Characterizing poorly controlled type 2 diabetes using (1)H-NMR metabolomics.

Fuente:Metabolomics Official Journal of The Metabolomic Society

Extracto: These results indicate that inhibited cellular glucose uptake in poorly controlled type 2 diabetes significantly affects energy-producing pathways, leading to apoptosis and/or autophagy, ultimately contributing to kidney and mild liver damage. The study also suggests poor dietary compliance as a cause of the patient's uncontrolled glycemic state. Collectively these findings offer a first-time comprehensive overview of urine metabolic changes in poorly controlled type 2 diabetes and its association with secondary diseases, offering potential insights for more targeted treatment strategies to prevent disease progression, treatment efficacy, and diet/treatment compliance.

Claves:Metabolomics, Poorly controlled type 2 diabetes, Proton nuclear magnetic resonance, Urine

Cita:Metabolomics 2024 May 11; 20 (3) : 54.

Autor/es:Theron, Isabella J (a)
Mason, Shayne (b)

institución:(a) Human Metabolomics, Department of Biochemistry, Faculty of Natural and Agricultural Sciences, North-West University, Potchefstroom, South Africa.
(b) Human Metabolomics, Department of Biochemistry, Faculty of Natural and Agricultural Sciences, North-West University, Potchefstroom, South Africa.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1007/s11306-024-02127-w

Long-term impact of COVID-19 pandemic on secular changes in metabolic parameters in Japanese workers Tokushima Cohort Study.

Fuente:The Journal of Medical Investigation Jmi

Extracto: Our findings suggest that there was an apparent metabolic impact of the COVID-19 pandemic on DBP increment in Japanese workers. In addition, COVID-19 may have influenced males and females differently in relation to glucose metabolism and anthropometric measurements related to obesity / adiposity. J. Med. Invest. 71 : 47-53, February, 2024.

Claves:Covid-19, diastolic blood pressure, pandemic, prospective study, secular change

Cita:J Med Invest 2024; 71 (1.2) : 47-53.

Autor/es:Hata, Akiko (a)
Funaki, Makoto (b)

institución:(a) Clinical Research Center for Diabetes, Tokushima University Hospital, Tokushima, Japan (AH, MF).
(b) Clinical Research Center for Diabetes, Tokushima University Hospital, Tokushima, Japan (AH, MF).

Formato:Informe impreso

Idioma:Inglés

País de fuente:Japón

Sitio web:http://dx.doi.org/10.2152/jmi.71.47

Reproductive and fetal outcomes in women with epilepsy

Fuente:The Journal of Maternal-fetal & Neonatal Medicine The Official Journal of The European Association of Perinatal Medicine, The Federation of Asia and Oceania Perinatal Societies, The International Society of Perinatal Obstetricians

Tipo de trabajo:Revisión sistemática

Extracto: Pregnant women affected by epilepsy encounter a higher risk of adverse obstetric outcomes and fetal complications. Therefore, it is crucial to develop appropriate prevention and intervention strategies prior to or during pregnancy to minimize the negative impacts of epilepsy on maternal and fetal health.

Claves:Women, epilepsy, fetal outcomes, obstetrical outcomes, pregnancy

Cita:J Matern Fetal Neonatal Med 2024 Dec; 37 (1) : 2351196.

Autor/es:Kuang, Huimin (a)
Li, Yixun (b)

institución:(a) Department of Neurology, First Affiliated Hospital of Guangxi Medical University, Nanning, China.
(b) Department of Radiology, Guangxi International Zhuang Medical Hospital, Nanning, China.

Formato:Informe impreso

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1080/14767058.2024.2351196

Comparison of the Oral Hygiene Status in Children With and Without Juvenile Diabetes - A Comparative Study.

Fuente:Indian Journal of Dental Research Official Publication of Indian Society For Dental Research

Extracto: No statistically significant differences were noted in the gingival condition and dental caries experience between the children with and without juvenile diabetes (P = 0.820; 0.504; 0.422). However, the overall oral hygiene status was found to be poor in children with juvenile diabetes (P = 0.003). No significant differences were observed in the gingival status and the dental caries prevalence between the two groups.

Cita:Indian J Dent Res 2023 Oct 1; 34 (4) : 410-412.

Autor/es:Govindaraju, Lavanya (a)
Gurunathan, Deepa (b)

institución:(a) Department of Pedodontics, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, India.
(b) Department of Pedodontics, Saveetha Dental College and Hospital, Saveetha University, Chennai, Tamil Nadu, India.

Formato:Informe impreso

Idioma:Inglés

País de fuente:India

Sitio web:http://dx.doi.org/10.4103/ijdr.ijdr_1142_21

Research to Improve Clinical Care in Family Medicine: Big Data, Telehealth, Artificial Intelligence, and More.

Fuente:Journal of The American Board of Family Medicine Jabfm

Extracto: Several articles report on inappropriate testing for common health problems; are you following recommendations for ordering Pulmonary Function Tests, mt-sDNA for colon cancer screening, and HIV testing?

Cita:J Am Board Fam Med 2024 Mar-Apr; 37 (2) : 161-164.

Autor/es:Bowman, Marjorie A (a)
Seehusen, Dean A (b)

institución:Bowman, Marjorie A (a)
Seehusen, Dean A (b)

Conflicto:Conflict of interest: The authors are editors of the JABFM.

Formato:Informe impreso

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.3122/jabfm.2024.240050R0

Empowering Low-Income Patients with Home Blood Pressure Monitors to Improve Hypertension Control.

Fuente:Journal of The American Board of Family Medicine Jabfm

Tipo de trabajo:Revisión

Extracto: DISCUSSION: The provision of free home BP monitors to low-income patients may feasibly and effectively improve BP control and therapy adherence.

Claves:Blood Pressure, Hypertension, Minority Health, Patient Adherence, Primary Health Care, Prospective Studies, Surveys and Questionnaires, Telemedicine, Vulnerable Populations

Cita:J Am Board Fam Med 2024 Mar-Apr; 37 (2) : 187-195.

Autor/es:Sarkar, Arindam (a)
Nwokocha, Chinwe (b)

institución:(a) From the Baylor College of Medicine, Department of Family and Community Medicine, Houston TX (AS, CN, SGN, LG).
(b) From the Baylor College of Medicine, Department of Family and Community Medicine, Houston TX (AS, CN, SGN, LG).

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe impreso

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.3122/jabfm.2023.230357R1

The Role of Telehealth in Improving Care Connections and Outcomes for Community Health Center Patients with Diabetes.

Fuente:Journal of The American Board of Family Medicine Jabfm

Extracto: Telehealth can be a highly effective, patient-centered form of care for people with diabetes. Telehealth can play a critical role in keeping vulnerable patients with diabetes connected to their care team and involved in care and may be an important tool for reducing health disparities.

Claves:Chronic Disease, Community Health Centers, Continuity of Patient Care, Diabetes Mellitus, Health Care Disparities, Health Inequities, Linear Regression, Patient Care Team, Patient-Centered Care, Quality Improvement, Retrospective Studies, Social Determinants of Health, Telemedicine

Cita:J Am Board Fam Med 2024 Mar-Apr; 37 (2) : 206-214.

Autor/es:Simon, Jodi (a)
Eggleston, Alice (b)

institución:(a) From the AllianceChicago, Chicago, IL (JS, AE, DB, PD, DTL, T-YY, JM); RUSH University Medical Center, Chicago, IL (PD); AllianceChicago, Northwestern University Feinberg School of Medicine, Division of General Internal Medicine, Chicago, IL (DTL). jsimon@alliancechicago.org.
(b) From the AllianceChicago, Chicago, IL (JS, AE, DB, PD, DTL, T-YY, JM); RUSH University Medical Center, Chicago, IL (PD); AllianceChicago, Northwestern University Feinberg School of Medicine, Division of General Internal Medicine, Chicago, IL (DTL).

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe impreso

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.3122/jabfm.2023.230338R1

Self-Management Support Improves Diabetes Outcomes Without Exacerbating Inequities.

Fuente:Journal of The American Board of Family Medicine Jabfm

Tipo de trabajo:Estudio clínico aleatorizado

Extracto: This suggests CTH-like programs can enhance diabetes outcomes in community health centers without exacerbating inequities for those with low health literacy.

Claves:Body Mass Index, California, Community Health Centers, Community-Based Research, Diabetes Mellitus, Endocrinology, Family Medicine, Hb A1c, Health Inequities, Health Literacy, Lifestyle, Patient Education, Patient-Centered Care, Primary Health Care, Regression Analysis, Self-Management, Surveys and Questionnaires

Cita:J Am Board Fam Med 2024 Mar-Apr; 37 (2) : 303-308.

Autor/es:Krishnakumar, Devika (a)
Hessler Jones, Danielle (b)

institución:(a) From the Department of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA (DK); Department of Family and Community Medicine, University of California, San Francisco, San Francisco, CA (DHS, MBP). devikakk07@gmail.com.
(b) From the Department of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA (DK); Department of Family and Community Medicine, University of California, San Francisco, San Francisco, CA (DHS, MBP).

Conflicto:Conflict of interest: None.

Formato:Informe impreso

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.3122/jabfm.2023.230324R1

Prescription and Dispensation of QT-Prolonging Medications in Individuals Receiving Hemodialysis.

Prescription and Dispensation of QT-Prolonging Medications in Individuals Receiving Hemodialysis.

Fuente:Jama Network Open

Extracto: AND RELEVANCE: In this cross-sectional study, QT-prolonging medications for individuals with dialysis-dependent kidney failure were commonly prescribed by nonnephrology clinicians and from nonacute settings. Prescriptions for potentially interacting medications often originated from different prescribers. Strategies aimed at minimizing high-risk medication-prescribing practices in the population undergoing dialysis are needed.

Cita:JAMA Netw Open 2024 Apr 1; 7 (4) : e248732.

Autor/es:Wang, Virginia (a)
Wang, Chin-Hua Lily (b)

institución:(a) Department of Population Health Sciences, Duke University School of Medicine, Durham, North Carolina.
(b) Center of Innovation to Accelerate Discovery and Practice Transformation, Durham Veterans Affairs Medical Center, Durham, North Carolina.

Conflicto:Conflict of Interest Disclosures: Dr V. Wang reported receiving grants from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), National Institutes of Health (NIH); the Patient-Centered Outcomes Research Institute (PCORI); the Department of Veterans Affairs; the Robert Wood Johnson Foundation; and the National Committee for Quality Assurance outside the submitted work. Dr Assimon reported receiving honoraria from... the American Society of Nephrology and the International Society of Nephrology outside the submitted work and holding stock options in Aetion, Inc. Dr Pun reported receiving grants for investigator-initiated research from Medtronic, personal fees for research consulting from Fresenius Medical Care North America, and speaker honoraria from the National Kidney Foundation outside the submitted work. Dr Winkelmayer reported receiving personal fees from Actos, Akebia, Ardelyx, AstraZeneca, Bayer, Boehringer Ingelheim, Cadrenal, GSK, Eli Lilly, Merck, Natera, Novartis, Otsuka, Pharmacosmos, Unicycive, Vera, and Zydus outside the submitted work. Dr Flythe reported receiving grants from the NIDDK, NIH, and the PCORI during the conduct of the study and receiving funding from the Fresenius Medical Care Medical Advisory Board outside the submitted work. No other disclosures were reported.

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1001/jamanetworkopen.2024.8732

Pharmacotherapy and clinical outcomes of hospitalized COVID-19 patients in Chile during the first wave of pandemic.

Pharmacotherapy and clinical outcomes of hospitalized COVID-19 patients in Chile during the first wave of pandemic.

Fuente:Revista Medica de Chile

Tipo de trabajo:Guía

Extracto: The patterns of use of drugs to treat COVID-19 in Chile during the first wave of the pandemic were very dynamic and followed the international, evidence-based guidelines. The low mortality rate indicates that the clinical management of hospitalized patients was adequate.

Cita:Rev Med Chil 2023 May; 151 (5) : 541-550.

Autor/es:Muñoz, Daniel (a)
Cano, Catalina (b)

institución:(a) Instituto de Farmacia, Facultad de Ciencias, Universidad Austral de Chile, Valdivia, Chile.
(b) Escuela de Química y Farmacia, Facultad de Medicina, Universidad Andrés Bello, Santiago, Chile.

Formato:Informe impreso

Idioma:Inglés

País de fuente:Chile

Sitio web:http://dx.doi.org/10.4067/s0034-98872023000500541

[MALA

Fuente:Revista Medica de Chile

Tipo de trabajo:Revisión

Extracto: The analysis will be based on the experience of a series of cases of metformin-associated lactic acidosis treated at a hospital clinical center in Chile.

Cita:Rev Med Chil 2023 May; 151 (5) : 618-627.

Autor/es:Ávila, Eduardo (a)
Roessler B, Eric (b)

institución:(a) Escuela de Medicina, Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile.
(b) Escuela de Medicina, Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile.

Formato:Informe impreso

Idioma:spa

País de fuente:Chile

Sitio web:http://dx.doi.org/10.4067/s0034-98872023000500618

[Langerhans histiocytosis and panhypopituitarism in adults. Case report].

Fuente:Revista Medica de Chile

Extracto: The treatment consisted of maxillobuccofacial defocusing, hormonal supplementation, chemotherapy, and radiotherapy with favorable evolution.

Cita:Rev Med Chil 2023 May; 151 (5) : 659-664.

Autor/es:Carvajal Moya, Cindy (a)
Díaz Aracena, Jesús (b)

institución:(a) Medicina Interna, Hospital Regional Leonardo Guzmán, Universidad de Antofagasta, Antofagasta, Chile.
(b) Universidad de Antofagasta, Antofagasta, Chile.

Formato:Informe impreso

Idioma:spa

País de fuente:Chile

Sitio web:http://dx.doi.org/10.4067/s0034-98872023000500659

Clusters from chronic conditions in the Danish adult population.

Clusters from chronic conditions in the Danish adult population.

Fuente:Plos One

Extracto: Our work constitutes a step in the process of characterizing multimorbidity populations, leading to increased comprehension of the nature of multimorbidity, and towards potential applications to individual-based care, prevention, the development of clinical guidelines, and population management.

Cita:PLoS One 2024; 19 (4) : e0302535.

Autor/es:Stockmarr, Anders (a)
Frølich, Anne (b)

institución:(a) Department of Applied Mathematics and Computer Science, Technical University of Denmark, Lyngby, Denmark.
(b) Innovation and Research Centre for Multimorbidity, Slagelse Hospital, Slagelse, Denmark.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1371/journal.pone.0302535

Prednisone use, disease activity and the occurrence of hyperglycaemia and diabetes in patients with early rheumatoid arthritis: a 10-year subanalysis of the BeSt study.

Prednisone use, disease activity and the occurrence of hyperglycaemia and diabetes in patients with early rheumatoid arthritis: a 10-year subanalysis of the BeSt study.

Fuente:Rmd Open

Extracto: In non-diabetic early RA patients, the use of prednisone was not associated with developing hyperglycaemia or diabetes. However, high DAS increased the risk of diabetes. Potential risks associated with prednisone use may have been mitigated by its effect on DAS.

Claves:Antirheumatic Agents, Arthritis, Rheumatoid, Glucocorticoids

Cita:RMD Open 2024 Apr 30; 10 (2)

Autor/es:van der Pol, Joy Ardjuna (a)
Allaart, Cornelia F (b)

institución:(a) Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands j.a.van_der_pol@lumc.nl.
(b) Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1136/rmdopen-2024-004246

Reduced Immunogenicity of COVID-19 Vaccine in Obese Patients with Type 2 Diabetes: A Cross-Sectional Study.

Reduced Immunogenicity of COVID-19 Vaccine in Obese Patients with Type 2 Diabetes: A Cross-Sectional Study.

Fuente:Acta Medica Okayama

Extracto: Obese patients with type 2 diabetes may have attenuated vaccine efficacy and require additional vaccination; continuous infection control should be considered in such patients.

Claves:COVID-19, obesity, type 2 diabetes, vaccination

Cita:Acta Med Okayama 2024 Apr; 78 (2) : 185-191.

Autor/es:Takahashi, Hiroko (a)
Eguchi, Jun (b)

institución:(a) Department of Nephrology, Rheumatology, Endocrinology, and Metabolism, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences.
(b) Department of Nephrology, Rheumatology, Endocrinology, and Metabolism, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences.

Conflicto:No potential conflict of interest relevant to this article was reported.

Formato:Informe impreso

Idioma:Inglés

País de fuente:Japón

Sitio web:http://dx.doi.org/10.18926/AMO/66927

Prediction and causal inference of hyperuricemia using gut microbiota.

Prediction and causal inference of hyperuricemia using gut microbiota.

Fuente:Scientific Reports

Extracto: Our results suggest abundant Collinsella in the gut can increase blood UA levels.

Cita:Sci Rep 2024 Apr 30; 14 (1) : 9901.

Autor/es:Miyajima, Yuna (a)
Karashima, Shigehiro (b)

institución:(a) Department of Clinical Laboratory Science, Faculty of Health Sciences, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Kanazawa, Japan.
(b) Institute of Liberal Arts and Science, Kanazawa University, Kakuma, Kanazawa, Ishikawa, 920-1192, Japan. skarashima@staff.kanazawa-u.ac.jp.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1038/s41598-024-60427-6

Association of periodontal disease with gestational diabetes mellitus among postpartum women at a private tertiary care hospital of Karachi, Pakistan: a cross-sectional study.

Fuente:Scientific Reports

Extracto: Women who are overweight or tend to gain weight should be closely monitored and guided to take dietary measures.

Claves:Gestational diabetes, Gingivitis, Periodontal disease, Periodontitis, Pregnancy

Cita:Sci Rep 2024 Apr 30; 14 (1) : 9951.

Autor/es:Jamal, Wafa Zehra (a)
Khan, Farhan Raza (b)

institución:(a) Department of Community Health Sciences, Aga Khan University, Karachi, Pakistan. wafa.jamal2@aku.edu.
(b) Department of Surgery, Aga Khan University, Karachi, Pakistan.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1038/s41598-024-60659-6

NKX2-2 based nuclei sorting on frozen human archival pancreas enables the enrichment of islet endocrine populations for single-nucleus RNA sequencing.

NKX2-2 based nuclei sorting on frozen human archival pancreas enables the enrichment of islet endocrine populations for single-nucleus RNA sequencing.

Fuente:Bmc Genomics

Extracto: Our work fills a technological gap and helps to unleash frozen archival pancreatic tissues for molecular profiling targeting the endocrine population. This study opens doors to retrospective mappings of endocrine cell dynamics in pancreatic tissues of complex histopathology. We expect that our protocol is applicable to enrich nuclei for transcriptomics studies from various populations in different types of frozen archival tissues.

Claves:Endocrine population enrichment, Fluorescence-activated nuclei sorting (FANS), Frozen archival human pancreas, Islets, NKX2-2, Single-nucleus RNA-seq

Cita:BMC Genomics 2024 Apr 30; 25 (1) : 427.

Autor/es:Xie, Gengqiang (a)
Toledo, Maria Pilar (b)

institución:(a) Department of Biomedical Sciences, College of Medicine, Florida State University, 1115 West Call Street, Tallahassee, FL, 32306, USA.
(b) Department of Biomedical Sciences, College of Medicine, Florida State University, 1115 West Call Street, Tallahassee, FL, 32306, USA.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12864-024-10335-w

High prevalence of diabetes among young First Nations Peoples with metabolic dysfunction-associated steatotic liver disease: a population-based study in Australia.

High prevalence of diabetes among young First Nations Peoples with metabolic dysfunction-associated steatotic liver disease: a population-based study in Australia.

Fuente:International Journal For Equity in Health

Extracto: This study provides the first population-based epidemiological data on MASLD in First Nations Australians. The high prevalence of diabetes (that is associated with advanced fibrosis and liver disease mortality) among young First Nations Peoples with MASLD raises concern about future risk of progressive liver disease in this patient population. These data highlight the importance of early identification of MASLD, and providing culturally appropriate intervention to reduce disease progression in parallel with the management of cardiometabolic comorbidities.

Claves:Cirrhosis, Epidemiology, NAFLD, Population, Type 2 diabetes

Cita:Int J Equity Health 2024 Apr 30; 23 (1) : 84.

Autor/es:Valery, Patricia C (a)
Roche, Shruti (b)

institución:(a) Cancer & Chronic Disease Research Group, QIMR Berghofer Medical Research Institute, 300 Herston Road, 4006, Herston, QLD, Australia. patricia.valery@qimrberghofer.edu.au.
(b) The University of Queensland, St Lucia, QLD, Australia. patricia.valery@qimrberghofer.edu.au.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12939-024-02153-z

Prevalence of thyroid dysfunction and associated factors among adult type 2 diabetes mellitus patients, 2000-2022

Prevalence of thyroid dysfunction and associated factors among adult type 2 diabetes mellitus patients, 2000-2022

Fuente:Systematic Reviews

Tipo de trabajo:Revisión sistemática

Extracto: The current systematic review and meta-analysis showed that the TD's pooled prevalence was relatively higher than the general population. Therefore, regular screening of TD should be done for T2DM patients.

Claves:Factors, Meta analysis, Systematic review, Thyroid Dysfunction, Type two Diabetes mellitus

Cita:Syst Rev 2024 Apr 30; 13 (1) : 119.

Autor/es:Hadgu, Rishan (a)
Worede, Abebaw (b)

institución:(a) Department of Medical Laboratory Science, College of Medicine and Health Sciences, Arba Minch University, P.O. Box 21, Arba Minch, Ethiopia. richohadgu@gmail.com.
(b) Department of Clinical Chemistry, School of Biomedical and Laboratory Sciences, College of Medicine and Health Sciences, University of Gondar, P.O. Box 196, Gondar, Ethiopia.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s13643-024-02527-y