Substance P Concentration in Gestational Diabetes and Excessive Gestational Weight Gain and Its Impact on Neonatal Anthropometry.

Substance P Concentration in Gestational Diabetes and Excessive Gestational Weight Gain and Its Impact on Neonatal Anthropometry.

Fuente:International Journal of Molecular Sciences

Extracto: To our knowledge, it is the first study assessing substance P concentration in GDM and EGWG patients.

Claves:excessive gestational weight gain, fetal programming, gestational diabetes mellitus, substance P

Cita:Int J Mol Sci 2024 Mar 28; 25 (7)

Autor/es:Niebrzydowska-Tatus, Magdalena (a)
Pełech, Aleksandra (b)

institución:(a) Chair and Department of Obstetrics and Perinatology, Medical University of Lublin, 20-090 Lublin, Poland.
(b) Chair and Department of Obstetrics and Perinatology, Medical University of Lublin, 20-090 Lublin, Poland.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3390/ijms25073759

TCF7L2 Polymorphism rs7903146 (C/T) and Gestational Diabetes Influence on Obstetric Outcome: A Romanian Case-Control Study.

Fuente:International Journal of Molecular Sciences

Extracto: The presence of at least one minor T allele was associated with a higher risk of fetal macrosomia.

Claves:TCF7L2 gene, fetal macrosomia, gestational diabetes mellitus, rs7903146 (C/T) polymorphism

Cita:Int J Mol Sci 2024 Apr 4; 25 (7)

Autor/es:Cruciat, Gheorghe (a)
Florian, Andreea Roxana (b)

institución:(a) Mother and Child Department, Obstetrics and Gynecology I, "Iuliu Haţieganu" University of Medicine and Pharmacy Cluj-Napoca, 400347 Cluj-Napoca, Romania.
(b) Mother and Child Department, Obstetrics and Gynecology I, "Iuliu Haţieganu" University of Medicine and Pharmacy Cluj-Napoca, 400347 Cluj-Napoca, Romania.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3390/ijms25074039

Inflammatory Dietary Potential Is Associated with Vitamin Depletion and Gut Microbial Dysbiosis in Early Pregnancy.

Inflammatory Dietary Potential Is Associated with Vitamin Depletion and Gut Microbial Dysbiosis in Early Pregnancy.

Fuente:Nutrients

Extracto: Dietary inflammatory potential was associated with a reduction in the consumption of vitamins and minerals and predicted gut microbiota metabolic dysregulation.

Claves:diet, dietary inflammatory index, food frequency questionnaire, galactose, gut microbiota, inflammation, pregnancy

Cita:Nutrients 2024 Mar 24; 16 (7)

Autor/es:Alvernaz, Suzanne A (a)
Wenzel, Elizabeth S (b)

institución:(a) Department of Biomedical Engineering, University of Illinois, Chicago, IL 60607, USA.
(b) Department of Psychology, University of Illinois, Chicago, IL 60607, USA.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3390/nu16070935

Food Cravings and Obesity in Women with Polycystic Ovary Syndrome: Pathophysiological and Therapeutic Considerations.

Fuente:Nutrients

Extracto: Cognitive-behavioral intervention seems to be the mainstay of treatment, while the role of medical agents, such as GLP-1 analogs and naltrexone/bupropion, has emerged.

Claves:binge eating, food cravings, food disorders, obesity, polycystic ovary syndrome

Cita:Nutrients 2024 Apr 3; 16 (7)

Autor/es:Stefanaki, Katerina (a)
Karagiannakis, Dimitrios S (b)

institución:(a) Endocrine Unit and Diabetes Center, Department of Clinical Therapeutics, Alexandra Hospital, School of Medicine, National and Kapodistrian University of Athens, 11527 Athens, Greece.
(b) Academic Department of Gastroenterology, Laiko General Hospital, School of Medicine, National and Kapodistrian University of Athens, 11527 Athens, Greece.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3390/nu16071049

Early prediction of gestational diabetes mellitus using maternal demographic and clinical risk factors.

Early prediction of gestational diabetes mellitus using maternal demographic and clinical risk factors.

Fuente:Bmc Research Notes

Extracto: While the performance markedly decreased to an AUC of 0.69 when testing the MMC-based model on the external nuMoM2b test data, close to the performance trained and tested on the nuMoM2b dataset only (AUC = 0.70).

Claves:Clinical risk factors, Early prediction, Gestational diabetes mellitus, Maternal demographics, Model validation

Cita:BMC Res Notes 2024 Apr 15; 17 (1) : 105.

Autor/es:Wu, Yanqi (a)
Hamelmann, Paul (b)

institución:(a) Department of Electrical Engineering, Eindhoven University of Technology, Eindhoven, The Netherlands.
(b) Philips Research, Eindhoven, The Netherlands.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s13104-024-06758-z

Circadian Gene Variants: Effects in Overweight and Obese Pregnant Women.

Circadian Gene Variants: Effects in Overweight and Obese Pregnant Women.

Fuente:International Journal of Molecular Sciences

Extracto: These data suggest a potential role of the polymorphisms in clock systems and in fat taste perception in both susceptibility to overweight/obesity and influencing the related metabolic traits in pregnant women.

Claves:BMAL1, CD36, CLOCK, GDM, Mediterranean diet, obesity, pregnancy

Cita:Int J Mol Sci 2024 Mar 29; 25 (7)

Autor/es:Franzago, Marica (a)
Borrelli, Paola (b)

institución:(a) Department of Medicine and Aging, School of Medicine, and Health Sciences, "G. D'Annunzio" University, Via dei Vestini, Chieti-Pescara, 66100 Chieti, Italy.
(b) Center for Advanced Studies and Technology (CAST), "G. D'Annunzio" University, Chieti-Pescara, 66100 Chieti, Italy.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3390/ijms25073838

Minerals and the Menstrual Cycle: Impacts on Ovulation and Endometrial Health.

Minerals and the Menstrual Cycle: Impacts on Ovulation and Endometrial Health.

Fuente:Nutrients

Tipo de trabajo:Revisión

Extracto: This review stands as the first to offer such a detailed examination of minerals in the context of the menstrual cycle, aiming to elevate the understanding of their critical role in female fertility and reproductive health.

Claves:endometrial health, fertility, menstrual cycle, minerals, ovulation

Cita:Nutrients 2024 Mar 29; 16 (7)

Autor/es:Kapper, Celine (a)
Oppelt, Peter (b)

institución:(a) Experimental Gynaecology, Obstetrics and Gynaecological Endocrinology, Johannes Kepler University Linz, Altenberger Strasse 69, 4040 Linz, Austria.
(b) Experimental Gynaecology, Obstetrics and Gynaecological Endocrinology, Johannes Kepler University Linz, Altenberger Strasse 69, 4040 Linz, Austria.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3390/nu16071008

Association between Daily Dietary Calcium Intake and the Risk of Cardiovascular Disease (CVD) in Postmenopausal Korean Women.

Fuente:Nutrients

Extracto: Our findings suggest that a dietary calcium intake of >800 mg/day decreases the risk of CVD events in women who have been menopausal for >10 years.

Claves:Korea national health and nutrition examination survey (KNHANES), cardiovascular diseases, cross-sectional study, dietary calcium intake, menopause, postmenopausal women

Cita:Nutrients 2024 Apr 3; 16 (7)

Autor/es:Lee, Jae Kyung (a)
Tran, Thi Minh Chau (b)

institución:(a) Department of Obstetrics and Gynecology, Severance Hospital, Yonsei College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul 03722, Republic of Korea.
(b) Department of Obstetrics and Gynecology, Tu Du Hospital, University of Medicine and Pharmacy, Ho Chi Minh City 700000, Vietnam.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3390/nu16071043

Hypertension, Cardiovascular Risk Factors, and Uterine Fibroid Diagnosis in Midlife.

Hypertension, Cardiovascular Risk Factors, and Uterine Fibroid Diagnosis in Midlife.

Fuente:Jama Network Open

Tipo de trabajo:Estudio de cohortes

Extracto: AND RELEVANCE: Participants with untreated and new-onset hypertension had increased risk of newly diagnosed fibroids, whereas those taking antihypertensive treatment had lower risk, suggesting that blood pressure control may provide new strategies for fibroid prevention.

Cita:JAMA Netw Open 2024 Apr 1; 7 (4) : e246832.

Autor/es:Mitro, Susanna D (a)
Wise, Lauren A (b)

institución:(a) Division of Research, Kaiser Permanente Northern California, Oakland.
(b) Department of Epidemiology, Boston University School of Public Health, Boston, Massachusetts.

Conflicto:Conflict of Interest Disclosures: Dr Wise reported receiving grants from the National Institutes of Health (NIH), personal fees from The Gates Foundation and Abbvie, Inc, and in-kind donations for primary data collection in a study outside the submitted work from Swiss Precision Diagnostics (home pregnancy tests) and Kindara.com (fertility applications). Dr Waetjen reported receiving grants from Accessa Health Inc outside... the submitted work. Dr Solomon reported receiving grants from CorEvitas, Janssen, and Novartis outside the submitted work. Dr Thurston reported receiving personal fees from Astellas Pharma, Bayer, Hello Therapeutics, Happify Health, and Vira Health outside the submitted work. Dr Santoro reported receiving grants from Menogenix, Inc, and personal fees from Astellas Pharma, Ansh Labs, Amazon, and FertilityIQ outside the submitted work. No other disclosures were reported.

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1001/jamanetworkopen.2024.6832

Genetic Researchers' Use of and Interest in Research With Diverse Ancestral Groups.

Fuente:Jama Network Open

Extracto: AND RELEVANCE: In this survey study of US genetic researchers, respondents reported existing databases only provide adequate ancestral samples for European populations, despite their interest in other ancestral populations. These findings suggest there are specific gaps in access to and composition of genetic databases, highlighting the urgent need to boost diversity in research samples to improve inclusivity in genetic research practices.

Cita:JAMA Netw Open 2024 Apr 1; 7 (4) : e246805.

Autor/es:Jaffe, Kaitlyn (a)
Greene, Amanda K (b)

institución:(a) Department of Health Promotion and Policy, University of Massachusetts, Amherst.
(b) Center for Bioethics and Social Sciences in Medicine, University of Michigan Medical School, Ann Arbor.

Conflicto:Conflict of Interest Disclosures: Dr McGuire reported receiving personal fees from Geisinger Research, Morgridge Institute for Research, Danaher, Greenwall Foundation Board, and Nature Genomics outside the submitted work. No other disclosures were reported.

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1001/jamanetworkopen.2024.6805

Efficient CAR T cell targeting of the CA125 extracellular repeat domain of MUC16.

Fuente:Journal For Immunotherapy of Cancer

Extracto: Our in vitro and in vivo results, including PDX studies, demonstrate that the CA125 domain of MUC16 represents an excellent target for treating MUC16-positive malignancies.

Claves:T-lymphocytes, immunotherapy, receptors, chimeric antigen

Cita:J Immunother Cancer 2024 Apr 11; 12 (4)

Autor/es:Casey, Nicholas P (a)
Kleinmanns, Katrin (b)

institución:(a) Translational Research Unit, Section of Cellular Therapy, Department of Oncology, Oslo University Hospital, Oslo, Norway.
(b) Centre for Cancer Biomarkers CCBIO, Department of Clinical Science, University of Bergen, Bergen, Norway.

Conflicto:Competing interests: SW, EMI, DJW, NPC and EB have filled a patent application on chimeric antigen receptor for ovarian cancer. The other authors declare no conflict of interest.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1136/jitc-2023-008179

A statistical investigation of parameters associated with low cell-free fetal DNA fraction in maternal plasma for noninvasive prenatal testing.

Fuente:The Journal of Maternal-fetal & Neonatal Medicine The Official Journal of The European Association of Perinatal Medicine, The Federation of Asia and Oceania Perinatal Societies, The International Society of Perinatal Obstetricians

Extracto: According to our findings based on the OR value, factors associated strongly with LFF include a high BMI and the use of IVF. Factors associated less strongly with LFF include early gestational age and twin pregnancy, while advanced maternal age and IVF were independent risk factors for a second LFF result.

Claves:Noninvasive prenatal testing, body mass index, gestational age, in vitro fertilization, low fetal fraction, maternal age

Cita:J Matern Fetal Neonatal Med 2024 Dec; 37 (1) : 2338440.

Autor/es:Pan, Yun (a)
Pan, Xiaoli (b)

institución:(a) The Central Laboratory of Birth Defects Prevention and Control, Women and Children's Hospital of Ningbo University, Ningbo, China.
(b) Ningbo Key Laboratory for the Prevention and Treatment of Embryogenic Diseases, Women and Children's Hospital of Ningbo University, Ningbo, China.

Formato:Informe impreso

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1080/14767058.2024.2338440

Endometrial stem cells alleviate cisplatin-induced ferroptosis of granulosa cells by regulating Nrf2 expression.

Fuente:Reproductive Biology and Endocrinology Rb&e

Extracto: Our study demonstrated that cisplatin could induce ferroptosis in granulosa cells, while EnSCs could inhibit ferroptosis and thus exert repair effects on the cisplatin-induced injury model both in vivo and in vitro. Meanwhile, Nrf2 was validated to participate in this regulatory process and played an essential role.

Claves:Endometrial stem cells, Ferroptosis, Ferrostatin-1, Nrf2, Premature ovarian failure

Cita:Reprod Biol Endocrinol 2024 Apr 11; 22 (1) : 41.

Autor/es:Pan, Rumeng (a)
Wang, Rongli (b)

institución:(a) Department of Obstetrics and Gynecology, The First Affiliated Hospital of Xi'an Jiaotong University, 710061, Xi'an, China.
(b) Department of Obstetrics and Gynecology, The First Affiliated Hospital of Xi'an Jiaotong University, 710061, Xi'an, China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12958-024-01208-8

Outcomes after fertility-sparing surgery of early-stage ovarian cancer: A nationwide population-based study.

Fuente:Cancer Medicine

Extracto: FSS can be a safe alternative procedure in selected young patients of Stage I EOC who have fertility desire. Endometrial biopsy before or during FSS and regular surveillance to detect recurrence are mandatory for ovarian cancer patients undergoing FSS.

Claves:fertility‐sparing surgery, outcome, ovarian cancer, population study, staging surgery, survival

Cita:Cancer Med 2024 Apr; 13 (7) : e7132.

Autor/es:Lee, Chia-Yi (a)
Chiang, Chun-Ju (b)

institución:(a) Department of Obstetrics and Gynecology, National Taiwan University Hospital, Hsin-Chu Branch, Hsinchu, Taiwan.
(b) Department of Obstetrics and Gynecology, National Taiwan University Hospital, Taipei, Taiwan.

Conflicto:No potential conflicts of interest were disclosed.

Formato:Informe impreso

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1002/cam4.7132

A giant ovarian cyst torsion

Fuente:Medicine

Tipo de trabajo:Caso clínico

Extracto: Giant ovarian cyst torsion with a diameter of 30 cm is rare. Considering her symptoms and examination, ultrasound, and MRI results, ovarian cyst torsion was suspected. The patient was successfully treated using emergency surgery.

Cita:Medicine (Baltimore) 2024 Apr 12; 103 (15) : e33283.

Autor/es:Giant ovarian cyst torsion with a diameter of 30 cm is rare. Considering her symptoms and examination, ultrasound, and MRI results, ovarian cyst torsion was suspected. The patient was successfully treated using emergency surgery.

institución:Giant ovarian cyst torsion with a diameter of 30 cm is rare. Considering her symptoms and examination, ultrasound, and MRI results, ovarian cyst torsion was suspected. The patient was successfully treated using emergency surgery.

Conflicto:The authors have no funding and conflicts of interest to disclose.

Formato:Informe impreso

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1097/MD.0000000000033283

Experiences of women with gestational diabetes about fear of having diabetes in their babies: A qualitative study.

Fuente:Medicine

Extracto: More qualitative studies are needed to learn more about the experiences of women with gestational diabetes in endocrine clinics.

Cita:Medicine (Baltimore) 2024 Apr 12; 103 (15) : e37755.

Autor/es:Topaloğlu Ören, Ekin Dila (a)
Ünsal Avdal, Elif (b)

institución:(a) Izmir Katip Celebi University Faculty of Health Science, Department of Obstetrics and Gynecology Nursing, İzmir, Türkiye.
(b) Izmir Katip Celebi University Faculty of Health Science, Department of Internal Medicine Nursing, İzmir, Türkiye.

Conflicto:The authors have no funding and conflicts of interest to disclose.

Formato:Informe impreso

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1097/MD.0000000000037755

The influencing factors of changes in physical activity levels of pregnant women during pregnancy: From the perspective of continuous care.

Fuente:Medicine

Extracto: Medical personnel should improve the living habits of pregnant women and enhance their PAL through measures such as health education and psychological counseling.

Cita:Medicine (Baltimore) 2024 Apr 12; 103 (15) : e37575.

Autor/es:Liu, Meng (a)
Huang, Wenxia (b)

institución:(a) Department of Obstetrics Nursing, West China Second University Hospital, Sichuan University/Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Chengdu, Sichuan, China.
(b) Department of Health Management Center, West China Hospital, Sichuan University, Chengdu, Sichuan, China.

Conflicto:JW and WH contributed equally to this work.The authors have no funding and conflicts of interest to disclose.

Formato:Informe impreso

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1097/MD.0000000000037575

Nanobiotechnology augmented cancer stem cell guided management of cancer: liquid-biopsy, imaging, and treatment.

Fuente:Journal of Nanobiotechnology

Extracto: Specifically, how nanobiotechnologies leverage the attributes of CSC to maximize the detection of circulating tumor DNA, circulating tumor cells, and exosomes, to improve positron emission computed tomography and magnetic resonance imaging, and to enhance the therapeutic effects of cytotoxic therapy, photodynamic therapy, immunotherapy therapy, and radioimmunotherapy are reviewed.

Claves:Cancer stem cell, Circulating tumor DNA, Liquid biopsy, Molecular imaging, Nanobiotechnology, Nuclear medicine

Cita:J Nanobiotechnology 2024 Apr 12; 22 (1) : 176.

Autor/es:Sun, Si (a)
Yang, Qiang (b)

institución:(a) Department of Obstetrics and Gynecology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.
(b) Department of Obstetrics and Gynecology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12951-024-02432-5

Using Computer Vision to Annotate Video-Recoded Direct Observation of Physical Behavior.

Fuente:Sensors (basel, Switzerland)

Extracto: Future research should test these machine learning models on larger, independent datasets and take advantage of analysis of video fragments, rather than individual still images.

Claves:assessment, computer vision, direct observation, physical activity, sedentary behavior

Cita:Sensors (Basel) 2024 Apr 8; 24 (7)

Autor/es:Keadle, Sarah K (a)
Eglowski, Skylar (b)

institución:(a) Department of Kinesiology and Public Health, California Polytechnic State University, San Luis Obispo, CA 93407, USA.
(b) Sentimetrix Inc., Bethesda, MD 20814, USA.

Conflicto:The funders had no role in the design of the study; in the collection, analyses, or interpretation of data; in the writing of the manuscript; or in the decision to publish the results. Authors Mr. Kagan and Mx. Eglowski are employed by the company SentiMetrix Inc. The remaining authors declare that the research was conducted in the absence of any... commercial or financial relationships that could be construed as a potential conflict of interest.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3390/s24072359

Application of interpretable machine learning algorithms to predict distant metastasis in ovarian clear cell carcinoma.

Fuente:Cancer Medicine

Extracto: This study successfully established a precise predictive model for OCCC patient metastasis using machine learning techniques, offering valuable support to clinicians in making informed clinical decisions.

Claves:SEER, machine learning, metastasis, ovarian clear cell carcinoma

Cita:Cancer Med 2024 Apr; 13 (7) : e7161.

Autor/es:Guo, Qin-Hua (a)
Xie, Feng-Chun (b)

institución:(a) Jiangxi Province Key Laboratory of Laboratory Medicine, Jiangxi Provincial Clinical Research Center for Laboratory Medicine, Department of Clinical Laboratory, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi, China.
(b) Department of Clinical Laboratory, The First Hospital of Nanchang (The Third Affiliated Hospital of Nanchang University), Nanchang, Jiangxi, China.

Conflicto:No potential conflict of interest was reported by the authors.

Formato:Informe impreso

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1002/cam4.7161