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La creciente cantidad de artículos con Acceso Abierto (Open
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estructura de un estudio: especialidad, modalidad del estudio,
fuente, fechas de publicación y selección, definición de la fuente,
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Sociedad Iberoamericana de Información Científica (SIIC) selects
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Bases.
The increasing number of Open Access articles widens the reading offer
but, also, such myriad complicates the readers search of fundamental
articles. To facilitate this, SIIC biomedical professionals daily
consult a profuse amount of documents that will feed
Authorized Full Texts (TCA, Spanish acronym).
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their corresponding sources.
SIIC created, produced and handles the AFT software that deciphers
the various documentary fields that form part of the structure of a
study: specialty, study style, source, publication and selection
dates, source definition, query limitations, summary in Spanish,
etc.
While most of the selected texts belong to original articles,
reviews, and guidelines, readers will also find commentaries,
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that may lead to discussions or clarifications.
Socioeconomic and demographic disparities in the impact of digestive diseases in the middle East and North Africa (MENA) region.
Socioeconomic and demographic disparities in the impact of digestive diseases in the middle East and North Africa (MENA) region.
Fuente:International Journal For Equity in Health
Extracto:
Despite a reduction in mortality and DALY
rates, the persistently high incidence rates of DD in the MENA region underscores
ongoing public health challenges. Socioeconomic factors strongly influence
disease burden, highlighting the need for targeted interventions to address
disparities and improve digestive disease outcomes across the region.
Claves:Digestive diseases, Incidence trends, MENA region, Public health, Socioeconomic disparities
Cita:Int J Equity Health 2025 Mar 27; 24 (1) : 85.
institución:(a) Department of Medicine, Allegheny Health Network, 320 E N Ave, 15212, Pittsburgh, PA, USA. Otaani19@gmail.com. (b) Department of Medicine, Staten Island University Hospital, Northwell Health, Staten Island, NY, USA.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Glucocorticoids can reduce mortality in patients with severe community-acquired pneumonia
Glucocorticoids can reduce mortality in patients with severe community-acquired pneumonia
Fuente:European Journal of Medical Research
Tipo de trabajo:Revisión sistemática
Extracto:
Glucocorticoids can reduce mortality in patients
with sCAP, and the effect may vary depending on the type and the dose of
glucocorticoids used. Additionally, glucocorticoid treatment can lead to a
shorter duration of mechanical ventilation, as well as the length of ICU stay,
without increasing the risk of gastrointestinal bleeding or secondary infection
in patients with sCAP. PROSPERO registration: CRD42023416525.
Claves:Corticosteroids, Meta-analysis, Pneumonia, Severe community-acquired pneumonia
Cita:Eur J Med Res 2025 Mar 28; 30 (1) : 215.
Autor/es:Gu, Xue (a) Yang, Penglei (b)
institución:(a) Department of Critical Care Medicine, Jiangdu People'S Hospital Affiliated to Yangzhou University, Yangzhou, 225200, Jiangsu, China. (b) Department of Critical Care Medicine, Jiangdu People'S Hospital Affiliated to Yangzhou University, Yangzhou, 225200, Jiangsu, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Integrative analysis of bulk and single-cell sequencing reveals TNFSF9 as a potential regulator in microsatellite instability stomach adenocarcinoma.
Integrative analysis of bulk and single-cell sequencing reveals TNFSF9 as a potential regulator in microsatellite instability stomach adenocarcinoma.
Fuente:European Journal of Medical Research
Extracto:
These findings
provide new insights into the TME of MSI in STAD, emphasizing the significant
role of TNFSF9 in shaping MSI-specific TME, enhancing immunotherapy efficacy, and
improving patient survival.
institución:(a) Department of Gastrointestinal Surgery, Department of General Surgery, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, 510080, Guangdong, China. (b) Department of Gastrointestinal Surgery, Department of General Surgery, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, 510080, Guangdong, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Level of intestinal permeability markers and selected aspects of diet and BMI of Polish e-sports players.
Level of intestinal permeability markers and selected aspects of diet and BMI of Polish e-sports players.
Fuente:Journal of Health, Population, and Nutrition
Extracto:
Excessive body
weight and a poor health diet were shown to have a negative effect on increasing
intestinal permeability, suggesting the rationale for monitoring and
rationalizing diet and nutritional status to optimize the intestinal microbiota
of e-sportsmen.
institución:(a) Department of Sports Medicine and Human Nutrition, Institute of Biomedical Sciences, University of Physical Culture, Jana Pawła II 78, 31-571, Kraków, Poland. paulina.mazur@awf.krakow.pl. (b) Department of Sports Dietetics, Gdansk University of Physical Education and Sport, Kazimierza Górskiego 1, Gdansk, 80-336, Poland.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Acute total intestinal volvulus caused by sclerosing mesenteritis
Acute total intestinal volvulus caused by sclerosing mesenteritis
Fuente:Journal of Medical Case Reports
Tipo de trabajo:Revisión
Extracto:
Intestinal volvulus due to sclerosing mesenteric inflammation is an exceedingly
rare occurrence. Clinicians should maintain a high index of suspicion for this
condition when encountering cases of intestinal volvulus attributed to mesenteric
tumors. Prompt and decisive surgical intervention is crucial for saving lives and
for preserving as much of the intestinal tract as possible.
institución:(a) Department of Gastrointestinal Surgery, The First Hospital of Hebei Medical University, No.89 Donggang Road, Shijiazhuang, 050030, People's Republic of China. (b) Department of Gastrointestinal Surgery, The First Hospital of Hebei Medical University, No.89 Donggang Road, Shijiazhuang, 050030, People's Republic of China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Autor/es:Pęczuła, Agnieszka (a) Czaplicki, Adam (b)
institución:(a) Department of Gastroenterology and Internal Medicine, Medical University of Warsaw, ul. Banacha 1a, 02-097 Warsaw, Poland. (b) Department of Gastroenterology and Internal Medicine, Medical University of Warsaw, ul. Banacha 1a, 02-097 Warsaw, Poland.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Molecular Abnormalities and Carcinogenesis in Barrett's Esophagus: Implications for Cancer Treatment and Prevention.
Molecular Abnormalities and Carcinogenesis in Barrett's Esophagus: Implications for Cancer Treatment and Prevention.
Fuente:Genes
Tipo de trabajo:Revisión
Extracto:
BE is the primary preneoplastic condition for EAC. A
deeper understanding of its molecular transformation can enhance surveillance
protocols, optimize the management of gastroesophageal reflux inflammation, and
refine prevention and therapeutic strategies, ultimately contributing to a
reduction in the global burden of EAC.
Autor/es:de Melo Viana, Thaís Cabral (a) Nakamura, Eric Toshiyuki (b)
institución:(a) Department of Gastroenterology, Universidade de Sao Paulo, Sao Paulo 05508-220, Brazil. (b) Department of Gastroenterology, Universidade de Sao Paulo, Sao Paulo 05508-220, Brazil.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Clinical Implications of Cell-Free DNA in Managing BRAF V600E Mutation-Positive Colorectal Cancer.
Clinical Implications of Cell-Free DNA in Managing BRAF V600E Mutation-Positive Colorectal Cancer.
Fuente:Genes
Extracto:
Conclusions: These findings support cfDNA BRAF(V600E) as a promising biomarker
for monitoring treatment response and MRD detection in BRAF(V600E)-mutant CRC,
reinforcing its role in guiding personalized treatment strategies and
postoperative surveillance.
institución:(a) Department of Gastroenterological Surgery, Nippon Medical School, 1-1-5 Sendagi, Bunkyo-ku, Tokyo 113-8602, Japan. (b) Department of Gastroenterological Surgery, Nippon Medical School, 1-1-5 Sendagi, Bunkyo-ku, Tokyo 113-8602, Japan.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
institución:(a) Unit of Medical Genetics, Department of Molecular Medicine, University of Pavia, 27100 Pavia, Italy. (b) Unit of Medical Genetics, Department of Molecular Medicine, University of Pavia, 27100 Pavia, Italy.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Phenotypical Characterization of C9ALS Patients from the Emilia Romagna Registry of ALS: A Retrospective Case-Control Study.
Phenotypical Characterization of C9ALS Patients from the Emilia Romagna Registry of ALS: A Retrospective Case-Control Study.
Fuente:Genes
Extracto:
In our dataset, we show
an overall increased disease progression rate in C9ALS patients and hint at
sex-specific discrepancies in some phenotypical characteristics. We also suggest
a possible clinically relevant involvement of C9ORF72 expansion in metabolism and
autoimmunity.
Claves:C9ORF72, amyotrophic lateral sclerosis, clinical features, phenotype, population-based study
Cita:Genes (Basel) 2025 Mar 4; 16 (3)
Autor/es:Ghezzi, Andrea (a) Gianferrari, Giulia (b)
institución:(a) Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, 41125 Modena, Italy. (b) Neurology Unit, Azienda Ospedaliero Universitaria di Modena, 41126 Modena, Italy.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Unraveling the Extra Virgin Olive Oil Effect on Inflammation and on Gut and Saliva Microbiota.
Unraveling the Extra Virgin Olive Oil Effect on Inflammation and on Gut and Saliva Microbiota.
Fuente:Biomolecules
Extracto:
Moreover, EVOO intake modulated gut and oral microbiota, increasing Bacteroidota
in both ecological niches and Bacillota in the oral microbiota, both phyla being
associated with health, demonstrating a prebiotic effect.
institución:(a) CBQF-Centro de Biotecnologia e Química Fina-Laboratório Associado, Escola Superior de Biotecnologia, Universidade Católica Portuguesa, Rua Diogo Botelho 1327, 4169-005 Porto, Portugal. (b) Centro de Investigação Interdisciplinar em Saúde (CIIS), Faculdade de Medicina Dentária, Universidade Católica Portuguesa, Estrada da Circunvalação, 3504-505 Viseu, Portugal.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Indoleacetylglutamine Pathway Is a Potential Biomarker for Cardiovascular Diseases.
Indoleacetylglutamine Pathway Is a Potential Biomarker for Cardiovascular Diseases.
Fuente:Biomolecules
Extracto:
Our findings may pave the way for novel approaches in CVD risk
assessment and potential therapeutic interventions targeting the gut-heart axis.
Claves:cardiovascular diseases, gut microbiota, indoleacetylglutamine, metabolomics
Cita:Biomolecules 2025 Mar 5; 15 (3)
Autor/es:Naja, Khaled (a) Anwardeen, Najeha (b)
institución:(a) Biomedical Research Center, QU Health, Qatar University, Doha P.O. Box 2713, Qatar. (b) Biomedical Research Center, QU Health, Qatar University, Doha P.O. Box 2713, Qatar.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Genetic Analysis and Predictive Modeling of COVID-19 Severity in a Hospital-Based Patient Cohort.
Genetic Analysis and Predictive Modeling of COVID-19 Severity in a Hospital-Based Patient Cohort.
Fuente:Biomolecules
Extracto:
Our results combining human genetic information with clinical data may help
to improve risk assessment for the development of a severe outcome of COVID-19.
institución:(a) Inflammation & Biomarkers Group, Biobizkaia Health Research Institute, 48903 Barakaldo, Spain. (b) Physiology Department, Faculty of Medicine and Nursery, Basque Country University (UPV/EHU), 48940 Leioa, Spain.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Probiotics and Diet in Rosacea: Current Evidence and Future Perspectives.
Probiotics and Diet in Rosacea: Current Evidence and Future Perspectives.
Fuente:Biomolecules
Extracto:
Ultimately, this article improves our understanding of the gut-skin
axis in rosacea, focusing on how probiotic supplementation and diet could improve
the clinical management of patients affected by this common and debilitating
disease.
Autor/es:Manfredini, Marco (a) Barbieri, Michele (b)
institución:(a) Department of Dermatology, University of Modena and Reggio Emilia, 41124 Modena, Italy. (b) Department of Dermatology, University of Modena and Reggio Emilia, 41124 Modena, Italy.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Reliability of Composite Autonomic Symptom Score (COMPASS)-31 in Congenital Central Hypoventilation Syndrome.
Reliability of Composite Autonomic Symptom Score (COMPASS)-31 in Congenital Central Hypoventilation Syndrome.
Fuente:Pediatric Pulmonology
Extracto:
COMPASS-31 identified some aspects of
CCHS-related ANSD, and scores correlate with objective ANS function measures,
supporting the potential utility of COMPASS-31 in CCHS.
Claves:CO2 chemosensitivity, Holter electrocardiogram, autonomic nervous system dysfunction
Cita:Pediatr Pulmonol 2025 Apr; 60 (4) : e71072.
Autor/es:Dudoignon, Benjamin (a) Bokov, Plamen (b)
institución:(a) Service de Physiologie Pédiatrique -Centre du Sommeil - CRMR Hypoventilations alvéolaires rares, AP-HP, Hôpital Robert Debré, INSERM NeuroDiderot, Université de Paris Cité, Paris, France. (b) Service de Physiologie Pédiatrique -Centre du Sommeil - CRMR Hypoventilations alvéolaires rares, AP-HP, Hôpital Robert Debré, INSERM NeuroDiderot, Université de Paris Cité, Paris, France.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Characterization of T-Cell Receptor Profiles Predicts Survival Situation in Patients with Hepatocellular Carcinoma.
Characterization of T-Cell Receptor Profiles Predicts Survival Situation in Patients with Hepatocellular Carcinoma.
Fuente:Technology in Cancer Research & Treatment
Extracto:
Also, our analysis identified a number of TCR genes that
are significantly associated with survival, and these may not only serve as
prognostic biomarkers but may also play an important role in antigen-specific
immunotherapy.
Cita:Technol Cancer Res Treat 2025 Jan-Dec; 24 : 15330338251329699.
Autor/es:Wang, Fengyan (a) Deng, Li (b)
institución:(a) Department of Gastroenterology, The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, Jinan, China. (b) Shandong Provincial Key Laboratory of Neuroprotective Drugs, Zibo, China.
Conflicto:Conflicting InterestsThe authors declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
The Role and Mechanisms of Probiotic Supplementation on Depressive Symptoms
The Role and Mechanisms of Probiotic Supplementation on Depressive Symptoms
Fuente:Current Nutrition Reports
Tipo de trabajo:Revisión
Extracto:
However, the mechanistic pathways of the
MGBA require further investigation and additional human clinical trials are
necessary to evaluate the role of probiotics on depression.
Claves:Anxiety, Depression, Gut microbiota, Microbiota-gut-brain axis, Probiotics
institución:(a) Discipline of Food, Nutrition and Dietetics, Department of Sport, Exercise and Nutrition Sciences, School of Allied Health, Human Services and Sport, La Trobe University, Melbourne, VIC, 3086, Australia. (b) Discipline of Food, Nutrition and Dietetics, Department of Sport, Exercise and Nutrition Sciences, School of Allied Health, Human Services and Sport, La Trobe University, Melbourne, VIC, 3086, Australia.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Influence of menstrual cycle and oral contraception on taxonomic composition and gas production in the gut microbiome.
Influence of menstrual cycle and oral contraception on taxonomic composition and gas production in the gut microbiome.
Fuente:Journal of Medical Microbiology
Extracto:
Our findings offer new
perspectives on the microbiome-hormone-gas production nexus, potentially
broadening our understanding of the systemic implications of OCs.
Claves:human gut microbiome, breath hydrogen, breath methane, oral contraceptives, sex hormones
Cita:J Med Microbiol 2025 Mar; 74 (3)
Autor/es:Terrazas, Fernanda (a) Kelley, Scott T (b)
institución:(a) Department of Biology, San Diego State University, San Diego, USA. (b) Department of Biology, San Diego State University, San Diego, USA.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Role of aspirin on colorectal cancer risk and bacterial translocation to bloodstream.
Role of aspirin on colorectal cancer risk and bacterial translocation to bloodstream.
Fuente:Plos One
Extracto:
This study provides additional data on the favorable
role of aspirin on IA and CRC risks and supports the hypothesis of an involvement
of intestinal bacterial translocation to the bloodstream.
Cita:PLoS One 2025; 20 (3) : e0319750.
Autor/es:Mignozzi, Silvia (a) De Pinto, Giuseppe (b)
institución:(a) Department of Clinical Science and Community Health, Dipartimento di Eccellenza 2023-2027, University of Milan, Milan, Italy. (b) Department of Clinical Science and Community Health, Dipartimento di Eccellenza 2023-2027, University of Milan, Milan, Italy.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
