Study protocol: exercise training for treating major depressive disorder in multiple sclerosis.

Study protocol: exercise training for treating major depressive disorder in multiple sclerosis.

Fuente:Bmc Neurology

Extracto: The registration occurred before we initiated recruitment on June 2, 2023.

Claves:Behavior change, Depression, Exercise, Mental health, Mood, Multiple sclerosis, Neurological disease, Physical activity, Telehealth

Cita:BMC Neurol 2024 Apr 17; 24 (1) : 131.

Autor/es:Motl, Robert W (a)
Bombardier, Charles H (b)

institución:(a) Department of Kinesiology and Nutrition, University of Illinois at Chicago, Chicago, IL, 60612, USA. robmotl@uic.edu.
(b) Department of Rehabilitation Medicine, University of Washington, Seattle, WA, USA.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12883-024-03634-y

Potential of niacin skin flush response in adolescent depression identification and severity assessment: a case-control study.

Potential of niacin skin flush response in adolescent depression identification and severity assessment: a case-control study.

Fuente:Bmc Psychiatry

Extracto: The NSFR demonstrates potential as an objective biomarker for adolescent Depressive Disorder, aiding in screening, assessing severity, and enhancing insights into its pathophysiology and diagnostic precision.

Claves:Adolescent depressive disorder, Behavioral and emotional disorders typically emerging in childhood and adolescence, Biomarker, Niacin skin flush response, Precision diagnosis

Cita:BMC Psychiatry 2024 Apr 17; 24 (1) : 290.

Autor/es:Feng, Jie (a)
Min, Wenjiao (b)

institución:(a) Department of Psychosomatics, School of Medicine, Sichuan Provincial Center for Mental Health, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, No. 32, West second Section, 1st Ring Road, 610041, Chengdu, Sichuan, China.
(b) Key Laboratory of Psychosomatic Medicine, Chinese Academy of Medical Sciences, Chengdu, China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12888-024-05728-w

Development of mental health first-aid guidelines for a person after a potentially traumatic event

Fuente:Bmc Psychiatry

Tipo de trabajo:Consenso

Extracto: The study showed a high level of acceptance of the original actions suggested for inclusion in the guidelines for Australia, but also a significant number of new statements that highlight the importance of the adaptation process. Further research on the dissemination of these guidelines into a Mental Health First Aid training course for Chile and Argentina is still required.

Claves:Argentina, Chile, Cultural adaptation, Delphi study, Mental health first aid (MHFA), Trauma

Cita:BMC Psychiatry 2024 Apr 17; 24 (1) : 291.

Autor/es:Agrest, Martín (a)
Tapia-Muñoz, Thamara (b)

institución:(a) Proyecto Suma. Güemes 4130 (1425), Ciudad Autónoma de Buenos Aires, Buenos Aires, Argentina. magrest66@gmail.com.
(b) Facultad de Psicología, Instituto de Investigaciones, Universidad de Buenos Aires, Buenos Aires, Argentina. magrest66@gmail.com.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12888-024-05631-4

IgM anti-GM2 antibodies in patients with multifocal motor neuropathy target Schwann cells and are associated with early onset.

IgM anti-GM2 antibodies in patients with multifocal motor neuropathy target Schwann cells and are associated with early onset.

Fuente:Journal of Neuroinflammation

Extracto: Circulating IgM anti-GM2 antibodies define a subgroup of patients with MMN that has an earlier onset of disease. These antibodies probably target SCs specifically and activate complement, similarly as IgM anti-GM1 on MNs. Our data indicate that complement activation by IgM antibodies bound to SCs and MNs underlies MMN pathology.

Claves:Anti-ganglioside antibodies, Complement, IgM anti-GM2, Multifocal motor neuropathy, Schwann cells

Cita:J Neuroinflammation 2024 Apr 17; 21 (1) : 100.

Autor/es:Budding, Kevin (a)
Bos, Jeroen W (b)

institución:(a) Center for Translational Immunology, University Medical Center Utrecht, Utrecht, The Netherlands.
(b) Department of Neurology and Neurosurgery, University Medical Center Utrecht Brain Center, Utrecht, The Netherlands.

Conflicto:KB, EdZ, KD, LMB are employees of the UMC Utrecht on a research service collaboration with argenx BVBA. JWB reports no disclosures. EMZ reports no disclosures. EJNG reports a research grants from the Prinses Beatrix Spierfonds and has received teaching fees from Biogen, all paid to the institution. BCJ reports grants for research from the GBS/CIDP Foundation International, Prinses Beatrix... Spierfonds, Horizon 2020, NIH, Erasmus MC, Annexon, CSL-Behring, Grifols, Hansa Biopharma, Roche and Octapharma. BCJ is chairing the Steering Committee of the International GBS Outcome Study (IGOS), a member of the Advisory Board of Hansa Biopharma and Annexon and of the Global Medical Advisory Board of the GBS-CIDP Foundation International. RH reports grants from the GBS/CIDP Foundation International, NIH and the T2B collaboration project funded by PPP Allowance made available by Top Sector Life Sciences & Health to Samenwerkende Gezondheidsfondsen (SGF) under project number LSHM18055-SGF to stimulate public-private partnerships and co-financing by health foundations that are part of the SGF. HSG has received research grants from the Prinses Beatrix Spierfonds, speaker fees, and consultancy for Takeda and Quaralis all paid to the institution. EC reports no disclosures. JHWL reports no disclosures. LHvdB received an educational grant from Takeda; serves on the editorial boards of Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration; and receives research support from the Netherlands ALS Foundation. CEH provides consultancy services to argenx BVBA. WLvdP serves on the scientific advisory board for SAB SMA Europe; provides ad hoc consultancy for argenx BVBA, Biogen, and Novartis genetherapies; is the local PI for the ARDA and ARDA + trials and receives research support from the Prinses Beatrix Spierfonds, Vriendenloterij and Stichting Spieren voor Spieren.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12974-024-03090-y

Effectiveness of interventions to improve adherence to antidepressant medication in patients with depressive disorders: a cluster randomized controlled trial.

Effectiveness of interventions to improve adherence to antidepressant medication in patients with depressive disorders: a cluster randomized controlled trial.

Fuente:Frontiers in Public Health

Tipo de trabajo:Estudio aleatorizado y controlado

Extracto: The assessed interventions to improve adherence in patients with depressive disorder were effective for depression symptoms and mental quality of life, even over the long term. However, no effect on antidepressant adherence was observed.

Claves:Spain, antidepressive agents, depression, randomized controlled trial, treatment adherence and compliance

Cita:Front Public Health 2024; 12 : 1320159.

Autor/es:Del Pino-Sedeño, Tasmania (a)
González-Pacheco, Himar (b)

institución:(a) Canary Islands Health Research Institute Foundation (FIISC), Tenerife, Spain.
(b) Evaluation Unit (SESCS), Canary Islands Health Service (SCS), Tenerife, Spain.

Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3389/fpubh.2024.1320159

Case report: EBV-related eye orbits and sinuses lymphohistiocytic infiltration responsive to rituximab in a patient with X lymphoproliferative syndrome type 1.

Case report: EBV-related eye orbits and sinuses lymphohistiocytic infiltration responsive to rituximab in a patient with X lymphoproliferative syndrome type 1.

Fuente:Frontiers in Immunology

Extracto: We described an unusual presentation of incomplete HLH in a patient affected with XLP1: an EBV-driven infiltration of the orbits and paranasal sinuses. This led us to a challenging differential diagnosis of lymphoma-associated hemophagocytic syndrome, which can be frequently observed in patients with XLP1. Considering the extremely poor prognosis of this clinical finding, we sought for a prompt diagnosis and managed to obtain it and to immediately establish the right treatment on the basis of the pathological finding.

Claves:EBV, SH2D1A, X lymphoproliferative syndrome type 1, eye lymphohistiocytic infiltration, rituximab

Cita:Front Immunol 2024; 15 : 1370991.

Autor/es:Giardino, Giuliana (a)
Lanni, Vittoria (b)

institución:(a) Department of Translational Medical Sciences, Pediatric Section, Federico II University of Naples, Naples, Italy.
(b) Department of Neurosciences, Reproductive Sciences and Dentistry, University of Naples Federico II, Naples, Italy.

Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3389/fimmu.2024.1370991

Overcoming Methodological Challenges for Advancing Stem Cell Therapies in Parkinson's Disease.

Overcoming Methodological Challenges for Advancing Stem Cell Therapies in Parkinson's Disease.

Fuente:Cell Transplantation

Extracto: Overall, this review underscores the need for further research and innovation to overcome the hurdles in realizing the potential of stem cell-based therapies for PD.

Claves:Parkinson’s disease, methodological challenges, sham surgery, stem cell therapy, treatment algorithm

Cita:Cell Transplant 2024 Jan-Dec; 33 : 9636897241246355.

Autor/es:Polgar, Stephen (a)
Finkelstein, David I (b)

institución:(a) School of Health and Biomedical Sciences, RMIT University, Melbourne, VIC, Australia.
(b) University of Melbourne, Florey Institute of Neuroscience and Mental Health, Parkville, VIC, Australia.

Conflicto:Declaration of Conflicting InterestsThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

Formato:Informe impreso

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1177/09636897241246355

White Matter Alterations in Military Service Members With Remote Mild Traumatic Brain Injury.

White Matter Alterations in Military Service Members With Remote Mild Traumatic Brain Injury.

Fuente:Jama Network Open

Extracto: AND RELEVANCE: In this case-control study of military-related mTBI, the results suggest that advanced magnetic resonance imaging techniques using NODDI can reveal white matter microstructural alterations associated with neuropsychiatric symptoms in the chronic phase of mTBI. Diffusion trends observed throughout widespread white matter regions-of-interest may reflect mechanisms of neurodegeneration as well as postinjury tissue scarring and reorganization.

Cita:JAMA Netw Open 2024 Apr 1; 7 (4) : e248121.

Autor/es:Kim, Sharon (a)
Ollinger, John (b)

institución:(a) Program in Neuroscience, Uniformed Services University of Health Sciences, Bethesda, Maryland.
(b) School of Medicine, Uniformed Services University of Health Sciences, Bethesda, Maryland.

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1001/jamanetworkopen.2024.8121

Reading of ingroup politicians' smiles triggers smiling in the corner of one's eyes.

Reading of ingroup politicians' smiles triggers smiling in the corner of one's eyes.

Fuente:Plos One

Extracto: Implications for verbal communication in the political context are discussed.

Cita:PLoS One 2024; 19 (4) : e0290590.

Autor/es:Fino, Edita (a)
Menegatti, Michela (b)

institución:(a) Department of Psychology "Renzo Canestrari", Alma Mater Studiorum Università di Bologna, Bologna, Italy.
(b) Department of Psychology "Renzo Canestrari", Alma Mater Studiorum Università di Bologna, Bologna, Italy.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1371/journal.pone.0290590

"Could a subset of joint mobility tests define generalized joint hypermobility?": A descriptive observational inception study.

Fuente:Plos One

Tipo de trabajo:Consenso

Extracto: It is probably not possible to choose a subset of joint mobility tests to define GJH. In order not to overlook generalized joint hypermobility, a broader assessment of different joint types and sizes of joints appears to be needed. The prevalence of generalized joint hypermobility is dependent on joint hypermobility limit and the chosen combination of joint mobility tests.

Cita:PLoS One 2024; 19 (4) : e0298649.

Autor/es:Schlager, Angela (a)
Nilsson-Wikmar, Lena (b)

institución:(a) Department of Public Health and Caring Sciences, Uppsala University, Uppsala, Sweden.
(b) Department of Neurobiology, Care Sciences and Society, Division of Physiotherapy, Karolinska Institutet, Huddinge, Sweden.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1371/journal.pone.0298649

Risk factors of reattempt among suicide attempters in South Korea

Fuente:Plos One

Tipo de trabajo:Estudio de cohortes

Extracto: Various risk factors including demographics, clinical characteristics, and medications should be considered to prevent suicide reattempts among suicide attempters, and patients with depressive disorder should be monitored more closely.

Cita:PLoS One 2024; 19 (4) : e0300054.

Autor/es:Kim, Min Ji (a)
Yang, Jeong Hun (b)

institución:(a) Department of Psychiatry, Seoul National University College of Medicine, Seoul, Korea.
(b) Department of Neuropsychiatry, Seoul National University Hospital, Seoul, Korea.

Conflicto:I have read the journal’s policy and the authors of this manuscript have the following competing interests: MJ Koh, Y Kim, and B Lee are employees of Janssen Korea Ltd. YM Ahn declared a research fund from Janssen Korea Ltd. and participated in speakers’ events in Janssen Korea Ltd, Lundbeck Korea Co., Ltd., and Korea Otsuka Pharmaceutical. The remaining authors... hors have nothing to disclose.

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1371/journal.pone.0300054

The effect of behavioral therapy on dysphagia of acute ischemic stroke patients feeding with a nasogastric tube.

Fuente:Plos One

Extracto: This study highlights the potential of behavioral therapy as an effective intervention for dysphagia rehabilitation in stroke patients.

Cita:PLoS One 2024; 19 (4) : e0299068.

Autor/es:Hien, Nguyen Thi Thu (a)
Thong, Tran Huu (b)

institución:(a) Dermatology Department, Bach Mai Hospital, Hanoi, Vietnam.
(b) Department of Nursing, Bach Mai Hospital, Hanoi, Vietnam.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1371/journal.pone.0299068

Role and knowledge of nurses in the management of non-communicable diseases in Africa

Fuente:Plos One

Tipo de trabajo:Revisión

Extracto: There is significant potential for nurses to enhance the screening, diagnosis, and treatment of chronic diseases in Africa. Achieving this requires a combination of rigorous training and effective supervision, supported by robust policies. To address varying levels of knowledge, tailored training programs should be devised. Further research is warranted to establish the effectiveness of nurse-led interventions on population health outcomes.

Cita:PLoS One 2024; 19 (4) : e0297165.

Autor/es:Toniolo, Jean (a)
Ngoungou, Edgard Brice (b)

institución:(a) Inserm U1094, IRD UMR270, Univ. Limoges, CHU Limoges, EpiMaCT - Epidemiology of Chronic Diseases in Tropical Zone, Institute of Epidemiology and Tropical Neurology, OmegaHealth, Limoges, France.
(b) Département d'Epidémiologie Biostatistiques et Informatique Médicale (DEBIM)/ Unité de Recherche en Epidémiologie des Maladies Chroniques et Santé Environnement (UREMCSE), Faculté de Médecine, Université des Sciences de la Santé, Owendo, Gabon.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1371/journal.pone.0297165

How long is long? Word length effects in reading correspond to minimal graphemic units: An MEG study in Bangla.

Fuente:Plos One

Extracto: Our findings suggest that minimal graphemic units could serve as a suitable metric for measuring word length in non-alphabetic orthographies such as Bangla.

Cita:PLoS One 2024; 19 (4) : e0292979.

Autor/es:Moitra, Swarnendu (a)
Chacón, Dustin A (b)

institución:(a) Department of Linguistics, Queen Mary University of London, London, United Kingdom.
(b) Department of Linguistics, University of Georgia, Athens, Georgia, United States of America.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1371/journal.pone.0292979

Perceptual (but not acoustic) features predict singing voice preferences.

Perceptual (but not acoustic) features predict singing voice preferences.

Fuente:Scientific Reports

Extracto: Our results indicate that singing voice preferences are not grounded in acoustic attributes of the voices per se, but in how these features are perceptually interpreted by listeners.

Cita:Sci Rep 2024 Apr 18; 14 (1) : 8977.

Autor/es:Bruder, Camila (a)
Poeppel, David (b)

institución:(a) Max Planck Institute for Empirical Aesthetics, Frankfurt am Main, Germany. camila.bruder@ae.mpg.de.
(b) New York University, New York, NY, USA.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1038/s41598-024-58924-9

Longitudinal microstructural changes in 18 amygdala nuclei resonate with cortical circuits and phenomics.

Longitudinal microstructural changes in 18 amygdala nuclei resonate with cortical circuits and phenomics.

Fuente:Communications Biology

Extracto: The obtained structural plasticity findings motivate hypotheses about the specific functions of distinct amygdala nuclei in humans.

Cita:Commun Biol 2024 Apr 18; 7 (1) : 477.

Autor/es:Ghanem, Karam (a)
Saltoun, Karin (b)

institución:(a) The Neuro - Montreal Neurological Institute (MNI), McConnell Brain Imaging Centre, Department of Biomedical Engineering, Faculty of Medicine, School of Computer Science, McGill University, Montreal, Canada. ghanemkaram12@gmail.com.
(b) Mila - Quebec Artificial Intelligence Institute, Montreal, QC, Canada. ghanemkaram12@gmail.com.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1038/s42003-024-06187-5

Joint transformer architecture in brain 3D MRI classification: its application in Alzheimer's disease classification.

Joint transformer architecture in brain 3D MRI classification: its application in Alzheimer's disease classification.

Fuente:Scientific Reports

Extracto: Our proposed method offers researchers an approach to more efficient early clinical diagnosis and interventions.

Claves:Alzheimer’s disease, MRI, Sequence classification, Transfer learning, Vision transformer

Cita:Sci Rep 2024 Apr 18; 14 (1) : 8996.

Autor/es:Alp, Sait (a)
Akan, Taymaz (b)

institución:(a) Department of Computer Engineering, Erzurum Technical University, Erzurum, Turkey.
(b) Division of Clinical Informatics, Department of Medicine, Louisiana State University Health Sciences Center - Shreveport, Shreveport, LA, 71103-4228, USA.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1038/s41598-024-59578-3

Whole-cycle management of women with epilepsy of child-bearing age: ontology construction and application.

Whole-cycle management of women with epilepsy of child-bearing age: ontology construction and application.

Fuente:Bmc Medical Informatics and Decision Making

Tipo de trabajo:Consenso

Extracto: Our ontology and the associated online question and answer system hold the potential to serve as a scalable assistant for healthcare providers engaged in the management of women with epilepsy (WWE). In the future, this developmental framework has the potential for broader application in the context of long-term management of more intricate chronic health conditions.

Claves:Epilepsy, Online question-and-answer system, Ontology, Women health

Cita:BMC Med Inform Decis Mak 2024 Apr 18; 24 (1) : 101.

Autor/es:Xia, Yilin (a)
Duan, Yifei (b)

institución:(a) Department of Neurology, West China Hospital, Sichuan University, #37 Guoxue Alley, Wuhou District, 610041, Chengdu, Sichuan Province, China.
(b) Department of Neurology, West China Hospital, Sichuan University, #37 Guoxue Alley, Wuhou District, 610041, Chengdu, Sichuan Province, China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12911-024-02509-z

Homecare workers - an untapped resource in preventing emergency department visits among older individuals? A qualitative interview study from Sweden.

Homecare workers - an untapped resource in preventing emergency department visits among older individuals? A qualitative interview study from Sweden.

Fuente:Bmc Geriatrics

Extracto: HCWs feel that they have an important role in the health management of older individuals living at home. Still, they feel as an untapped resource in the prevention of ED visits. They deem that improved coordination and communication between primary care, ED, and homecare organisations as well as proactive care would enable them to add significantly to the prevention of ED visits.

Claves:Emergency departments, Frail older adults, Homecare aids, Primary care, Qualitative research

Cita:BMC Geriatr 2024 Apr 18; 24 (1) : 350.

Autor/es:Bastholm-Rahmner, Pia (a)
Bergqvist, Monica (b)

institución:(a) Academic Primary Healthcare Center, Region Stockholm, Sweden. pia.bastholm.rahmner@ki.se.
(b) Department of Laboratory Medicine, Division of Clinical Pharmacology, Karolinska Institutet, Karolinska Institutet, Stockholm, Sweden. pia.bastholm.rahmner@ki.se.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12877-024-04906-5

Integrating training in evidence-based medicine and shared decision-making: a qualitative study of junior doctors and consultants.

Integrating training in evidence-based medicine and shared decision-making: a qualitative study of junior doctors and consultants.

Fuente:Bmc Medical Education

Extracto: These findings suggested that future medical education and research should include training that integrates EBM and SDM that acknowledges the complex environment in which this training must be put into practice, and considers strategies to overcome barriers to the implementation of EBM-SDM learning in practice.

Claves:Evidence-based medicine, Medical education, Medical practice, Person-centered care, Shared decision-making

Cita:BMC Med Educ 2024 Apr 18; 24 (1) : 418.

Autor/es:Simons, Mary (a)
Fisher, Georgia (b)

institución:(a) Centre for Healthcare Resilience and Implementation Science, Australian Institute of Health Innovation, Macquarie University, Sydney, NSW, 2109, Australia. mary.simons@mq.edu.au.
(b) Australian Institute of Health Innovation, 75 Talavera Rd, Macquarie Park, NSW, 2109, Australia. mary.simons@mq.edu.au.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12909-024-05409-y