Feasibility of diagnosing osteoporosis using routine computed tomography scans for hip fractures: Correlation with histopathological diagnosis of head and neck regions.

Fuente:Acta Orthopaedica Et Traumatologica Turcica

Extracto: The results of the present study suggest that conventional CT has the potential to serve as a diagnostic tool for osteoporosis and may offer a more precise and accurate method for evaluating the success of intraosseous implants when compared to T-scores without the need for additional tests or procedures.

Cita:Acta Orthop Traumatol Turc 2023 Nov; 57 (6) : 384-388.

Autor/es:Imren, Yunus (a)
Karslioğlu, Bulent (b)

institución:(a) Department of Orthopedics and Traumatology, Health Sciences University Baltalimanı Metin Sabancı Bone Diseases Training and Research Hospital, İstanbul, Turkey.
(b) Department of Orthopedics and Traumatology, Health Sciences University Prof. Cemil Taşçıoğlu City Hospital, İstanbul, Turkey.

Formato:Informe impreso

Idioma:Inglés

País de fuente:Turquía

Sitio web:http://dx.doi.org/10.5152/j.aott.2023.23126

Intensive urate-lowering with pegloticase plus methotrexate co-therapy in uncontrolled gout patients with and without chronic kidney disease: A retrospective case series.

Fuente:Medicine

Extracto: No new safety signals were identified, with most CKD patients showing renal function stability or improvement during therapy.

Cita:Medicine (Baltimore) 2024 Mar 8; 103 (10) : e37424.

Autor/es:Albert, John (a)
Broadwell, Aaron (b)

institución:(a) Rheumatic Disease Center, Milwaukee, WI.
(b) Rheumatology and Osteoporosis Specialists, Shreveport, LA.

Formato:Informe impreso

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1097/MD.0000000000037424

Challenges of fracture risk assessment in Asian and Black women.

Fuente:The American Journal of Managed Care

Extracto: A large subset of Asian women have discordant BMD and FRAX scores, presenting challenges in osteoporosis management. Furthermore, FN-BMD and especially FRAX scores identified few Black women at high fracture risk warranting treatment. Studies should examine whether fracture risk assessment can be optimized in understudied racial minority populations, particularly when findings are discordant.

Cita:Am J Manag Care 2024 Mar; 30 (3) : 140-144.

Autor/es:Lo, Joan C (a)
Chandra, Malini (b)

institución:Lo, Joan C (a)
Chandra, Malini (b)

Formato:Informe impreso

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.37765/ajmc.2024.89515

An online clinical decision tool to screen for vertebral fragility fractures (Vfrac) in older women presenting with back pain in general practice

An online clinical decision tool to screen for vertebral fragility fractures (Vfrac) in older women presenting with back pain in general practice

Fuente:Archives of Osteoporosis

Tipo de trabajo:Estudio aleatorizado y controlado

Extracto: This article describes the protocol of the Vfrac feasibility study. TRIAL REGISTRATION: ISRCTN18000119 (registered 01/03/2022) and ISRCTN12150779 (registered 10/01/2022).

Claves:Back pain, Osteoporosis, Vertebral fractures, Vfrac

Cita:Arch Osteoporos 2024 Feb 7; 19 (1) : 12.

Autor/es:Khalid, Tanzeela Y (a)
Peters, Tim J (b)

institución:(a) Musculoskeletal Research Unit, Translational Health Sciences, Learning and Research Building, Southmead Hospital, Bristol Medical School, University of Bristol, Bristol, BS10 5NB, UK. t.khalid@bristol.ac.uk.
(b) Bristol Dental School, University of Bristol, Bristol, UK.

Conflicto:None.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1007/s11657-023-01364-1

circ_0029463 promotes osteoclast differentiation by mediating miR-134-5p/Rab27a axis.

circ_0029463 promotes osteoclast differentiation by mediating miR-134-5p/Rab27a axis.

Fuente:Journal of Orthopaedic Surgery and Research

Extracto: circ_0029463 sponges miR-134-5p to abolish its suppressive effect of miR-134-5p on Rab27a expression, thereby promoting osteoclast differentiation.

Claves:Osteoclast differentiation, Rab27a, circ_0029463, miR-134-5p

Cita:J Orthop Surg Res 2024 Feb 7; 19 (1) : 128.

Autor/es:Tang, Lian (a)
Yuan, Lin (b)

institución:(a) Department of Orthopedics, Affiliated Hospital of Southwest Medical University, No. 25 Taiping Street, Jiangyang District, Luzhou, 646000, Sichuan, People's Republic of China.
(b) Department of Clinical Skills Center, Affiliated Hospital of Southwest Medical University, Luzhou, 646000, Sichuan, People's Republic of China.

Conflicto:The authors declare there is no conflict of interests.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s13018-024-04610-5

Overexpression of SPP1 is a prognostic indicator of immune infiltration in lung adenocarcinoma.

Overexpression of SPP1 is a prognostic indicator of immune infiltration in lung adenocarcinoma.

Fuente:Aging

Extracto: SPP1 is a reliable indicator for assessing LUAD immune infiltration status and prognosis. With this approach, SPP1 can help earlier LUAD diagnosis and act as a possible immunotherapy target.

Claves:LUAD, SPP1, biomarker, prognosis, tumor-infiltrating immune cells

Cita:Aging (Albany NY) 2024 Feb 7; 16 (3) : 2953-2977.

Autor/es:Li, Binbin (a)
Li, Xue (b)

institución:(a) College of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Jinan 250014, China.
(b) College of Acupuncture and Massage, Shandong University of Traditional Chinese Medicine, Jinan 250014, China.

Formato:Informe impreso

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.18632/aging.205526

Repeatability of biometric measures from the IOLMaster 700 in a cataractous population.

Repeatability of biometric measures from the IOLMaster 700 in a cataractous population.

Fuente:Plos One

Extracto: The SD change over Mean for AL measurement and the correlations between the uncertainties of several biometric parameters mean that a simple Gaussian error propagation model cannot be used to derive the effect of biometric uncertainties on the predicted intraocular lens power and refraction after cataract surgery.

Cita:PLoS One 2024; 19 (2) : e0297869.

Autor/es:Langenbucher, Achim (a)
Szentmáry, Nóra (b)

institución:(a) Department of Experimental Ophthalmology, Saarland University, Homburg/Saar, Germany.
(b) Dr. Rolf M. Schwiete Center for Limbal Stem Cell and Aniridia Research, Saarland University, Homburg/Saar, Germany.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1371/journal.pone.0297869

Involvement of Cyclooxygenase-2 in Establishing an Immunosuppressive Microenvironment in Tumorspheres Derived from TMZ-Resistant Glioblastoma Cell Lines and Primary Cultures.

Involvement of Cyclooxygenase-2 in Establishing an Immunosuppressive Microenvironment in Tumorspheres Derived from TMZ-Resistant Glioblastoma Cell Lines and Primary Cultures.

Fuente:Cells

Extracto: COX-2 inhibition interfered with TMZ's ability to induce M2-polarization and counteracted the development of an immunosuppressive TME.

Claves:COX-2, COXIB, glioblastoma, macrophages, osteopontin, temozolomide, tumor microenvironment

Cita:Cells 2024 Jan 30; 13 (3)

Autor/es:Lombardi, Francesca (a)
Augello, Francesca Rosaria (b)

institución:(a) Department of Life, Health and Environmental Sciences, University of L'Aquila, 67100 L'Aquila, Italy.
(b) Department of Life, Health and Environmental Sciences, University of L'Aquila, 67100 L'Aquila, Italy.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3390/cells13030258

Longitudinal changes of the femoral bone mineral density from first to third trimester of pregnancy: bone health assessment by means of non-ionizing REMS technology.

Longitudinal changes of the femoral bone mineral density from first to third trimester of pregnancy: bone health assessment by means of non-ionizing REMS technology.

Fuente:Aging Clinical and Experimental Research

Extracto: Our study conducted on a cohort of healthy participants with uncomplicated pregnancy demonstrates that there is a significant reduction of bone mineral density at femoral neck from early to late gestation.

Claves:Bone density, Bone development, Calcium metabolism, Femur neck, Osteoporosis, Physiologic calcification

Cita:Aging Clin Exp Res 2024 Feb 9; 36 (1) : 31.

Autor/es:Ramirez Zegarra, Ruben (a)
Degennaro, Valentina (b)

institución:(a) Department of Medicine and Surgery, Obstetrics and Gynecology Unit, University of Parma, Viale A. Gramsci 14, 43126, Parma, Italy.
(b) Department of Medicine and Surgery, Obstetrics and Gynecology Unit, University of Parma, Viale A. Gramsci 14, 43126, Parma, Italy.

Conflicto:Casciaro S. and Conversano F. are co-founders and minority shareholders of Echolight Spa. Brandi M.L. is a scientific advisor at Echolight. Pisani P. is a scientific consultant at Echolight. All the remaining authors have no competing interests to declare that are relevant to the content of the article.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Alemania

Sitio web:http://dx.doi.org/10.1007/s40520-023-02677-4

Denosumab and the Risk of Diabetes in Patients Treated for Osteoporosis.

Denosumab and the Risk of Diabetes in Patients Treated for Osteoporosis.

Fuente:Jama Network Open

Tipo de trabajo:Estudio de cohortes

Extracto: AND RELEVANCE: The results from this cohort study indicating that denosumab treatment was associated with lower risk of incident diabetes may help physicians choose an appropriate antiosteoporosis medication for patients with osteoporosis while also considering the risk of diabetes.

Cita:JAMA Netw Open 2024 Feb 5; 7 (2) : e2354734.

Autor/es:Huang, Huei-Kai (a)
Chuang, Albert Tzu-Ming (b)

institución:(a) Department of Family Medicine and Department of Medical Research, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan.
(b) School of Medicine, Tzu Chi University, Hualien, Taiwan.

Conflicto:Conflict of Interest Disclosures: Dr Lai received funding from Amgen, Novartis, Pfizer, Sanofi, and Takeda, all outside the submitted work. Dr Shao received funding from Amgen and AbbVie, both outside the submitted work. No other disclosures were reported.

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1001/jamanetworkopen.2023.54734

Cerebrotendinous Xanthomatosis patients with late diagnosed in single orthopedic clinic: two novel variants in the CYP27A1 gene.

Cerebrotendinous Xanthomatosis patients with late diagnosed in single orthopedic clinic: two novel variants in the CYP27A1 gene.

Fuente:Orphanet Journal of Rare Diseases

Tipo de trabajo:Revisión

Extracto: We present the diagnostic process and clinical features which the largest CTX case series ever reported from single orthopedic clinic. We suggest that patients with normal cholesterol levels presenting with xanthoma being genetically analyzed by testing at their serum cholestanol level, and that all siblings of patients diagnosed with CTX be examined.

Claves:Achilles, Cerebrotendinous Xanthomatosis, Novel mutation, Tendon xanthomas

Cita:Orphanet J Rare Dis 2024 Feb 9; 19 (1) : 53.

Autor/es:Köroğlu, Muhammed (a)
Karakaplan, Mustafa (b)

institución:(a) Orthopaedics and Traumatology Department, Turgut Özal Medical Center, İnönü University Medical School, Malatya, 44280, Turkey.
(b) Orthopaedics and Traumatology Department, Turgut Özal Medical Center, İnönü University Medical School, Malatya, 44280, Turkey. karakaplanmb@gmail.com.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s13023-024-03082-4

Examining the pedagogical practices that support cultural proficiency development in graduate health science students.

Examining the pedagogical practices that support cultural proficiency development in graduate health science students.

Fuente:Bmc Medical Education

Tipo de trabajo:Consenso

Extracto: These findings highlight the need to utilize evidence-based pedagogical practices to design intentional, integrated, and holistic CP training throughout health science programs that employ an intersectional lens and empowers learners to serve as advocates for their patients and address systemic challenges.

Claves:Bias, Empathy, Inclusion, Instructional design, Osteopathic health sciences

Cita:BMC Med Educ 2024 Feb 9; 24 (1) : 130.

Autor/es:Speer, Julie E (a)
Conley, Quincy (b)

institución:(a) Teaching & Learning Center, A.T. Still University, 5835 E. Still Circle, Mesa, AZ, 85206, USA. juliespeer@atsu.edu.
(b) Teaching & Learning Center, A.T. Still University, 5835 E. Still Circle, Mesa, AZ, 85206, USA.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12909-024-05097-8

Effects of Multispecies Probiotic Supplementation on Serum Bone Turnover Markers in Postmenopausal Women with Osteopenia: A Randomized, Double-Blind, Placebo-Controlled Trial.

Effects of Multispecies Probiotic Supplementation on Serum Bone Turnover Markers in Postmenopausal Women with Osteopenia: A Randomized, Double-Blind, Placebo-Controlled Trial.

Fuente:Nutrients

Extracto: In conclusion, multispecies probiotics may have a preventive effect on bone through their antiresorptive effect in osteopenic postmenopausal women.

Claves:bone health, bone turnover markers, multispecies probiotics, osteopenia, postmenopausal bone health, postmenopausal women, probiotics, supplement

Cita:Nutrients 2024 Feb 5; 16 (3)

Autor/es:Vanitchanont, Marut (a)
Vallibhakara, Sakda Arj-Ong (b)

institución:(a) Reproductive Endocrinology and Infertility Unit, Department of Obstetrics and Gynaecology, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok 10400, Thailand.
(b) Child Safety Promotion and Injury Prevention Research Center, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok 10400, Thailand.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3390/nu16030461

Effect of Hyperprolactinemia on Bone Metabolism: Focusing on Osteopenia/Osteoporosis.

Effect of Hyperprolactinemia on Bone Metabolism: Focusing on Osteopenia/Osteoporosis.

Fuente:International Journal of Molecular Sciences

Extracto: This review highlights the recent work on bone remodeling and discusses our knowledge of how prolactin modulates these interactions, with a brief literature review on the relationship between prolactin and bone metabolism and suggestions for new possibilities.

Claves:bone metabolism, hyperprolactinemia, osteopenia, osteoporosis

Cita:Int J Mol Sci 2024 Jan 25; 25 (3)

Autor/es:Yun, Soo Jin (a)
Sang, Hyunji (b)

institución:(a) Department of Endocrinology and Metabolism, Kyung Hee University College of Medicine, Kyung Hee University Hospital, Seoul 02447, Republic of Korea.
(b) Department of Endocrinology and Metabolism, Kyung Hee University College of Medicine, Kyung Hee University Hospital, Seoul 02447, Republic of Korea.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3390/ijms25031474

Post-Transplant Bone Disease in Kidney Transplant Recipients: Diagnosis and Management.

Fuente:International Journal of Molecular Sciences

Extracto: In this review, we will discuss pathophysiology, risk assessment, diagnosis and management strategies to manage PTBD after kidney transplantation.

Claves:chronic kidney disease–mineral bone disease, kidney failure, kidney transplantation, osteoporosis, post-transplant bone disease

Cita:Int J Mol Sci 2024 Feb 3; 25 (3)

Autor/es:Teh, Jia Wei (a)
Mac Gearailt, Conall (b)

institución:(a) Department of Nephrology, Galway University Hospital, H91 YR71 Galway, Ireland.
(b) Department of Rheumatology, Galway University Hospital, H91 YR71 Galway, Ireland.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3390/ijms25031859

The effect of micro-osteoperforations on the rate of maxillary incisors' retraction in orthodontic space closure: a randomized controlled clinical trial.

The effect of micro-osteoperforations on the rate of maxillary incisors' retraction in orthodontic space closure: a randomized controlled clinical trial.

Fuente:Progress in Orthodontics

Tipo de trabajo:Estudio clínico

Extracto: MOPs did not accelerate the retraction of the maxillary incisors, nor were they associated with greater incisor inclination or root resorption. Trial registration ClinicalTrials.gov NCT03089996. Registered 24 March 2017- https://clinicaltrials.gov/ct2/show/NCT03089996 .

Claves:Orthodontic appliances, Root resorption, Tooth movement techniques

Cita:Prog Orthod 2024 Feb 12; 25 (1) : 6.

Autor/es:Mordente, Carolina Morsani (a)
Oliveira, Dauro Douglas (b)

institución:(a) Graduate Program in Dentistry, School of Dentistry, Pontifical Catholic University of Minas Gerais, Belo Horizonte, MG, Brazil.
(b) Graduate Program in Dentistry, Department of Orthodontics, Pontifical Catholic University of Minas Gerais, Belo Horizonte, MG, Brazil.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Alemania

Sitio web:http://dx.doi.org/10.1186/s40510-023-00505-z

MicroRNA-877-5p promotes osteoblast differentiation by targeting EIF4G2 expression.

MicroRNA-877-5p promotes osteoblast differentiation by targeting EIF4G2 expression.

Fuente:Journal of Orthopaedic Surgery and Research

Extracto: These results indicate that miR-877-5p might have a therapeutic application related to its promotion of bone formation through targeting EIF4G2.

Claves:EIF4G2, MC3T3-E1, Osteoblast differentiation, miR-877-5p

Cita:J Orthop Surg Res 2024 Feb 12; 19 (1) : 134.

Autor/es:Shen, YingChao (a)
Zhang, Yang (b)

institución:(a) Department of Orthopaedics, Changshu Hospital Affiliated to Nanjing University of Chinese Medicine, No. 6 Huanghe Road, ChangShu City, 215500, China.
(b) School of Biology and Food Engineering, Changshu Institute of Technology, Changshu City, 215500, Jiangsu, China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s13018-023-04396-y

Exploring the relationship of supernumerary recurrent renal calculi formation and tick-borne infections

Exploring the relationship of supernumerary recurrent renal calculi formation and tick-borne infections

Fuente:Frontiers in Cellular and Infection Microbiology

Tipo de trabajo:Caso clínico

Extracto: This case raises questions of etiology including possible immune deficiency and whether his uncommon microbial history contributes to recurrent stone formation.

Claves:Babesia, Bartonella, Borrelia, Cacchi-Ricci disease, medullary sponge kidney, nephrolithiasis, renal calculi, tick-borne infections

Cita:Front Cell Infect Microbiol 2024; 14 : 1194307.

Autor/es:Paz, Dean C (a)
Gunther, Abigael C (b)

institución:(a) Rocky Vista University College of Osteopathic Medicine, Parker, CO, United States.
(b) Rocky Vista University College of Osteopathic Medicine, Parker, CO, United States.

Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3389/fcimb.2024.1194307

Evaluating adherence, tolerability and safety of oral calcium citrate in elderly osteopenic subjects: a real-life non-interventional, prospective, multicenter study.

Evaluating adherence, tolerability and safety of oral calcium citrate in elderly osteopenic subjects: a real-life non-interventional, prospective, multicenter study.

Fuente:Aging Clinical and Experimental Research

Extracto: This study demonstrated favorable adherence to calcium citrate supplementation in elderly osteopenic subjects. The occurrence of ARs, though generally mild, were associated with lower adherence to calcium supplementation.

Claves:Adherence, Adverse reaction, Calcium citrate, Osteoporosis, Supplementation

Cita:Aging Clin Exp Res 2024 Feb 12; 36 (1) : 38.

Autor/es:Rondanelli, Mariangela (a)
Minisola, Salvatore (b)

institución:(a) Department of Public Health, Experimental and Forensic Medicine, University of Pavia, Via Forlanini, 2, 27100, Pavia, Italy. mariangela.rondanelli@unipv.it.
(b) Department of Clinical, Internal, Anesthesiological and Cardiological Sciences, "Sapienza" University of Rome, Rome, Italy.

Conflicto:MR received consultancy fees from Abiogen Pharma; SM served as speaker for Abiogen Pharma, Bruno Farmaceutici, Diasorin, Geopharma, Sandoz, UCB and he also served on the advisory board for Abiogen Pharma, Eli Lilly, Kyowa Kirin, Novo Nordisk, UCB; GB received research grant to Institution from Abiogen Pharma and Savio Pharma; MB participated in advisory board for Sandoz; SB and FN... are employees of Abiogen Pharma. SC2 received Institution research grant from Sandoz and Gedeon Richter; CM has non-conditional relationship with Abiogen Pharma; RG has a non-conditional relationship with IBSA Farmaceutici Italia, Bruno Farmaceutici, Abiogen Pharma, Amgen, Savio Pharma Italia; All remaining authors declare no conflict of interest.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Alemania

Sitio web:http://dx.doi.org/10.1007/s40520-024-02696-9

Spinal osteoarthritis is a risk of vertebral fractures in postmenopausal women.

Spinal osteoarthritis is a risk of vertebral fractures in postmenopausal women.

Fuente:Scientific Reports

Extracto: The presence of spinal OA is a risk factor for incident vertebral fractures despite high lumbar BMD.

Claves:Bone mineral density, Fracture risk, Osteoarthritis

Cita:Sci Rep 2024 Feb 12; 14 (1) : 3528.

Autor/es:Kuroda, Tatsuhiko (a)
Shiraki, Masataka (b)

institución:(a) Public Health Research Foundation, Shinjuku-ku, Tokyo, Japan.
(b) Research Institute and Practice for Involutional Diseases, Azumino City, Nagano, Japan.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1038/s41598-024-53994-1