The effect of task load, information reliability and interdependency on anticipation performance.

Fuente:Cognitive Research: Principles and Implications

Extracto: Findings suggest that updating anticipatory judgements in the final phase of a sequence of play based on the integration of reliable contextual and kinematic information requires cognitive resources.

Claves:Cognitive load, Contextual information, Kinematic information, Perceptual-cognitive expertise, Sport

Cita:Cogn Res Princ Implic 2024 Apr 14; 9 (1) : 22.

Autor/es:Murphy, Colm P (a)
Runswick, Oliver R (b)

institución:(a) Cardiff School of Sport and Health Sciences, Cardiff Metropolitan University, Cardiff, CF23 6XD, UK. cmurphy2@cardiffmet.ac.uk.
(b) Faculty of Sport, Technology and Health Sciences, St. Mary's University, Twickenham, UK. cmurphy2@cardiffmet.ac.uk.

Conflicto:The authors declare having no known conflict of interests.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s41235-024-00548-8

Cholesterol metabolism in tumor microenvironment: cancer hallmarks and therapeutic opportunities.

Fuente:International Journal of Biological Sciences

Extracto: Finally, we outline the unresolved questions and suggest potential avenues for future investigations on cholesterol metabolism in relation to cancer.

Claves:antitumor immunity, cholesterol homeostasis, drug repurposing, metastasis, statin, tumor microenvironment

Cita:Int J Biol Sci 2024; 20 (6) : 2044-2071.

Autor/es:Jiang, Wen (a)
Jin, Wei-Lin (b)

institución:(a) Department of General Surgery, The First Affiliated Hospital of Anhui Medical University, Hefei 230022, P. R. China.
(b) Institute of Cancer Neuroscience, Medical Frontier Innovation Research Center, The First Hospital of Lanzhou University, Lanzhou 730000, P. R. China.

Conflicto:Competing Interests: The authors have declared that no competing interest exists.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Australia

Sitio web:http://dx.doi.org/10.7150/ijbs.92274

Myoclonus and Dystonia as Recurrent Presenting Features in Patients with the SCA21-Associated TMEM240 p.Pro170Leu Variant.

Fuente:Tremor and Other Hyperkinetic Movements (new York, N.y.)

Tipo de trabajo:Revisión

Extracto: TMEM240 mutation should be included in the differential diagnosis of myoclonic dystonia and ataxia-dystonia syndromes.

Claves:Dystonia, Myoclonus, Pro170Leu, SCA21, Spinocerebellar ataxia, TMEM240

Cita:Tremor Other Hyperkinet Mov (N Y) 2024; 14 : 16.

Autor/es:Sorrentino, Ugo (a)
Romito, Luigi M (b)

institución:(a) Clinical Genetics Unit, Department of Women's and Children's Health, University of Padova, Padova, Italy.
(b) Institute of Neurogenomics, Helmholtz Munich, Neuherberg, Germany.

Conflicto:The authors have no competing interests to declare.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.5334/tohm.858

Dancing Out of Step: A Case of Tuberculous Meningitis Presenting as Childhood Chorea.

Fuente:Tremor and Other Hyperkinetic Movements (new York, N.y.)

Tipo de trabajo:Revisión

Extracto: DISCUSSION: We review the mechanisms in tuberculous meningitis underlying his movement abnormalities.

Claves:TB meningitis, chorea, tuberculous meningitis

Cita:Tremor Other Hyperkinet Mov (N Y) 2024; 14 : 17.

Autor/es:Garcia, Jao Jarro B (a)
Tecson-Delos Santos, Cherie Marie A (b)

institución:(a) Division of Adult Neurology, Department of Neurosciences, College of Medicine and Philippine General Hospital, University of the Philippines Manila, Manila, Philippines.
(b) Division of Pediatric Neurology, Department of Neurosciences, College of Medicine and Philippine General Hospital, University of the Philippines Manila, Manila, Philippines.

Conflicto:The authors have no competing interests to declare.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.5334/tohm.871

The First Case of Huntington's Disease like 2 in Mali, West Africa.

Fuente:Tremor and Other Hyperkinetic Movements (new York, N.y.)

Extracto: HIGHLIGHTS: We report here the first case of HDL2 in West Africa, suggesting that HDL2 is widely spread across African continent, and increasing access to genetic testing could uncover other cases.

Claves:HDL2, JPH3, Mali, West Africa

Cita:Tremor Other Hyperkinet Mov (N Y) 2024; 14 : 15.

Autor/es:Bocoum, Abdoulaye (a)
Ouologuem, Madani (b)

institución:(a) Facultéde Médecine et d'Odontostomatologie, USTTB, Bamako, Mali.
(b) Service de Médecine, Hôpital du Mali, Bamako, Mali.

Conflicto:The authors have no competing interests to declare.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.5334/tohm.859

Preventing Shift from Pneumocephalus During Deep Brain Stimulation Surgery: Don't Give Up the 'Fork in the Brain'.

Fuente:Tremor and Other Hyperkinetic Movements (new York, N.y.)

Extracto: The recognition that the removal of a guide-tube cannula could worsen brain shift creates an opportunity for an intraoperative team to maintain the advantage of the 'fork' in the brain provided by the initial procedure's requirement of guide-tube placement.

Claves:Deep brain stimulation, brain shift, intra-operative, microelectrode recording, pneumocephalus

Cita:Tremor Other Hyperkinet Mov (N Y) 2024; 14 : 18.

Autor/es:Martinez-Nunez, Alfonso Enrique (a)
Wong, Joshua K (b)

institución:(a) Departments of Neurology and Neurosurgery, Norman Fixel Institute for Neurological Disease, University of Florida, Gainesville, FL, US.
(b) Departments of Neurology and Neurosurgery, Norman Fixel Institute for Neurological Disease, University of Florida, Gainesville, FL, US.

Conflicto:The authors have no competing interests to declare.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.5334/tohm.873

Von Hippel Lindau tumor suppressor controls m6A-dependent gene expression in renal tumorigenesis.

Fuente:The Journal of Clinical Investigation

Extracto: Taken together, we propose a mechanism by which VHL regulates m6A through modulation of METTL3/METTL14 complex formation, thereby promoting PIK3R3 mRNA stability and protein levels that are critical for regulating ccRCC tumorigenesis.

Claves:Oncology, Tumor suppressors

Cita:J Clin Invest 2024 Apr 15; 134 (8)

Autor/es:Zhang, Cheng (a)
Yu, Miaomiao (b)

institución:(a) Department of Pathology, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
(b) Department of Pathology, University of Texas Southwestern Medical Center, Dallas, Texas, USA.

Conflicto:Conflict of interest: QZ received the consultation fee from Exelixis.

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1172/JCI175703

Histological analysis of the dermal and hypodermal layers of the face and correlation with high-frequency 24 MHz ultrasonography and elastosonography.

Fuente:European Journal of Histochemistry Ejh

Extracto: When it is not possible to perform histological investigations on the face, to understand its characteristics and dynamics, ultrasound with a 24 MHz probe would seem to be the most suitable method, while elastosonography could be a valid method for evaluating the stiffness of the structural components.

Cita:Eur J Histochem 2024 Apr 12; 68 (2)

Autor/es:Veronese, Sheila (a)
Costa, Ezio (b)

institución:(a) Department of Neuroscience, Biomedicine, and Movement Sciences, University of Verona. sheila.veronese@univr.it.
(b) Ezio Costa Clinic, Sona (VR). ezio@dottoreziocosta.it.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Italia

Sitio web:http://dx.doi.org/10.4081/ejh.2024.3912

Reliability and measurement error of exercise-induced hypoalgesia in pain-free adults and adults with musculoskeletal pain

Fuente:Scandinavian Journal of Pain

Tipo de trabajo:Revisión sistemática

Extracto: We concluded, with a very low level of certainty, that the reliability and measurement error of EIH is, in pain-free adults, respectively, "insufficient" and "indeterminate." Future studies should focus on people with MSK pain and could consider using tailored exercises, other test modalities than pressure pain threshold, rater/assessor blinding, and strict control of the sources of variations (e.g., participants' expectations).

Claves:exercise, exercise-induced hypoalgesia, humans, pain modulation, psychometrics

Cita:Scand J Pain 2024 Jan 1; 24 (1)

Autor/es:Aron, Vladimir (a)
Strul, David (b)

institución:(a) Faculty of Medicine, Institute of Neuroscience (IoNS), Université Catholique de Louvain, Brussels B-1200, Belgium.
(b) Hôpitaux Iris-Sud, Bruxelles, Belgium.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Alemania

Sitio web:http://dx.doi.org/10.1515/sjpain-2023-0104

Very Long-Term Functional Outcomes and Dependency in Children With Anti-NMDA Receptor Encephalitis.

Fuente:Neurology(r) Neuroimmunology & Neuroinflammation

Extracto: The younger the patient at disease onset, the more probable it was to remain with multidomain deficits and dependent on sociofamiliar support.

Cita:Neurol Neuroimmunol Neuroinflamm 2024 May; 11 (3) : e200235.

Autor/es:Chen, Li-Wen (a)
Olivé-Cirera, Gemma (b)

institución:(a) From the Group of Experimental Neuroimmunology (L.-W.C., G.O.-C., E.G.F., T.A., J.D.), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS) and Caixa Research Institute, Barcelona, Spain; Department of Pediatrics (L.-W.C.), National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan; Pediatric Neurology Unit (G.O.-C.), Hospital Parc Taulí de Sabadell; Neurology Service (E.G.F., J.D.), Hospital Clínic Barcelona; Pediatric Neuroimmunology Unit (E.G.F., T.A.), Neurology Department, Sant Joan de Déu Children's Hospital, Barcelona, Spain; Division of Neurology (M.M.S.), Hospital das Clinicas (HCFMUSP), Faculdade de Medicina, University of São Paulo, Brazil; Department of Neurology (T.I.), Kitasato University School of Medicine, Sagamihara, Japan; Centro de Investigación Biomédica en Red (J.D.), Enfermedades Raras (CIBERER), Spain; Department of Neurology (J.D.), Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA; and University of Barcelona (J.D.), Barcelona, Spain.
(b) From the Group of Experimental Neuroimmunology (L.-W.C., G.O.-C., E.G.F., T.A., J.D.), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS) and Caixa Research Institute, Barcelona, Spain; Department of Pediatrics (L.-W.C.), National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan; Pediatric Neurology Unit (G.O.-C.), Hospital Parc Taulí de Sabadell; Neurology Service (E.G.F., J.D.), Hospital Clínic Barcelona; Pediatric Neuroimmunology Unit (E.G.F., T.A.), Neurology Department, Sant Joan de Déu Children's Hospital, Barcelona, Spain; Division of Neurology (M.M.S.), Hospital das Clinicas (HCFMUSP), Faculdade de Medicina, University of São Paulo, Brazil; Department of Neurology (T.I.), Kitasato University School of Medicine, Sagamihara, Japan; Centro de Investigación Biomédica en Red (J.D.), Enfermedades Raras (CIBERER), Spain; Department of Neurology (J.D.), Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA; and University of Barcelona (J.D.), Barcelona, Spain.

Formato:Informe impreso

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1212/NXI.0000000000200235

Multilocus pathogenic variants contribute to intrafamilial clinical heterogeneity: a retrospective study of sibling pairs with neurodevelopmental disorders.

Fuente:Bmc Medical Genomics

Extracto: This study sheds light on the significance of considering MPVs in families with affected sibling pairs and the role of ROH as an adjuvant tool in explaining clinical variability within families. Identifying individuals carrying MPVs may have implications for disease management, identification of possible disease risks to different family members, genetic counseling and exploring personalized treatment approaches.

Claves:Exome sequencing, Multilocus pathogenic variation, Neurodevelopmental disorders, Runs-of-homozygosity

Cita:BMC Med Genomics 2024 Apr 16; 17 (1) : 85.

Autor/es:Bozkurt-Yozgatli, Tugce (a)
Pehlivan, Davut (b)

institución:(a) Department of Biostatistics and Bioinformatics, Institute of Health Sciences, Acibadem Mehmet Ali Aydinlar University, Istanbul, Turkey.
(b) Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, University of Texas Health Science Center at Houston, Houston, TX, USA.

Conflicto:J.R.L. has stock ownership in 23andMe and is a paid consultant for Genomics International. The Department of Molecular and Human Genetics at Baylor College of Medicine derives revenue from molecular genetic and genomic testing offered at Baylor Genetics (BG) (http://www.bcm.edu/geneticlabs/). J.R.L. serves on the Scientific Advisory Board of BG. D.P. provides consulting service for Ionis Pharmaceuticals. The other authors declare... no competing financial interests.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12920-024-01852-4

Analysis of ischemic stroke-mediated effects on blood-brain barrier properties along the arteriovenous axis assessed by intravital two-photon imaging.

Fuente:Fluids and Barriers of The Cns

Extracto: Taken together, this in vivo two-photon imaging and analysis protocol will be useful in future studies investigating the molecular and cellular mechanisms, and the spatial contribution, of BBB breach to disease progression which might ultimately aid the development of new and more precise treatment strategies for ischemic stroke.

Claves:Arteriovenous axis, Blood–brain barrier breach, Intravital imaging, Ischemic stroke, Leakage, Longitudinal imaging, Two-photon microscopy, Vascular remodeling

Cita:Fluids Barriers CNS 2024 Apr 15; 21 (1) : 35.

Autor/es:Protzmann, Jil (a)
Jung, Felix (b)

institución:(a) Department of Medical Biochemistry and Biophysics, Division of Vascular Biology, Karolinska Institutet, Solnavägen 9, Stockholm, Sweden, 17165.
(b) Department of Neuroscience Karolinska Institutet, Solnavägen 9, Stockholm, Sweden, 17165.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12987-024-00537-5

Positive Emotional Responses to Socially Assistive Robots in People With Dementia: Pilot Study.

Fuente:Jmir Aging

Tipo de trabajo:Estudio aleatorizado y controlado

Extracto: By quantifying the emotional responses of people with dementia, this study highlighted that socially assistive robots may be more effective in eliciting positive emotions when multiple sensory stimuli, including tactile stimuli, are involved. More studies, including randomized controlled trials, are required to further explore the effectiveness of using socially assistive robots in dementia care.

Claves:dementia care, emotion, expression intensity, facial expression, gerontechnology, gerontology, long-term care, robotics, sensory modality

Cita:JMIR Aging 2024 Apr 11; 7 : e52443.

Autor/es:Otaka, Eri (a)
Osawa, Aiko (b)

institución:(a) Laboratory of Practical Technology in Community, Assistive Robot Center, National Center for Geriatrics and Gerontology Research Institute, Obu, Aichi, Japan.
(b) Department of Rehabilitation Medicine, National Center for Geriatrics and Gerontology, Obu, Aichi, Japan.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Canadá

Sitio web:http://dx.doi.org/10.2196/52443

Predictability of intelligence and age from structural connectomes.

Predictability of intelligence and age from structural connectomes.

Fuente:Plos One

Extracto: Our findings suggest a practical and scalable processing and analysis framework to explore broader research topics employing brain MR imaging.

Cita:PLoS One 2024; 19 (4) : e0301599.

Autor/es:Kopetzky, Sebastian J (a)
Li, Yong (b)

institución:(a) Labvantage-Biomax GmbH, Planegg, Germany.
(b) School of Life Sciences, Technical University of Munich, Freising, Germany.

Conflicto:SJK and YL were employed with Labvantage – Biomax GmbH and therefore will be affected by any commercial implications caused by this manuscript. This does not alter our adherence to PLOS ONE policies on sharing data and materials.

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1371/journal.pone.0301599

Audiovisual Moments in Time: A large-scale annotated dataset of audiovisual actions.

Fuente:Plos One

Extracto: We anticipate that the newly annotated AVMIT dataset will serve as a valuable resource for research and comparative experiments involving computational models and human participants, specifically when addressing research questions where audiovisual correspondence is of critical importance.

Cita:PLoS One 2024; 19 (4) : e0301098.

Autor/es:Joannou, Michael (a)
Rotshtein, Pia (b)

institución:(a) Computational Neuroscience and Cognitive Robotics Centre, University of Birmingham, Birmingham, United Kingdom.
(b) Computational Neuroscience and Cognitive Robotics Centre, University of Birmingham, Birmingham, United Kingdom.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1371/journal.pone.0301098

Relaxation Along a Fictitious Field, continuous wave T1rho, adiabatic T1rho and adiabatic T2rho imaging of human gliomas at 3T: A feasibility study.

Fuente:Plos One

Extracto: Future larger prospective clinical trials are warranted to evaluate these methods further.

Cita:PLoS One 2024; 19 (4) : e0296958.

Autor/es:Jambor, Ivan (a)
Steiner, Aida (b)

institución:(a) Department of Radiology, University of Turku, Turku, Finland.
(b) Enterprise Service Group-Radiology, Mass General Brigham, Boston, MA, United States of America.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1371/journal.pone.0296958

Effects of working from home on lifestyle behaviors and mental health during the COVID-19 pandemic: A survey study.

Fuente:Plos One

Extracto: These findings highlight health-related impact of WH during the COVID-19 pandemic that may inform future strategies and policies to improve employees' health and well-being.

Cita:PLoS One 2024; 19 (4) : e0300812.

Autor/es:Scoditti, Egeria (a)
Bodini, Antonella (b)

institución:(a) Institute of Clinical Physiology (IFC), National Research Council (CNR), Lecce, Italy.
(b) Institute for Applied Mathematics and Information Technologies "E. Magenes" (IMATI), National Research Council (CNR), Milano, Italy.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1371/journal.pone.0300812

Metacognitive evaluation of postdecisional perceptual representations.

Metacognitive evaluation of postdecisional perceptual representations.

Fuente:Journal of Vision

Extracto: These results can be explained by a model assuming confidence heavily relies on postdecisional internal representations of visual stimuli that degrade over time, where high-level representations are more persistent.

Cita:J Vis 2024 Apr 1; 24 (4) : 2.

Autor/es:Balsdon, Tarryn (a)
Wyart, Valentin (b)

institución:(a) Laboratoire des Systèmes Perceptifs (CNRS UMR 8248), DEC, ENS, PSL University, Paris, France.
(b) https://orcid.org/0000-0002-3122-6630.

Formato:Informe impreso

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1167/jov.24.4.2

Real-world experience of teriflunomide in relapsing multiple sclerosis: paramagnetic rim lesions may play a role.

Real-world experience of teriflunomide in relapsing multiple sclerosis: paramagnetic rim lesions may play a role.

Fuente:Frontiers in Immunology

Extracto: Teriflunomide is effective in reducing ARR in Chinese patients with RRMS. Patients with less PRL burden, less frequent relapses, and relatively older age are likely to benefit more from teriflunomide, indicating that PRL might be a valuable measurement to inform clinical treatment decision.

Claves:magnetic resonance imaging, multiple sclerosis, no evidence of disease activity, paramagnetic rim lesion, teriflunomide

Cita:Front Immunol 2024; 15 : 1343531.

Autor/es:Tan, Hongmei (a)
Li, Xiang (b)

institución:(a) Department of Neurology, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China.
(b) National Center for Neurological Disorders, Shanghai, China.

Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3389/fimmu.2024.1343531

Extracellular vesicles as carriers for noncoding RNA-based regulation of macrophage/microglia polarization: an emerging candidate regulator for lung and traumatic brain injuries.

Fuente:Frontiers in Immunology

Extracto: The conclusion of this review will emphasize the clinical opportunities presented by EV-ncRNAs, underscoring their potential functions as both biomarkers and targets for therapeutic interventions.

Claves:extracellular vesicles, lung brain injury, macrophage/microglia polarization, noncoding RNA, traumatic brain injury

Cita:Front Immunol 2024; 15 : 1343364.

Autor/es:Chen, Zhihong (a)
Zhang, Jingang (b)

institución:(a) Department of Respiratory Medicine, The Third People's Hospital of Longgang District, Shenzhen, China.
(b) Department of Orthopedic, The Third People's Hospital of Longgang District, Shenzhen, China.

Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3389/fimmu.2024.1343364