Links among Obesity, Type 2 Diabetes Mellitus, and Osteoporosis: Bone as a Target.

Links among Obesity, Type 2 Diabetes Mellitus, and Osteoporosis: Bone as a Target.

Fuente:International Journal of Molecular Sciences

Extracto: The implementation of better diagnostic tools, including trabecular bone score, lumbar spine BMD/body mass index (BMI) ratio, and microRNAs to predict bone fragility, could improve fracture prevention in this patient group.

Claves:BMD, adipose tissue, bone tissue, fracture risk, obesity, osteoporosis, treatment, type 2 diabetes mellitus

Cita:Int J Mol Sci 2024 Apr 28; 25 (9)

Autor/es:Martiniakova, Monika (a)
Biro, Roman (b)

institución:(a) Department of Zoology and Anthropology, Faculty of Natural Sciences and Informatics, Constantine the Philosopher University in Nitra, 949 01 Nitra, Slovakia.
(b) Department of Zoology and Anthropology, Faculty of Natural Sciences and Informatics, Constantine the Philosopher University in Nitra, 949 01 Nitra, Slovakia.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3390/ijms25094827

Novel cardiac extracellular matrix biomarkers in STEMI: Associations with ischemic injury and long-term mortality.

Novel cardiac extracellular matrix biomarkers in STEMI: Associations with ischemic injury and long-term mortality.

Fuente:Plos One

Extracto: In patients with STEMI, we found an association between serum levels of ECM biomarkers and ischemic injury and mortality. The results provide new insight into the role ECM components play in ischemic injury following STEMI and suggests a potential for these biomarkers in prognostication after STEMI.

Cita:PLoS One 2024; 19 (5) : e0302732.

Autor/es:Andrup, Simon (a)
Andersen, Geir Ø (b)

institución:(a) Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
(b) Department of Cardiology, Oslo University Hospital Ullevål, Oslo, Norway.

Conflicto:I have read the journal’s policy and the authors of this manuscript have the following competing interests: A patent application filed by the University of Oslo covering the use of ECM enzyme inhibitor in cardiac remodelling and heart failure (WO2015004209A1) is granted in Europe (EP3756667A1) and granted in the United States (US10744155B2), where MV is among the inventors. Related to... to this patent, the University of Oslo has a licence agreement with the pharmaceutical company Paradigm Biopharma for the development of pentosane polysulfate in the treatment of cardiac remodelling and heart failure, and MV has performed consulting services for Paradigm to support this development. MV has participated in advisory boards for Pharmacosmos and AstraZeneca, on the topics iron supplementation and the use of sodium-glucose cotransporter 2 inhibitors in heart failure. The authors declare no other conflicts of interest related to the content of this manuscript.

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1371/journal.pone.0302732

Adjunctive Use of Bone Growth Stimulation Increases Cervical Spine Fusion Rates in Patients at Risk for Pseudarthrosis.

Fuente:Clinical Spine Surgery

Tipo de trabajo:Estudio clínico

Extracto: Adjunctive use of PEMF stimulation provides significant improvements in cervical spine fusion rates in subjects having risk factors for pseudarthrosis. When compared with control subjects that did not use PEMF stimulation, treated subjects showed improved fusion outcomes despite being older, having more risk factors for pseudarthrosis, and undergoing more complex surgeries.

Cita:Clin Spine Surg 2024 May 1; 37 (4) : 124-130.

Autor/es:Patel, Vikas (a)
Wind, Joshua J (b)

institución:(a) Department of Orthopedic Surgery, University of Colorado School of Medicine, Aurora, CO.
(b) Washington Neurological Associates, Sibley Memorial Hospital, Washington, DC.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe impreso

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1097/BSD.0000000000001615

Unlocking Therapeutic Potential: The Role of Theta Burst Stimulation in Multiple Sclerosis Management.

Fuente:The Primary Care Companion For Cns Disorders

Tipo de trabajo:Revisión sistemática

Extracto: Author affiliations are listed at the end of this article.

Cita:Prim Care Companion CNS Disord 2024 Apr 18; 26 (2)

Autor/es:Lo, David F (a)
Palhang, Meejan (b)

institución:(a) New Jersey Institute for Successful Aging, Rowan-Virtua School of Osteopathic Medicine, Stratford, New Jersey.
(b) American Preventive Screening & Education Association, Stratford, New Jersey.

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.4088/PCC.23r03645

Excimer Laser Therapy for Pigmented Purpuric Dermatosis: A Case Study.

Fuente:The American Journal of Case Reports

Extracto: PPD is notoriously difficult to treat, and historic treatment options include topical corticosteroids, oral supplements, and immunomodulators, all of which come with a range of adverse effects. However, new literature supports the use of phototherapy to treat PPD, with varying results. Previously implemented options include but are not limited to phototherapy with psoralen plus ultraviolet A, narrow band ultraviolet B, advanced fluorescence technology pulsed light, and fractional non-ablative 1540-nm erbium: glass laser, each with varying degrees of success. This case discusses the successful treatment of recalcitrant PPD with excimer laser therapy and maintenance of remission for approximately 1 year.

Cita:Am J Case Rep 2024 May 3; 25 : e942853.

Autor/es:Myers, Hannah (a)
Ceci, Francesca M (b)

institución:(a) Department of Dermatology, Medical College of Georgia, Augusta, GA, USA.
(b) Department of Dermatology, Philadelphia College of Osteopathic Medicine, Atlanta, GA, USA.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.12659/AJCR.942853

Prevalence of Musculoskeletal and Metabolic Disorders in Kidney Transplant Recipients

Fuente:Transplant International Official Journal of The European Society For Organ Transplantation

Tipo de trabajo:Revisión sistemática

Extracto: The most common musculoskeletal disorders were low muscle strength, femoral osteopenia, and low muscle mass. Hypovitaminosis D, hyperparathyroidism, and hyperuricemia were also the most common metabolic disorders. These disorders could be associated with poorer quality of life in kidney transplant recipients. SYSTEMATIC REVIEW REGISTRATION: https://www.crd.york.ac.uk/prospero/, identifier [CRD42023449171].

Claves:meta-analysis, metabolic, musculoskeletal, proportion, renal transplant

Cita:Transpl Int 2024; 37 : 12312.

Autor/es:Herreros-Carretero, Álvaro (a)
Berlanga-Macías, Carlos (b)

institución:(a) Facultad de Enfermería, Universidad de Castilla-La Mancha, Albacete, Spain.
(b) Facultad de Enfermería, Universidad de Castilla-La Mancha, Albacete, Spain.

Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3389/ti.2024.12312

Analysis and validation of biomarkers of immune cell-related genes in postmenopausal osteoporosis: An observational study.

Fuente:Medicine

Extracto: HIST1H2AG, PYGM, NCKAP1, POMP, and LYPLA1 might play key roles in PMOP and be served as the biomarkers of PMOP.

Cita:Medicine (Baltimore) 2024 May 10; 103 (19) : e38042.

Autor/es:Chen, Lihua (a)
Zhao, Yu (b)

institución:(a) Rehabilitation Department, Shenzhen Bao'an Traditional Chinese Medicine Hospital, Guangzhou University of Chinese Medicine, Shenzhen, PR China.
(b) Osteoporosis Department, Shenzhen Hospital of Integrated Traditional Chinese and Western Medicine, Shenzhen, PR China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe impreso

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1097/MD.0000000000038042

Full-Endoscopic Foraminal Decompression for Foraminal Stenosis Following Osteoporotic Vertebral Fracture in an Elderly Woman Under Local Anesthesia

Fuente:The Journal of Medical Investigation Jmi

Tipo de trabajo:Caso clínico

Extracto: 71 : 179-183, February, 2024.

Claves:aged population, foraminal stenosis, full-endoscopic spine surgery, local anesthesia, osteoporotic vertebral fracture

Cita:J Med Invest 2024; 71 (1.2) : 179-183.

Autor/es:Otake, Yu (a)
Tezuka, Fumitake (b)

institución:(a) Department of Orthopedics, Tokushima University, Tokushima, Japan.
(b) Department of Orthopedic Surgery, St. Lukas Hospital, Tokyo, Japan.

Formato:Informe impreso

Idioma:Inglés

País de fuente:Japón

Sitio web:http://dx.doi.org/10.2152/jmi.71.179

[Determination of multiple residual solvents in ibandronate sodium using headspace-gas chromatography].

Fuente:Se Pu = Chinese Journal of Chromatography

Extracto: This study has important practical significance in improving drug safety and ensuring public health.

Claves:1-pentanol, headspace-gas chromatography (HS-GC), ibandronate sodium, residual solvents

Cita:Se Pu 2024 Apr 8; 42 (5) : 481-486.

Autor/es:Zhou, Ran (a)
Wang, Fei (b)

institución:(a) College of Chemical Engineering, Shijiazhuang University, Shijiazhuang 050035, China.
(b) Research Department, Shijiazhuang University, Shijiazhuang 050035, China.

Formato:Informe impreso

Idioma:chi

País de fuente:China

Sitio web:http://dx.doi.org/10.3724/SP.J.1123.2024.01023

The role of bone turnover markers in diagnosis, monitoring, and pathological fractures of osteoporosis.

Fuente:Ulusal Travma Ve Acil Cerrahi Dergisi = Turkish Journal of Trauma & Emergency Surgery Tjtes

Extracto: Our study underscores the significance of these biomarkers in advancing the diagnosis and management of osteo-porosis, offering valuable insights into the disease's progression and treatment outcomes.

Cita:Ulus Travma Acil Cerrahi Derg 2024 May; 30 (5) : 323-327.

Autor/es:Altınsoy, Kazım Ersin (a)
Unat, Beytullah (b)

institución:(a) Department of Emergency Medicine, Faculty of Medicine, Gaziantep Islam Science and Technology University, Gaziantep-Türkiye.
(b) Department of Orthopedics and Traumatology, Gaziantep City Hospital, Gaziantep-Türkiye.

Formato:Informe impreso

Idioma:Inglés

País de fuente:Turquía

Sitio web:http://dx.doi.org/10.14744/tjtes.2024.48409

Iron status and sarcopenia-related traits: a bi-directional Mendelian randomization study.

Iron status and sarcopenia-related traits: a bi-directional Mendelian randomization study.

Fuente:Scientific Reports

Extracto: These findings contribute to our understanding of the complex interplay between iron metabolism and muscle health.

Claves:Causality, Ferritin, Iron status, Multivariable mendelian randomization, Sarcopenia

Cita:Sci Rep 2024 Apr 22; 14 (1) : 9179.

Autor/es:Chen, Honggu (a)
Zhang, Ziyi (b)

institución:(a) Department of Orthopedics, the Affiliated Hospital of Jiangsu University, Zhenjiang, 212000, Jiangsu Province, People's Republic of China.
(b) Department of Orthopedics, the Affiliated Hospital of Jiangsu University, Zhenjiang, 212000, Jiangsu Province, People's Republic of China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1038/s41598-024-60059-w

Prevalence of sarcopenic obesity in the older non-hospitalized population

Prevalence of sarcopenic obesity in the older non-hospitalized population

Fuente:Bmc Geriatrics

Tipo de trabajo:Revisión sistemática

Extracto: SO prevalence is high among non-hospitalized older adults, especially those with functional and cognitive impairments. Thus, SO is a potential problem for the aging population; implementation of planned interventions in the community is needed to reduce the prevalence and adverse outcomes of SO.

Claves:Meta-analysis, Older adults, Prevalence, Sarcopenic obesity, Systematic review

Cita:BMC Geriatr 2024 Apr 22; 24 (1) : 357.

Autor/es:Luo, Yuhong (a)
Wang, Yanqiu (b)

institución:(a) School of Nursing, Capital Medical University, Beijing, China.
(b) Xuanwu Hospital, Capital Medical University, No 45., Changchun Street, Xicheng District, 100055, Beijing, China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12877-024-04952-z

Pregnancy and lactation-associated osteoporosis as a major type of premenopausal osteoporosis

Pregnancy and lactation-associated osteoporosis as a major type of premenopausal osteoporosis

Fuente:Bmc Pregnancy and Childbirth

Tipo de trabajo:Estudio de cohortes

Extracto: PLO with vertebral fracture was one of the major types of premenopausal osteoporosis. The prevalence of PLO is considered to be higher than previously thought, indicating the presence of potentially overlooked patients. More timely interventions for PLO might lead to the improved management of latent patients with premenopausal osteoporosis and reduce future fracture risk.

Claves:Fracture, Lactation, Osteoporosis, Pregnancy, Premenopausal

Cita:BMC Pregnancy Childbirth 2024 Apr 22; 24 (1) : 301.

Autor/es:Kasahara, Kyoko (a)
Tanaka-Mizuno, Sachiko (b)

institución:(a) The Department of Obstetrics and Gynecology, Shiga University of Medical Science, Otsu, Shiga, Japan. kasabee@belle.shiga-med.ac.jp.
(b) The Laboratory of Epidemiology and Prevention, Kobe Pharmaceutical University, Kobe, Japan.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12884-024-06520-0

"The least significant change on bone mineral density scan increased in patients with higher degrees of obesity".

"The least significant change on bone mineral density scan increased in patients with higher degrees of obesity".

Fuente:Aging Clinical and Experimental Research

Extracto: LSC of 0.05 g/cm² could be used in clinical practice in patients with class 2 or 3 obesity. These findings should help to improve the interpretation of BMD scans in these patients and optimize their management. TRIAL REGISTRATION NUMBER: Comité de Protection des Personnes Ile-de France VII, France.

Claves:Bone mineral density, DXA, Least significant change, Obesity, Osteoporosis

Cita:Aging Clin Exp Res 2024 Apr 23; 36 (1) : 98.

Autor/es:Dorilleau, Claire (a)
Kanagaratnam, Lukshe (b)

institución:(a) Rheumatology Department, University Hospital Center of Reims, 45 Rue Cognacq-Jay, Reims, Reims, 51092, France.
(b) Department of Clinical Research and Innovation, University Hospital Center of Reims, Reims, France.

Conflicto:The authors declare that they have no financial or non-financial conflict of interest directly or indirectly related to the completion of this research work and the publication of the work submitted for publication.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Alemania

Sitio web:http://dx.doi.org/10.1007/s40520-024-02736-4

The process of hip fracture management before and during the COVID-19 pandemic in Iran.

The process of hip fracture management before and during the COVID-19 pandemic in Iran.

Fuente:Bmc Geriatrics

Extracto: The study suggests that the COVID-19 pandemic did not have a negative impact on hip fracture management in the investigated orthopedic hospital in Iran. further research is needed to explore the effects of the pandemic on other aspects of healthcare services, particularly in general hospitals.

Claves:Bone, COVID-19 pandemic, Hip fracture, Iran, Osteoporosis

Cita:BMC Geriatr 2024 Apr 23; 24 (1) : 359.

Autor/es:Yalamchi, Fatemeh (a)
Khalagi, Kazem (b)

institución:(a) Department of Epidemiology, School of Public Health, Iran University of Medical Sciences, Tehran, Iran.
(b) Osteoporosis Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12877-024-04839-z

Diabetes and osteoporosis: a two-sample mendelian randomization study.

Diabetes and osteoporosis: a two-sample mendelian randomization study.

Fuente:Bmc Musculoskeletal Disorders

Extracto: Our results showed that T1D and T2D have different effects on BMD at the genetic level. BMD decreased in patients with T1D and increased in those with T2D. These findings highlight the complex interplay between diabetes and bone health, suggesting potential age-specific effects and genetic influences. To better understand the mechanisms of bone metabolism in patients with diabetes, further longitudinal studies are required to explain BMD changes in different types of diabetes.

Claves:Bone mineral density, Diabetes, Fracture, Mendelian randomization, Osteoporosis

Cita:BMC Musculoskelet Disord 2024 Apr 23; 25 (1) : 317.

Autor/es:Qu, Yu-Dun (a)
Zhu, Zhao-Hua (b)

institución:(a) The Second School of Clinical Medicine, Guangdong Second Provincial General Hospital, Southern Medical University, Guangzhou, Guangdong, P.R. China.
(b) Clinical Research Centre, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong, China.

Conflicto:All other authors declare no competing interests.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12891-024-07430-0

Endocrine, auxological and metabolic profile in children and adolescents with Down syndrome: from infancy to the first steps into adult life.

Endocrine, auxological and metabolic profile in children and adolescents with Down syndrome: from infancy to the first steps into adult life.

Fuente:Frontiers in Endocrinology

Extracto: By performing a review of published literature, we highlighted the issues specifically involving children and adolescent with DS, aiming at providing clinicians with a detailed up-to-date overview of the endocrine, metabolic and auxological disorders in this selected population, with an additional focus on the management of patients in the critical phase of the transitioning from childhood to adult care.

Claves:Down syndrome, diabetes mellitus, hyperthyroidism, hypogonadism, hypothyroidism, obesity, osteopenia, osteoporosis

Cita:Front Endocrinol (Lausanne) 2024; 15 : 1348397.

Autor/es:Molinari, Silvia (a)
Fossati, Chiara (b)

institución:(a) Department of Pediatrics, Fondazione IRCCS San Gerardo dei Tintori, Monza, Italy.
(b) School of Medicine and Surgery, University of Milano-Bicocca, Milano, Italy.

Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. The author(s) declared that they were an editorial board member of Frontiers, at the time of submission. This had no impact on the peer review process and the final decision.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3389/fendo.2024.1348397

Deep learning in the radiologic diagnosis of osteoporosis

Deep learning in the radiologic diagnosis of osteoporosis

Fuente:The Journal of International Medical Research

Tipo de trabajo:Revisión

Extracto: Deep learning has demonstrated a remarkable capacity for osteoporosis screening. However, clinical commercialization of a diagnostic model for osteoporosis remains a challenge.

Claves:Osteoporosis, bone mineral density, convolutional neural network, deep learning, literature review, screening

Cita:J Int Med Res 2024 Apr; 52 (4) : 3000605241244754.

Autor/es:He, Yu (a)
Lin, Jiaxi (b)

institución:(a) Suzhou Medical College, Soochow University, Suzhou, Jiangsu, China.
(b) Department of Gastroenterology, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China. RINGGOLD: 74566

Conflicto:Declaration of conflicting interestThe authors declare that there is no conflict of interest.

Formato:Informe impreso

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1177/03000605241244754

Health Perceptions, Multimorbidity, and New Fractures and Mortality Among Patients With a Fracture.

Health Perceptions, Multimorbidity, and New Fractures and Mortality Among Patients With a Fracture.

Fuente:Jama Network Open

Tipo de trabajo:Estudio de cohortes

Extracto: AND RELEVANCE: In this cohort study, both CCI and SRH measures were associated with increased risk of subsequent fractures and mortality after fracture, underscoring the importance of managing the care of patients with comorbidities who sustain a fracture.

Cita:JAMA Netw Open 2024 Apr 1; 7 (4) : e248491.

Autor/es:Alarkawi, Dunia (a)
Tran, Thach S (b)

institución:(a) Bone Epidemiology, Clinical and Translation Science Lab, Garvan Institute of Medical Research, University of New South Wales, Sydney, New South Wales, Australia.
(b) Bone Epidemiology, Clinical and Translation Science Lab, Garvan Institute of Medical Research, University of New South Wales, Sydney, New South Wales, Australia.

Conflicto:Conflict of Interest Disclosures: Dr March reported receiving grants from Osteoporosis Australia Amgen received at the institution to fund data access during the conduct of the study. Dr Blank reported receiving royalties from Wolters Kluwer, editorial stipends from Elsevier and the Endocrine Society, and consulting fees from Guidepoint; owning stock in Abbott Laboratories, AbbVie, Amgen, Doctorpedia, GlaxoSmithKline, JangoBio, Johnson &... Johnson, Procter & Gamble, and ROMTech outside the submitted work; having a patent pending for a bone health assessment risk tool; and being an officer of the International Federation of Musculoskeletal Research Societies and the International Society for Clinical Densitometry. Dr Center reported receiving personal fees from Amgen for educational talks and serving on advisory boards outside the submitted work. No other disclosures were reported.

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1001/jamanetworkopen.2024.8491

Dietary inflammatory pattern and risk of hip fracture in the Nurses' Health Study.

Dietary inflammatory pattern and risk of hip fracture in the Nurses' Health Study.

Fuente:Archives of Osteoporosis

Extracto: A pro-inflammatory dietary pattern was associated with an increased risk of hip fracture among postmenopausal women.

Claves:Dietary pattern, Hip fracture, Immune system, Postmenopause

Cita:Arch Osteoporos 2024 Apr 24; 19 (1) : 33.

Autor/es:Dahl, Jesper (a)
Meyer, Haakon E (b)

institución:(a) Norwegian Institute of Public Health, Skøyen, PO Box 222, 0213, Oslo, Norway. jesper.dahl@fhi.no.
(b) Norwegian Institute of Public Health, Skøyen, PO Box 222, 0213, Oslo, Norway.

Conflicto:None.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1007/s11657-024-01385-4