Outcomes post Ozaki procedure among children with aortic valve disease at Jakaya Kikwete Cardiac Institute, Dar es Salaam, Tanzania: a retrospective descriptive study.

Outcomes post Ozaki procedure among children with aortic valve disease at Jakaya Kikwete Cardiac Institute, Dar es Salaam, Tanzania: a retrospective descriptive study.

Fuente:Bmc Cardiovascular Disorders

Tipo de trabajo:Revisión

Extracto: Ozaki procedure showed encouraging early results among children with aortic valve disease who underwent surgical repair by this technique. Future studies with larger sample sizes and longer follow up periods to evaluate long-term results in this population are recommended.

Claves:Aortic valve, Ozaki procedure, Paediatrics, Tanzania

Cita:BMC Cardiovasc Disord 2024 Mar 19; 24 (1) : 163.

Autor/es:Kalezi, Zawadi Edward (a)
Simbila, Alphonce Nsabi (b)

institución:(a) Department of Paediatric cardiology, Jakaya Kikwete Cardiac Institute, P.O Box 65141, Dar es Salaam, Tanzania. ezawadi8@gmail.com.
(b) Emergency Medicine Department, Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12872-024-03829-8

Benzodiazepine use in medical cannabis authorization adult patients from 2013 to 2021: Alberta, Canada.

Benzodiazepine use in medical cannabis authorization adult patients from 2013 to 2021: Alberta, Canada.

Fuente:Bmc Public Health

Tipo de trabajo:Estudio de cohortes

Extracto: This short-term study found that medical cannabis authorization had minimal effects on benzodiazepine use. Our findings may contribute ongoing evidence for clinicians regarding the potential impact of medical cannabis to reduce benzodiazepine use. HIGHLIGHTS: • Medical cannabis authorization had little to no effect on benzodiazepine usage among patients prescribed regular benzodiazepine treatment in Alberta, Canada. • Further clinical research is needed to investigate the potential impact of medical cannabis as an alternative to benzodiazepine medication.

Claves:Anxiety, Benzodiazepine, Cohort study, Diazepam equivalence, Epidemiology, Medical cannabis

Cita:BMC Public Health 2024 Mar 20; 24 (1) : 859.

Autor/es:Dubois, Cerina (a)
Fernandes, Heidi (b)

institución:(a) School of Public Health, University of Alberta, 3-300 Edmonton Clinic Health Academy 11405 - 87 Ave Edmonton, AB, T6G 1C9 2E, Edmonton, AB, Canada.
(b) School of Public Health, University of Alberta, 3-300 Edmonton Clinic Health Academy 11405 - 87 Ave Edmonton, AB, T6G 1C9 2E, Edmonton, AB, Canada.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12889-024-18356-6

Transplantation: platform to study recurrence of disease.

Transplantation: platform to study recurrence of disease.

Fuente:Frontiers in Immunology

Extracto: Our team has been studying these phenomena and their immunologic underpinnings, and we suggest that expanding the concept to other pathologic processes and/or transplanted organs that harbor the risk for recurrent disease may provide novel insight into the pathogenesis of a host of other disease processes that lead to organ failure.

Claves:cytokines, kidney transplant, liver transplant, pancreas transplant, recurrent disease

Cita:Front Immunol 2024; 15 : 1354101.

Autor/es:Burke, George William (a)
Mitrofanova, Alla (b)

institución:(a) Division of Kidney-Pancreas Transplantation, Department of Surgery, Miami Transplant Institute, University of Miami Miller School of Medicine, Miami, FL, United States.
(b) Katz Family Division of Nephrology and Hypertension, Department of Medicine, University of Miami Miller School of Medicine, Miami, FL, United States.

Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3389/fimmu.2024.1354101

Metabolic control level and glucose variability in adolescents with type 1 diabetes during low and high-intensity exercise.

Metabolic control level and glucose variability in adolescents with type 1 diabetes during low and high-intensity exercise.

Fuente:European Review For Medical and Pharmacological Sciences

Extracto: HbA1c levels are insufficient to confirm whether the applied effort is performed in acceptable glycemic values. The CGM monitors allow for precise control of BG variations and accurate planning of physical activity by adjusting the insulin and carbohydrate consumption dose.

Cita:Eur Rev Med Pharmacol Sci 2024 Mar; 28 (5) : 1987-1997.

Autor/es:Skalska, M (a)
Myśliwiec, A (b)

institución:Skalska, M (a)
Myśliwiec, A (b)

Formato:Informe impreso

Idioma:Inglés

País de fuente:Italia

Sitio web:http://dx.doi.org/10.26355/eurrev_202403_35613

Association between Parvovirus B19 and thyroid/celiac autoantibodies among T1DM pediatric patients.

Fuente:European Review For Medical and Pharmacological Sciences

Extracto: The prevalence of autoantibodies against the thyroid was higher among the seropositive Parvovirus B19 children with T1DM. A positive association between the prevalence of autoantibodies against thyroid disease and the increase in the duration of diabetes was also noted. Hence, periodic screening of T1DM patients for B19 antibodies and autoantibodies for thyroid is crucial.

Cita:Eur Rev Med Pharmacol Sci 2024 Mar; 28 (5) : 1998-2004.

Autor/es:Chandramoorthy, H C (a)
Shati, A A (b)

institución:Chandramoorthy, H C (a)
Shati, A A (b)

Formato:Informe impreso

Idioma:Inglés

País de fuente:Italia

Sitio web:http://dx.doi.org/10.26355/eurrev_202403_35614

COVID-19 Computed tomography patterns in renal replacement therapy patients.

COVID-19 Computed tomography patterns in renal replacement therapy patients.

Fuente:Jornal Brasileiro de Nefrologia

Extracto: In hospitalized ESKD patients on RRT, atypical chest CT pattern cannot adequately rule out the diagnosis of COVID-19.

Cita:J Bras Nefrol 2024 Jul-Sep; 46 (3) : e20230029.

Autor/es:Carmo, Gabriel Assis Lopes do (a)
Oliveira, Mariana Paiva (b)

institución:(a) Hospital Evangélico de Belo Horizonte, Belo Horizonte, MG, Brazil.
(b) Universidade Federal de Minas Gerais, Faculdade de Medicina, Departamento de Clínica Médica, Belo Horizonte, MG, Brazil.

Formato:Informe impreso

Idioma:eng, por

País de fuente:Brasil

Sitio web:http://dx.doi.org/10.1590/2175-8239-JBN-2023-0029en

CVOT Summit Report 2023: new cardiovascular, kidney, and metabolic outcomes.

CVOT Summit Report 2023: new cardiovascular, kidney, and metabolic outcomes.

Fuente:Cardiovascular Diabetology

Tipo de trabajo:Guía

Extracto: The 10th Cardiovascular Outcome Trial Summit will be held virtually on December 5-6, 2024 ( http://www.cvot.org ).

Claves:CGM, Cardiovascular disease, Chronic kidney disease, Diabetes, Finerenone, GLP-1 RA, Guidelines, Heart failure, MASLD, NAFLD, Obesity, SGLT2 inhibitor, Teplizumab

Cita:Cardiovasc Diabetol 2024 Mar 19; 23 (1) : 104.

Autor/es:Schnell, Oliver (a)
Barnard-Kelly, Katharine (b)

institución:(a) Forschergruppe Diabetes e. V, Helmholtz Center Munich, Ingolstaedter Landstraße 1, 85764, Neuherberg (Munich), Germany. oliver.schnell@lrz.uni-muenchen.de.
(b) Southern Health NHS Foundation Trust, Southampton, United Kingdom.

Conflicto:OS (Oliver Schnell) is the founder and CEO of Sciarc and reports consulting, speaking, or serving on advisory boards for AstraZeneca, Bayer, Boehringer Ingelheim, Lilly, MSD, Mundipharma, Novo Nordisk, Roche, Sanofi, and Wörwag Pharma. KBK (Katharine Barnard-Kelly) is founder and shareholder at Spotlight-AQ Ltd. KBK has received research support from Dexcom, Embecta, JDRF, Novo Nordisk and Roche Diabetes Care, and... d honoraria from Sanofi. TB (Tadej Battelino) has served on the advisory boards of Abbott, Boehringer Ingelheim, Dreamed Diabetes, Eli Lilly and Company, Indigo Diabetes, Medtronic, Novo Nordisk, and Sanofi. TB has received speaker’s bureau honoraria from Abbott, Eli Lilly and Company, Medtronic, Novo Nordisk, Roche, and Sanofi. The University Medical Center has received research grant support from Abbott, GluSense, Medtronic, Novo Nordisk, Sandoz, Sanofi, and Zealand Pharma. AC (Antonio Ceriello) reports consulting and speaking for Bayer, Berlin-Chemie, Eli Lilly and Company, Guidotti, Merck, Novo Nordisk, Roche Diagnostics and Sanofi. HEL (Helena Elding Larsson) declares that she has no competing interests. BFF (Beatriz Fernández-Fernández) has received grants from AstraZeneca and Esteve and consultancy or speaker fees or travel support from Amgen, AstraZeneca, Bayer, Boehringer Ingelheim, Eli Lilly and Company, Menarini, Novo Nordisk, and Mundipharma. JPF (Juan-Pablo Frias) is employee and stockholder of Biomea Fusion, Inc. JPF has received research support from Akero, Altimmune, Boehringer Ingelheim, 89bio, Eli Lilly and Company, Intercept, IONIS, Janssen, Madrigal, Merck, NorthSea Therapeutics, Novartis, Novo Nordisk, Oramed, Pfizer, Sanofi, and Shionogi. JPF has also served as a consultant and on the advisory boards of Akero, Altimmune, Biomea Fusion, Boehringer Ingelheim, Carmot Therapeutics, Echosens, 89bio, Eli Lilly and Company, Gilead, Intercept, Metacrine, Merck, Novo Nordisk, Pfizer, Sanofi, and on the speaker’s bureau for Eli Lilly and Company. TF (Thomas Forst) has been a member of the speaker panel of Amarin, AstraZeneca, Boehringer Ingelheim, Berlin-Chemie, Cipla, Daiichi-Sankyo, Eli Lilly and Company, Fortbildungskolleg, MSD, Novartis, Novo Nordisk, Sanofi, Santis, and of the advisory panel of Atrogi, Bayer, Cipla, Diabetes-Akademie Bad Mergentheim e.V., Eli Lilly and Company, Eyesense, Fortbildungskolleg, Novo Nordisk, Pfizer, reMYND, Roche and Sanofi. JRG (James R. Gavin III) has served on the advisory boards of Abbott Diabetes Care and Embecta, and on the speaker’s bureaus of Boehringer Ingelheim and Eli Lilly and Company. FG (Francesco Giorgino) has served on the advisory boards of AstraZeneca, Eli Lilly and Company, Novo Nordisk, Roche Diabetes Care, Sanofi and as a consultant to AstraZeneca, Boehringer Ingelheim, LifeScan, Medimmune, Medtronic, Merck Sharp & Dohme, Roche Diabetes Care and Sanofi. FG has also received research support from Eli Lilly and Company and Roche Diabetes Care. PHG (Per-Henrik Groop) has received lecture honoraria from Astellas, AstraZeneca, Bayer, Boehringer Ingelheim, Eli Lilly and Company, EloWater, Genzyme, Medscape, MSD, Mundipharma, Novartis, Novo Nordisk, Peer Voice, Sanofi and Sciarc. PHG also serves as an advisory board member for AbbVie, Astellas, AstraZeneca, Bayer, Boehringer Ingelheim, Eli Lilly and Company, Medscape, MSD, Mundipharma, Novartis, Novo Nordisk, and Sanofi. HJLH (Hiddo J.L. Heerspink) declares that he has no competing interests. SH (Stephan Herzig) declares that he has no competing interests. MH (Michael Hummel) declares that he has no competing interests. GH (George Huntley) declares that he has no competing interests. MI (Mahmoud Ibrahim) has consultancy agreement with and received speaker honoraria from Boehringer Ingelheim, Medtronic, Novo Nordisk, and Pfizer. BI (Baruch Itzhak) has received honoraria or consulting fees from AstraZeneca, Boehringer Ingelheim, Eli Lilly and Company, and Novo Nordisk and speaking fees from Abbott, Amgen, AstraZeneca, Boehringer Ingelheim, Eli Lilly and Company, Novo Nordisk, Roche, and Sanofi. SJ (Stephan Jacob) declares that he has no competing interests. LJ (Linong Ji) declares that he has no competing interests. MK (Mikhail Kosiborod) reports consulting or advisory board participation for 35Pharma, Alnylam Pharmaceuticals, Amgen, Applied Therapeutics, AstraZeneca, Bayer, Boehringer Ingelheim, Cytokinetics, Dexcom, Eli Lilly and Company, Esperion Therapeutics, Janssen Pharmaceuticals, Lexicon Pharmaceuticals, Merck (Diabetes and Cardiovascular), Novo Nordisk, Pharmacosmos, Pfizer, scPharmaceuticals, Sanofi, Structure Therapeutics, Vifor Pharma and Youngene Therapeutics. MK has also received honoraria from AstraZeneca, Boehringer Ingelheim and Novo Nordisk, and research grants from AstraZeneca, Boehringer Ingelheim and Pfizer. NL (Nebosja Lalic) declares that he has no competing interests. SM (Sofia Macieira) is employee of Sciarc. RM (Rayaz A. Malik) has served on the advisory panel and received honoraria for speaking for Eli Lilly and Company, Novo Nordisk, Proctor & Gamble, Sanofi Aventis, and Viatris. RM has also received research funding for studies from Novo Nordisk and Proctor & Gamble. BM (Boris Mankovsky) has served on advisory boards and received speaking fees from AstraZeneca, Bayer, Boehringer Ingelheim, Novartis, Novo Nordisk, Sanofi, Servier, and Wörwag Pharma. NM (Nikolaus Marx) has received research grants from Boehringer Ingelheim and MSD, speaking fees form Amgen, AstraZeneca, Bayer, BMS, Boehringer Ingelheim, Eli Lilly and Company, MSD, Novo Nordisk, and Sanofi-Aventis and has served or serves on the advisory board of Amgen, Bayer, BMS, Boehringer Ingelheim, MSD, Novo Nordisk, and Sanofi-Aventis. CM (Chantal Mathieu) serves or has served on the advisory panel for ActoBio Therapeutics, Avotres, AstraZeneca, Boehringer Ingelheim, Eli Lilly and Company, Imcyse, Insulet, Mannkind, Medtronic, Merck Sharp and Dohme Ltd., Novartis, Novo Nordisk, Pfizer, Sandoz, Sanofi, Roche, Vertex and Zealand Pharma. CM serves or has served on the speakers’ bureau for AstraZeneca, Boehringer Ingelheim, Eli Lilly and Company, Novartis Novo Nordisk, and Sanofi. Financial compensation for these activities has been received by KU Leuven. KU Leuven has received research support for CM from ActoBio Therapeutics, Imcyse, Medtronic, Novo Nordisk, and Sanofi. TM (Timo Müller) reports having received honoraria or research support from AstraZeneca, Berlin-Chemie, Eli Lilly and Company, Merck, Mercodia, MSD, Novo Nordisk, and Sanofi Aventis in the past 3 years. KR (Kausik Ray) has served as a consultant for Abbott, Amarin, Amgen, AstraZeneca, Bayer, Boehringer Ingelheim, Cargene Therapeutics, Cleerly Health, CRISPR Therapeutics, CSL Behring, Eli Lilly and Company, EmendoBio, Esperion Therapeutics, Kowa Pharmaceutics, New Amsterdam Pharma, Novartis, Novo Nordisk, Pfizer, Regeneron, Resverlogix, Sanofi, Scribe Thearapeutics, Silence Therapeutics, VAXXINITY, and Viatris. KR reports having received research grants from Amgen, Daiichi Sankyo, MSD, Pfizer, Regeneron, Sanofi and Ultragenix. HR (Helena W. Rodbard) declares that she has no competing interests. PR (Peter Rossing) has received honoraria for consultancy and/or speaking fees (to his institution) from AstraZeneca, Bayer, Boehringer Ingelheim, Eli Lilly and Company, Gilead, MSD, Novo Nordisk, and Sanofi Aventis and research grants from AstraZeneca, Bayer, and Novo Nordisk. LR (Lars Rydén) declares that he has no competing interests. PMSD (Petra-Maria Schumm-Draeger) declares that she has no competing interests. PS (Peter Schwarz) declares that he has no competing interests. JS (Jan Škrha) declares that he has no competing interests. FS (Frank Snoek) has received research support from Sanofi, consulting fees from Abbott, LifeScan, Roche, and Sanofi, and has served on a speaker’s bureau for Abbott and Sanofi. FT (Frank Tacke) declares that work in his lab has been supported by research grants from AstraZeneca, Gilead, and MSD. BT (Bruce Taylor) is employee of Dexcom. BTJ (Britta Tendal Jeppesen) declares that she has no competing interests. ST (Solomon Tesfaye) reports honoraria for educational meetings from Astellas Pharma, AstraZeneca, Berlin-Chemie, Eva Pharma, Grünenthal, Hikma, Merck, Nevro, Novo Nordisk, P&G Health, Viatris, and Wörwag Pharma; consulting fees from Angelini, AstraZeneca, Bayer, Grünenthal, Mitsubishi Tanabe Pharma, Merz, NeuroPN, Nevro, Viatris and Wörwag Pharma; unrestricted research grants from Proctor and Gamble, Viatris and Withings. PT (Pinar Topsever) has received honoraria or consulting fees from AstraZeneca, Boehringer Ingelheim, Eli Lilly and Company, and LifeScan, and has served on the speaker’s bureau for AstraZeneca. PT received grant/research support from PCDE, made possible by corporate sponsorship from AstraZeneca, Eli Lilly, Novo Nordisk, and Roche Diagnostics; the sponsors had no input into the study protocols. TV (Tina Vilsbøll) has served on scientific advisory panels, been part of speaker’s bureaus, and served as a consultant to and/or received research support from Amgen, AstraZeneca, Boehringer Ingelheim, Eli Lilly and Company, Gilead, GSK, Mundipharma, MSD/Merck, Novo Nordisk, Sanofi, and Sun Pharmaceuticals. XY (Xuefeng Yu) declares that he has no competing interests. ES (Eberhard Standl) declares that he has no competing interests.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12933-024-02180-8

Assessment of hepatic fibrosis with non-invasive indices in subjects with diabetes before and after liver transplantation.

Assessment of hepatic fibrosis with non-invasive indices in subjects with diabetes before and after liver transplantation.

Fuente:Frontiers in Endocrinology

Extracto: DISCUSSION: Thus, persistence of diabetes after surgery is a possible risk factor for an evolution to fibrosis in the transplanted liver, potentially leading to worsened long-term outcomes in this population.

Claves:APRI score, FIB-4, diabetes mellitus, fibrosis, liver transplantation

Cita:Front Endocrinol (Lausanne) 2024; 15 : 1359960.

Autor/es:Grancini, Valeria (a)
Cogliati, Irene (b)

institución:(a) Endocrinology Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
(b) Endocrinology Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.

Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3389/fendo.2024.1359960

Priority-setting for hospital funding of high-cost innovative drugs and therapeutics: A qualitative institutional case study.

Priority-setting for hospital funding of high-cost innovative drugs and therapeutics: A qualitative institutional case study.

Fuente:Plos One

Extracto: This study identifies values and processes to aid in the development and implementation of institutional resource allocation frameworks for high-cost innovative D&Ts.

Cita:PLoS One 2024; 19 (3) : e0300519.

Autor/es:Razvi, Yasmeen (a)
Horwitz, Simonne L (b)

institución:(a) Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada.
(b) SickKids Research Institute, Child Health Evaluative Sciences, Toronto, ON, Canada.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1371/journal.pone.0300519

Clinical Characteristics, Etiology, and Outcomes of Hypothermia in Well-appearing Children Referred to the Emergency Department.

Fuente:The Israel Medical Association Journal Imaj

Extracto: There is a low incidence of SBI in well-appearing children presenting to the PED with hypothermia and a benign course and outcome in those older than 3 months.

Cita:Isr Med Assoc J 2024 Mar; 26 (3) : 157-161.

Autor/es:Ohana Sarna, Lea (a)
Qaraen Saloni, Dina (b)

institución:(a) Department of Pediatrics, Hadassah Medical Center, Hebrew University of Jerusalem, Jerusalem, Israel.
(b) Department of Pediatrics, Hadassah Medical Center, Hebrew University of Jerusalem, Jerusalem, Israel.

Formato:Informe impreso

Idioma:Inglés

País de fuente:Israel

Sitio web:

Women´s experiences of menopause: A qualitative study among women in Soweto, South Africa.

Fuente:Global Public Health

Extracto: Recognising how women may perceive menopause not as a deficit or disorder but as a social role transition that has both costs and benefits is useful for medical practitioners when discussing clinical options.

Claves:Menopause, aging, culture, medicalisation, postmenopause

Cita:Glob Public Health 2024 Jan; 19 (1) : 2326013.

Autor/es:Matina, Sostina Spiwe (a)
Mendenhall, Emily (b)

institución:(a) SA MRC/Wits Developmental Pathways for Health Research Unit, Department of Paediatrics, Faculty of Health Sciences, School of Clinical Medicine, University of the Witwatersrand, Johannesburg, South Africa.
(b) SA MRC/Wits Developmental Pathways for Health Research Unit, Department of Paediatrics, Faculty of Health Sciences, School of Clinical Medicine, University of the Witwatersrand, Johannesburg, South Africa.

Formato:Informe impreso

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1080/17441692.2024.2326013

Aberrant DNA methylation distorts developmental trajectories in atypical teratoid/rhabdoid tumors.

Fuente:Life Science Alliance

Extracto: These results highlight and characterize the role of DNA hypermethylation in AT/RT malignancy and halted neural cell differentiation.

Cita:Life Sci Alliance 2024 Jun; 7 (6)

Autor/es:Pekkarinen, Meeri (a)
Nordfors, Kristiina (b)

institución:(a) https://ror.org/033003e23 Prostate Cancer Research Center, Faculty of Medicine and Health Technology, Tampere University and Tays Cancer Center, Tampere University Hospital, Tampere, Finland.
(b) https://ror.org/033003e23 Tampere Center for Child Health Research, Tays Cancer Center, Tampere University and Tampere University Hospital, Tampere, Finland.

Conflicto:The authors declare that they have no conflict of interest.

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.26508/lsa.202302088

Protocol for the diagnostic performance of C reactive protein, procalcitonin and interleukin-6 for serious bacterial infections among children ?36 months old presenting with fever without source

Fuente:Bmj Paediatrics Open

Tipo de trabajo:Revisión sistemática

Extracto: PROSPERO REGISTRATION NUMBER: CRD42023439093.

Claves:Biochemistry, Infant, Microbiology

Cita:BMJ Paediatr Open 2024 Mar 18; 8 (1)

Autor/es:Sutiman, Natalia (a)
Yao, Sarah Hui Wen (b)

institución:(a) Department of Emergency Medicine, Kandang Kerbau Women's and Children's Hospital, Singapore natalia.sutiman@mohh.com.sg.
(b) Kandang Kerbau Women's and Children's Hospital, Singapore.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1136/bmjpo-2023-002237

Y-box binding protein 1 in small extracellular vesicles reduces mesenchymal stem cell differentiation to osteoblasts-implications for acute myeloid leukaemia.

Fuente:Journal of Extracellular Vesicles

Extracto: Altogether, our data demonstrate for the first time that YBX1 containing AML-sEVs is one of the key players that disrupt the normal function of bone marrow microenvironment by reducing the osteogenic differentiation of BM-MSCs.

Claves:Y-box binding protein 1, acute myeloid leukaemia, bone marrow microenvironment, mesenchymal stem cells, osteoblasts, small extracellular vesicles

Cita:J Extracell Vesicles 2024 Mar; 13 (3) : e12417.

Autor/es:Chetty, Venkatesh Kumar (a)
Ghanam, Jamal (b)

institución:(a) Department of Pediatrics III, University Hospital Essen, Essen, Germany.
(b) Department of Pediatrics III, University Hospital Essen, Essen, Germany.

Conflicto:The authors report no conflict of interest.

Formato:Informe impreso

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1002/jev2.12417

Time to recovery and its predictors following traumatic injuries among injured victims in Dessie Comprehensive Specialized Hospital, North East of Ethiopia, 2022: a retrospective follow-up study.

Fuente:Bmc Emergency Medicine

Tipo de trabajo:Revisión

Extracto: The median recovery time for traumatically injured respondents was 5 days. Independent predictors such as the Glasgow coma scale, time taken for surgical management, intent of injury, and traumatic brain injury were statistically significant with time to recovery from trauma.

Claves:Associated factor, Injury, Predictor, Recovery, Time, Trauma

Cita:BMC Emerg Med 2024 Mar 18; 24 (1) : 44.

Autor/es:Tilahun, Lehulu (a)
Zeleke, Mulusew (b)

institución:(a) College of Medicine and Health Sciences, Department of Emergency and Ophthalmic Nursing, Wollo University, PO Box 1145, Dessie, Ethiopia. lehulut333@gmail.com.
(b) College of Medicine and Health Sciences, Department of Adult Health Nursing, Wollo University, Dessie, Ethiopia.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12873-024-00960-9

The Freiburg Acuity Test in Preschool Children: Testability, Test-Retest Variability, and Comparison With LEA Symbols.

Fuente:Translational Vision Science & Technology

Extracto: The examiner-independent FrACT, using international reference Landolt C optotypes, can be used to assess VA in preschool children aged ≥4 years, with reliability comparable to other pediatric VA tests. TRANSLATIONAL RELEVANCE: Use of the automated FrACT for VA assessment in preschool children may benefit objectivity and validity as it is a computerized test and employs the international reference Landolt C optotype.

Cita:Transl Vis Sci Technol 2024 Mar 1; 13 (3) : 14.

Autor/es:Farassat, Navid (a)
Jehle, Vanessa (b)

institución:(a) Eye Center, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
(b) https://orcid.org/0000-0002-4409-2176.

Formato:Informe impreso

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1167/tvst.13.3.14

A deep-learning workflow to predict upper tract urothelial carcinoma protein-based subtypes from H&E slides supporting the prioritization of patients for molecular testing.

Fuente:The Journal of Pathology. Clinical Research

Extracto: Taken together, our DL workflow can predict protein-based UTUC subtypes, associated with the presence of targetable alterations, directly from H&E slides.

Claves:deep-learning, digital pathology, immunohistochemistry, protein-based subtypes, targeted therapy, upper tract urothelial carcinoma, whole slide images

Cita:J Pathol Clin Res 2024 Mar; 10 (2) : e12369.

Autor/es:Angeloni, Miriam (a)
van Doeveren, Thomas (b)

institución:(a) Institute of Pathology, University Hospital Erlangen-Nürnberg, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany.
(b) Comprehensive Cancer Center Erlangen-EMN (CCC ER-EMN), Erlangen, Germany.

Formato:Informe impreso

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1002/2056-4538.12369

Development and implementation of digital peer mentoring in small groups for first-year medical students.

Fuente:Gms Journal For Medical Education

Extracto: The implementation of PM was successful and beneficial for the participating students. PM can help first-year medical students reduce anxiety, improve self-organization and orientation at university. It fosters identity formation and has positive effects on peer mentees as well as on peer mentors.

Claves:digital mentoring, first year medical students, many-to-many, one-to-many, peer mentoring, professional identity formation, student mentors

Cita:GMS J Med Educ 2024; 41 (1) : Doc11.

Autor/es:Drossard, Sabine (a)
Härtl, Anja (b)

institución:(a) University Hospital Augsburg, Department of Pediatric Surgery, Augsburg, Germany.
(b) University Hospital Würzburg, Department of General, Visceral, Transplant, Vascular and Pediatric Surgery, Würzburg, Germany.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Alemania

Sitio web:http://dx.doi.org/10.3205/zma001666

Multidisciplinary Simulation for Blunt and Penetrating Pediatric Trauma Utilizing Standard and Rapid Cycle Deliberate Practice Models.

Fuente:Mededportal The Journal of Teaching and Learning Resources

Extracto: DISCUSSION: Multidisciplinary team practice of pediatric trauma scenarios, particularly utilizing the RCDP simulation model, provides the opportunity to improve teamwork and communication, practice procedural skills, and deepen team members' understanding of and comfort with trauma resuscitations.

Claves:Clinical/Procedural Skills Training, Emergency Medicine, Pediatric Emergency Medicine, Pediatrics, Rapid Cycle Deliberate Practice, Simulation, Surgery - General, Surgery - Pediatric, Trauma

Cita:MedEdPORTAL 2024; 20 : 11390.

Autor/es:Henkel, Erin B (a)
Lemke, Daniel (b)

institución:(a) Assistant Professor, Department of Pediatrics, Baylor College of Medicine; Associate Trauma Medical Director, Division of Pediatric Emergency Medicine, Texas Children's Hospital.
(b) Associate Professor, Division of Pediatric Emergency Medicine, Department of Pediatrics, Baylor College of Medicine; Associate Medical Director of Simulation Center, Texas Children's Hospital.

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.15766/mep_2374-8265.11390

Relationship between exercise habits and physical function in children aged 9-12 years.

Fuente:Nagoya Journal of Medical Science

Extracto: In conclusion, exercise regardless of exercise level for at least 30 min per day, 2 days per week, for at least 1 year is important for skeletal muscle mass and instantaneous lower limb muscular strength development in school-aged children.

Claves:children, exercise habits, physical function, skeletal muscle mass index

Cita:Nagoya J Med Sci 2024 Feb; 86 (1) : 24-35.

Autor/es:Takahashi, Daiki (a)
Ito, Tadashi (b)

institución:(a) Department of Integrated Health Sciences, Nagoya University Graduate School of Medicine, Nagoya, Japan.
(b) Department of Integrated Health Sciences, Nagoya University Graduate School of Medicine, Nagoya, Japan.

Conflicto:The authors declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

Formato:Informe impreso

Idioma:Inglés

País de fuente:Japón

Sitio web:http://dx.doi.org/10.18999/nagjms.86.1.24