SOFA score performs worse than age for predicting mortality in patients with COVID-19.

SOFA score performs worse than age for predicting mortality in patients with COVID-19.

Fuente:Plos One

Extracto: Our findings bring into question the utility of SOFA score-based resource allocation in COVID-19 crisis standards of care.

Cita:PLoS One 2024; 19 (5) : e0301013.

Autor/es:Sherak, Raphael A G (a)
Sajjadi, Hoomaan (b)

institución:(a) Yale Department of Emergency Medicine, Yale School of Medicine, New Haven, CT, United States of America.
(b) Department of Computer Science and Engineering, Center for Remote Health Technologies and Systems, Texas A&M Univ, College Station, TX, United States of America.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1371/journal.pone.0301013

Machine learning-based model to predict delirium in patients with advanced cancer treated with palliative care: a multicenter, patient-based registry cohort.

Machine learning-based model to predict delirium in patients with advanced cancer treated with palliative care: a multicenter, patient-based registry cohort.

Fuente:Scientific Reports

Extracto: We believe that this model will assist healthcare providers in treating patients with delirium and advanced cancer.

Claves:Cancer, Delirium, Feature importance, Machine learning, Palliative care

Cita:Sci Rep 2024 May 20; 14 (1) : 11503.

Autor/es:Kim, Yu Jung (a)
Lee, Hayeon (b)

institución:(a) Division of Hematology and Medical Oncology, Department of Internal Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, South Korea.
(b) Department of Biomedical Engineering, Kyung Hee University, 1732 Deogyeong-daero, Giheung-gu, Yongin, 17104, South Korea.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1038/s41598-024-61627-w

Prevalence of HIV-related stigma manifestations and their contributing factors among people living with HIV in Sweden - a nationwide study.

Prevalence of HIV-related stigma manifestations and their contributing factors among people living with HIV in Sweden - a nationwide study.

Fuente:Bmc Public Health

Extracto: The most dominating stigma feature was anticipation of stigma. Female gender, shorter time since HIV diagnosis, feelings of hopelessness, non-sharing HIV status, and lack of available emotional HIV-related support constituted potential vulnerability factors of the four HIV-related stigma manifestations. Our findings highlight the vital necessity to support people living with HIV to increase their resilience to stigma in its different forms. Exploring associated factors of HIV-related stigma manifestations may give an indication of what circumstances may increase the risk of stigma burden and factors amenable to targeted interventions. As individual stigma-reductions interventions cannot be performed isolated from HIV-related stigma and discrimination in society, a key challenge is to intensify anti-stigma interventions also on the societal level.

Claves:HIV, People living with HIV, Stigma, Sweden

Cita:BMC Public Health 2024 May 20; 24 (1) : 1360.

Autor/es:Nilsson Schönnesson, Lena (a)
Dahlberg, Marie (b)

institución:(a) Department of Global Public Health, Karolinska Institutet, Stockholm, Sweden. lena.nilsson.schonnesson@ki.se.
(b) Department of Learning, Informatics, Management and Ethics, Karolinska Institutet, Stockholm, Sweden.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12889-024-18852-9

Phenotypic and genetic analysis of children with unexplained neurodevelopmental delay and neurodevelopmental comorbidities in a Chinese cohort using trio-based whole-exome sequencing.

Phenotypic and genetic analysis of children with unexplained neurodevelopmental delay and neurodevelopmental comorbidities in a Chinese cohort using trio-based whole-exome sequencing.

Fuente:Orphanet Journal of Rare Diseases

Tipo de trabajo:Revisión

Extracto: Trio-WES testing is recommended for patients with unexplained NDD-NDCs that have severe-profound NDD or multiple NDCs, particularly those with accompanying ASD and head circumference abnormality, as these independent factors may increase the likelihood of genetic diagnosis using trio-WES. Moreover, NDD patients with pathogenic variants in CUL4B, KCNH1 and PLA2G6 should be aware of potential risks of developing ASD during their disease courses.

Claves:Autism spectrum disorder, Autism spectrum disorder-risk genes, Diagnostic yield, Head circumference abnormality, Neurodevelopmental comorbidities, Neurodevelopmental delay, Trio-based whole-exome sequencing

Cita:Orphanet J Rare Dis 2024 May 19; 19 (1) : 205.

Autor/es:Wu, Ruohao (a)
Li, Xiaojuan (b)

institución:(a) Department of Children's Neuro-endocrinology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, 510120, Guangdong, China.
(b) Children's Medical Center, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou Guangdong, 510120, China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s13023-024-03214-w

Causal effect of blood osteocalcin on the risk of Alzheimer's disease and the mediating role of energy metabolism.

Causal effect of blood osteocalcin on the risk of Alzheimer's disease and the mediating role of energy metabolism.

Fuente:Translational Psychiatry

Extracto: Further studies are warranted to elucidate the underlying physio-pathological mechanisms.

Cita:Transl Psychiatry 2024 May 20; 14 (1) : 205.

Autor/es:Guo, Xingzhi (a)
Yang, Yu-Ying (b)

institución:(a) Department of Geriatric Neurology, Shaanxi Provincial People's Hospital, Xi'an, 710068, Shaanxi, China.
(b) Xi'an Key Laboratory of Stem Cell and Regenerative Medicine, Institute of Medical Research, Northwestern Polytechnical University, Xi'an, 710072, Shaanxi, China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1038/s41398-024-02924-w

Untangling the relationship between smoking and systemic sclerosis: an analysis of the EUSTAR cohort.

Untangling the relationship between smoking and systemic sclerosis: an analysis of the EUSTAR cohort.

Fuente:Rmd Open

Extracto: Our stratified analysis demonstrates that smoking is associated with an increased risk for mortality in male SSc patients but not in women. Strikingly, smoking is associated with lower prevalence of ATA positivity, in particular in women. In both ATA-positive and ACA-positive patients, smoking is a risk factor for mortality, skin progression and 'any organ progression'.

Claves:Autoantibodies, Risk Factors, Smoking, Systemic Sclerosis

Cita:RMD Open 2024 May 20; 10 (2)

Autor/es:Ciaffi, Jacopo (a)
Liem, Sophie I E (b)

institución:(a) Medicine and Rheumatology Unit, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy jacopo.ciaffi@ior.it.
(b) Department of Biomedical and Neuromotor Sciences (DIBINEM), Alma Mater Studiorum University of Bologna, Bologna, Italy.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1136/rmdopen-2024-004101

Association of OPRM1 rs1799971, HTR1B rs6296 and COMT rs4680 polymorphisms with clinical phenotype among women with fibromyalgia.

Association of OPRM1 rs1799971, HTR1B rs6296 and COMT rs4680 polymorphisms with clinical phenotype among women with fibromyalgia.

Fuente:Scientific Reports

Extracto: Potential gene-to-gene interaction and their association with clinical phenotype in women with FMS should be further investigated in future studies including large sample sizes.

Claves:Fibromyalgia, Pain genes, Single nucleotide polymorphism

Cita:Sci Rep 2024 May 17; 14 (1) : 11273.

Autor/es:Fernández-de-Las-Peñas, César (a)
Ambite-Quesada, Silvia (b)

institución:(a) Department of Physical Therapy, Occupational Therapy, Physical Medicine and Rehabilitation, Universidad Rey Juan Carlos, Av. de Atenas S/N, 28922, Alcorcón, Madrid, Spain. cesar.fernandez@urjc.es.
(b) Center for Neuroplasticity and Pain (CNAP), Department of Health Science and Technology, Faculty of Medicine, SMI, Aalborg University, Aalborg, Denmark. cesar.fernandez@urjc.es.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1038/s41598-024-62240-7

Appendicular lean mass and the risk of stroke and Alzheimer's disease: a mendelian randomization study.

Appendicular lean mass and the risk of stroke and Alzheimer's disease: a mendelian randomization study.

Fuente:Bmc Geriatrics

Extracto: The two-sample MR analysis indicated that genetically predicted ALM was negatively related to AIS and AD. And the subgroup analysis of AIS revealed a negative causal effect of genetically predicted ALM on LAS or SVS. Future studies are required to further investigate the underlying mechanisms.

Claves:Alzheimer’s disease, Appendicular lean mass, Mendelian randomization, Sarcopenia, Stroke

Cita:BMC Geriatr 2024 May 18; 24 (1) : 438.

Autor/es:Zhu, Yueli (a)
Zhu, Feng (b)

institución:(a) Department of Geriatrics, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
(b) Key Laboratory of Diagnosis and Treatment of Aging and Physic-chemical Injury Diseases of Zhejiang Province, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12877-024-05039-5

Network-targeted transcranial direct current stimulation of the hypothalamus appetite-control network: a feasibility study.

Network-targeted transcranial direct current stimulation of the hypothalamus appetite-control network: a feasibility study.

Fuente:Scientific Reports

Extracto: Further studies need to evaluate the effects on eating behavior and metabolism.

Cita:Sci Rep 2024 May 18; 14 (1) : 11341.

Autor/es:Ester-Nacke, Theresa (a)
Berti, Katharina (b)

institución:(a) Institute for Diabetes Research and Metabolic Diseases (IDM) of the Helmholtz Center Munich at the University of Tübingen, Tübingen, Germany. Theresa.ester@med.uni-tuebingen.de.
(b) Department of Internal Medicine, Division of Endocrinology, Diabetology and Nephrology, Eberhard Karls University Tübingen, Tübingen, Germany. Theresa.ester@med.uni-tuebingen.de.

Conflicto:GR is a co-founder and shareholder and works for Neuroelectrics, a company developing medical devices for NIBS. RS works for Neuroelectrics. Outside of the current work, MH reports research grants from Boehringer Ingelheim and Sanofi to the University Hospital of Tübingen, participation in advisory board for Boehringer Ingelheim, Sanofi and Amryt, and lecture fees from Amryt, Bayer, Sanofi, Eli Lilly,... , Novartis, Novo Nordisk and Boehringer Ingelheim. TEN, KB, RV, CD, ALB, CP, HP and SK report no conflict of interest.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1038/s41598-024-61852-3

Reliability and validity of the modified shuttle test-paeds to measure cardiorespiratory fitness in children.

Reliability and validity of the modified shuttle test-paeds to measure cardiorespiratory fitness in children.

Fuente:Bmc Pediatrics

Extracto: Paeds appears to be a reliable and valid tool for estimating cardiorespiratory fitness in typically developing children aged 6-12 years and has the advantages of being shorter, needing less space, not requiring pacing and being self-motivational. More studies are needed to assess whether children reach an aerobic steady state in three minutes and how much of the results of the Paeds test can be explained by the agility component of the task (turning and grasping or aiming a bean bag). For clinical use, psychometric properties should be studied in various patient groups (e.g., ADHD, DCD, and children with intellectual disabilities).

Claves:Cardiorespiratory fitness, Modified shuttle test-paeds, Psychometric properties

Cita:BMC Pediatr 2024 May 17; 24 (1) : 343.

Autor/es:Aertssen, Wfm (a)
van de Kamp, A (b)

institución:(a) University for Professionals, Breda, The Netherlands. wendyaertssen@hotmail.com.
(b) University for Professionals, Breda, The Netherlands.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12887-024-04812-0

Cardiac Biomarker Change at 1 Year After Tafamidis Treatment and Clinical Outcomes in Patients With Transthyretin Amyloid Cardiomyopathy.

Cardiac Biomarker Change at 1 Year After Tafamidis Treatment and Clinical Outcomes in Patients With Transthyretin Amyloid Cardiomyopathy.

Fuente:Journal of The American Heart Association

Extracto: Deterioration in cardiac biomarkers during the first year after tafamidis treatment predicted a worse prognosis, suggesting the utility of serial assessment of cardiac biomarkers for monitoring the therapeutic response to tafamidis in patients with wild-type transthyretin amyloid cardiomyopathy.

Claves:B‐type natriuretic peptide, high‐sensitivity cardiac troponin T, tafamidis, wild‐type transthyretin amyloid cardiomyopathy

Cita:J Am Heart Assoc 2024 May 21; 13 (10) : e034518.

Autor/es:Kuyama, Naoto (a)
Takashio, Seiji (b)

institución:(a) Department of Cardiovascular Medicine, Graduate School of Medical Sciences Kumamoto University Kumamoto Japan.
(b) Department of Cardiovascular Medicine, Graduate School of Medical Sciences Kumamoto University Kumamoto Japan.

Formato:Informe impreso

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1161/JAHA.124.034518

Dynamic Mechanism of Cerebral Venous Disruption: Longitudinal Evidence From a Community-Based Cohort.

Fuente:Journal of The American Heart Association

Tipo de trabajo:Estudio de cohortes

Extracto: Our findings posed the dynamic pattern of brain parenchymal lesions related to DMVs injury, shedding light on the interactions and chronological roles of various pathological mechanisms.

Claves:brain atrophy, deep medullary veins, longitudinal study, neurodegenerative disease, white matter microstructure

Cita:J Am Heart Assoc 2024 May 21; 13 (10) : e034145.

Autor/es:Liu, Zi-Yue (a)
Wang, Pei (b)

institución:(a) Department of Neurology, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital Chinese Academy of Medical Sciences and Peking Union Medical College Beijing China.
(b) Department of Neurology, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital Chinese Academy of Medical Sciences and Peking Union Medical College Beijing China.

Formato:Informe impreso

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1161/JAHA.123.034145

ZOom Delivered Intervention Against Cognitive decline (ZODIAC) COVID-19 pandemic adaptations to the Post-Ischaemic Stroke Cardiovascular Exercise Study (PISCES)

ZOom Delivered Intervention Against Cognitive decline (ZODIAC) COVID-19 pandemic adaptations to the Post-Ischaemic Stroke Cardiovascular Exercise Study (PISCES)

Fuente:Trials

Tipo de trabajo:Estudio aleatorizado y controlado

Extracto: TRIAL REGISTRATION: Prospectively ACTRN12616000942459. Registered on July 2016.

Claves:Brain volume, Cognition, Dementia, Exercise training, Ischaemic stroke, Physical activity, Telerehabilitation

Cita:Trials 2024 May 18; 25 (1) : 329.

Autor/es:Brodtmann, Amy (a)
Billett, Alex (b)

institución:(a) Department of Neuroscience, School of Translational Medicine, Monash University, Melbourne, VIC, Australia. amy.brodtmann@monash.edu.
(b) The Florey, Melbourne, VIC, Australia. amy.brodtmann@monash.edu.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s13063-024-08154-1

Homozygous EPRS1 missense variant causing hypomyelinating leukodystrophy-15 alters variant-distal mRNA m(6)A site accessibility.

Homozygous EPRS1 missense variant causing hypomyelinating leukodystrophy-15 alters variant-distal mRNA m(6)A site accessibility.

Fuente:Nature Communications

Extracto: These results reveal a new RNA-dependent etiologic mechanism by which SNVs can influence gene expression and disease, consequently generating opportunities for personalized, RNA-based therapeutics targeting these disorders.

Cita:Nat Commun 2024 May 20; 15 (1) : 4284.

Autor/es:Khan, Debjit (a)
Ramachandiran, Iyappan (b)

institución:(a) Department of Cardiovascular and Metabolic Sciences, Cleveland Clinic, Lerner Research Institute, Cleveland, OH, USA.
(b) Department of Cardiovascular and Metabolic Sciences, Cleveland Clinic, Lerner Research Institute, Cleveland, OH, USA.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1038/s41467-024-48549-x

Genetic associations between Rapid Eye Movement (REM) sleep behavior disorder and cardiovascular diseases.

Genetic associations between Rapid Eye Movement (REM) sleep behavior disorder and cardiovascular diseases.

Fuente:Plos One

Extracto: Our study highlighted the potential associations between RBD and cardiovascular diseases at genetic level, including HF and MI. More studies were required to clarify the biological mechanisms involved the associations.

Cita:PLoS One 2024; 19 (5) : e0301112.

Autor/es:Xu, Pengfei (a)
Wei, Yitong (b)

institución:(a) Department of Neurosurgery, Nanyang Central Hospital, Nanyang, Henan, China.
(b) Department of Neurosurgery, Nanyang Central Hospital, Nanyang, Henan, China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1371/journal.pone.0301112

Deregulated miR-146a-3p alleviates disease progression in atherosclerosis through inactivating NF-?B: An experimental study.

Fuente:Medicine

Extracto: miR-146a-3p might inhibit inflammation by targeting NF-κB in AS progression, and miR-146a-3p/ NF-κB might provide novel biomarkers and therapeutic targets for the prevention of AS and related vascular events.

Cita:Medicine (Baltimore) 2024 May 17; 103 (20) : e38061.

Autor/es:Tao, Taotao (a)
Chen, Linkao (b)

institución:Tao, Taotao (a)
Chen, Linkao (b)

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe impreso

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1097/MD.0000000000038061

Paroxysmal sympathetic hyperexcitability after brain injury: A clinical analysis of case series.

Fuente:Medicine

Extracto: The etiology of PSH is complex. TBI may be the most common cause of PSH. Non-TBI may also be an important cause of PSH. Therefore, early identification, prevention and diagnosis are helpful for determining the prognosis and outcome of the disease.

Cita:Medicine (Baltimore) 2024 May 17; 103 (20) : e35375.

Autor/es:Li, Xingru (a)
Yang, Xinchen (b)

institución:(a) Department of Neurosurgery, The First Affiliated Hospital of Wannan Medical College (Yijishan Hospital of Wannan Medical College), Wuhu, China.
(b) Department of Neurosurgery, The Second Affiliated Hospital of Nanchang University, Nanchang, China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe impreso

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1097/MD.0000000000035375

The effect of amantadine treatment on neurological outcome and mortality in mechanically ventilated severe head trauma patients in intensive care unit.

Fuente:Medicine

Extracto: However, further research is needed to investigate this topic.

Cita:Medicine (Baltimore) 2024 May 17; 103 (20) : e38172.

Autor/es:Öner, Özlem (a)
Hanci, Volkan (b)

institución:(a) Anesthesiologist and Intensivist Neuroscience, Dokuz Eylül University Faculty of Medicine Department of Anesthesiology and Reanimation, Subdivision of Critical Care Medicine, İzmir, Turkey.
(b) Anesthesiologist and Intensivist, Dokuz Eylül University Faculty of Medicine Department of Anesthesiology and Reanimation, Subdivision of Critical Care Medicine, İzmir, Turkey.

Conflicto:The authors have no funding and conflicts of interest to disclose.

Formato:Informe impreso

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1097/MD.0000000000038172

Glycolic acid and D-lactate-putative products of DJ-1-restore neurodegeneration in FUS - and SOD1-ALS.

Fuente:Life Science Alliance

Extracto: Whereas these data point towards the necessity of individualized (gene-) specific therapy stratification, it also suggests common therapeutic targets across different neurodegenerative diseases characterized by mitochondrial depolarization.

Cita:Life Sci Alliance 2024 Aug; 7 (8)

Autor/es:Pal, Arun (a)
Grossmann, Dajana (b)

institución:(a) Division for Neurodegenerative Diseases, Department of Neurology, Technische Universität Dresden, Dresden, Germany.
(b) Dresden High Magnetic Field Laboratory (HLD-EMFL), Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Dresden, Germany.

Conflicto:A Hermann has received personal fees and non-financial support from Biogen and Desitin during the conduct of the study outside the submitted work. R Günther has received honoraria from Biogen as an advisory board member and for lectures and as a consultant and advisory board member from Hoffmann-La Roche. He also received travel expenses and research support from Biogen. F... F Pan-Montojo has a patent on the use of glycolic acid and D-lactate as neuroprotective treatment for neurodegenerative disease. In addition, F Pan-Montojo is the CEO and CSO of Neurevo GmbH, a biotech company developing glycolic acid and D-lactate as neuroprotective treatments for several neurological diseases. INSTITUTIONAL REVIEW BOARD STATEMENT: The performed procedures were in accordance with the Declaration of Helsinki (WMA, 1964) and approved by the Ethical Committee of the Technische Universität Dresden, Germany (EK 393122012 and EK 45022009). INFORMED CONSENT STATEMENT: Written informed consent was obtained from all participants including for publication of any research results.

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.26508/lsa.202302535

Integrated bioinformatics analysis for exploring potential biomarkers related to Parkinson's disease progression.

Fuente:Bmc Medical Genomics

Extracto: We identified PD-related molecular markers and ceRNA regulatory networks, providing new directions for PD diagnosis and treatment.

Claves:Dopaminergic neurons, Hub genes, Parkinson, ceRNA network, circRNA, s disease

Cita:BMC Med Genomics 2024 May 17; 17 (1) : 133.

Autor/es:Huang, Zhenchao (a)
Song, En'peng (b)

institución:(a) Department of Neurosurgery, Lingnan Hospital, Branch of The Third Affiliated Hospital of Sun Yat-Sen University, No 2693, Kaichuang Avenue, Huangpu District, Guangzhou, 510530, Guangdong, China. hzhench3@mail.sysu.edu.cn.
(b) Department of Neurosurgery, Lingnan Hospital, Branch of The Third Affiliated Hospital of Sun Yat-Sen University, No 2693, Kaichuang Avenue, Huangpu District, Guangzhou, 510530, Guangdong, China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12920-024-01885-9