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Autor/es:Jabbar Al-Rikabi, Saad Ayyal (a) Etemadi, Ali (b)
institución:(a) Department of Clinical Biochemistry, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran. (b) Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
The prevention of adverse pregnancy outcomes by periodontal treatment during pregnancy (PROBE) intervention study-A controlled intervention study: Protocol paper.
The prevention of adverse pregnancy outcomes by periodontal treatment during pregnancy (PROBE) intervention study-A controlled intervention study: Protocol paper.
Fuente:Plos One
Tipo de trabajo:Revisión
Extracto:
CLINICAL TRIALS REGISTRATION: The study was registered on
clinicaltrials.gov (NCT06110143).
institución:(a) The Research Unit for Dietary Studies, The Parker Institute, Copenhagen University Hospital, Copenhagen, Denmark. (b) The Research Unit for Dietary Studies, The Parker Institute, Copenhagen University Hospital, Copenhagen, Denmark.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Cost-effectiveness of a complex continuum of care intervention targeting women and children: protocol for an economic evaluation of the Bukhali trial in South Africa.
Cost-effectiveness of a complex continuum of care intervention targeting women and children: protocol for an economic evaluation of the Bukhali trial in South Africa.
Claves:community child health, diabetes in pregnancy, economics, health economics, obesity, postpartum period
Cita:BMJ Open 2024 May 13; 14 (5) : e080166.
Autor/es:Palmer, Tom (a) Leiva Granados, Rolando (b)
institución:(a) Institute for Global Health, University College London, London, UK t.palmer@ucl.ac.uk. (b) Institute for Global Health, University College London, London, UK.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Extracto:
They will give healthcare providers a better awareness of the optimal
analgesic medication for pain treatment in non-severe, acute pancreatitis.
Autor/es:Subramani, Sriya S (a) Berg, Alaina C (b)
institución:(a) Stead Family Department of Pediatrics, The University of Iowa, Roy J and Lucille A Carver College of Medicine, Iowa City, Iowa, USA. (b) The University of Iowa, Roy J and Lucille A Carver College of Medicine, Iowa City, Iowa, USA.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
The pan-PPAR agonist lanifibranor improves cardiometabolic health in patients with metabolic dysfunction-associated steatohepatitis.
The pan-PPAR agonist lanifibranor improves cardiometabolic health in patients with metabolic dysfunction-associated steatohepatitis.
Fuente:Nature Communications
Extracto:
Here, we show that effects of lanifibranor on liver
histology in MASH are accompanied with CMH improvement, indicative of potential
cardiovascular clinical benefits.
Cita:Nat Commun 2024 May 10; 15 (1) : 3962.
Autor/es:Cooreman, Michael P (a) Butler, Javed (b)
institución:(a) Research and Development, Inventiva, New York, NY, USA. Michael.Cooreman@inventivapharma.com. (b) Research and Development, Inventiva, Daix, France. Michael.Cooreman@inventivapharma.com.
Conflicto:M.P.C., L.D., P.H.M., M.B. and P.B. are employees of Inventiva. J.L.J. is a consultant for Inventiva. D.R.B. has received honoraria from Inventiva via Translational Medicine Academy. J.B. has served as a consultant for Abbott, American Regent, Amgen, Applied Therapeutic, AskBio, Astellas, AstraZeneca, Bayer, Boehringer Ingelheim, Boston Scientific, Bristol Myers Squibb, Cardiac Dimension, Cardiocell, Cardior, Cardiorem, CSL Bearing, CVRx, Cytokinetics, Daxor,...
Edwards, Element Science, Faraday, Foundry, G3P, Innolife, Impulse Dynamics, Imbria, Inventiva, Ionis, Lexicon, Lilly, LivaNova, Janssen, Medtronics, Merck, Occlutech, Owkin, Novartis, Novo Nordisk, Pfizer, Pharmacosmos, Pharmain, Prolaio, Regeneron, Renibus, Roche, Salamandra, Sanofi, SC Pharma, Secretome, Sequana, SQ Innovation, Tenex, Tricog, Ultromics, Vifor, and Zoll. RPG received research support or honoraria form Amgen, Anthos Therapeutics, Daiichi Sankyo, Ionis, Dr. Reddy’s Laboratories, Medical Education Resources, Menarini, SAJA Pharmaceuticals, Servier, SUMMEET, and consults for Artivion, Beckman Coulter, Daiichi Sankyo, Gilead, Inari, Inventiva, PhaseBio Pharmaceuticals, Samsung and Aventis. FZ reports personal fees from 89Bio, Abbott, Acceleron, Applied Therapeutics, Bayer, Betagenon, Boehringer, BMS, CVRx, Cambrian, Cardior, Cereno pharmaceutical, Cellprothera, CEVA, Inventiva, KBP, Merck, NovoNordisk, Owkin, Otsuka, Roche Diagnostics, Northsea, USa2, having stock options at G3Pharmaceutical and equities at Cereno, Cardiorenal, Eshmoun Clinical research and being the founder of Cardiovascular Clinical Trialists. MFA received grants from Boehringer-Ingelheim, Gilead, Hanmi, Inventiva, Madrigal, Novo Nordisk; honoraria from Clinical Care Options, Fishawack, Medscape, Terra Firma, CLDF; royalties from Up-to-Date; consults for 89Bio, BMS, Hanmi, Inventiva, Intercept, Madrigal, Merck, Novo Nordisk. SMF received grants from Astellas, Falk Pharma, Genfit, Gilead Sciences, GlympsBio, Janssens Pharmaceutica, Inventiva, Merck Sharp & Dome, Pfizer, Roche; honoraria from Abbvie, Allergan, Bayer, Eisai, Genfit, Gilead Sciences, Janssens Cilag, Intercept, Inventiva, Merck Sharp & Dome, Novo Nordisk, Promethera, Siemens; serves as consultant for Abbvie, Actelion, Aelin Therapeutics, AgomAb, Aligos Therapeutics, Allergan, Alnylam, Astellas, Astra Zeneca, Bayer, Boehringer Ingelheim, Bristoll-Meyers Squibb, CSL Behring, Coherus, Echosens, Dr. Falk Pharma, Eisai, Enyo, Galapagos, Galmed, Genetech, Genfit, Genflow Biosciences, Gilead Sciences, Intercept, Inventiva, Janssens Pharmaceutica, PRO.MED.CS Praha, Julius Clinical, Madrigal, Medimmune, Merck Sharp & Dome, Mursla Bio, NGM Bio, Novartis, Novo Nordisk, Promethera, Roche, Siemens Healthineers.
Lipids as potential mediators linking body mass index to diabetes: evidence from a mediation analysis based on the NAGALA cohort.
Lipids as potential mediators linking body mass index to diabetes: evidence from a mediation analysis based on the NAGALA cohort.
Fuente:Bmc Endocrine Disorders
Extracto:
Our fresh findings
suggested that lipid parameters partially mediated the association of BMI with
diabetes risk; this result indicated that in the context of diabetes risk
screening and disease management, it is important to not only monitor BMI but
also pay attention to lipid parameters, particularly HDL-C and HDL-C-related
lipid ratio parameters.
Claves:Body mass index, Diabetes, Indirect effect, Lipid parameters, Mediation analyses
Cita:BMC Endocr Disord 2024 May 10; 24 (1) : 66.
Autor/es:Lu, Song (a) Wang, Qun (b)
institución:(a) Department of Cardiology, The First Affiliated Hospital of Nanchang University, Jiangxi Medical College, Nanchang University, Nanchang, 330006, China. (b) Jiangxi Cardiovascular Research Institute, Jiangxi Provincial People's Hospital, The First Affiliated Hospital of Nanchang Medical College, Nanchang, 330006, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
institución:(a) Affiliated Hospital of Huanghuai University, Zhumadian Central Hospital, Zhumadian, 463000, He'nan, People's Republic of China. renyongcheng@huanghuai.edu.cn. (b) Institute of Health Data Management, Huanghuai University, Zhumadian, 463000, He'nan, People's Republic of China. renyongcheng@huanghuai.edu.cn.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Potential impact of blood cholesterol guidelines on statin treatment in the U.S. population using interrupted time series analysis.
Potential impact of blood cholesterol guidelines on statin treatment in the U.S. population using interrupted time series analysis.
Fuente:Bmc Cardiovascular Disorders
Tipo de trabajo:Guía
Extracto:
The 2013 ACA/AHA Guideline release is associated with trend
improvements in the long-term MACE Survival for Diabetes group and optimal statin
use for ASCVD group. These significant associations might indicate a potential
positive long-term impact of the 2013 ACA/AHA Guideline on better health outcomes
for primary prevention groups and an immediate potential impact on statin
prescribing behaviors in higher-at-risk groups. However, further investigation is
required to confirm the causal effect of the 2013 ACA/AHA Guideline.
Claves:Cardiovascular disease, Diabetes, Generic atorvastatin, Guideline implementation, Interrupted time series analysis, Long-term effect, MACE, Policy effect
Cita:BMC Cardiovasc Disord 2024 May 10; 24 (1) : 245.
Autor/es:Yew, Pui Ying (a) Loth, Matt (b)
institución:(a) Institute for Health Informatics, University of Minnesota, Minneapolis, MN, USA. (b) Institute for Health Informatics, University of Minnesota, Minneapolis, MN, USA.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Association of RASGRP1 polymorphism with vascular complications in Chinese diabetic patients with glycemic control and antihypertensive treatment.
Association of RASGRP1 polymorphism with vascular complications in Chinese diabetic patients with glycemic control and antihypertensive treatment.
Fuente:Cardiovascular Diabetology
Extracto:
We found that
patients with G allele of RASGRP1 (rs56254815) showed a better antihypertensive
therapy efficacy in T2DM patients. The rs7403531 T allele could reduce the risk
of major microvascular events and major eye diseases in T2DM patients receiving
either hypoglycemic or antihypertensive therapy. Our findings suggest that
RASGRP1 genetic polymorphism might predict the cardiovascular complications in
T2DM patients.
Claves:Individual drug treatment, Polymorphism, RASGRP1, Type 2 diabetes, Vascular complications, rs7403531
Cita:Cardiovasc Diabetol 2024 May 10; 23 (1) : 166.
Autor/es:Zhou, Jiecan (a) Xu, Bo (b)
institución:(a) The First Affiliated Hospital, Hunan Provincial Clinical Medical Research Center for Drug Evaluation of Major Chronic Diseases, Hengyang Medical School, University of South China, 421001, Hengyang, Hunan, China. zhoujiecan@fsyy.usc.edu.cn. (b) The First Affiliated Hospital, Hengyang Clinical Pharmacology Research Center, Hengyang Medical School, University of South China, 421001, Hengyang, Hunan, China. zhoujiecan@fsyy.usc.edu.cn.
Conflicto:All authors declare no conflict of interest relevant to the subject matter or materials discussed in the article.
Prognostic value of metabolic dysfunction-associated steatotic liver disease over coronary computed tomography angiography findings: comparison with no-alcoholic fatty liver disease.
Prognostic value of metabolic dysfunction-associated steatotic liver disease over coronary computed tomography angiography findings: comparison with no-alcoholic fatty liver disease.
Fuente:Cardiovascular Diabetology
Extracto:
Patients with MASLD are
likely to have a higher risk of cardiovascular disease than those with NAFLD.
Concurrent assessment of MASLD during CCTA improves the identification of
patients at a higher risk of cardiovascular disease among those with clinically
indicated CCTA.
Contributions of elevated CRP, hyperglycaemia, and type 2 diabetes to cardiovascular risk in the general population: observational and Mendelian randomization studies.
Contributions of elevated CRP, hyperglycaemia, and type 2 diabetes to cardiovascular risk in the general population: observational and Mendelian randomization studies.
Fuente:Cardiovascular Diabetology
Extracto:
Elevated concentrations of
plasma CRP and glucose are predictors of IHD and CVD death in the general
population. We found no genetic association between CRP and glucose, or vice
versa, suggesting that lowering glucose pharmacologically does not have a direct
effect on low-grade inflammation.
Cita:Cardiovasc Diabetol 2024 May 10; 23 (1) : 165.
Autor/es:Rolver, Monica G (a) Emanuelsson, Frida (b)
institución:(a) Department of Clinical Biochemistry, Copenhagen University Hospital - Herlev Gentofte, Borgmester Ib Juuls Vej 1, Herlev, 2730, Denmark. (b) Institute of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3B, Copenhagen, 2200, Denmark.
Conflicto:Monica Gylling Rolver is part-time employed by Novo Nordisk Denmark as a student assistant. Other authors report no conflict of interest related to the present study.
Association of neutrophil-lymphocyte ratio with all-cause and cardiovascular mortality in US adults with diabetes and prediabetes
Association of neutrophil-lymphocyte ratio with all-cause and cardiovascular mortality in US adults with diabetes and prediabetes
Fuente:Bmc Endocrine Disorders
Tipo de trabajo:Estudio de cohortes
Extracto:
The findings of this
prospective cohort study conducted in the US indicate a positive association of
elevated NLR levels with heightened risks of overall and cardiovascular mortality
among adults with diabetes and prediabetes. However, potential confounding
factors for NLR and the challenge of monitoring NLR's fluctuations over time
should be further focused.
institución:(a) Department of Endocrinology and Metabolism, Guangzhou Red Cross Hospital, Jinan University, Guangzhou, 510220, Guangdong, China. (b) State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510120, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Low ankle-brachial index is associated with higher cardiovascular mortality in individuals with nonalcoholic fatty liver disease.
Low ankle-brachial index is associated with higher cardiovascular mortality in individuals with nonalcoholic fatty liver disease.
Fuente:European Journal of Medical Research
Tipo de trabajo:Estudio de cohortes
Extracto:
Low ABI is independently
associated with higher cardiovascular mortality in NAFLD cases. This correlation
remains significant even in the absence of pre-existing cardiovascular disease or
diabetes.
institución:(a) Department of Geriatric Endocrinology and Metabolism, The First Affiliated Hospital of Guangxi Medical University, No. 6 Shuangyong Road, Nanning, 530021, Guangxi, China. (b) Department of Geriatric Endocrinology and Metabolism, The First Affiliated Hospital of Guangxi Medical University, No. 6 Shuangyong Road, Nanning, 530021, Guangxi, China.
Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
A Cross-Sectional Study of Glomerular Hyperfiltration in Polycystic Ovary Syndrome.
A Cross-Sectional Study of Glomerular Hyperfiltration in Polycystic Ovary Syndrome.
Fuente:International Journal of Molecular Sciences
Extracto:
There were
progressive eGFR decrements for PCOS-nonGH, PCOS-GH, and PCOS-SGH in the
follow-up period which, in the presence of additional factors affecting renal
function, may be clinically important in the development of CKD in PCOS.
Autor/es:Butler, Alexandra E (a) Lubbad, Walaa (b)
institución:(a) Research Department, Royal College of Surgeons in Ireland Bahrain, Busaiteen, Adliya P.O. Box 15503, Bahrain. (b) Research Department, Royal College of Surgeons in Ireland Bahrain, Busaiteen, Adliya P.O. Box 15503, Bahrain.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
JMJD6 Autoantibodies as a Potential Biomarker for Inflammation-Related Diseases.
JMJD6 Autoantibodies as a Potential Biomarker for Inflammation-Related Diseases.
Fuente:International Journal of Molecular Sciences
Extracto:
Hence, JMJD6 autoantibodies may
reflect inflammation, thereby serving as a potential biomarker for diagnosing
specific inflammation-related diseases, including stroke, AMI, DM, and cancers,
and for prediction of the prognosis in patients with EC.
institución:(a) Department of Neurological Surgery, Graduate School of Medicine, Chiba University, Chiba 260-8670, Japan. (b) Department of Biochemistry and Genetics, Graduate School of Medicine, Chiba University, Chiba 260-8670, Japan.
Conflicto:This present study was performed in collaboration with Fujikura Kasei Co., Ltd., and Hideyuki Kuroda is an employee of Fujikura Kasei Co., Ltd. The other authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
The Mediterranean Diet, Its Microbiome Connections, and Cardiovascular Health
The Mediterranean Diet, Its Microbiome Connections, and Cardiovascular Health
Fuente:International Journal of Molecular Sciences
Tipo de trabajo:Revisión
Extracto:
This review will
focus on the effects of MD on cardiovascular health through its action on gut
microbiota.
Claves:Mediterranean-type diet, Western-type diet, atherosclerosis, bile acids, cardiovascular disease, gut microbiota, nutrients, short-chain fatty acid, trimethylamine N-oxide
Cita:Int J Mol Sci 2024 Apr 30; 25 (9)
Autor/es:Abrignani, Vincenzo (a) Salvo, Andrea (b)
institución:(a) Internal Medicine and Stroke Care Ward, University of Palermo, 90127 Palermo, Italy. (b) Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties, University of Palermo, 90127 Palermo, Italy.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Pre-Pregnancy Obesity and Infants' Motor Development within the First Twelve Months of Life: Who Is Expected to Be the Ultimate Carrier of the Obesity Burden?
Pre-Pregnancy Obesity and Infants' Motor Development within the First Twelve Months of Life: Who Is Expected to Be the Ultimate Carrier of the Obesity Burden?
Fuente:Nutrients
Extracto:
Pre-pregnancy obesity is a critical
determinant of pregnancy outcomes and offspring early motor development, with
possible far-reaching implications for children's long-term well-being.
Addressing this issue requires a comprehensive approach that includes
preconception weight management, targeted interventions during the pregnancy and
postpartum periods, and ongoing research to better understand the underlying
mechanisms and develop effective strategies for prevention and management.
Claves:complications, early motor development, offspring, pre-pregnancy obesity
Cita:Nutrients 2024 Apr 24; 16 (9)
Autor/es:Lackovic, Milan (a) Nikolic, Dejan (b)
institución:(a) Department of Obstetrics and Gynecology, University Hospital "Dragisa Misovic", Heroja Milana Tepica 1, 11000 Belgrade, Serbia. (b) Faculty of Medicine, University of Belgrade, 11000 Belgrade, Serbia.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Validation of Nutritional Approaches to Modulate Cardiovascular and Diabetic Risk Factors in Patients with Hypertriglyceridemia or Prediabetes-The MoKaRi II Randomized Controlled Study.
Validation of Nutritional Approaches to Modulate Cardiovascular and Diabetic Risk Factors in Patients with Hypertriglyceridemia or Prediabetes-The MoKaRi II Randomized Controlled Study.
Fuente:Nutrients
Extracto:
In patients with elevated TG or fasting glucose,
implementing individualized menu plans in combination with regular counseling
sessions over 10 weeks led to a significant improvement in cardiovascular and
diabetic risk factors.
Claves:cardiovascular risk, diabetes mellitus type 2, fish oil supplementation, hypertriglyceridemia, menu plans, prediabetes
Cita:Nutrients 2024 Apr 24; 16 (9)
Autor/es:Braun, Theresa S (a) Drobner, Timo (b)
institución:(a) Junior Research Group Nutritional Concepts, Institute of Nutritional Sciences, Friedrich Schiller University Jena, Dornburger Straße 25-29, 07743 Jena, Germany. (b) Competence Cluster for Nutrition and Cardiovascular Health (nutriCARD) Halle-Jena-Leipzig, Dornburger Straße 25-29, 07743 Jena, Germany.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
The Role of Diet in the Cardiovascular Health of Childhood Cancer Survivors-A Systematic Review.
The Role of Diet in the Cardiovascular Health of Childhood Cancer Survivors-A Systematic Review.
Fuente:Nutrients
Tipo de trabajo:Revisión sistemática
Extracto:
The review results indicate the potentially
protective effects of healthy diets. However, the available research remains
preliminary and limited, underscoring the need for more rigorous, adequately
powered studies.
institución:(a) Children's Health & Exercise Research Centre (CHERC), Faculty of Health and Life Sciences, University of Exeter, Exeter EX1 2LU, UK. (b) Children's Health & Exercise Research Centre (CHERC), Faculty of Health and Life Sciences, University of Exeter, Exeter EX1 2LU, UK.
Conflicto:The authors report no conflict of interest.
Extracto:
This
consensus statement establishes a standardized approach to nutritional support,
aiming to optimize outcomes in pediatric cancer patients.
Claves:childhood cancer, nutrition, nutritional support
institución:(a) Department of Pediatrics, Pediatric Gastroenterology, Allergology and Nutrition, Medical University of Gdansk, 80-210 Gdansk, Poland. (b) Department of Pediatrics, Pediatric Gastroenterology, Allergology and Nutrition, Medical University of Gdansk, 80-210 Gdansk, Poland.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
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