Jha, Vivek (b)
institución:(a) Metabolic Intensive Care Unit, Internal Medicine Clinic, Clinical Center of Montenegro, Podgorica, Montenegro. (b) Department of Endocrinology, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, Punjab, India.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Impact of hemoglobin level on the association between lipid metabolism and gestational diabetes mellitus: A retrospective study.
Impact of hemoglobin level on the association between lipid metabolism and gestational diabetes mellitus: A retrospective study.
Fuente:Medicine
Extracto:
Our findings
highlight HGB level as a potential novel marker for screening GDM risk in the
first trimester, particularly among women with dyslipidemia.
Cita:Medicine (Baltimore) 2025 Mar 7; 104 (10) : e41778.
Autor/es:Yang, Xinxin (a) Wang, Guangya (b)
institución:(a) Department of Endocrinology, Cangzhou Central Hospital, Cangzhou, China. (b) Department of Endocrinology, Cangzhou Central Hospital, Cangzhou, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Delayed slipped capital femoral epiphysis with hypothyroidism in children
Delayed slipped capital femoral epiphysis with hypothyroidism in children
Fuente:Medicine
Tipo de trabajo:Caso clínico
Extracto:
Early recognition and interdisciplinary management of both orthopedic and
endocrine aspects can optimize outcomes and prevent long-term complications,
emphasizing the value of a comprehensive diagnostic approach.
Cita:Medicine (Baltimore) 2025 Mar 7; 104 (10) : e41789.
Autor/es:Zhao, Qinggang (a) Hu, Xingxi (b)
institución:Zhao, Qinggang (a) Hu, Xingxi (b)
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Atlas of imprinted and allele-specific DNA methylation in the human body.
Atlas of imprinted and allele-specific DNA methylation in the human body.
Fuente:Nature Communications
Extracto:
The atlas provides a resource for studying allele-specific methylation and
regulatory mechanisms underlying imprinted expression in specific human cell
types.
Cita:Nat Commun 2025 Mar 11; 16 (1) : 2141.
Autor/es:Rosenski, Jonathan (a) Peretz, Ayelet (b)
institución:(a) School of Computer Science and Engineering, The Hebrew University of Jerusalem, Jerusalem, Israel. (b) Department of Developmental Biology and Cancer Research, Institute for Medical Research Israel-Canada, Hadassah Medical Center and Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem, Israel.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Autor/es:Batouty, Nihal M (a) Shokeir, Farah A (b)
institución:(a) Department of Diagnostic and Interventional Radiology, Faculty of Medicine, Mansoura University, 12 El-Gomhoreya street, 35112, Mansoura, Egypt. (b) Department of Diagnostic and Interventional Radiology, Faculty of Medicine, Mansoura University, 12 El-Gomhoreya street, 35112, Mansoura, Egypt.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Choroidal thickness as predictor of subclinical carotid atherosclerosis in adults with type 1 diabetes.
Choroidal thickness as predictor of subclinical carotid atherosclerosis in adults with type 1 diabetes.
Fuente:Scientific Reports
Extracto:
Integrating this measure in specialized clinical settings could help
identify individuals who may need additional cardiovascular assessments.
institución:(a) Department of Medicine, Division of Endocrinology, Metabolism and Lipid Research, Washington University School of Medicine, St Louis, MO, 63110, USA. (b) Department of Endocrinology & Nutrition, Hospital de la Santa Creu i Sant Pau, Sant Quintí, 89, 08041, Barcelona, Spain.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Elevated serum CD40 as a potential biomarker for the differential diagnosis of acute thyrotoxic myopathy.
Elevated serum CD40 as a potential biomarker for the differential diagnosis of acute thyrotoxic myopathy.
Fuente:Scientific Reports
Extracto:
The role of CD40 as an adjunct in the early
diagnosis of ATM holds clinical significance, offering new insights into the
differential diagnosis and treatment of ATM.
institución:(a) Department of Endocrinology, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China. (b) Department of Endocrinology, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Association of whole blood heavy metal concentrations with kidney function.
Association of whole blood heavy metal concentrations with kidney function.
Fuente:Scientific Reports
Extracto:
Concentrations of arsenic, lead, and mercury
correlated independently inversely with eGFR in a German cohort that largely had
a normal kidney function with no known exposure to heavy metals.
institución:(a) Department of Nephrology, Charité Universitätsmedizin Berlin, Berlin, Germany. (b) Fifth Department of Medicine (Nephrology/Endocrinology/Rheumatology, Pneumology), University Medical Center Mannheim, University of Heidelberg, Mannheim, Germany.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Association between Geriatric Nutritional Risk Index and all-cause mortality in individuals with osteoporotic fractures
Association between Geriatric Nutritional Risk Index and all-cause mortality in individuals with osteoporotic fractures
Fuente:Aging Clinical and Experimental Research
Tipo de trabajo:Estudio de cohortes
Extracto:
Reduced GNRI scores are linked to higher
mortality in inpatients with OPFs. The GNRI potentially serve as a predictor for
overall mortality risk in this population.
institución:(a) Department of Orthopedics, Affiliated Kunshan Hospital of Jiangsu University, No. 566 East of Qianjin Road, Suzhou, 215300, Jiangsu, China. (b) Department of Orthopedics, Affiliated Kunshan Hospital of Jiangsu University, No. 566 East of Qianjin Road, Suzhou, 215300, Jiangsu, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Analysis of the current status and characteristics of osteoporosis in adult hemophilia patients based on high-resolution peripheral quantitative computed tomography: a case control study.
Analysis of the current status and characteristics of osteoporosis in adult hemophilia patients based on high-resolution peripheral quantitative computed tomography: a case control study.
Fuente:Bmc Musculoskeletal Disorders
Extracto:
The bone health status of adult hemophilia patients in China is
worrying. The occurrence of OP may be accompanied by varying degrees of bone
loss, bone destruction, and structural abnormalities observed in both trabecular
and cortical bones of the upper and lower limbs. The condition of the trabecular
bones in the lower limbs is particularly severe. The correlation between BMD
measurements obtained from HR-pQCT and DXA is strong.
Claves:Adult Hemophilia Patients, Bone Mineral Density, Hemophilia, High-resolution Peripheral Quantitative Computed Tomography, Osteoporosis
Cita:BMC Musculoskelet Disord 2025 Mar 11; 26 (1) : 242.
Autor/es:Liu, Ying (a) Ge, Ying (b)
institución:(a) Department of Rehabilitation Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Science, Dongcheng District, Beijing, 100730, China. (b) Department of Rehabilitation Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Science, Dongcheng District, Beijing, 100730, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
International evidence-based recommendations for polycystic ovary syndrome in adolescents.
International evidence-based recommendations for polycystic ovary syndrome in adolescents.
Fuente:Bmc Medicine
Tipo de trabajo:Metanálisis
Extracto:
Extensive international engagement and
rigorous processes generated International Guideline diagnostic criteria for
adolescents that differ from adult criteria and clarified appropriate screening
and management strategies for PCOS during adolescence.
Autor/es:Peña, Alexia S (a) Witchel, Selma Feldman (b)
institución:(a) Discipline of Paediatrics and Endocrine Department, The University of Adelaide Robinson Research Institute and Women's and Children's Hospital, 72 King William Road, North Adelaide, SA, 5006, Australia. alexia.pena@adelaide.edu.au. (b) Division of Pediatric Endocrinology, UPMC Children's Hospital of Pittsburgh, University of Pittsburgh, 4401 Penn Avenue, Pittsburgh, PA, 15224, USA.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Gynecological issues in children and adolescents seen at rare-disease referral centers
Gynecological issues in children and adolescents seen at rare-disease referral centers
Fuente:Orphanet Journal of Rare Diseases
Tipo de trabajo:Estudio de cohortes
Extracto:
Repercussions of rare chronic diseases managed at
rare-disease referral centers were by far the leading reason for seeking
gynecological expertise in rare diseases. In this complex situation, the
underlying disease and its treatments interact with the gynecological
manifestations and their treatment, requiring close collaboration among all
specialists caring for each patient.
Claves:Cohort, French National Referral Center, Gynecology, Rare disease
institución:(a) Pediatric Endocrinology, Diabetology, Gynecology Department, Necker-Enfants Malades University Hospital, AP-HP Centre, 75015, Paris, France. iphigenie.cavadias@aphp.fr. (b) Gynecology Department, Port-Royal University Hospital, AP-HP Centre, 75014, Paris, France. iphigenie.cavadias@aphp.fr.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Clinical metabolomics in type 2 diabetes mellitus: from pathogenesis to biomarkers.
Clinical metabolomics in type 2 diabetes mellitus: from pathogenesis to biomarkers.
Fuente:Frontiers in Endocrinology
Extracto:
These results facilitate understanding the pathophysiology and mechanism
and supports research in accurate diagnosis, risk prediction, curative effect,
distinct stages, and prognosis judgment of T2DM.
Claves:biomarkers, clinical metabolomics, complications, stratification, type 2 diabetes mellitus (T2DM)
institución:(a) Luoyang Key Laboratory of Clinical Multiomics and Translational Medicine, Henan Key Laboratory of Rare Diseases, Endocrinology and Metabolism Center, The First Affiliated Hospital, and College of Clinical Medicine of Henan University of Science and Technology, Luoyang, China. (b) Luoyang Key Laboratory of Clinical Multiomics and Translational Medicine, Henan Key Laboratory of Rare Diseases, Endocrinology and Metabolism Center, The First Affiliated Hospital, and College of Clinical Medicine of Henan University of Science and Technology, Luoyang, China.
Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
