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Non-invasive biomarkers for detecting progression toward hypovolemic cardiovascular instability in a lower body negative pressure model.
Non-invasive biomarkers for detecting progression toward hypovolemic cardiovascular instability in a lower body negative pressure model.
Fuente:Scientific Reports
Extracto:
EIT, alone or in machine learning-based combination, appears
promising as a technology for early detection of progression toward hemodynamic
instability.
Cita:Sci Rep 2024 Apr 15; 14 (1) : 8719.
Autor/es:Murphy, Ethan K (a) Bertsch, Spencer R (b)
institución:(a) Thayer School of Engineering, Dartmouth College, Hanover, NH, 03755, USA. ethan.k.murphy@dartmouth.edu. (b) Thayer School of Engineering, Dartmouth College, Hanover, NH, 03755, USA.
Conflicto:NP has issued patents in this subject, NP/RH/JE/VV/EM have a patent pending in related technology, NP/VV/RH/JE are founders of a company developing technologies for diagnosis of acute system disease. All other authors declare that they do not have any competing interests.
The global patent landscape of emerging infectious disease monkeypox.
The global patent landscape of emerging infectious disease monkeypox.
Fuente:Bmc Infectious Diseases
Extracto:
Monkeypox-related therapeutic
innovation is geographically limited with strong international intellectual
property right barriers though it has increased rapidly in recent years. The
transparent licensing of patent knowledge is driven by the merger and acquisition
model, and the venture capital, intellectual property and contract research
organization model. Currently, the patent thicket phenomenon in the monkeypox
field may slow the progress of efforts to combat monkeypox. Enterprises should
pay more attention to the sharing of technical knowledge, make full use of drug
repurposing strategies, and promote innovation of monkeypox-related technology in
hotspots of antivirals (such as tecovirimat, cidofovir, brincidofovir), vaccines
(JYNNEOS, ACAM2000), herbal medicine and gene therapy.
institución:(a) Center for Medical Artificial Intelligence, Qingdao Academy of Chinese Medical Sciences, Shandong University of Traditional Chinese Medicine, 266112, Qingdao, China. (b) Department of Cardiovascular Surgery, The Affiliated Hospital of Qingdao University, 266000, Qingdao, China.
Risk factors of different mortality periods in older patients with end-stage renal disease undergoing urgent-start peritoneal dialysis: a retrospective observational study.
Risk factors of different mortality periods in older patients with end-stage renal disease undergoing urgent-start peritoneal dialysis: a retrospective observational study.
Fuente:Bmc Geriatrics
Extracto:
Different risk factors correlated with mortality in older adults with
ESRD within and after six months of undergoing USPD, including baseline NYHA
class III-IV cardiac function, WBC count, potassium, and calcium levels.
Claves:Analysis of death, Elderly, Six months, Urgent-start dialysis
Cita:BMC Geriatr 2024 Apr 15; 24 (1) : 343.
Autor/es:Guo, Shizheng (a) Yang, Liming (b)
institución:(a) Department of Nephrology, the Second Bethune Hospital of Jilin University, 130022, Changchun, Jilin Province, China. (b) Department of Nephrology, the First Bethune Hospital of Jilin University-the Eastern Division, 130021, Changchun, Jilin Province, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Associations between cardiovascular diseases and cancer mortality: insights from a retrospective cohort analysis of NHANES data.
Associations between cardiovascular diseases and cancer mortality: insights from a retrospective cohort analysis of NHANES data.
Fuente:Bmc Public Health
Extracto:
HF was associated with an
increased risk of mortality from cancer, regardless of cancer history, while HBP,
CHD and DM showed no significant association. These findings underscore the
importance of understanding the mechanisms behind the increased risk of cancer
mortality following HF.
Claves:Cancer mortality, Cardiovascular disease, Heart failure, National health and nutrition examination survey
Cita:BMC Public Health 2024 Apr 15; 24 (1) : 1049.
Autor/es:Ge, Chenliang (a) Jiang, Zhiyuan (b)
institución:(a) Department of Cardiology, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi Zhuang Autonomous Region, China. (b) Department of Cardiology, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi Zhuang Autonomous Region, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Risk factors for and risk of all-cause and atherosclerotic cardiovascular disease mortality in people with type 2 diabetes and peripheral artery disease
Risk factors for and risk of all-cause and atherosclerotic cardiovascular disease mortality in people with type 2 diabetes and peripheral artery disease
Fuente:Cardiovascular Diabetology
Tipo de trabajo:Estudio de cohortes
Extracto:
The presence of T2D with
concomitant PAD is related to an increased risk of both all-cause and
cardiovascular mortality compared with individuals with only PAD. This argues for
implementing optimized and intensive treatment strategies for individuals with
both conditions.
institución:(a) Department of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Medicinaregatan 18G, Gothenburg, 413 45, Sweden. tarik.avdic@gu.se. (b) Department of Internal Medicine, Sahlgrenska University Hospital/Östra, Gothenburg, Sweden. tarik.avdic@gu.se.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Correlation of pre-existing comorbidities with disease severity in individuals infected with SARS-COV-2 virus.
Correlation of pre-existing comorbidities with disease severity in individuals infected with SARS-COV-2 virus.
Fuente:Bmc Public Health
Extracto:
Our
study has shown that comorbidities such as urinary system diseases and
cardiovascular diseases tend to have a negative impact on Covid-19, leading to a
poor outcome resulting in death, while diabetes mellitus and hypertension have an
impact but without statistical significance.
Claves:Cardiovascular diseases, Comorbidities, Diabetes mellitus, Hypertension, Urinary system diseases
Cita:BMC Public Health 2024 Apr 15; 24 (1) : 1053.
Autor/es:Marušić, Jasmina (a) Hasković, Edhem (b)
institución:(a) Department of Health Care, Faculty of Medicine, University of Zenica, Zenica, Bosnia and Herzegovina. jasminavele@gmail.com. (b) Marjanovića put 39, 72000, Zenica, Bosnia and Herzegovina. jasminavele@gmail.com.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Longitudinal association of grip strength with cardiovascular and all-cause mortality in older urban Lithuanian population.
Longitudinal association of grip strength with cardiovascular and all-cause mortality in older urban Lithuanian population.
Fuente:Bmc Public Health
Extracto:
The mean GS was significantly higher among survivors' men and women
as compared to deceased from CVD and other causes of death. Risk of all-cause
mortality significantly increased with decreasing of GS.
Claves:All-cause mortality, CVD mortality risk, Grip strength, Longitudinal study
Cita:BMC Public Health 2024 Apr 15; 24 (1) : 1040.
institución:(a) Institute of Cardiology, Medical Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania. lolita.sileikiene@lsmu.lt. (b) Institute of Cardiology, Medical Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Dyslipidemia and associated factors among adult cardiac patients: a hospital-based comparative cross-sectional study.
Dyslipidemia and associated factors among adult cardiac patients: a hospital-based comparative cross-sectional study.
Fuente:European Journal of Medical Research
Extracto:
Dyslipidemia was high among the
study participants. Overweight, obesity, central adiposity, and high blood
pressure were significantly associated with dyslipidemia in cardiac patients.
This alarms the need for lipid profile assessment for patients periodically, with
treatment follow-up to monitor any rising patterns and cardiovascular-related
risks.
institución:(a) Hawassa University Comprehensive Specialized Hospital, Hawassa, Ethiopia. (b) Department of Clinical Chemistry, School of Biomedical and Laboratory Sciences, College of Medicine and Health Sciences, University of Gondar, 196, Gondar, Ethiopia.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Extensive surgical resections for rare pleural neoplasms: a single-center experience with a yolk sac tumor and synovial sarcoma.
Extensive surgical resections for rare pleural neoplasms: a single-center experience with a yolk sac tumor and synovial sarcoma.
Fuente:World Journal of Surgical Oncology
Extracto:
Neo-adjuvant
chemotherapy followed by extensive thoracic surgery, including hyperthermic
intrathoracic chemotherapy, is a feasible treatment strategy for non-mesothelioma
primary pleural neoplasms, but careful follow-up is required.
Autor/es:Vandaele, Tom (a) Van Slambrouck, Jan (b)
institución:(a) Department of Thoracic Surgery, University Hospitals Leuven, Leuven, Belgium. vandaeletom@live.be. (b) Department of Chronic Diseases and Metabolism, Laboratory of Respiratory Diseases and Thoracic Surgery (BREATHE), KU Leuven, Leuven, Belgium. vandaeletom@live.be.
Disordered GPR43/NLRP3 expression in peripheral leukocytes of patients with atrial fibrillation is associated with intestinal short chain fatty acids levels.
Disordered GPR43/NLRP3 expression in peripheral leukocytes of patients with atrial fibrillation is associated with intestinal short chain fatty acids levels.
Fuente:European Journal of Medical Research
Extracto:
Disrupted interactions between GPR43 and NLRP3 expression in peripheral blood
leukocytes, associated with reduced intestinal GM-derived SCFAs, especially
acetic acid, may be involved in AF development and left atrial enlargement by
enhancing circulating inflammation.
institución:(a) Department of Cardiology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing University, No. 321 Zhongshan Road, Nanjing, 210008, China. (b) Beijing Key Laboratory of Hypertension, Beijing Chaoyang Hospital, Heart Center, Capital Medical University, 8th Gongtinanlu Rd, Chaoyang District, Beijing, 100020, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Polymorphic ventricular tachycardia and cardiac arrest from abiraterone-induced hypokalemia
Polymorphic ventricular tachycardia and cardiac arrest from abiraterone-induced hypokalemia
Fuente:Journal of Medical Case Reports
Tipo de trabajo:Caso clínico
Extracto:
A broad differential diagnosis for polymorphic ventricular tachycardia is
essential in identifying and treating patients presenting in this rhythm. Here we
present a case of iatrogenic polymorphic ventricular tachycardia secondary to
oncologic treatment.
Claves:Arrhythmia, Critical care, Electrolyte derangement, Medication side effect
institución:(a) Department of Cardiology, Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA. (b) Department of Pharmacy, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Diabetes mellitus does not alter mortality or hospitalisation risk in patients with newly diagnosed heart failure with preserved ejection fraction: Time to rethink pathophysiological models of disease progression.
Diabetes mellitus does not alter mortality or hospitalisation risk in patients with newly diagnosed heart failure with preserved ejection fraction: Time to rethink pathophysiological models of disease progression.
Fuente:Diabetes & Vascular Disease Research
Tipo de trabajo:Estudio de cohortes
Extracto:
In unselected patients with newly diagnosed HF, diabetes is not an
adverse prognostic marker in patients with HFpEF, but is in HFrEF.
Cita:Diab Vasc Dis Res 2024 Mar-Apr; 21 (2) : 14791641231224241.
Autor/es:Gierula, John (a) Straw, Sam (b)
institución:(a) Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, UK. RINGGOLD: 573267 (b) Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, UK. RINGGOLD: 573267
Conflicto:Declaration of conflicting interestsThe author(s) declared the following potential conflicts of interest with respect to the research, authorship, and/or publication of this article: John Gierula has received speaker fees from Abbott and Medtronic and consultancy fees from Microport. Klaus Witte has received speaker fees from Medtronic, Microport, Abbott, Cardiac Dimensions, Pfizer, Bayer, and Bristol-Myers Squibb. Peter Grant has received speaker...
fees from AstraZenica. Sam Straw has received nonfinancial support from AstraZeneca. Stephen Wheatcroft has received speaker fees from AstraZeneca, Bayer, Boehringer Ingelheim, Lilly and NovNordisk. Mark Kearney has received speaker fees from Merck and Novo Nordisk and unrestricted research awards from Medtronic.
Hypertension, Cardiovascular Risk Factors, and Uterine Fibroid Diagnosis in Midlife.
Hypertension, Cardiovascular Risk Factors, and Uterine Fibroid Diagnosis in Midlife.
Fuente:Jama Network Open
Tipo de trabajo:Estudio de cohortes
Extracto:
AND
RELEVANCE: Participants with untreated and new-onset hypertension had increased
risk of newly diagnosed fibroids, whereas those taking antihypertensive treatment
had lower risk, suggesting that blood pressure control may provide new strategies
for fibroid prevention.
Cita:JAMA Netw Open 2024 Apr 1; 7 (4) : e246832.
Autor/es:Mitro, Susanna D (a) Wise, Lauren A (b)
institución:(a) Division of Research, Kaiser Permanente Northern California, Oakland. (b) Department of Epidemiology, Boston University School of Public Health, Boston, Massachusetts.
Conflicto:Conflict of Interest Disclosures: Dr Wise reported receiving grants from the National Institutes of Health (NIH), personal fees from The Gates Foundation and Abbvie, Inc, and in-kind donations for primary data collection in a study outside the submitted work from Swiss Precision Diagnostics (home pregnancy tests) and Kindara.com (fertility applications). Dr Waetjen reported receiving grants from Accessa Health Inc outside...
the submitted work. Dr Solomon reported receiving grants from CorEvitas, Janssen, and Novartis outside the submitted work. Dr Thurston reported receiving personal fees from Astellas Pharma, Bayer, Hello Therapeutics, Happify Health, and Vira Health outside the submitted work. Dr Santoro reported receiving grants from Menogenix, Inc, and personal fees from Astellas Pharma, Ansh Labs, Amazon, and FertilityIQ outside the submitted work. No other disclosures were reported.
PD-L1 inhibitors combined with whole brain radiotherapy in patients with small cell lung cancer brain metastases: Real-world evidence.
PD-L1 inhibitors combined with whole brain radiotherapy in patients with small cell lung cancer brain metastases: Real-world evidence.
Fuente:Cancer Medicine
Extracto:
Our results indicated that WBRT combined with immunotherapy improved survival in
SCLC-BMs patients compared to WBRT monotherapy. Administering WBRT prior to ICI
treatment is associated with improved survival outcomes compared to WBRT
following ICI treatment, for patients with SCLC-BMs. These findings highlight the
significance of conducting further prospective researches on combination
strategies of intracranial radiotherapy and ICI in SCLC-BMs patients.
Claves:extensive small cell lung cancer, immunotherapy, intracranial metastasis, radiotherapy
Cita:Cancer Med 2024 Apr; 13 (7) : e7125.
Autor/es:Huang, Litang (a) Chen, Shen (b)
institución:(a) Department of Radiation Oncology, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai, China. (b) Department of Oncology, Shanghai Pulmonary Hospital, Tongji University, School of Medicine, Shanghai, China.
Conflicto:The authors have no relevant financial or non‐financial interests to disclose.
Using Focus Groups to Explore Older Black Men's Perception of Dietary Interventions.
Using Focus Groups to Explore Older Black Men's Perception of Dietary Interventions.
Fuente:American Journal of Men's Health
Extracto:
Findings from this study should inform
the design of future dietary interventions for AD prevention to enhance
participation among older Black men.
Claves:Alzheimer’s disease, diet, men of color, mixed methods, older adults
Cita:Am J Mens Health 2024 Mar-Apr; 18 (2) : 15579883241241973.
Autor/es:Shaw, Ashley R (a) Vidoni, Eric D (b)
institución:(a) Department of Neurology, University of Kansas Medical Center, Kansas City, KS, USA. (b) Department of Neurology, University of Kansas Medical Center, Kansas City, KS, USA.
Conflicto:Declaration of Conflicting InterestsThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
[Optimizing the management of heart failure: structuring the care pathway].
[Optimizing the management of heart failure: structuring the care pathway].
Fuente:Soins; la Revue de Reference Infirmiere
Extracto:
Around the main heart failure,
assistance and transplantation unit at Toulouse University Hospital, several
structures have been put in place to better manage heart failure patients and
improve their care pathway.
institución:(a) Unité Icat, service de cardiologie, institut Cardiomet, CHU de Toulouse, hôpital Rangueil, 1 avenue du Pr Jean-Poulhès, TSA 50032, 31059 Toulouse cedex 9, France. (b) Unité Icat, service de cardiologie, institut Cardiomet, CHU de Toulouse, hôpital Rangueil, 1 avenue du Pr Jean-Poulhès, TSA 50032, 31059 Toulouse cedex 9, France.
Cooking with liquefied petroleum gas or biomass and fetal growth outcomes
Cooking with liquefied petroleum gas or biomass and fetal growth outcomes
Fuente:The Lancet. Global Health
Tipo de trabajo:Estudio aleatorizado y controlado
Extracto:
TRANSLATIONS: For the Kinyarwanda, Spanish and Tamil translations of the abstract
see Supplementary Materials section.
Cita:Lancet Glob Health 2024 May; 12 (5) : e815-e825.
Autor/es:Checkley, William (a) Thompson, Lisa M (b)
institución:(a) Division of Pulmonary and Critical Care, School of Medicine, Johns Hopkins University, Baltimore, MD, USA; Center for Global Non-Communicable Disease Research and Training, School of Medicine, Johns Hopkins University, Baltimore, MD, USA. Electronic address: wcheckl1@jhmi.edu. (b) Nell Hodgson Woodruff School of Nursing, Emory University, Atlanta, GA, USA.
Conflicto:Declaration of interests LW reports a grant from the US National Institute of Environmental Health Sciences. All other authors declare no competing interests.
Extracto:
Here, we discuss current management strategies for obesity, including
dietary intervention, pharmacological therapies and optimisation, and bariatric
surgery.
institución:(a) St George's University Hospitals NHS Foundation Trust, London, UK. Electronic address: sheena.gupta1@nhs.net. (b) St George's University Hospitals NHS Foundation Trust, London, UK.
The weight of obesity in hypertrophic cardiomyopathy.
The weight of obesity in hypertrophic cardiomyopathy.
Fuente:Clinical Medicine (london, England)
Extracto:
In this review, we aim
to summarise the effects of obesity in the cardiac phenotype, the symptoms and
management in patients with hypertrophic cardiomyopathy.
institución:(a) Barts Health NHS Trust, London, UK. Electronic address: marina.zaromytidou@nhs.net. (b) Barts Health NHS Trust, London, UK; William Harvey Research Institute, Queen Mary University London, UK; Institute for Cardiovascular Science, University College London, London, UK.