Bone marrow mesenchymal stem cell-derived exosomes shuttle microRNAs to endometrial stromal fibroblasts that promote tissue proliferation /regeneration/ and inhibit differentiation.

Fuente:Stem Cell Research & Therapy

Extracto: EVs delivered to tissues by hBMDSCs contain specific miRNAs that prevent terminal differentiation and drive repair and regeneration. Delivery of microRNAs is a novel treatment paradigm with the potential to replace BMDSCs in cell-free regenerative therapies.

Claves:BMDSCs, Decidualization, Exosomes, eSF, miRNAs

Cita:Stem Cell Res Ther 2024 May 1; 15 (1) : 129.

Autor/es:Bonavina, Giulia (a)
Mamillapalli, Ramanaiah (b)

institución:(a) Department of Obstetrics, Gynecology and Reproductive Sciences, Yale School of Medicine, 310 Cedar Street, 06510, New Haven, CT, USA.
(b) IRCCS San Raffaele Scientific Institute, Milan, Italy.

Conflicto:All authors declare no competing interests.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s13287-024-03716-1

Lack of Diversity in Research on Females with Ehlers-Danlos Syndromes: Recruitment Protocol for a Quantitative Online Survey.

Fuente:Jmir Research Protocols

Extracto: Our recruitment method was successful at recruiting a large sample. The sample was predominantly White and from North America and Europe. More research needs to be conducted on how to recruit a diverse sample. Areas to investigate may include connecting with more support groups from outside the United States and Europe, researching which platforms are popular in different countries, and translating study materials into different languages. A larger obstacle to recruiting diverse samples may be the lack of health care providers that diagnose EDS outside the United States and Europe, making the pool of potential participants small. There needs to be more health care providers that diagnose and treat EDS in countries that are predominantly made up of people of color as well as research that specifically focuses on these populations. INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID): RR1-10.2196/53646.

Claves:Ehlers-Danlos syndrome, Facebook, United States, challenges, connective tissue disorders, cross-sectional survey, diversity, dyspareunia, ethnic, hereditary disease, hypermobility, information seeking, online, painful sex, racial, recruitment, social media, strategies, strategy

Cita:JMIR Res Protoc 2024 May 2; 13 : e53646.

Autor/es:Glayzer, Jennifer E (a)
Bray, Bethany C (b)

institución:(a) Department of Human Development Nursing Science, College of Nursing, University of Illinois Chicago, Chicago, IL, United States.
(b) Institute for Health Research and Policy, University of Illinois Chicago, Chicago, IL, United States.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Canadá

Sitio web:http://dx.doi.org/10.2196/53646

PSFHS: Intrapartum ultrasound image dataset for AI-based segmentation of pubic symphysis and fetal head.

Fuente:Scientific Data

Extracto: Remarkably, this dataset stands as the most expansive and comprehensive resource for PSFHS to date.

Cita:Sci Data 2024 May 2; 11 (1) : 436.

Autor/es:Chen, Gaowen (a)
Bai, Jieyun (b)

institución:(a) Obstetrics and Gynecology Center, Zhujiang Hospital, Southern Medical University, Guangzhou, China.
(b) Department of Electronic Engineering, College of Information Science and Technology, Jinan University, Guangzhou, China. jbai996@aucklanduni.ac.nz.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1038/s41597-024-03266-4

Emergency cesarean section of a patient with refractory status epilepticus

Fuente:Medicine

Tipo de trabajo:Caso clínico

Extracto: Inducing anesthesia in pregnant women with ongoing seizure activity are challenging; however, anesthesiologists provide judgment based on the balance between the safety of the mother and fetus and the balance between patient monitoring and the progression of anesthesia. This challenge can be addressed through multidisciplinary collaboration.

Cita:Medicine (Baltimore) 2024 May 3; 103 (18) : e37988.

Autor/es:Park, Jin Soo (a)
Chung, Jin Hun (b)

institución:Park, Jin Soo (a)
Chung, Jin Hun (b)

Conflicto:The authors have no funding and conflicts of interest to disclose.

Formato:Informe impreso

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1097/MD.0000000000037988

Value of 2D speckle tracking technique combined with real-time 3-dimensional echocardiography in the evaluation of the right atrial function in patients with 3-branch coronary artery disease without myocardial infarction.

Fuente:Medicine

Extracto: The storage, conduit, and pump functions of the right atrium are reduced in patients with 3-branch coronary artery disease without myocardial infarction; 2D-STE combined with RT-3DE is valuable in the evaluation of the right atrium in patients with coronary artery disease.

Cita:Medicine (Baltimore) 2024 May 3; 103 (18) : e38058.

Autor/es:Zhang, Siran (a)
Zhou, Qiao (b)

institución:(a) Department of Ultrasound, the Second Hospital of Dalian Medical University, Dalian, Liaoning Province, China.
(b) Department of Obstetrics and Gynecology Ultrasound, the Second Hospital of Dalian Medical University, Dalian, Liaoning Province, China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe impreso

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1097/MD.0000000000038058

Travel burdens to access care among children with cancer between 2016 and 2019: Analysis of a national population-based cancer registry in Japan.

Travel burdens to access care among children with cancer between 2016 and 2019: Analysis of a national population-based cancer registry in Japan.

Fuente:Plos One

Extracto: Most patients were treated in specialized hospitals and the treatments for specific diseases were centralized. However, most patients were estimated to travel less than 1 h, and the travel burden tended to increase for patients in rural areas, those with specific diseases, and those going to specialized hospitals. Cancer control measures in Japan have steadily improved centralized treatment while keeping the travel burden relatively manageable.

Cita:PLoS One 2024; 19 (4) : e0300840.

Autor/es:Tsutsui, Anna (a)
Murakami, Yoshitaka (b)

institución:(a) Department of Medical Statistics, School of Medicine, Toho University, Tokyo, Japan.
(b) Department of Mathematical Health Science, Graduate School of Medicine, Osaka University, Suita, Osaka, Japan.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1371/journal.pone.0300840

Dyadic care to improve postnatal outcomes of birthing people and their infants

Fuente:Plos One

Tipo de trabajo:Revisión

Extracto: TRAIL REGISTRATION: This review has been registered at Open Science Framework (OSF, https://osf.io/5fs6e/).

Cita:PLoS One 2024; 19 (4) : e0298927.

Autor/es:Choy, Courtney C (a)
McAdow, Molly E (b)

institución:(a) Department of Chronic Disease Epidemiology, Yale School of Public Health, New Haven, Connecticut, United States of America.
(b) Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale School of Medicine, New Haven, Connecticut, United States of America.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1371/journal.pone.0298927

Male perspectives on intimate partner violence: A qualitative analysis from South Africa.

Fuente:Plos One

Extracto: Interventions aimed at reducing IPV should consider the cultural and social impact on men's use of IPV in low-resource, high-IPV prevalence settings, such as peri-urban South Africa. This work highlights the persistent need for the implementation of effective primary prevention strategies that address contextual and economic factors in an effort to reduce IPV that is primarily utilized by men directed at women.

Cita:PLoS One 2024; 19 (4) : e0298198.

Autor/es:Pelowich, Krysta A (a)
Akibu, Tosin (b)

institución:(a) School of Public Health, Brown University, Providence, Rhode Island, United States of America.
(b) Department of Community Health Sciences, Fielding School of Public Health, University of California, Los Angeles, Los Angeles, California, United States of America.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1371/journal.pone.0298198

Epidemiology of congenital heart defects in France from 2013 to 2022 using the PMSI-MCO (French Medical Information System Program in Medicine, Surgery, and Obstetrics) database.

Fuente:Plos One

Extracto: According to the PMSI-MCO database, the incidence of congenital heart defects in France from 2013 to 2022 is 1% of births. Congenital heart defects are more frequent in cases of prematurity, twinning, primiparity, male sex, and maternal age > 40 years.

Cita:PLoS One 2024; 19 (4) : e0298234.

Autor/es:Bourdon, Gurvan (a)
Lenne, Xavier (b)

institución:(a) Maternity Unit, Department of Gynecology and Obstetrics, Lille University Hospital, Lille, France.
(b) Department of Medical Information, Lille University Hospital, Lille, France.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1371/journal.pone.0298234

Perioperative outcomes and causes of postpartum hemorrhage in patients undergoing cesarean delivery in Thailand: A comprehensive retrospective study.

Fuente:Plos One

Tipo de trabajo:Estudio clínico

Extracto: These findings highlight the importance of comprehensive perioperative management strategies, including the ready availability of adequate blood and blood products, particularly in scenarios predisposed to significant hemorrhage. TRIAL REGISTRATION: Clinical trial registration: Clinicaltrial.gov registration number NCT04833556 (April 6, 2021).

Cita:PLoS One 2024; 19 (4) : e0300620.

Autor/es:Nivatpumin, Patchareya (a)
Nithi-Uthai, Jitsupa (b)

institución:(a) Faculty of Medicine Siriraj Hospital, Department of Anesthesiology, Mahidol University, Bangkok, Thailand.
(b) Faculty of Medicine Siriraj Hospital, Department of Anesthesiology, Mahidol University, Bangkok, Thailand.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1371/journal.pone.0300620

Dimensions of patient-centred care from the perspective of patients and healthcare workers in hospital settings in sub-Saharan Africa: A qualitative evidence synthesis.

Fuente:Plos One

Tipo de trabajo:Revisión sistemática

Extracto: The conceptualization of PCC within SSA was largely similar to findings from other parts of the world, although with a stronger emphasis on access to care. In SSA, both relational and structural aspects of care were significant elements of PCC. Healthcare providers mostly perceived structural aspects such as infrastructure as key dimensions of PCC. TRIAL REGISTRATION: PROSPERO Registration number CRD42021238411.

Cita:PLoS One 2024; 19 (4) : e0299627.

Autor/es:Okeny, Paul K (a)
Pittalis, Chiara (b)

institución:(a) Institute of Global Surgery, School of Population Health, RCSI University of Medicine and Health Sciences, Dublin, Ireland.
(b) Department of Surgery, School of Medicine, Makerere University College of Health Sciences, Kampala, Uganda.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1371/journal.pone.0299627

Achieving optimal cord management: a multidisciplinary quality improvement initiative.

Fuente:Bmj Open Quality

Extracto: It also highlights the importance of national benchmarking data in allowing departments to focus QIP efforts to achieve long-lasting transformational service improvements.

Claves:Clinical Audit, Quality improvement, Quality improvement methodologies

Cita:BMJ Open Qual 2024 Apr 15; 13 (2)

Autor/es:Burgess-Shannon, Jessica (a)
Clarke, Rebecca (b)

institución:(a) Neonatal Unit, Homerton University Hospital NHS Foundation Trust, London, UK.
(b) Neonatal Unit, Homerton University Hospital NHS Foundation Trust, London, UK.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1136/bmjoq-2023-002662

Cost-effectiveness of a radio intervention to stimulate early childhood development: protocol for an economic evaluation of the SUNRISE trial in Burkina Faso.

Cost-effectiveness of a radio intervention to stimulate early childhood development: protocol for an economic evaluation of the SUNRISE trial in Burkina Faso.

Fuente:Bmj Open

Tipo de trabajo:Estudio aleatorizado y controlado

Extracto: TRIAL REGISTRATION NUMBER: The SUNRISE trial was registered with ClinicalTrials.gov on 19 April 2019 (identifier: NCT05335395).

Claves:Behavior, Community child health, HEALTH ECONOMICS

Cita:BMJ Open 2024 Apr 16; 14 (4) : e080905.

Autor/es:Palmer, Tom (a)
Clare, Abbie (b)

institución:(a) University College London, London, UK t.palmer@ucl.ac.uk.
(b) Development Media International, London, UK.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1136/bmjopen-2023-080905

Imaging for local recurrence of breast cancer.

Imaging for local recurrence of breast cancer.

Fuente:Journal of Cancer Research and Clinical Oncology

Extracto: In breast cancer survivors, MRI might improve the early detection of ILRR and CBC in both HBOC and nHBOC patients.

Claves:Contralateral breast cancer, Hereditary breast cancer, Imaging methods, Isolated locoregional recurrence

Cita:J Cancer Res Clin Oncol 2024 Apr 17; 150 (4) : 200.

Autor/es:Schlaiss, T (a)
Bott, L (b)

institución:(a) Department of Gynaecology and Obstetrics, University Hospital Würzburg, Josef-Schneider-Str. 4, 97080, Würzburg, Germany. Schlaiss_T@ukw.de.
(b) Department of Gynaecology and Obstetrics, University Hospital Würzburg, Josef-Schneider-Str. 4, 97080, Würzburg, Germany.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Alemania

Sitio web:http://dx.doi.org/10.1007/s00432-024-05709-2

Aerobic vaginitis is associated with carbonic anhydrase IX in cervical intraepithelial neoplasia.

Aerobic vaginitis is associated with carbonic anhydrase IX in cervical intraepithelial neoplasia.

Fuente:Scientific Reports

Extracto: Regression model revealed that msAV associated with high-grade cervical intraepithelial neoplasia independently from smoking and the number of partners.

Claves:Aerobic vaginitis, CAIX enzyme, Carbonic anhydrase 9, Cervical intraepithelial neoplasia, Microbiota alteration, Uterine cervix dysplasia

Cita:Sci Rep 2024 Apr 16; 14 (1) : 8789.

Autor/es:Grincevičienė, Švitrigailė (a)
Vaitkienė, Daiva (b)

institución:(a) Department of Biothermodynamics and Drug Design, Institute of Biotechnology, Life Sciences Center, Vilnius University, Sauletekio Av. 7, 10257, Vilnius, Lithuania. svitrigaile.grinceviciene@bti.vu.lt.
(b) Department of Obstetrics and Gynecology, Medical Academy, Lithuanian University of Health Sciences, Eiveniu St. 2, 50161, Kaunas, Lithuania.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1038/s41598-024-57427-x

The impact of CREBRF rs373863828 Pacific-variant on infant body composition.

Fuente:Scientific Reports

Extracto: However, this association was not significant after adjustment for gestational diabetes, suggesting that it may be mediated, at least in part, by the beneficial effect of CREBRF rs373863828 A allele on maternal glycemic status.

Cita:Sci Rep 2024 Apr 17; 14 (1) : 8825.

Autor/es:Amitrano, Francesca (a)
Krishnan, Mohanraj (b)

institución:(a) Liggins Institute, University of Auckland, Auckland, New Zealand.
(b) Department of Obstetrics and Gynaecology, University of Auckland, Auckland, New Zealand.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1038/s41598-024-59417-5

Diagnoses of obstetric and postpartum thyroid disease: a Danish validation study.

Fuente:Scientific Reports

Extracto: A high validity was seen for PPT (O905) and obstetric hypothyroidism (O992B), whereas for obstetric hyperthyroidism (O992C), the diagnosis could not be verified in one third of the cases.

Cita:Sci Rep 2024 Apr 16; 14 (1) : 8777.

Autor/es:Houmøller, Anne Myrup (a)
Gerlif, Katrine (b)

institución:(a) Department of Clinical Biochemistry, Aalborg University Hospital, 9000, Aalborg, Denmark.
(b) Department of Clinical Biochemistry, Aalborg University Hospital, 9000, Aalborg, Denmark.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1038/s41598-024-59636-w

Continuing the conversation: a cross-sectional study about the effects of work-related adverse events on the mental health of Dutch (resident) obstetrician-gynaecologists (ObGyns).

Continuing the conversation: a cross-sectional study about the effects of work-related adverse events on the mental health of Dutch (resident) obstetrician-gynaecologists (ObGyns).

Fuente:Bmc Psychiatry

Extracto: The percentages of anxiety, depression, psychological distress and PTSD are comparable to the similar study performed in 2014. Most Dutch ObGyns experience adverse events at work, which can be perceived as traumatic and, in certain cases, may lead to the development of PTSD. Structured support after adverse work-related events is now available in almost two-thirds of workplaces, and was mostly experienced as good. Despite substantial improvements in the availability and satisfaction of professional support after work-related adverse events, the prevalence rates of mental problems remain considerable, and it is imperative to sustain conversation about the mental well-being of ObGyns.

Claves:Adverse event, ObGyns, PTSD, Second victim, Trauma

Cita:BMC Psychiatry 2024 Apr 16; 24 (1) : 286.

Autor/es:Baas, Melanie A M (a)
Stramrood, Claire A I (b)

institución:(a) Department of Obstetrics and Gynaecology, OLVG, 1090 HM, Amsterdam, PO box 95500, The Netherlands.
(b) Department of Obstetrics and Gynaecology, University Medical Center Groningen, 9700 RB, Groningen, PO box 30.001, The Netherlands.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12888-024-05678-3

Development and validation of the Cannabis Exposure in Pregnancy Tool (CEPT): a mixed methods study.

Development and validation of the Cannabis Exposure in Pregnancy Tool (CEPT): a mixed methods study.

Fuente:Bmc Pregnancy and Childbirth

Extracto: The CEPT is a novel, valid and reliable measure of frequency, timing, dose, and mode of PCU, in a contemporary sample of pregnant women. Using CEPT (compared to non-standardized tools) can improve measurement accuracy, and thus the quality of research examining PCU and maternal and child health outcomes.

Claves:Cannabis, Marijuana, Measurement, Pregnancy, Prenatal, Reliability, Validity

Cita:BMC Pregnancy Childbirth 2024 Apr 16; 24 (1) : 280.

Autor/es:Chaput, Kathleen H (a)
McMorris, Carly A (b)

institución:(a) Department of Obstetrics and Gynecology, Cumming School of Medicine, University of Calgary, 2500 Unievrsity Drive NW, Calgary, AB, Canada. khchaput@ucalgary.ca.
(b) Department of Community Health Sciences, Cumming School of Medicine University of Calgary, 1403 29 Street NW, Calgary, AB, T2N 2T9, Canada. khchaput@ucalgary.ca.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12884-024-06485-0

Integration of single-cell RNA-seq and bulk RNA-seq data to construct and validate a cancer-associated fibroblast-related prognostic signature for patients with ovarian cancer.

Integration of single-cell RNA-seq and bulk RNA-seq data to construct and validate a cancer-associated fibroblast-related prognostic signature for patients with ovarian cancer.

Fuente:Journal of Ovarian Research

Extracto: The study highlights the importance of CAFs in OC progression and suggests potential for innovative treatment strategies. A CAF-based risk signature provides a highly accurate prediction of the prognosis of OC patients, and the developed nomogram shows promising results in predicting the OC prognosis.

Claves:Cancer-associated fibroblasts, Immune therapy, Ovarian cancer, Tumor microenvironment

Cita:J Ovarian Res 2024 Apr 16; 17 (1) : 82.

Autor/es:Shen, Liang (a)
Li, Aihua (b)

institución:(a) Department of Obstetrics and Gynecology, Liaocheng People's Hospital, 67 Dongchang West Road, Liaocheng, Shandong, 252000, P.R. China.
(b) Shandong University, Jinan, P.R. China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s13048-024-01399-z