Textos Completos Autorizados

Diabetología
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Con una o todas las palabras
(escribir en inglés)
 
Ej.1: Adipokines Ej.2: Adipokines or Musculoskeletal
Con la frase exacta
(inglés)

Ej.3: Adipokines and Cardiovascular Systems
Con todas de las palabras
(inglés)

Ej.4: Adipokines and Cardiovascular and Systems
Sin las palabras
(inglés)

Ej.5: not Cardiovascular Systems
Frontiers in public health
Selección SIIC: 23 Mayo, 2024
Frontiers in public health

Predicting the prevalence of type 2 diabetes in Brazil: a modeling study.

Predicting the prevalence of type 2 diabetes in Brazil: a modeling study.

Fuente:Frontiers in Public Health

Extracto: The model predicts an increase in the prevalence of type 2 diabetes in Brazil. Even with ambitious targets to reduce obesity prevalence, type 2 diabetes in Brazil will continue to have a large impact on Brazilian public health.

Claves:demographic changes, modeling, obesity trends, projection, target strategies, type 2 diabetes prevalence

Cita:Front Public Health 2024; 12 : 1275167.

Autor/es:Moreira, Patrícia Vasconcelos Leitão (a)
de Arruda Neta, Adélia da Costa Pereira (b)

institución:(a) Department of Nutrition, Federal University of Paraiba, João Pessoa, Paraíba, Brazil.
(b) Department of Nutrition, Federal University of Paraiba, João Pessoa, Paraíba, Brazil.

Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3389/fpubh.2024.1275167

Frontiers in endocrinology
Selección SIIC: 23 Mayo, 2024
Frontiers in endocrinology

Discovery of metastases in thyroid cancer and "benign metastasizing goiter": a historical note.

Discovery of metastases in thyroid cancer and "benign metastasizing goiter": a historical note.

Fuente:Frontiers in Endocrinology

Extracto: Even though Jean Claude Recamier described metastases in 1829, secondary lesions on various organs in patients with thyroid malignancies were not themselves considered malignant until 1876.

Claves:cancer, goiter, history, malignancies, metastases, thyroid

Cita:Front Endocrinol (Lausanne) 2024; 15 : 1354750.

Autor/es:Kushchayev, Sergiy (a)
Kushchayeva, Yevgeniya (b)

institución:(a) Diabetes and Endocrinology Center, University of South Florida, Tampa, FL, United States.
(b) Department of Radiology, Moffitt Cancer Center, Tampa, FL, United States.

Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3389/fendo.2024.1354750

Selección SIIC: 23 Mayo, 2024

Temporal alteration of serum bilirubin levels and its renoprotective effects in diabetic kidney disease: exploring the hormonal mechanisms.

Temporal alteration of serum bilirubin levels and its renoprotective effects in diabetic kidney disease: exploring the hormonal mechanisms.

Fuente:Frontiers in Endocrinology

Extracto: The findings of this study suggest that the sustained elevation of serum bilirubin concentration within the physiological range can effectively retard the progression of Diabetic Kidney Disease (DKD). Furthermore, the hormonal attributes of bilirubin may underlie its renoprotective effects.

Claves:diabetic kidney disease, eGFR slope, hormonal mechanisms, physiological range, serum total bilirubin

Cita:Front Endocrinol (Lausanne) 2024; 15 : 1361840.

Autor/es:Cao, Can (a)
Wei, Shuwu (b)

institución:(a) Department of Nephrology and Endocrinology, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, China.
(b) Department of Nephrology and Endocrinology, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, China.

Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3389/fendo.2024.1361840

Acta dermato-venereologica
Selección SIIC: 23 Mayo, 2024
Acta dermato-venereologica

Risk of Head and Neck Cancer in Patients with Psoriasis: A Nationwide Population-based Study.

Risk of Head and Neck Cancer in Patients with Psoriasis: A Nationwide Population-based Study.

Fuente:Acta Dermato-venereologica

Extracto: Our study provides insights into the potential risks of head and neck cancer in patients with psoriasis, which could aid in refining patient management strategies.

Cita:Acta Derm Venereol 2024 May 17; 104 : adv18487.

Autor/es:Huh, Gene (a)
Kim, Dongjun (b)

institución:(a) Department of Otolaryngology head and neck surgery, St. Vincent's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
(b) Department of Otolaryngology head and neck surgery, St. Vincent's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suecia

Sitio web:http://dx.doi.org/10.2340/actadv.v104.18487

International wound journal
Selección SIIC: 23 Mayo, 2024
International wound journal

Foot self-care behaviour in primary care patients with diabetic foot ulcers: Structural equation modelling of psychological predictors.

Foot self-care behaviour in primary care patients with diabetic foot ulcers: Structural equation modelling of psychological predictors.

Fuente:International Wound Journal

Extracto: These findings suggest illness perceptions, diabetes distress, and self-care confidence as modifiable predictors to be targeted in self-management interventions for patients with DFUs.

Claves:diabetes distress, diabetic foot ulcer, foot care confidence, foot self‐care behaviour, illness perception

Cita:Int Wound J 2024 May; 21 (5) : e14897.

Autor/es:Zhu, Xiaoli (a)
Lee, Eng Sing (b)

institución:(a) National Healthcare Group Polyclinics, Singapore, Singapore.
(b) Population/Global Health, Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.

Conflicto:The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Formato:Informe impreso

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1111/iwj.14897

Molecular medicine reports
Selección SIIC: 23 Mayo, 2024
Molecular medicine reports

LncRNA microarray profiling identifies novel circulating lncRNAs in hidradenitis suppurativa.

LncRNA microarray profiling identifies novel circulating lncRNAs in hidradenitis suppurativa.

Fuente:Molecular Medicine Reports

Extracto: In conclusion, the three lncRNAs isolated in the present study may be useful for improving the prognostic prediction of HS, as well as contributing towards an improved understanding of the underlying pathogenic mechanisms, thereby potentially providing new therapeutic targets.

Claves:RT‑qPCR, gene regulation, hidradenitis suppurativa, long noncoding RNAs, microRNAs

Cita:Mol Med Rep 2024 Jul; 30 (1)

Autor/es:De Felice, Bruna (a)
De Luca, Pasquale (b)

institución:(a) Department of Environmental, Biological and Pharmaceutical Sciences and Technologies, University of Campania Luigi Vanvitelli, I-81100 Caserta, Italy.
(b) Anton Dohrn Naples Zoological Station, I-80121 Naples, Italy.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe impreso

Idioma:Inglés

País de fuente:Grecia

Sitio web:http://dx.doi.org/10.3892/mmr.2024.13236

CNS neuroscience & therapeutics
Selección SIIC: 23 Mayo, 2024
CNS neuroscience & therapeutics

The causal relationship between sarcopenia-related traits and ischemic stroke: Insights from univariable and multivariable Mendelian randomization analyses.

The causal relationship between sarcopenia-related traits and ischemic stroke: Insights from univariable and multivariable Mendelian randomization analyses.

Fuente:Cns Neuroscience & Therapeutics

Extracto: Our study revealed a causal protective effect of higher ALM on IS, independent of physical activity and adiposity-related indices. Moreover, we found that higher ALM could reduce susceptibility to IS partially by lowering the risk of vascular risk factors, including CHD, hypertension, T2DM, and hyperlipidemia. In brief, we elucidated another modifiable factor for IS and implied that maintaining sufficient muscle mass may reduce the risk of such disease.

Claves:Mendelian randomization, appendicular lean mass, ischemic stroke, mediators, sarcopenia

Cita:CNS Neurosci Ther 2024 May; 30 (5) : e14759.

Autor/es:Song, Jiahao (a)
Zhou, Da (b)

institución:(a) Department of Neurology, Xuanwu Hospital, Capital Medical University, Beijing, China.
(b) Advanced Center of Stroke, Beijing Institute for Brain Disorders, Beijing, China.

Conflicto:It is noteworthy that this study only used publicly available summary‐level GWAS data and did not involve the utilization of individual‐level statistics, thus no ethical approval was required. No potential conflict of interest was reported by the authors.

Formato:Informe impreso

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1111/cns.14759

Journal of global health
Selección SIIC: 23 Mayo, 2024
Journal of global health

Multimodal data integration for enhanced longitudinal prediction for cardiac and cerebrovascular events following initial diagnosis of obstructive sleep apnea syndrome.

Multimodal data integration for enhanced longitudinal prediction for cardiac and cerebrovascular events following initial diagnosis of obstructive sleep apnea syndrome.

Fuente:Journal of Global Health

Tipo de trabajo:Revisión

Extracto: Our findings demonstrated the construction of an innovative visualisation tool that utilises various types of data to predict poor outcomes in Chinese patients diagnosed with OSAS, providing accurate and personalised therapy. REGISTRATION: Chinese Clinical Trial Registry ChiCTR2300075727.

Cita:J Glob Health 2024 May 17; 14 : 04103.

Autor/es:Zhou, Tong (a)
Wang, Yijun (b)

institución:(a) Department of Cardiology, First Affiliated Hospital of Bengbu Medical University, Bengbu, China.
(b) Department of Cardiology, Renmin Hospital of Wuhan University, Wuhan, China.

Conflicto:Disclosure of interest: The authors completed the ICMJE Disclosure of Interest Form (available upon request from the corresponding author) and disclose no relevant interests.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Scotland

Sitio web:http://dx.doi.org/10.7189/jgh.14.04103

Clinical and experimental medicine
Selección SIIC: 23 Mayo, 2024
Clinical and experimental medicine

Cardioprotective effects of vaccination in hospitalized patients with COVID-19.

Cardioprotective effects of vaccination in hospitalized patients with COVID-19.

Fuente:Clinical and Experimental Medicine

Extracto: Our findings suggest that COVID-19 vaccination may confer both direct and indirect cardioprotective effects in hospitalized COVID-19 patients.

Claves:Acute cardiac events, Biomarker, COVID-19 disease, Cardiotropism, Troponin, Vaccination

Cita:Clin Exp Med 2024 May 17; 24 (1) : 103.

Autor/es:Madrid, Julian (a)
Agarwal, Prerana (b)

institución:(a) Department of Cardiology, Pneumology, Angiology, Acute Geriatrics and Intensive Care, Ortenau Klinikum, Klostenstraße 19, 77933, Lahr/Schwarzwald, Germany. julian.madrid@ortenau-klinikum.de.
(b) Department of Diagnostic and Interventional Radiology, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Hugstetter Str. 55, 79106, Freiburg, Germany.

Conflicto:The authors have no relevant financial or non-financial interests to disclose.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Italia

Sitio web:http://dx.doi.org/10.1007/s10238-024-01367-3

PloS one
Selección SIIC: 23 Mayo, 2024
PloS one

Effect modification of diabetic status on the association between exposure to particulate matter and cardiac arrhythmias in a general population

Effect modification of diabetic status on the association between exposure to particulate matter and cardiac arrhythmias in a general population

Fuente:Plos One

Tipo de trabajo:Revisión sistemática

Extracto: Further studies with larger sample sizes and low bias are needed.

Cita:PLoS One 2024; 19 (5) : e0301766.

Autor/es:Tassanaviroj, Kiattichat (a)
Plodpai, Pimchanok (b)

institución:(a) Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.
(b) Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1371/journal.pone.0301766

Selección SIIC: 23 Mayo, 2024

Effectiveness of the ALT/AST ratio for predicting insulin resistance in a Korean population

Effectiveness of the ALT/AST ratio for predicting insulin resistance in a Korean population

Fuente:Plos One

Tipo de trabajo:Estudio de cohortes

Extracto: A simple, precise marker that represents the ALT/AST ratio could be a practical method to screen for insulin resistance in the general population, regardless of diabetes mellitus, alcohol intake, and sex.

Cita:PLoS One 2024; 19 (5) : e0303333.

Autor/es:Han, Seul Ki (a)
Seo, Myung Jae (b)

institución:(a) Division of Gastroenterology and Hepatology, Department of Internal Medicine, Yonsei University Wonju College of Medicine, Wonju, Korea.
(b) Regeneration Medicine Research Center, Yonsei University Wonju College of Medicine, Wonju, Korea.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1371/journal.pone.0303333

Selección SIIC: 23 Mayo, 2024

Bacteriological analysis and antibiotic resistance in patients with diabetic foot ulcers in Dhaka.

Bacteriological analysis and antibiotic resistance in patients with diabetic foot ulcers in Dhaka.

Fuente:Plos One

Extracto: On the other hand, gram-positive Staphylococcus aureus mostly showed sensitivity towards vancomycin and norfloxacin (79.17%).

Cita:PLoS One 2024; 19 (5) : e0301767.

Autor/es:Baral, Poulomi (a)
Afnan, Nafisa (b)

institución:(a) Microbiology Program, Department of Mathematics and Natural Sciences, BRAC University, Dhaka, Bangladesh.
(b) Microbiology Program, Department of Mathematics and Natural Sciences, BRAC University, Dhaka, Bangladesh.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1371/journal.pone.0301767

Selección SIIC: 23 Mayo, 2024

The effect of calcaneus and metatarsal head offloading insoles on healthy subjects' gait kinematics, kinetics, asymmetry, and the implications for plantar pressure management: A pilot study.

The effect of calcaneus and metatarsal head offloading insoles on healthy subjects' gait kinematics, kinetics, asymmetry, and the implications for plantar pressure management: A pilot study.

Fuente:Plos One

Extracto: The study found that offloading insoles reduced plantar pressure in the region of interest with loading transferred to surrounding regions increasing the risk of higher pressure time integrals in these locations. Heel strike and toe-off velocities were increased under certain configurations of offloading insoles which may explain the higher plantar pressures and supporting the potential of integrating kinematic gait variables within a more optimal therapeutic approach. However, there was inter-individual variability in responses for all variables measured supporting individualised prescription.

Cita:PLoS One 2024; 19 (5) : e0303826.

Autor/es:Shuang, Jiawei (a)
Haron, Athia (b)

institución:(a) School of Engineering, University of Manchester, Manchester, United Kingdom.
(b) School of Engineering, University of Manchester, Manchester, United Kingdom.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1371/journal.pone.0303826

BMJ open
Selección SIIC: 23 Mayo, 2024
BMJ open

Effect of metformin use on graft and patient survival in kidney transplant recipients with type 2 diabetes

Effect of metformin use on graft and patient survival in kidney transplant recipients with type 2 diabetes

Fuente:Bmj Open

Tipo de trabajo:Revisión sistemática

Extracto: PROSPERO REGISTRATION NUMBER: CRD42023421799.

Claves:Adult nephrology, Diabetic nephropathy & vascular disease, Renal transplantation

Cita:BMJ Open 2024 May 16; 14 (5) : e078393.

Autor/es:Shamshad, Farooq (a)
Tungsanga, Somkanya (b)

institución:(a) Division of Nephrology and Immunology, University of Alberta Faculty of Medicine & Dentistry, Edmonton, Alberta, Canada shamshad@ualberta.ca.
(b) Division of Nephrology and Immunology, University of Alberta Faculty of Medicine & Dentistry, Edmonton, Alberta, Canada.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1136/bmjopen-2023-078393

Selección SIIC: 23 Mayo, 2024

Preferred sources of information on diabetes prevention programmes: a population-based cross-sectional study in Poland.

Preferred sources of information on diabetes prevention programmes: a population-based cross-sectional study in Poland.

Fuente:Bmj Open

Extracto: Communication on DM2 prevention should be adjusted to public preferences and expectations. Tailoring interventions to different demographic groups can enhance outreach and engagement. Email emerged as a popular choice, suggesting the potential of digital communication in preventive health programmes.

Claves:diabetes & endocrinology, health education, preventive medicine

Cita:BMJ Open 2024 May 17; 14 (5) : e083362.

Autor/es:Grudziąż-Sękowska, Justyna (a)
Sękowski, Kuba (b)

institución:(a) School of Public Health, Centrum Medyczne Ksztalcenia Podyplomowego, Warsaw, Poland jgrudziaz@cmkp.edu.pl.
(b) School of Public Health, Centrum Medyczne Ksztalcenia Podyplomowego, Warsaw, Poland.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1136/bmjopen-2023-083362

Selección SIIC: 23 Mayo, 2024

Association between hypertensive disorders and Bell's palsy in pregnancy

Association between hypertensive disorders and Bell's palsy in pregnancy

Fuente:Bmj Open

Tipo de trabajo:Revisión sistemática

Extracto: PROSPERO REGISTRATION NUMBER: CRD42023422902.

Claves:Hypertension, Neurology, Prenatal diagnosis

Cita:BMJ Open 2024 May 17; 14 (5) : e080322.

Autor/es:Liu, Ya-Na (a)
Yang, Lin-Yi (b)

institución:(a) Department of Obstetrics and Gynecology, West China Second University Hospital, Sichuan University, Chengdu, China.
(b) Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education, Chengdu, China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1136/bmjopen-2023-080322

Selección SIIC: 23 Mayo, 2024

Feasibility and acceptability of a tailored health coaching intervention to improve type 2 diabetes self-management in Saudi Arabia: a mixed-methods randomised feasibility trial.

Feasibility and acceptability of a tailored health coaching intervention to improve type 2 diabetes self-management in Saudi Arabia: a mixed-methods randomised feasibility trial.

Fuente:Bmj Open

Tipo de trabajo:Estudio aleatorizado y controlado

Extracto: The findings demonstrated positive outcomes, supporting the need for a larger randomised controlled trial to evaluate the efficacy of health coaching in improving diabetes self-management among individuals with type 2 diabetes in Saudi Arabia.

Claves:Behavior, DIABETES & ENDOCRINOLOGY, PUBLIC HEALTH

Cita:BMJ Open 2024 May 17; 14 (5) : e078631.

Autor/es:Almulhim, Abdullah N (a)
Alhowaish, Atheer (b)

institución:(a) School of Medicine and Population Health, The University of Sheffield, Sheffield, UK aalmulhim@seu.edu.sa.
(b) Public Health Department, College of Health Sciences, Saudi Electronic University, Riyadh, 13316, Saudi Arabia.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1136/bmjopen-2023-078631

Scientific reports
Selección SIIC: 23 Mayo, 2024
Scientific reports

Development of a nomogram for identifying periodontitis cases in Denmark.

Development of a nomogram for identifying periodontitis cases in Denmark.

Fuente:Scientific Reports

Extracto: Hence, our nomograms could help identify periodontitis among adults in Denmark.

Cita:Sci Rep 2024 May 17; 14 (1) : 11280.

Autor/es:Cassiano, Luisa Schertel (a)
Jensen, Anne B (b)

institución:(a) Section for Oral Ecology, Department of Dentistry and Oral Health, Aarhus University, Vennelyst Boulevard 9, 8000, Aarhus, Denmark. lscassiano@dent.au.dk.
(b) Section for Oral Ecology, Department of Dentistry and Oral Health, Aarhus University, Vennelyst Boulevard 9, 8000, Aarhus, Denmark.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1038/s41598-024-60624-3

Selección SIIC: 23 Mayo, 2024

Mortality outcomes in diabetic metabolic dysfunction-associated fatty liver disease: non-obese versus obese individuals.

Mortality outcomes in diabetic metabolic dysfunction-associated fatty liver disease: non-obese versus obese individuals.

Fuente:Scientific Reports

Extracto: Patients with concurrent T2DM and MAFLD should be screened, regardless of the presence of obesity.

Claves:Metabolic (dysfunction)-associated fatty liver disease, Mortality, Normal weight, Obesity, Type 2 diabetes mellitus

Cita:Sci Rep 2024 May 17; 14 (1) : 11320.

Autor/es:Zhang, Pengwei (a)
Zeng, Yijun (b)

institución:(a) Affiliated Hospital of Hangzhou Normal University, Hangzhou Normal University, Hangzhou, 310015, China.
(b) Hangzhou Normal University, Hangzhou, 310015, China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1038/s41598-024-61896-5

Selección SIIC: 23 Mayo, 2024

Dietary intake, obesity, and metabolic risk factors among children and adolescents in the SEACO-CH20 cross-sectional study.

Dietary intake, obesity, and metabolic risk factors among children and adolescents in the SEACO-CH20 cross-sectional study.

Fuente:Scientific Reports

Extracto: These findings emphasise the necessity of longitudinal studies to explore the complex relationship between diet and long-term health outcomes, including cardiometabolic diseases, while acknowledging the unique challenges posed by the COVID-19 pandemic on data collection and analysis.

Cita:Sci Rep 2024 May 17; 14 (1) : 11265.

Autor/es:Ramadas, Amutha (a)
Rizal, Hussein (b)

institución:(a) Jeffrey Cheah School of Medicine and Health Sciences, Monash University Malaysia, 47500, Bandar Sunway, Malaysia. amutha.ramadas@monash.edu.
(b) Jeffrey Cheah School of Medicine and Health Sciences, Monash University Malaysia, 47500, Bandar Sunway, Malaysia.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1038/s41598-024-61090-7

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