Clinical applications of stem cell-derived exosomes.

Fuente:Signal Transduction and Targeted Therapy

Extracto: We recommend that future research combines wisdoms from surgeons, nanomedicine practitioners, and stem cell researchers in this relevant and intriguing research area.

Cita:Signal Transduct Target Ther 2024 Jan 12; 9 (1) : 17.

Autor/es:Tan, Fei (a)
Li, Xuran (b)

institución:(a) Department of ORL-HNS, Shanghai Fourth People's Hospital, and School of Medicine, Tongji University, Shanghai, China. iatrologist@163.com.
(b) Plasma Medicine and Surgical Implants Center, Tongji University, Shanghai, China. iatrologist@163.com.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1038/s41392-023-01704-0

UNCAN.eu: Toward a European Federated Cancer Research Data Hub.

UNCAN.eu: Toward a European Federated Cancer Research Data Hub.

Fuente:Cancer Discovery

Extracto: A workshop hosted in Heidelberg gathered European cancer experts to identify ongoing initiatives that may contribute to building this platform and discuss the governance and long-term evolution of a European Federated Cancer Data Hub.

Cita:Cancer Discov 2024 Jan 12; 14 (1) : 30-35.

Autor/es:Boutros, Michael (a)
Baumann, Michael (b)

institución:(a) German Cancer Research Center (DKFZ), Division of Signaling and Functional Genomics and Heidelberg University, Medical Faculty Heidelberg, Institute for Human Genetics, Heidelberg, Germany.
(b) DKFZ, Heidelberg, Germany.

Formato:Informe impreso

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1158/2159-8290.CD-23-1111

Increasing awareness for dementia risk reduction through a public awareness campaign in Denmark: A pre-post study.

Increasing awareness for dementia risk reduction through a public awareness campaign in Denmark: A pre-post study.

Fuente:Preventive Medicine

Extracto: This mass-media campaign did not increase overall awareness that dementia risk is partly modifiable. However, exposure to the campaign was associated with more awareness and willingness to take action to improve brain health. Future campaigns should tailor messages to specific subgroups to broaden the reach (e.g., males), co-create materials with the target group, and give special attention to the contribution of metabolic/cardiovascular risk factors to dementia risk.

Claves:Awareness, Brain health, Dementia, Health promotion, Knowledge, Lifestyle, Prevention, Public health, Risk factor, Risk reduction

Cita:Prev Med 2024 Feb; 179 : 107848.

Autor/es:Paauw, Dominique (a)
Heger, Irene (b)

institución:(a) Alzheimer Centre Limburg, Maastricht University Medical Center+, Maastricht, the Netherlands; Department of Psychiatry and Neuropsychology, Maastricht University, Maastricht, the Netherlands; School for Mental Health and Neuroscience (MHeNs), Maastricht University, Maastricht, the Netherlands.
(b) Alzheimer Centre Limburg, Maastricht University Medical Center+, Maastricht, the Netherlands; Department of Psychiatry and Neuropsychology, Maastricht University, Maastricht, the Netherlands; School for Mental Health and Neuroscience (MHeNs), Maastricht University, Maastricht, the Netherlands.

Conflicto:Declaration of competing interest None.

Formato:Informe impreso

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1016/j.ypmed.2024.107848

Limited Access to Aortic Valve Procedures in Socioeconomically Disadvantaged Areas.

Limited Access to Aortic Valve Procedures in Socioeconomically Disadvantaged Areas.

Fuente:Journal of The American Heart Association

Extracto: People living in high deprivation areas have less access to life-saving technologies, such as SAVR, and even moreso to device-intensive minimally invasive procedures such as TAVR and LC.

Claves:TAVR, aortic stenosis, aortic valve replacement, disparities, social determinants of health

Cita:J Am Heart Assoc 2024 Jan 16; 13 (2) : e030569.

Autor/es:David, Guy (a)
Bergman, Alon (b)

institución:(a) Department of Health Care Management, The Wharton School University of Pennsylvania Philadelphia PA.
(b) Department of Health Care Management, The Wharton School University of Pennsylvania Philadelphia PA.

Formato:Informe impreso

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1161/JAHA.123.030569

Don't be late! Timely identification of cognitive impairment in people with multiple sclerosis: a study protocol.

Don't be late! Timely identification of cognitive impairment in people with multiple sclerosis: a study protocol.

Fuente:Bmc Neurology

Tipo de trabajo:Estudio multicéntrico

Extracto: DISCUSSION: Validating the Multiple Screener(©) in PwMS and investigating cognition and its determinants will further facilitate early identification and adequate monitoring of cognitive decline in PwMS.

Claves:Cognitive impairment, Digital screening, Health-related quality of life, Innovation, Multiple sclerosis, Neuropsychology

Cita:BMC Neurol 2024 Jan 13; 24 (1) : 26.

Autor/es:Waskowiak, Pauline T (a)
de Jong, Brigit A (b)

institución:(a) MS Center Amsterdam, Medical Psychology, Vrije Universiteit Amsterdam, Amsterdam Neuroscience, Amsterdam UMC Location VUmc, De Boelelaan, 1118, Amsterdam, The Netherlands. p.t.waskowiak@amsterdamumc.nl.
(b) MS Center Amsterdam, Neurology, Vrije Universiteit Amsterdam, Amsterdam Neuroscience, Amsterdam UMC Location VUmc, Amsterdam, The Netherlands.

Conflicto:Pauline T. Waskowiak has no competing interests regarding publication. Brigit A. de Jong has no competing interests regarding publication. Bernard M.J. Uitdehaag has received research support and/or consultancy fees from Biogen Idec, Genzyme, Merck Serono, Novartis, Roche, Teva and Immunic Therapeutics. Shalina R.D. Saddal has no competing interests regarding publication. Jip Aarts has no competing interests regarding publication. Aïda A.M.... . Roovers has no competing interests regarding publication. Pim van Oirschot is employed by Sherpa BV. Vincent de Groot has no competing interests regarding publication. Frederieke G. Schaafsma has no competing interests regarding publication. Karin van der Hiele has no competing interests regarding publication. Marit F.L. Ruitenberg has no competing interests regarding publication. Menno M. Schoonheim serves on the editorial board of Neurology, Multiple Sclerosis Journal and Frontiers in Neurology, receives research support from the Dutch MS Research Foundation, Eurostars-EUREKA, ARSEP, Amsterdam Neuroscience, MAGNIMS and ZonMW (Vidi grant, project number 09150172010056) and has served as a consultant for or received research support from Atara Biotherapeutics, Biogen, Celgene/Bristol Meyers Squibb, EIP, Sanofi, MedDay and Merck. Guy A.M. Widdershoven has no competing interests regarding publication. Sabina van der Veen has no competing interests regarding publication. Esther C.F. Schippers has no competing interests regarding publication. Martin Klein has no competing interests regarding publication. Hanneke E. Hulst is an editor of the Multiple Sclerosis Journal controversies sections, receives research support from the Dutch MS Research Foundation and the Dutch Research Council. She has served as a consultant for or received research support from Atara Biotherapeutics, Biogen, Novartis, Celgene/Bristol Meyers Squibb, Sanofi Genzyme, MedDay and Merck BV.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12883-023-03495-x

Behavioral sciences applied to acute care teams: a research agenda for the years ahead by a European research network.

Behavioral sciences applied to acute care teams: a research agenda for the years ahead by a European research network.

Fuente:Bmc Health Services Research

Extracto: Based on research priorities within the BSAS community and the broader field of applied health sciences identified through this work, we advocate for the prioritization for funding in these areas.

Claves:Acute care, Research agenda, Surgery, Teamwork

Cita:BMC Health Serv Res 2024 Jan 13; 24 (1) : 71.

Autor/es:Keller, Sandra (a)
Jelsma, Judith G M (b)

institución:(a) Department of Visceral Surgery and Medicine, Bern University Hospital, Bern, Switzerland. sandra.keller@unibe.ch.
(b) Department for BioMedical Research (DBMR), Bern University, Bern, Switzerland. sandra.keller@unibe.ch.

Conflicto:RML receives per diem honoraria from Paedsim e.V. for interprofessional team training. NS is the director of the London Safety and Training Solutions Ltd, which offers training in patient safety, implementation solutions and human factors to healthcare organisations and the pharmaceutical industry. IvH is supported by a Senior Clinical Fellowship (802314N), Fund for Scientific Research – Flanders, Belgium. MdB, JJ,... J, SK, FT, JC, LKM, WE, NKS, KPH declare no competing interests.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12913-024-10555-6

Higher prevalence of coronary microvascular dysfunction in asymptomatic individuals with high levels of lipoprotein(a) with and without heterozygous familial hypercholesterolaemia.

Higher prevalence of coronary microvascular dysfunction in asymptomatic individuals with high levels of lipoprotein(a) with and without heterozygous familial hypercholesterolaemia.

Fuente:Atherosclerosis

Extracto: Coronary microvascular dysfunction is more prevalent in asymptomatic individuals with isolated Lp(a) elevation and in heterozygous FH both with and without high Lp(a) compared to healthy controls. Cholesterol-lowering treatment could potentially prevent the development of microvascular dysfunction.

Claves:Coronary flow reserve, Endothelial dysfunction, Familial hypercholesterolaemia, Microvascular dysfunction, Reactive hyperaemia index, lipoprotein(a)

Cita:Atherosclerosis 2024 Feb; 389 : 117439.

Autor/es:Wodaje, Tigist (a)
Mahdi, Ali (b)

institución:(a) Cardio Metabolic Unit, Department of Medicine Huddinge, Karolinska Institutet, Stockholm, Sweden; Department of Cardiology, Karolinska University Hospital, Stockholm, Sweden.
(b) Department of Cardiology, Karolinska University Hospital, Stockholm, Sweden; Division of Cardiology, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden.

Conflicto:Declaration of competing interest The authors declare the following financial interests/personal relationships which may be considered as potential competing interests: Jonas Brinck (JB) reports honoraria from Akcea Therapeutics, Amarin, Amgen, Bayer, Novartis and Sanofi, and research grants from Akcea Therapeutics, Amgen, and Sanofi outside of the submitted work. Bo Angelin (BA) consults for and receives grants from AstraZeneca and Albireo,... and an independent grant from Amgen. JB and BA as well as all other authors declare no competing interests regarding this work.

Formato:Informe impreso

Idioma:Inglés

País de fuente:Irlanda

Sitio web:http://dx.doi.org/10.1016/j.atherosclerosis.2023.117439

Palmitic acid-activated GPRs/KLF7/CCL2 pathway is involved in the crosstalk between bone marrow adipocytes and prostate cancer.

Palmitic acid-activated GPRs/KLF7/CCL2 pathway is involved in the crosstalk between bone marrow adipocytes and prostate cancer.

Fuente:Bmc Cancer

Extracto: PA-activated GPRs/KLF7/CCL2 pathway in BMA facilitates prostate cancer growth and metastasis.

Claves:Bone marrow adipocytes, GPRs/KLF7/CCL2, Palmitic acid, Prostate cancer

Cita:BMC Cancer 2024 Jan 15; 24 (1) : 75.

Autor/es:Wang, Jingzhou (a)
Liu, Jie (b)

institución:(a) Shihezi University School of Medicine, Bei-Er-Lu, Shihezi, 832000, Xinjiang, China.
(b) Laboratory of Xinjiang Endemic and Ethic Diseases, Shihezi University, Shihezi, 832000, Xinjiang, China.

Conflicto:The authors declare that they have no competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12885-024-11826-5

Don't be late! Postponing cognitive decline and preventing early unemployment in people with multiple sclerosis: a study protocol.

Don't be late! Postponing cognitive decline and preventing early unemployment in people with multiple sclerosis: a study protocol.

Fuente:Bmc Neurology

Tipo de trabajo:Estudio aleatorizado y controlado

Extracto: TRIAL REGISTRATION: Retrospectively registered at ClinicalTrials.gov with reference number NCT06068582 on 10 October 2023.

Claves:Cognition, Employment, Exercise, Health-related quality of life, Multiple sclerosis, Prevention

Cita:BMC Neurol 2024 Jan 15; 24 (1) : 28.

Autor/es:Aarts, Jip (a)
Saddal, Shalina R D (b)

institución:(a) Health, Medical and Neuropsychology Unit, Institute of Psychology, Faculty of Social Sciences, Leiden University, Wassenaarseweg 52, Leiden, 2333 AK, The Netherlands. j.aarts@fsw.leidenuniv.nl.
(b) Leiden Institute for Brain and Cognition, Leiden, The Netherlands. j.aarts@fsw.leidenuniv.nl.

Conflicto:JA, SS, JB, VG, BJ, MK, MR, FS, ES, SV, PW, GW, and KH have nothing to declare with respect to this study. BU has received research support and/or consultancy fees from Biogen Idec, Genzyme, Merck Serono, Novartis, Roche, Teva and Immunic Therapeutics. MS serves on the editorial board of Neurology, Multiple Sclerosis Journal and Frontiers in Neurology, receives research... support from the Dutch MS Research Foundation, Eurostars-EUREKA, ARSEP, Amsterdam Neuroscience, MAGNIMS and ZonMW (Vidi grant, project number 09150172010056) and has served as a consultant for or received research support from Atara Biotherapeutics, Biogen, Celgene/Bristol Meyers Squibb, EIP, Sanofi, MedDay and Merck. HH is an editor of the Multiple Sclerosis Journal controversies sections, receives research support from the Dutch MS Research Foundation and the Dutch Research Council. She has served as a consultant for or received research support from Atara Biotherapeutics, Biogen, Novartis, Celgene/Bristol Meyers Squibb, Sanofi Genzyme, MedDay and Merck BV.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12883-023-03513-y

Validation of overall survival extrapolations made by TLV in the assessment of cost-effectiveness of oncology drugs in Sweden - A pilot study comparing extrapolated and observed life-years gained.

Validation of overall survival extrapolations made by TLV in the assessment of cost-effectiveness of oncology drugs in Sweden - A pilot study comparing extrapolated and observed life-years gained.

Fuente:Journal of Medical Economics

Tipo de trabajo:Estudio clínico

Extracto: We conclude that it is feasible to validate OS extrapolations by comparing extrapolated and observed life-years. Even if survival extrapolations are reasonably accurate for the treatment group, this may still imply that extrapolations of LYs gained deviates to a larger extent. Follow-up studies on OS should be carried out to an increased extent to be able to validate, update and improve OS extrapolations in cost-effectiveness analysis of oncology drugs.

Claves:Cost-effectiveness, I10, I15, extrapolation, health technology assessment, oncology, overall survival, prediction

Cita:J Med Econ 2024 Jan-Dec; 27 (1) : 193-200.

Autor/es:Björnerstedt, Jonas (a)
Almqvist, Hannah (b)

institución:(a) Department of Economics, Södertörn University, Huddinge, Sweden.
(b) Dental and Pharmaceutical Benefits Agency (TLV), Stockholm, Sweden.

Formato:Informe impreso

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1080/13696998.2024.2304459

Global perspectives of determinants influencing HPV vaccine introduction and scale-up in low- and middle-income countries.

Global perspectives of determinants influencing HPV vaccine introduction and scale-up in low- and middle-income countries.

Fuente:Plos One

Extracto: As LMICs introduce HPV vaccines into their national immunization programs and develop plans for scaling up vaccination efforts, strategic approaches to communications and advocacy will also be needed to successfully meet coverage targets.

Cita:PLoS One 2024; 19 (1) : e0291990.

Autor/es:Guillaume, Dominique (a)
Waheed, Dur-E-Nayab (b)

institución:(a) International Vaccine Access Center, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, United States of America.
(b) Jhpiego, A Johns Hopkins University Affiliate, Baltimore, Maryland, United States of America.

Conflicto:The authors have no conflict of interest to declare.

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1371/journal.pone.0291990

A Systematic Review of Health Management Mobile Applications in COVID-19 Pandemic: Features, Advantages, and Disadvantages.

A Systematic Review of Health Management Mobile Applications in COVID-19 Pandemic: Features, Advantages, and Disadvantages.

Fuente:Biomed Research International

Tipo de trabajo:Revisión sistemática

Extracto: The study results showed that mobile applications have been effective in controlling the prevalence of COVID-19 by identifying virus-infested environments, identifying and monitoring infected people, controlling social distancing, and maintaining quarantine. It is suggested that usability, ethical and security considerations, protection of personal information, and privacy of users be considered in application design and development.

Cita:Biomed Res Int 2024; 2024 : 8814869.

Autor/es:Garavand, Ali (a)
Ameri, Fatemeh (b)

institución:(a) Health Information Management, Department of Health Information Technology, School of Allied Medical Sciences, Lorestan University of Medical Sciences, Khorramabad, Iran.
(b) Health Information Technology, Student Research Committee, Department of Health Information Technology, School of Paramedical Sciences, Mashhad University of Medical Sciences, Mashhad, Iran.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1155/2024/8814869

Transforming malaria prevention and control: the prospects and challenges of gene drive technology for mosquito management.

Transforming malaria prevention and control: the prospects and challenges of gene drive technology for mosquito management.

Fuente:Annals of Medicine

Extracto: Thus, the practical application raises significant ethical and regulatory concerns for further research and risk assessment, including the risk of gene drive spreading to nontarget species in the wider theatre of biodiverse species.

Claves:CRISP R, Malaria control, gene drive, mosquito management

Cita:Ann Med 2023; 55 (2) : 2302504.

Autor/es:Tajudeen, Yusuf Amuda (a)
Oladipo, Habeebullah Jayeola (b)

institución:(a) Department of Epidemiology and Medical Statistics, Faculty of Public Health, College of Medicine, University of Ibadan, Ibadan, Nigeria.
(b) Department of Microbiology, Faculty of Life Sciences, University of Ilorin, Ilorin, Nigeria.

Conflicto:No potential conflict of interest was reported by the author(s).

Formato:Informe impreso

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1080/07853890.2024.2302504

Can instrumentation kinematics affect postoperative pain and substance P levels? A randomized controlled trial.

Can instrumentation kinematics affect postoperative pain and substance P levels? A randomized controlled trial.

Fuente:Bmc Oral Health

Extracto: Our findings suggest that continuous rotation kinematics in root canal preparation leads to a considerable reduction in SP expression and POP. TRIAL REGISTRATION: The study protocol was retrospectively registered on the www. CLINICALTRIALS: gov database (NCT06081335) at (13/10/2023) after the approval of the Ethics Committee, Faculty of Dentistry, Ain Shams University (FDASU-RecIM012135).

Claves:Continuous rotation, Postoperative pain, Reciprocation, Substance P, Symptomatic apical periodontitis

Cita:BMC Oral Health 2024 Jan 17; 24 (1) : 102.

Autor/es:Abdel-Baset, Salma Talaat (a)
Fahmy, Sarah Hossam (b)

institución:(a) Department of Endodontics, Faculty of Dentistry, Ain Shams University, Cairo, Egypt.
(b) Department of Endodontics, Faculty of Dentistry, Ain Shams University, Cairo, Egypt.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12903-024-03882-x

Changes to Public Health Surveillance Methods Due to the COVID-19 Pandemic

Changes to Public Health Surveillance Methods Due to the COVID-19 Pandemic

Fuente:Jmir Public Health and Surveillance

Tipo de trabajo:Revisión

Extracto: The COVID-19 pandemic accelerated advancements in surveillance and the adoption of new technologies, especially for digital and wastewater surveillance methods. Given the investments in these systems, further applications for public health surveillance are likely. The literature for surveillance methods was dominated by surveillance of infectious diseases, particularly COVID-19. A substantial amount of literature on the ethical, legal, security, and equity implications of these emerging surveillance methods also points to a need for cautious consideration of potential harm.

Claves:COVID-19, big data, decision making, digital surveillance, ethics, infodemiology, mobility tracking, public health, public health surveillance, screening, surveillance, wastewater

Cita:JMIR Public Health Surveill 2024 Jan 19; 10 : e49185.

Autor/es:Clark, Emily C (a)
Neumann, Sophie (b)

institución:(a) National Collaborating Centre for Methods and Tools, Hamilton, ON, Canada.
(b) National Collaborating Centre for Methods and Tools, Hamilton, ON, Canada.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Canadá

Sitio web:http://dx.doi.org/10.2196/49185

Redefining Virtual Assistants in Health Care: The Future With Large Language Models.

Redefining Virtual Assistants in Health Care: The Future With Large Language Models.

Fuente:Journal of Medical Internet Research

Extracto: We need a robust interdisciplinary collaboration to navigate the complexities of safely and effectively integrating LLMs into health care applications, ensuring that these emerging technologies align with the diverse needs and ethical considerations of the health care domain.

Claves:chatbots, conversational agents, health care, large language models, virtual assistants, voice assistants

Cita:J Med Internet Res 2024 Jan 19; 26 : e53225.

Autor/es:chatbots, conversational agents, health care, large language models, virtual assistants, voice assistants

institución:(a) The Abigail Wexner Reseach Institute at Nationwide Children's Hospital, Columbus, OH, United States.
(b) The Ohio State University College of Medicine, Columbus, OH, United States.

Conflicto:Conflicts of Interest: ES serves on the editorial board of JMIR Publications.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Canadá

Sitio web:http://dx.doi.org/10.2196/53225

Access to cancer clinical trials for racialised older adults

Access to cancer clinical trials for racialised older adults

Fuente:Bmj Open

Tipo de trabajo:Revisión

Extracto: The findings of the scoping review will be submitted for publication in a peer-reviewed journal and presentation at international conferences.

Claves:GERIATRIC MEDICINE, Health Equity, ONCOLOGY

Cita:BMJ Open 2024 Jan 19; 14 (1) : e074191.

Autor/es:Li, Vivian (a)
Alibhai, Shabbir M H (b)

institución:(a) Lawrence S. Bloomberg Faculty of Nursing, University of Toronto, Toronto, Ontario, Canada.
(b) Department of Medicine, University Health Network, Toronto, Ontario, Canada.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1136/bmjopen-2023-074191

Resistin in endocrine pancreas of sheep: Presence and expression related to different diets.

Resistin in endocrine pancreas of sheep: Presence and expression related to different diets.

Fuente:General and Comparative Endocrinology

Extracto: Furthermore, the RETN expression is not influenced by food supplementation and thus is not affected by diet.

Claves:Adipokines, Animal welfare, Immunohistochemistry, Ovine, Pancreatic islets, Real-time PCR

Cita:Gen Comp Endocrinol 2024 Mar 1; 348 : 114452.

Autor/es:Maranesi, Margherita (a)
Palmioli, Elisa (b)

institución:(a) Department of Veterinary Medicine, University of Perugia, Via San Costanzo 4, 06126 Perugia, IT, Italy. Electronic address: margherita.maranesi@unipg.it.
(b) Department of Veterinary Medicine, University of Perugia, Via San Costanzo 4, 06126 Perugia, IT, Italy; Department of Philosophy, Social Sciences, and Education, PhD Course in "Ethics of Communication, Scientific Research and Technological Innovation" Medical-Health Curriculum, University of Perugia, Piazza G. Ermini, 1, 06123 Perugia, IT, Italy. Electronic address: elisa.palmioli@studenti.unipg.it.

Conflicto:Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Formato:Informe impreso

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1016/j.ygcen.2024.114452

Population-Based Biobanking.

Population-Based Biobanking.

Fuente:Genes

Extracto: Despite the tremendous progress made so far, some major challenges to population-based biobanking still remain, including the need to develop strategies for the long-term sustainability of biobanks, the handling of incidental findings, and the linkage of sample-related and sample-derived data to other relevant resources.

Claves:biobanking, biomarker, biosample, clinical routine, cohort study, governance, health data, phenotype, public involvement, sustainability

Cita:Genes (Basel) 2024 Jan 3; 15 (1)

Autor/es:Lieb, Wolfgang (a)
Strathmann, Eike A (b)

institución:(a) Institute of Epidemiology and Biobank Popgen, Kiel University, University Hospital Schleswig-Holstein, Campus Kiel, 24105 Kiel, Germany.
(b) German Centre for Lung Research (DZL), Airway Research Centre North (ARCN), 22927 Großhansdorf, Germany.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3390/genes15010066

Embers of the Past: Early Childhood Traumas Interact with Variation in P2RX7 Gene Implicated in Neuroinflammation on Markers of Current Suicide Risk.

Embers of the Past: Early Childhood Traumas Interact with Variation in P2RX7 Gene Implicated in Neuroinflammation on Markers of Current Suicide Risk.

Fuente:International Journal of Molecular Sciences

Extracto: Our results suggest that P2RX7 variation may mediate the effect of early childhood adversities and traumas on later emergence of suicide risk.

Claves:GxE interaction, P2RX7, childhood adversities, neuroinflammation, recent life events, stress, suicide

Cita:Int J Mol Sci 2024 Jan 10; 25 (2)

Autor/es:Kristof, Zsuliet (a)
Gal, Zsofia (b)

institución:(a) Department of Psychiatry and Psychotherapy, Semmelweis University, Balassa utca 6, 1082 Budapest, Hungary.
(b) Laboratory of Molecular Pharmacology, HUN-REN Institute of Experimental Medicine, Szigony utca 43, 1083 Budapest, Hungary.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3390/ijms25020865