Immunomodulation through Nutrition Should Be a Key Trend in Type 2 Diabetes Treatment.

Immunomodulation through Nutrition Should Be a Key Trend in Type 2 Diabetes Treatment.

Fuente:International Journal of Molecular Sciences

Extracto: The role of macronutrients, micronutrients, vitamins, and selected substances, such as omega-3 fatty acids, coenzyme Q10, and alpha-lipoic acid, was taken into consideration, which outlined the minimum range of tests that ought to be performed on patients in order to either directly or indirectly determine the severity of malnutrition in this group of patients.

Claves:alpha-lipoic acid, coenzyme Q10, immune system, immunomodulation, macroelements, microelements, nutrients, omega-3 acids, type 2 diabetes, vitamins

Cita:Int J Mol Sci 2024 Mar 28; 25 (7)

Autor/es:Napiórkowska-Baran, Katarzyna (a)
Treichel, Paweł (b)

institución:(a) Department of Allergology, Clinical Immunology and Internal Diseases, Collegium Medicum Bydgoszcz, Nicolaus Copernicus University Toruń, 85-067 Bydgoszcz, Poland.
(b) Student Research Club of Clinical Immunology, Department of Allergology, Clinical Immunology and Internal Diseases, Collegium Medicum Bydgoszcz, Nicolaus Copernicus University Toruń, 85-067 Bydgoszcz, Poland.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3390/ijms25073769

The Role of Endocrine Disruption Chemical-Regulated Aryl Hydrocarbon Receptor Activity in the Pathogenesis of Pancreatic Diseases and Cancer.

Fuente:International Journal of Molecular Sciences

Extracto: This review comprehensively examines the involvement of AHR in EDC exposure-mediated regulation of pancreatic pathogenesis, emphasizing AHR as a potential therapeutic target for the pathogenesis of pancreatic diseases and cancer.

Claves:aryl hydrocarbon receptor, endocrine disrupting chemicals, environmental toxicants, pancreas, pancreatic cancer, pancreatic injury, pancreatitis

Cita:Int J Mol Sci 2024 Mar 29; 25 (7)

Autor/es:aryl hydrocarbon receptor, endocrine disrupting chemicals, environmental toxicants, pancreas, pancreatic cancer, pancreatic injury, pancreatitis

institución:aryl hydrocarbon receptor, endocrine disrupting chemicals, environmental toxicants, pancreas, pancreatic cancer, pancreatic injury, pancreatitis

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3390/ijms25073818

Glucagon-like Peptide 1, Glucose-Dependent Insulinotropic Polypeptide, and Glucagon Receptor Agonists in Metabolic Dysfunction-Associated Steatotic Liver Disease: Novel Medication in New Liver Disease Nomenclature.

Fuente:International Journal of Molecular Sciences

Extracto: Finally, we discuss the current challenges and future perspectives pertinent to this growing area of research and clinical medicine.

Claves:glucagon receptor (GCGR), glucagon-like peptide-1 (GLP-1), glucose-dependent insulinotropic polypeptide (GIP), metabolic dysfunction-associated steatotic liver disease, type 2 diabetes mellitus

Cita:Int J Mol Sci 2024 Mar 29; 25 (7)

Autor/es:Chrysavgis, Lampros G (a)
Kazanas, Spyridon (b)

institución:(a) First Department of Internal Medicine, Medical School, National and Kapodistrian University of Athens, General Hospital Laiko, 115 27 Athens, Greece.
(b) First Department of Internal Medicine, Medical School, National and Kapodistrian University of Athens, General Hospital Laiko, 115 27 Athens, Greece.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3390/ijms25073832

Gestational Diabetes Mellitus and Colostral Appetite-Regulating Adipokines.

Fuente:International Journal of Molecular Sciences

Extracto: The shift between ghrelin and other appetite-regulating hormones might translate into altered ability to regulate energy balance, affecting offspring's metabolic homeostasis.

Claves:adipokines, gestational diabetes mellitus, human milk, lifestyle diseases

Cita:Int J Mol Sci 2024 Mar 29; 25 (7)

Autor/es:Lis-Kuberka, Jolanta (a)
Berghausen-Mazur, Marta (b)

institución:(a) Division of Chemistry and Immunochemistry, Department of Biochemistry and Immunochemistry, Wroclaw Medical University, M. Skłodowskiej-Curie 48/50, 50-369 Wroclaw, Poland.
(b) Department of Neonatology, J. Gromkowski Provincial Specialist Hospital, Koszarowa 5, 51-149 Wroclaw, Poland.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3390/ijms25073853

Association between PD-L1 Expression and the Prognosis and Clinicopathologic Features of Non-Clear Cell Renal Cell Carcinoma.

Fuente:International Journal of Molecular Sciences

Extracto: However, no differences in overall survival for PD-L1-positive pRCC patients with compared to PD-L1-negative patients were observed in tumor cells or TIMCs.

Claves:PD-L1, chromophobe renal cell carcinoma, papillary renal cell carcinoma, renal cell carcinoma

Cita:Int J Mol Sci 2024 Mar 31; 25 (7)

Autor/es:Chrabańska, Magdalena (a)
Szweda-Gandor, Nikola (b)

institución:(a) Department of Pathomorphology, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, 40-055 Katowice, Poland.
(b) Department and Clinic of Internal Medicine, Diabetology and Nephrology, Medical University of Silesia, 40-055 Zabrze, Poland.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3390/ijms25073916

Cell Death in Acute Organ Injury and Fibrosis.

Fuente:International Journal of Molecular Sciences

Extracto: issue fibrosis is characterized by the excessive accumulation of extracellular matrix in various organs, including the lungs, liver, skin, kidneys, pancreas, and heart, ultimately leading to organ failure [...].

Cita:Int J Mol Sci 2024 Apr 1; 25 (7)

Autor/es:Yasuma, Taro (a)
Gabazza, Esteban C (b)

institución:(a) Department of Immunology, Mie University Faculty and Graduate School of Medicine, Edobashi 2-174, Tsu 514-8507, Japan.
(b) Department of Diabetes and Endocrinology, Mie University Faculty and Graduate School of Medicine, Edobashi 2-174, Tsu 514-8507, Japan.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3390/ijms25073930

LDL Receptor-Related Protein 1B Polymorphisms Associated with Increased Risk of Lymph Node Metastasis in Oral Cancer Group with Diabetes Mellitus.

Fuente:International Journal of Molecular Sciences

Extracto: LRP1B genetic polymorphisms appear to be prognostic and diagnostic markers for OSCC and DM, as well as contributing to genetic profiling research for personalized medicine.

Claves:LRP1B, OSCC, diabetes mellitus

Cita:Int J Mol Sci 2024 Apr 2; 25 (7)

Autor/es:Chen, Liang-Cheng (a)
Lo, Yu-Sheng (b)

institución:(a) Division of Oral & Maxillofacial Surgery, Dental Department, Changhua Christian Hospital, Changhua 500, Taiwan.
(b) Oral Cancer Research Center, Changhua Christian Hospital, Changhua 500, Taiwan.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3390/ijms25073963

Molecular Targets of Novel Therapeutics for Diabetic Kidney Disease: A New Era of Nephroprotection.

Fuente:International Journal of Molecular Sciences

Extracto: In a new era of nephroprotection, these drugs, as pillars of personalized medicine, can improve renal outcomes and enhance the quality of life for individuals with DKD.

Claves:RAAS blockers, SGLT2 inhibitors, aldosterone synthase inhibitors, diabetic kidney disease, endothelin receptor antagonists, glucagon-like peptide-1 receptor agonists, mineralocorticoid receptor antagonists, pathogenetic mechanisms

Cita:Int J Mol Sci 2024 Apr 3; 25 (7)

Autor/es:Mazzieri, Alessio (a)
Porcellati, Francesca (b)

institución:(a) Diabetes Clinic, Department of Medicine and Surgery, University of Perugia, 06132 Perugia, Italy.
(b) Diabetes Clinic, Department of Medicine and Surgery, University of Perugia, 06132 Perugia, Italy.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3390/ijms25073969

TCF7L2 Polymorphism rs7903146 (C/T) and Gestational Diabetes Influence on Obstetric Outcome: A Romanian Case-Control Study.

Fuente:International Journal of Molecular Sciences

Extracto: The presence of at least one minor T allele was associated with a higher risk of fetal macrosomia.

Claves:TCF7L2 gene, fetal macrosomia, gestational diabetes mellitus, rs7903146 (C/T) polymorphism

Cita:Int J Mol Sci 2024 Apr 4; 25 (7)

Autor/es:Cruciat, Gheorghe (a)
Florian, Andreea Roxana (b)

institución:(a) Mother and Child Department, Obstetrics and Gynecology I, "Iuliu Haţieganu" University of Medicine and Pharmacy Cluj-Napoca, 400347 Cluj-Napoca, Romania.
(b) Mother and Child Department, Obstetrics and Gynecology I, "Iuliu Haţieganu" University of Medicine and Pharmacy Cluj-Napoca, 400347 Cluj-Napoca, Romania.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3390/ijms25074039

Mulberry Leaf Compounds and Gut Microbiota in Alzheimer's Disease and Diabetes: A Study Using Network Pharmacology, Molecular Dynamics Simulation, and Cellular Assays.

Fuente:International Journal of Molecular Sciences

Extracto: This research supports the concept of food-medicine homology and broadens the range of medical treatments for diabetes and AD, highlighting the prospect of integrating traditional herbal remedies with modern medical research.

Claves:Alzheimer’s disease, molecular dynamics simulation, mulberry leaf compounds, network pharmacology, type 2 diabetes mellitus

Cita:Int J Mol Sci 2024 Apr 5; 25 (7)

Autor/es:Bai, Xue (a)
Zhao, Xinyi (b)

institución:(a) Key Laboratory for Molecular Enzymology and Engineering of Ministry of Education, School of Life Sciences, Jilin University, Changchun 130012, China.
(b) Key Laboratory for Molecular Enzymology and Engineering of Ministry of Education, School of Life Sciences, Jilin University, Changchun 130012, China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3390/ijms25074062

The Importance of Intra-Islet Communication in the Function and Plasticity of the Islets of Langerhans during Health and Diabetes.

Fuente:International Journal of Molecular Sciences

Extracto: Resulting changes in paracrine dynamics within the islets can contribute to the emergence of Types 1, 2 and gestational diabetes.

Claves:beta-cell, gestational diabetes mellitus, islets of Langerhans, paracrine, plasticity, type 1 diabetes, type 2 diabetes

Cita:Int J Mol Sci 2024 Apr 6; 25 (7)

Autor/es:Hill, Thomas G (a)
Hill, David J (b)

institución:(a) Oxford Centre for Diabetes, Endocrinology, and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford OX3 9DU, UK.
(b) Lawson Health Research Institute, St. Joseph's Health Care, London, ON N6A 4V2, Canada.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3390/ijms25074070

Exploring the Pathophysiology of ATP-Dependent Potassium Channels in Insulin Resistance.

Fuente:International Journal of Molecular Sciences

Extracto: In this review, we aim to discuss the characteristics of KATP channels, their relationship with clinical disorders, and their mechanisms and potential associations with peripheral and central insulin resistance.

Claves:ATP-dependent potassium channels, insulin resistance, ionic channels

Cita:Int J Mol Sci 2024 Apr 6; 25 (7)

Autor/es:Rodríguez-Rivera, Nidia Samara (a)
Barrera-Oviedo, Diana (b)

institución:(a) Laboratorio de Farmacología y Bioquímica Clínica, Departamento de Farmacología, Facultad de Medicina, Universidad Nacional Autónoma de México, Mexico City 04510, Mexico.
(b) Laboratorio de Farmacología y Bioquímica Clínica, Departamento de Farmacología, Facultad de Medicina, Universidad Nacional Autónoma de México, Mexico City 04510, Mexico.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3390/ijms25074079

Metformin: A Dual-Role Player in Cancer Treatment and Prevention.

Fuente:International Journal of Molecular Sciences

Extracto: The aims of this review are to provide a contemporary understanding of the role of metformin in cancer therapy and identify areas for future exploration in the pursuit of effective anticancer strategies.

Claves:adjuvant therapy, anticancer, cancer, chemoresistance, clinical trials, mechanisms of action, metformin

Cita:Int J Mol Sci 2024 Apr 6; 25 (7)

Autor/es:Galal, Mariam Ahmed (a)
Al-Rimawi, Mohammed (b)

institución:(a) Department of Biochemistry and Molecular Medicine, College of Medicine, Alfaisal University, P.O. Box 50927, Riyadh 11533, Saudi Arabia.
(b) Department of Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol BS8 1QU, UK.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3390/ijms25074083

A Narrative Review on Adipose Tissue and Overtraining: Shedding Light on the Interplay among Adipokines, Exercise and Overtraining.

Fuente:International Journal of Molecular Sciences

Extracto: Furthermore, we will highlight adipokines as potential markers for diagnosing OTS.

Claves:adipokines, adipose tissue, athletes, exercise, lifestyle, overtraining syndrome, physical activity

Cita:Int J Mol Sci 2024 Apr 6; 25 (7)

Autor/es:Mallardo, Marta (a)
Daniele, Aurora (b)

institución:(a) Department of Molecular and Biotechnological Medicine, University of Naples "Federico II", 80131 Naples, Italy.
(b) CEINGE-Biotechnologies Advances S.c.a r.l., Via G. Salvatore 486, 80145 Naples, Italy.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3390/ijms25074089

Metabolic Health, Overweight or Obesity, and Depressive Symptoms among Older Australian Adults.

Metabolic Health, Overweight or Obesity, and Depressive Symptoms among Older Australian Adults.

Fuente:Nutrients

Extracto: The odds of experiencing moderate/severe depressive symptoms were increased in metabolically unhealthy older adults regardless of normal weight or obesity, with the odds of having moderate/severe depressive symptoms being higher in females than in males.

Claves:depression, depressive symptoms, metabolic health, normal weight, obesity, overweight

Cita:Nutrients 2024 Mar 23; 16 (7)

Autor/es:Opio, Jacob (a)
Wynne, Katie (b)

institución:(a) School of Medicine and Public Health, University of Newcastle, University Drive, Callaghan, NSW 2308, Australia.
(b) School of Medicine and Public Health, University of Newcastle, University Drive, Callaghan, NSW 2308, Australia.

Conflicto:No conflicts of interest are declared by the authors in relation to the research, authorship, and publication of this study. All authors declare that there was no support from, or financial relationship with, any organisation that might have an interest in the submitted work in the previous 36 months and that there are no other relationships or activities that could... appear to have influenced the submitted work.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3390/nu16070928

Development and Feasibility of an eHealth Diabetes Prevention Program Adapted for Older Adults-Results from a Randomized Control Pilot Study.

Fuente:Nutrients

Extracto: Standardized materials are provided for future implementation.

Claves:diet, eHealth, fitness, intervention, lifestyle medicine, older adults, remote monitoring, weight loss

Cita:Nutrients 2024 Mar 23; 16 (7)

Autor/es:Gerber, Suzannah (a)
Silver, Rachel E (b)

institución:(a) Gerald J. and Dorothy R. Friedman School of Nutrition Science and Policy, Tufts University, 150 Harrison Avenue, Boston, MA 02111, USA.
(b) Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, 711 Washington Street, Boston, MA 02111, USA.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3390/nu16070930

Inflammatory Dietary Potential Is Associated with Vitamin Depletion and Gut Microbial Dysbiosis in Early Pregnancy.

Fuente:Nutrients

Extracto: Dietary inflammatory potential was associated with a reduction in the consumption of vitamins and minerals and predicted gut microbiota metabolic dysregulation.

Claves:diet, dietary inflammatory index, food frequency questionnaire, galactose, gut microbiota, inflammation, pregnancy

Cita:Nutrients 2024 Mar 24; 16 (7)

Autor/es:Alvernaz, Suzanne A (a)
Wenzel, Elizabeth S (b)

institución:(a) Department of Biomedical Engineering, University of Illinois, Chicago, IL 60607, USA.
(b) Department of Psychology, University of Illinois, Chicago, IL 60607, USA.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3390/nu16070935

Association of Gut Microbiota-Related Metabolites and Type 2 Diabetes in Two Puerto Rican Cohorts.

Fuente:Nutrients

Tipo de trabajo:Metanálisis

Extracto: These observations demonstrate the importance of gut microbiota metabolites for human cardiometabolic health.

Claves:Puerto Rican, betaine, cardiometabolic risk factors, glycemia, gut microbiota metabolites, type 2 diabetes

Cita:Nutrients 2024 Mar 27; 16 (7)

Autor/es:Sawicki, Caleigh M (a)
Pacheco, Lorena S (b)

institución:(a) Channing Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, 181 Longwood Ave, Boston, MA 02115, USA.
(b) Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3390/nu16070959

Exploring Gene-Diet Interactions for Mother-Child Health

Fuente:Nutrients

Tipo de trabajo:Revisión sistemática

Extracto: Deeply understanding gene-diet interactions could be useful in developing highly personalized approaches to maternal and child nutrition, as well as in exploring the potential implications in disease prevention and the promotion of the long-term well-being of both mothers and their offspring.

Claves:diet, genetic variants, interaction, mother–child health, nutrition, pregnancy

Cita:Nutrients 2024 Mar 28; 16 (7)

Autor/es:Favara, Giuliana (a)
Maugeri, Andrea (b)

institución:(a) Department of Medical and Surgical Sciences and Advanced Technologies "GF Ingrassia", University of Catania, 95123 Catania, Italy.
(b) Department of Medical and Surgical Sciences and Advanced Technologies "GF Ingrassia", University of Catania, 95123 Catania, Italy.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3390/nu16070994

Visceral Adipose Tissue: The Hidden Culprit for Type 2 Diabetes.

Fuente:Nutrients

Extracto: Therefore, by reducing the amount of VAT accumulated in an individual and preventing it from building up, one can effectively control and prevent the development of T2D.

Claves:body composition, body mass index, free fatty acids, obesity, type 2 diabetes, visceral adipose tissue

Cita:Nutrients 2024 Mar 30; 16 (7)

Autor/es:Dhokte, Sneha (a)
Czaja, Krzysztof (b)

institución:(a) Department of Biomedical Sciences, College of Veterinary Medicine, University of Georgia, Athens, GA 30602, USA.
(b) Department of Biomedical Sciences, College of Veterinary Medicine, University of Georgia, Athens, GA 30602, USA.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3390/nu16071015