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fuente, fechas de publicación y selección, definición de la fuente,
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Sociedad Iberoamericana de Información Científica (SIIC) selects
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Bases.
The increasing number of Open Access articles widens the reading offer
but, also, such myriad complicates the readers search of fundamental
articles. To facilitate this, SIIC biomedical professionals daily
consult a profuse amount of documents that will feed
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SIIC created, produced and handles the AFT software that deciphers
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While most of the selected texts belong to original articles,
reviews, and guidelines, readers will also find commentaries,
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that may lead to discussions or clarifications.
Developing and Testing the Usability of a Novel Child Abuse Clinical Decision Support System: Mixed Methods Study.
Developing and Testing the Usability of a Novel Child Abuse Clinical Decision Support System: Mixed Methods Study.
Fuente:Journal of Medical Internet Research
Extracto:
With its user-centered design and
evidence-based content, the CA-CDS can aid providers in the real-time recognition
and evaluation of infant physical abuse and has the potential to reduce the
number of missed cases.
Claves:CDS, child, child abuse, children, clinical decision support, clinical decision support system, natural language processing, pediatrics, physical abuse, usability
Cita:J Med Internet Res 2024 Mar 29; 26 : e51058.
Autor/es:Thomas, Amy (a) Asnes, Andrea (b)
institución:(a) Department of Pediatrics, Yale University School of Medicine, New Haven, CT, United States. (b) Department of Pediatrics, Yale University School of Medicine, New Haven, CT, United States.
Proceedings of the 6th Asia Dengue Summit, June 2023.
Proceedings of the 6th Asia Dengue Summit, June 2023.
Fuente:Plos Neglected Tropical Diseases
Extracto:
With
more than 51 speakers and 451 delegates from over 24 countries, 10 symposiums,
and 2 full days, the 6th ADS highlighted the growing threat of dengue and its
antigenic evolution, flagged the urgent need to overcome vaccine hesitancy and
misinformation crisis, and focused on dengue control policies, newer diagnostics,
therapeutics and vaccines, travel-associated dengue, and strategies to improve
community involvement.
institución:(a) Tropical Medicine Cluster, Center of Excellence in Critical Care Nephrology, Faculty of Medicine, Chulalongkorn University, Excellence Center for Critical Care Nephrology, King Chulalongkorn Memorial Hospital, Thailand. (b) Program in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Comparison of raw accelerometry data from ActiGraph, Apple Watch, Garmin, and Fitbit using a mechanical shaker table.
Comparison of raw accelerometry data from ActiGraph, Apple Watch, Garmin, and Fitbit using a mechanical shaker table.
Fuente:Plos One
Extracto:
Future studies could explore device-agnostic and harmonization methods
for estimating physical activity using the raw accelerometry signals from the
consumer wearables studied herein.
Cita:PLoS One 2024; 19 (3) : e0286898.
Autor/es:White, James W 3rd (a) Finnegan, Olivia L (b)
institución:(a) Department of Exercise Science, University of South Carolina, Columbia, SC, United States of America. (b) Department of Exercise Science, University of South Carolina, Columbia, SC, United States of America.
Conflicto:I have read the journal’s policy and the authors of this manuscript have the following competing interests: Unrelated to this work Dr. Weaver and Dr. Armstrong report board membership and ownership shares in Trackster LLC. Unrelated to this work Dr. de Zambotti reports grants from Noctrix Health and Verily Life Science LLC (Alphabet Inc.), and is a co-founder and Chief...
ef Scientific Officer at Lisa Health Inc. and has ownership of shares in Lisa Health.
Secondary bone marrow graft loss after third-party virus-specific T cell infusion
Secondary bone marrow graft loss after third-party virus-specific T cell infusion
Fuente:Nature Communications
Tipo de trabajo:Caso clínico
Extracto:
This case thus demonstrates a rare but serious side effect of VST
therapy.
Cita:Nat Commun 2024 Mar 29; 15 (1) : 2749.
Autor/es:Keller, Michael D (a) Schattgen, Stefan A (b)
institución:(a) Center for Cancer and Immunology Research, Children's National Hospital, Washington, DC, USA. (b) Division of Allergy and Immunology, Children's National Hospital, Washington, DC, USA.
Conflicto:CMB is on the scientific advisory boards for Catamaran Bio and Mana Therapeutics with stock and/or ownership, is on the Board of Directors for Caballeta Bio with stock options and has stock in Neximmune and Repertoire Immune Medicines and serves on the DSMB of SOBI. MAP is on Advisory boards—Novartis, Gentibio, Bluebird, Vertex, Medexus, Equillium; and Study Support—Adaptive, Miltenyi. PJH...
PJH is a Co-founder and Board of Directors: Mana Therapeutics; and Scientific Advisory Board: Cellevolve, Cellenkos, Capsida, MicrofluidX, Discovery Life Sciences. MDK is an author for Elsevier (Uptodate), and has received research funding from Chiesi Pharmaceuticals. SC is on SAB/ Honoraria from SOBI, honoraria from Pharming P.G.T. has consulted and/or received honoraria and travel support from Illumina, Johnson and Johnson, and 10X Genomics. P.G.T. serves on the Scientific Advisory Board of Immunoscape and Cytoagents. The remaining authors declare no competing interests.
Identification and validation of a metabolism-related gene signature for predicting the prognosis of paediatric medulloblastoma.
Identification and validation of a metabolism-related gene signature for predicting the prognosis of paediatric medulloblastoma.
Fuente:Scientific Reports
Extracto:
This study could aid in identifying metabolic
targets for MB as well as optimizing risk stratification systems and individual
treatment plans for MB patients via the use of a metabolism-related gene
prognostic risk score signature.
Claves:Medulloblastoma, Metabolic-related genes, Migration and invasion, Ornithine decarboxylase
Cita:Sci Rep 2024 Mar 30; 14 (1) : 7540.
Autor/es:Su, Jun (a) Xie, Qin (b)
institución:(a) Department of Neurosurgery, The Affiliated Children's Hospital Of Xiangya School of Medicine, Central South University (Hunan children's hospital), No. 86 Ziyuan Road, Changsha, 410007, Hunan, China. (b) Department of Neurosurgery, Xiangya Hospital, Central South University, No. 86 Xiangya Road, Changsha, 410008, Hunan, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
institución:(a) Multicampi School of Medical Sciences of Rio Grande Do Norte, Federal University of Rio Grande Do Norte, Rio Grande Do Norte, Caicó, Brazil. vivianne.baptista@ufrn.br. (b) Graduate Program in Child and Adolescent Health, School of Medical Sciences, University of Campinas, Campinas, São Paulo, Brazil. vivianne.baptista@ufrn.br.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Patients' evaluation of aftercare following hospitalization for COVID-19: satisfaction and unmet needs.
Patients' evaluation of aftercare following hospitalization for COVID-19: satisfaction and unmet needs.
Fuente:Respiratory Research
Tipo de trabajo:Estudio de cohortes
Extracto:
Despite the forced quick development of COVID-19 aftercare,
patients were generally satisfied. Follow-up by healthcare professionals and
information provision is important to meet patients' aftercare needs.
Autor/es:Berentschot, Julia C (a) de Ridder, Willemijn A (b)
institución:(a) Department of Respiratory Medicine, Erasmus MC, University Medical Center Rotterdam, Dr. Molewaterplein 40, 3015 GD, Rotterdam, The Netherlands. j.berentschot@erasmusmc.nl. (b) Department of Rehabilitation Medicine, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.
Conflicto:All authors have no competing interests related to this work.
Comparative dosimetric, setup margin, and treatment time analysis between ring gantry and C-Arm linear accelerators for VMAT-based craniospinal irradiation plans.
Comparative dosimetric, setup margin, and treatment time analysis between ring gantry and C-Arm linear accelerators for VMAT-based craniospinal irradiation plans.
Fuente:Journal of Cancer Research and Therapeutics
Extracto:
Even though the majority of the
delivery parameters such as gantry speed, dose rate, beam characteristic (flatten
or unflatten), MLC width, and speed between the ring gantry HAL and C-arm NTx
linear accelerators were distinctly different, they offered no or minimal
difference in the dose distribution and in the setup margin. HAL gives a faster
treatment time delivery, which could be crucial for some selective cases such as
patients receiving treatment under general anesthesia.
Cita:J Cancer Res Ther 2024 Jan 1; 20 (1) : 224-231.
Autor/es:Biswal, Subhra S (a) Sarkar, Biplab (b)
institución:(a) Department of Radiation Oncology, Apolo Multispeciality Hospitals, Kolkata, West Bengal. (b) Depertment of Physics, GLA University, Mathura, Uttar Pradesh, India.
Biodosimetric analysis of head and neck cancer patients undergoing radiotherapy by dicentric chromosome aberration assay.
Biodosimetric analysis of head and neck cancer patients undergoing radiotherapy by dicentric chromosome aberration assay.
Fuente:Journal of Cancer Research and Therapeutics
Extracto:
There is a dose-dependent increase in the yield of DCs in lymphocytes of HNC
patients undergoing RT with subsequent fractions. Cisplatin-based chemoradiation
is the superior method of treatment intensification radio-biologically proven by
higher DC yield.
Cita:J Cancer Res Ther 2024 Jan 1; 20 (1) : 321-326.
Autor/es:Agarwal, Nayan (a) Rathi, Arun K (b)
institución:(a) Department of Radiation Oncology, Maulana Azad Medical College, New Delhi, India. (b) Department of Radiation Oncology, Maulana Azad Medical College, New Delhi, India.
Serum total oxidant and anti-oxidant status in children with cancer.
Serum total oxidant and anti-oxidant status in children with cancer.
Fuente:Journal of Cancer Research and Therapeutics
Extracto:
It has
been revealed for the first time that the serum total anti-oxidant level was high
in children undergoing chemotherapy and the survivor group as well. Moreover, the
oxidative stress index was low in children with cancer. Longitudinal prospective
studies are needed to reveal the alterations in oxidant status among children
with cancer.
Cita:J Cancer Res Ther 2024 Jan 1; 20 (1) : 369-374.
FinaleMe: Predicting DNA methylation by the fragmentation patterns of plasma cell-free DNA.
FinaleMe: Predicting DNA methylation by the fragmentation patterns of plasma cell-free DNA.
Fuente:Nature Communications
Extracto:
We validate the
performance with 80 pairs of deep and shallow-coverage whole-genome sequencing
and whole-genome bisulfite sequencing data.
Cita:Nat Commun 2024 Mar 30; 15 (1) : 2790.
Autor/es:Liu, Yaping (a) Reed, Sarah C (b)
institución:(a) Department of Biochemistry and Molecular Genetics, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA. lyping1986@gmail.com. (b) Robert H. Lurie Comprehensive Cancer Center of Northwestern University, Chicago, IL, 60611, USA. lyping1986@gmail.com.
Conflicto:Y.L., V.A.A. and M.K. have an approved patent covered FinaleMe (“Methods for genome characterization”, US Patent US11788135B2, date of patent, Oct 17, 2023, filed by MIT and Broad Institute of MIT and Harvard). Y.L. owns stocks from Freenome Inc. V.A.A., G.H. and S.F. are inventors on an approved patent covered ichorCNA (US20190078232A1, “Methods for genome characterization”, date of patent, Mar...
ent, Mar 14, 2019, filed by Harvard College, Dana Farber Cancer Institute Inc, Broad Institute of MIT and Harvard) on methods for estimating tumor fraction in cfDNA. VAA is a co-inventor on a patent application covering MAESTRO (US 2023/0203568, “Minor allele enrichment sequencing through recognition oligonucleotides”, pending, filed by Broad Institute of MIT and Harvard), which has been licensed to Exact Sciences, receives sponsored research funding from Exact Sciences, and is a cofounder and advisor to Amplifyer. The remaining authors declare no competing interests. H.Z is currently an employee at Regeneron Pharmaceuticals Inc. and contributed to this article as an employee of Cincinnati Children’s Hospital Medical Center, and the views expressed do not necessarily represent the views of Regeneron Pharmaceuticals Inc.
Supervised representation learning based on various levels of pediatric radiographic views for transfer learning.
Supervised representation learning based on various levels of pediatric radiographic views for transfer learning.
Fuente:Scientific Reports
Extracto:
Additionally, visual
analyses confirmed that the Model-PedXnets were more focused on meaningful
regions of interest.
Claves:Bone age assessment, Deep learning, Fracture classification, Pediatric radiographs, Representation learning, Transfer learning
Cita:Sci Rep 2024 Mar 30; 14 (1) : 7551.
Autor/es:Kyung, Sunggu (a) Jang, Miso (b)
institución:(a) Department of Biomedical Engineering, Asan Medical Institute of Convergence Science and Technology, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Republic of Korea. (b) Department of Convergence Medicine, Asan Medical Center, University of Ulsan College of Medicine, 88 Olympic-Ro 43-Gil, Songpa-gu, Seoul, 05505, Republic of Korea.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Lesion volume and spike frequency on EEG impact perfusion values in focal cortical dysplasia: a pediatric arterial spin labeling study.
Lesion volume and spike frequency on EEG impact perfusion values in focal cortical dysplasia: a pediatric arterial spin labeling study.
Fuente:Scientific Reports
Extracto:
These observations may facilitate the interpretation of ASL findings, improving
treatment management, counselling, and prognostication in children with
FCD-related epilepsy.
Cita:Sci Rep 2024 Mar 31; 14 (1) : 7601.
Autor/es:Gennari, Antonio Giulio (a) Bicciato, Giulio (b)
institución:(a) Department of Neuropediatrics, University Children's Hospital Zurich, 75, 8032, Zurich, Switzerland. (b) MR-Research Centre, University Children's Hospital Zurich, Zurich, Switzerland.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Assessing the risk of concurrent mycoplasma pneumoniae pneumonia in children with tracheobronchial tuberculosis: retrospective study.
Assessing the risk of concurrent mycoplasma pneumoniae pneumonia in children with tracheobronchial tuberculosis: retrospective study.
Fuente:Peerj
Extracto:
Compared to machine learning
approaches, the XGBoost model demonstrated superior predictive efficacy in
identifying pediatric patients at risk of concurrent TBTB and Mycoplasma
pneumoniae pneumonia. The model's identification of critical signatures provides
valuable insights into the pathogenesis of these conditions.
institución:(a) Department of Pediatrics, the Affiliated Changsha Central Hospital, Hengyang Medical School, University of South China, Changsha, Hunan, China. (b) Department of Pediatrics, the Affiliated Changsha Central Hospital, Hengyang Medical School, University of South China, Changsha, Hunan, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Systematic analysis of RNA-binding proteins identifies targetable therapeutic vulnerabilities in osteosarcoma.
Systematic analysis of RNA-binding proteins identifies targetable therapeutic vulnerabilities in osteosarcoma.
Fuente:Nature Communications
Extracto:
Our results thus provide insight into potentially
clinically relevant RNA-binding protein-dependent mechanisms of osteosarcoma.
Cita:Nat Commun 2024 Apr 1; 15 (1) : 2810.
Autor/es:Zhou, Yang (a) Ray, Partho Sarothi (b)
institución:(a) Molecular Medicine Partnership Unit (MMPU), Heidelberg University and European Molecular Biology Laboratory (EMBL), Heidelberg, Germany. (b) Department of Pediatric Oncology, Hematology and Immunology, Heidelberg University Hospital, Heidelberg, Germany.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
institución:(a) Sina Trauma and Surgery Research Center, Tehran University of Medical Sciences, Tehran, Iran. (b) Sina Trauma and Surgery Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Clinical phenotype and genetic function analysis of a family with hypomyelinating leukodystrophy-7 caused by POLR3A mutation.
Clinical phenotype and genetic function analysis of a family with hypomyelinating leukodystrophy-7 caused by POLR3A mutation.
Fuente:Scientific Reports
Extracto:
This study indicates that the POLR3A p.Cys767Phe variant caused
increased expression of mutated POLR3A protein and abnormal expression of Pol III
transcripts, and the mutant POLR3A protein function was abnormal.
institución:(a) Department of Traditional Chinese Medicine, Fujian Provincial Hospital, Shengli Clinical Medical College of Fujian Medical University, Fuzhou, 350001, China. (b) Department of Neurology, Fujian Medical University Union Hospital, Fuzhou, 350001, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Stabilizing time and its predictors among 1-59 months old children managed for severe acute malnutrition during the humanitarian crisis in Tigray regional state of Ethiopia, 2023
Stabilizing time and its predictors among 1-59 months old children managed for severe acute malnutrition during the humanitarian crisis in Tigray regional state of Ethiopia, 2023
Fuente:Bmc Pediatrics
Tipo de trabajo:Estudio de cohortes
Extracto:
All the
outcome indicators for stabilization center are consistent with the SPHERE
association set of standards during humanitarian intervention. The hospital and
other concerned humanitarian organizations should focus on sustaining these
achievements as suhul hospital is the main treatment center for children
suffering from severe acute malnutrition in the northwest zone of Tigray regional
state. Further pre-post experimental studies which compare the stabilizing time
before and after crisis are recommended.
Claves:Emergency, Ethiopia, Severe acute malnutrition, Stabilizing time, Tigray
Cita:BMC Pediatr 2024 Apr 1; 24 (1) : 221.
Autor/es:Tesfay, Wagnew (a) Abay, Mebrahtu (b)
institución:(a) Medical Teams International (MTI), Shire Field Office, Nutrition Supervisor, Shire, Ethiopia. wagnew.tesfaye@gmail.com. (b) College of Health Sciences, Aksum University, Aksum, Ethiopia.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Clinical features of intussusception in children secondary to small bowel tumours: a retrospective study of 31 cases.
Clinical features of intussusception in children secondary to small bowel tumours: a retrospective study of 31 cases.
Fuente:Bmc Pediatrics
Extracto:
Lymphoma is the most common cause of intussusception in
pediatric patients with small bowel tumours, followed by adenoma. Small bowel
tumours in children tend to occur in the ileum. Therefore, the treatment of SBT
patients not only requires surgeons to address symptoms through surgery and
obtain tissue samples but also relies heavily on the expertise of pathologists
for accurate diagnosis. This has a significant impact on the overall prognosis of
these patients.
Claves:Children, Intussusception, Secondary, Small bowel tumours, Surgery
Cita:BMC Pediatr 2024 Apr 1; 24 (1) : 227.
Autor/es:Wang, Li (a) Zhang, Hanwen (b)
institución:(a) Department of Emergency Surgery, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, 100045, China. (b) Department of Emergency Surgery, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, 100045, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Factors associated with damages and repair costs of reusable flexible bronchoscopes in pediatrics in China.
Factors associated with damages and repair costs of reusable flexible bronchoscopes in pediatrics in China.
Fuente:Bmc Pediatrics
Extracto:
The failure rate in the pediatric flexible bronchoscopes was not high but the
repair costs were extremely high. The types and size of the flexible
bronchoscopes and work experience of the staff members responsible for
bronchoscope reprocessing were the possible factors associated with the failure
rate in the pediatric flexible bronchoscopes. It is advisable to further optimize
the central workflow and management mode for reprocessing the pediatric flexible
bronchoscopes, thereby extending their useful life and reducing costs.
Claves:Cause analysis, Central reprocessing, Common failure, Pediatric flexible bronchoscope
Cita:BMC Pediatr 2024 Apr 1; 24 (1) : 228.
Autor/es:Hu, Ruixue (a) Chen, Yanhua (b)
institución:(a) Department of Sterile Processing Nursing, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, China. (b) Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education, Chengdu, Sichuan, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación