Diabetes and osteoporosis: a two-sample mendelian randomization study.

Diabetes and osteoporosis: a two-sample mendelian randomization study.

Fuente:Bmc Musculoskeletal Disorders

Extracto: Our results showed that T1D and T2D have different effects on BMD at the genetic level. BMD decreased in patients with T1D and increased in those with T2D. These findings highlight the complex interplay between diabetes and bone health, suggesting potential age-specific effects and genetic influences. To better understand the mechanisms of bone metabolism in patients with diabetes, further longitudinal studies are required to explain BMD changes in different types of diabetes.

Claves:Bone mineral density, Diabetes, Fracture, Mendelian randomization, Osteoporosis

Cita:BMC Musculoskelet Disord 2024 Apr 23; 25 (1) : 317.

Autor/es:Qu, Yu-Dun (a)
Zhu, Zhao-Hua (b)

institución:(a) The Second School of Clinical Medicine, Guangdong Second Provincial General Hospital, Southern Medical University, Guangzhou, Guangdong, P.R. China.
(b) Clinical Research Centre, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong, China.

Conflicto:All other authors declare no competing interests.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12891-024-07430-0

Endocrine, auxological and metabolic profile in children and adolescents with Down syndrome: from infancy to the first steps into adult life.

Endocrine, auxological and metabolic profile in children and adolescents with Down syndrome: from infancy to the first steps into adult life.

Fuente:Frontiers in Endocrinology

Extracto: By performing a review of published literature, we highlighted the issues specifically involving children and adolescent with DS, aiming at providing clinicians with a detailed up-to-date overview of the endocrine, metabolic and auxological disorders in this selected population, with an additional focus on the management of patients in the critical phase of the transitioning from childhood to adult care.

Claves:Down syndrome, diabetes mellitus, hyperthyroidism, hypogonadism, hypothyroidism, obesity, osteopenia, osteoporosis

Cita:Front Endocrinol (Lausanne) 2024; 15 : 1348397.

Autor/es:Molinari, Silvia (a)
Fossati, Chiara (b)

institución:(a) Department of Pediatrics, Fondazione IRCCS San Gerardo dei Tintori, Monza, Italy.
(b) School of Medicine and Surgery, University of Milano-Bicocca, Milano, Italy.

Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. The author(s) declared that they were an editorial board member of Frontiers, at the time of submission. This had no impact on the peer review process and the final decision.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3389/fendo.2024.1348397

Deep learning in the radiologic diagnosis of osteoporosis

Deep learning in the radiologic diagnosis of osteoporosis

Fuente:The Journal of International Medical Research

Tipo de trabajo:Revisión

Extracto: Deep learning has demonstrated a remarkable capacity for osteoporosis screening. However, clinical commercialization of a diagnostic model for osteoporosis remains a challenge.

Claves:Osteoporosis, bone mineral density, convolutional neural network, deep learning, literature review, screening

Cita:J Int Med Res 2024 Apr; 52 (4) : 3000605241244754.

Autor/es:He, Yu (a)
Lin, Jiaxi (b)

institución:(a) Suzhou Medical College, Soochow University, Suzhou, Jiangsu, China.
(b) Department of Gastroenterology, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China. RINGGOLD: 74566

Conflicto:Declaration of conflicting interestThe authors declare that there is no conflict of interest.

Formato:Informe impreso

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1177/03000605241244754

Health Perceptions, Multimorbidity, and New Fractures and Mortality Among Patients With a Fracture.

Health Perceptions, Multimorbidity, and New Fractures and Mortality Among Patients With a Fracture.

Fuente:Jama Network Open

Tipo de trabajo:Estudio de cohortes

Extracto: AND RELEVANCE: In this cohort study, both CCI and SRH measures were associated with increased risk of subsequent fractures and mortality after fracture, underscoring the importance of managing the care of patients with comorbidities who sustain a fracture.

Cita:JAMA Netw Open 2024 Apr 1; 7 (4) : e248491.

Autor/es:Alarkawi, Dunia (a)
Tran, Thach S (b)

institución:(a) Bone Epidemiology, Clinical and Translation Science Lab, Garvan Institute of Medical Research, University of New South Wales, Sydney, New South Wales, Australia.
(b) Bone Epidemiology, Clinical and Translation Science Lab, Garvan Institute of Medical Research, University of New South Wales, Sydney, New South Wales, Australia.

Conflicto:Conflict of Interest Disclosures: Dr March reported receiving grants from Osteoporosis Australia Amgen received at the institution to fund data access during the conduct of the study. Dr Blank reported receiving royalties from Wolters Kluwer, editorial stipends from Elsevier and the Endocrine Society, and consulting fees from Guidepoint; owning stock in Abbott Laboratories, AbbVie, Amgen, Doctorpedia, GlaxoSmithKline, JangoBio, Johnson &... Johnson, Procter & Gamble, and ROMTech outside the submitted work; having a patent pending for a bone health assessment risk tool; and being an officer of the International Federation of Musculoskeletal Research Societies and the International Society for Clinical Densitometry. Dr Center reported receiving personal fees from Amgen for educational talks and serving on advisory boards outside the submitted work. No other disclosures were reported.

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1001/jamanetworkopen.2024.8491

Dietary inflammatory pattern and risk of hip fracture in the Nurses' Health Study.

Dietary inflammatory pattern and risk of hip fracture in the Nurses' Health Study.

Fuente:Archives of Osteoporosis

Extracto: A pro-inflammatory dietary pattern was associated with an increased risk of hip fracture among postmenopausal women.

Claves:Dietary pattern, Hip fracture, Immune system, Postmenopause

Cita:Arch Osteoporos 2024 Apr 24; 19 (1) : 33.

Autor/es:Dahl, Jesper (a)
Meyer, Haakon E (b)

institución:(a) Norwegian Institute of Public Health, Skøyen, PO Box 222, 0213, Oslo, Norway. jesper.dahl@fhi.no.
(b) Norwegian Institute of Public Health, Skøyen, PO Box 222, 0213, Oslo, Norway.

Conflicto:None.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1007/s11657-024-01385-4

Quantitative analysis and stochastic modeling of osteophyte formation and growth process on human vertebrae based on radiographs: a follow-up study.

Quantitative analysis and stochastic modeling of osteophyte formation and growth process on human vertebrae based on radiographs: a follow-up study.

Fuente:Scientific Reports

Extracto: The measured follow-up data is shared for future studies.

Cita:Sci Rep 2024 Apr 24; 14 (1) : 9393.

Autor/es:Wu, Tong (a)
Wang, Changxi (b)

institución:(a) West China Biomedical Big Data Center, West China Hospital, Sichuan University, Chengdu, 610041, China.
(b) West China Biomedical Big Data Center, West China Hospital, Sichuan University, Chengdu, 610041, China. changxi.wang@scu.edu.cn.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1038/s41598-024-60212-5

Effectiveness of atopic dermatitis patient education programs - a systematic review and meta-analysis.

Effectiveness of atopic dermatitis patient education programs - a systematic review and meta-analysis.

Fuente:Archives of Dermatological Research

Extracto: Future research on educational interventions should utilize various methodologies to encourage individual learning preferences with a focus on adult cohorts.

Claves:Atopic dermatitis, Dermatitis, Eczema, Education, Public health

Cita:Arch Dermatol Res 2024 Apr 25; 316 (5) : 135.

Autor/es:Andrade, Luis F (a)
Abdi, Parsa (b)

institución:(a) Dr. Phillip Frost Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, 1150 NW 14th Street, Miami, FL, 33136, USA. luisandrade@med.miami.edu.
(b) Faculty of Medicine, Memorial University of Newfoundland, 300 Prince Philip Dr, St. John's, NL, A1B 3V6, Canada.

Conflicto:Conflicts of interest for Dr. Gil Yosipovitch include: Consultant And Board member Sanofi, Regeneron, Pfizer, Galderma, Novartis, Eli Lilly, Abbvie, Kiniksa, Trevi, Pierre Gabre, LEo, Escient. Celldex, Bellus, Research support Pfizer, Sanofi Regeneron, Leo, Eli Lilly, Kiniksa, Novartis, Escient, Bellus Galderma, Celldex.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Alemania

Sitio web:http://dx.doi.org/10.1007/s00403-024-02871-y

Understanding primary care providers' attitudes towards preventive screenings to patients with inflammatory bowel disease.

Understanding primary care providers' attitudes towards preventive screenings to patients with inflammatory bowel disease.

Fuente:Plos One

Tipo de trabajo:Revisión

Extracto: Despite a general comfort among PCPs in recommending preventive screenings for IBD patients, gaps in knowledge regarding IBD-specific screening guidelines persist. Enhancing awareness and understanding of these guidelines through targeted education and resource provision may bridge this gap.

Cita:PLoS One 2024; 19 (4) : e0299890.

Autor/es:Xu, Fang (a)
Carlson, Susan A (b)

institución:(a) Division of Population Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America.
(b) Division of Population Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1371/journal.pone.0299890

The Expression and Secretion Profile of TRAP5 Isoforms in Gaucher Disease.

The Expression and Secretion Profile of TRAP5 Isoforms in Gaucher Disease.

Fuente:Cells

Extracto: As an early indicator of BMD alteration, measurement of circulating TRAP5b is a valuable tool for assessing osteopenia-osteoporosis in GD, while TRAP5a serves as a biomarker of macrophage activation in GD. Understanding the distinct expression pattern of TRAP5 isoforms offers valuable insight into both bone disease and the broader implications for immune system activation in GD.

Claves:Gaucher cells, Gaucher disease, TRAP, bone, inflammation, macrophages, osteoporosis

Cita:Cells 2024 Apr 20; 13 (8)

Autor/es:Ivanova, Margarita M (a)
Dao, Julia (b)

institución:(a) Lysosomal and Rare Disorders Research and Treatment Center, Fairfax, VA 22030, USA.
(b) Lysosomal and Rare Disorders Research and Treatment Center, Fairfax, VA 22030, USA.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3390/cells13080716

Efficacy and safety of aripiprazole or bupropion augmentation and switching in patients with treatment-resistant depression or major depressive disorder

Efficacy and safety of aripiprazole or bupropion augmentation and switching in patients with treatment-resistant depression or major depressive disorder

Fuente:Plos One

Tipo de trabajo:Revisión sistemática

Extracto: A-ARI may be a better comprehensive antidepressant treatment strategy than A-BUP or S-BUP for patients with TRD or MDD. More large-scale, multi-center, double-blind RCTs are needed to further evaluated the efficacy and safety of aripiprazole or bupropion augmentation and switching treatment strategies.

Cita:PLoS One 2024; 19 (4) : e0299020.

Autor/es:Ji, Mengjia (a)
Feng, Junfei (b)

institución:(a) Department of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Jinan, Shandong Province, China.
(b) Department of Traditional Chinese Medicine, Shandong Wendeng Osteopath Hospital, Weihai, Shandong Province, China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1371/journal.pone.0299020

Pharmacological prevention of bone loss and fractures following solid organ transplantations

Fuente:Plos One

Tipo de trabajo:Revisión sistemática

Extracto: The findings of the NMA will be disseminated in a peer-reviewed journal.

Cita:PLoS One 2024; 19 (4) : e0302566.

Autor/es:Deng, Jiawen (a)
Moskalyk, Myron (b)

institución:(a) Faculty of Health Sciences, McMaster University, Hamilton, ON, Canada.
(b) Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1371/journal.pone.0302566

Overcoming barriers to equality, diversity, inclusivity, and sense of belonging in healthcare education: the Underrepresented Groups' Experiences in Osteopathic Training (UrGEnT) mixed methods study.

Overcoming barriers to equality, diversity, inclusivity, and sense of belonging in healthcare education: the Underrepresented Groups' Experiences in Osteopathic Training (UrGEnT) mixed methods study.

Fuente:Bmc Medical Education

Extracto: Our findings confirm conclusions from other institutions that staff education is urgently needed to create and maintain equitable, inclusive environments in osteopathic educational institutions in the UK to support all students, particularly those from underrepresented groups. Institutional EDI processes and policies also need to be clarified or modified to ensure their usefulness, accessibility, and implementation.

Claves:Disability, Equity diversity and inclusion, Ethnic minorities, LGBTQIA+, Oppressed, Osteopathic undergraduate education, Social Justice, Transformative action research, Underrepresented, Women

Cita:BMC Med Educ 2024 Apr 26; 24 (1) : 468.

Autor/es:Draper-Rodi, Jerry (a)
Abbey, Hilary (b)

institución:(a) University College of Osteopathy, 275 Borough High Street, SE1 1JE, London, UK. jerry.draper-rodi@uco.ac.uk.
(b) National Council for Osteopathic Research, 275 Borough High Street, SE1 1JE, London, UK. jerry.draper-rodi@uco.ac.uk.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12909-024-05404-3

Assessing Regional Weather's Impact on Spinal Cord Injury Survivors, Caregivers, and General Public in Miami, Florida.

Assessing Regional Weather's Impact on Spinal Cord Injury Survivors, Caregivers, and General Public in Miami, Florida.

Fuente:International Journal of Environmental Research and Public Health

Extracto: Continued and more comprehensive research is needed to characterize the barriers that vulnerable populations face during weather events.

Claves:climate change, disability care, environmental health, extreme weather events, knowledge-attitudes-behaviors, risk communication

Cita:Int J Environ Res Public Health 2024 Mar 22; 21 (4)

Autor/es:Bass, Danielle Hildegard (a)
Ghamasaee, Pardis (b)

institución:(a) Department of Neurology, Miller School of Medicine, University of Miami, Miami, FL 33136, USA.
(b) Department of Public Health Sciences, Miller School of Medicine, University of Miami, Miami, FL 33136, USA.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3390/ijerph21040382

Feasibility and Preliminary Efficacy of American Elderberry Juice for Improving Cognition and Inflammation in Patients with Mild Cognitive Impairment.

Feasibility and Preliminary Efficacy of American Elderberry Juice for Improving Cognition and Inflammation in Patients with Mild Cognitive Impairment.

Fuente:International Journal of Molecular Sciences

Extracto: These promising findings support the need for larger, more definitive prospective studies with longer follow-ups to better understand mechanisms of action and the clinical utility of elderberries for potentially mitigating cognitive decline.

Claves:cognition, elderberry, inflammatory, mild cognitive impairment, proteomics, sambucus

Cita:Int J Mol Sci 2024 Apr 15; 25 (8)

Autor/es:Curtis, Ashley F (a)
Musich, Madison (b)

institución:(a) College of Nursing, University of South Florida, Tampa, FL 33620, USA.
(b) Department of Psychological Sciences, University of Missouri, Columbia, MO 65201, USA.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3390/ijms25084352

Potential probiotic Lactobacillus delbrueckii subsp. lactis KUMS-Y33 suppresses adipogenesis and promotes osteogenesis in human adipose-derived mesenchymal stem cell.

Potential probiotic Lactobacillus delbrueckii subsp. lactis KUMS-Y33 suppresses adipogenesis and promotes osteogenesis in human adipose-derived mesenchymal stem cell.

Fuente:Scientific Reports

Extracto: According to the results of the present study, the probiotic extract inhibits adipogenesis and significantly increases osteogenesis, suggesting a positive role in the prevention and treatment of osteoporosis and opening a new aspect for future in-vivo study.

Claves:Lactobacillus, Adipogenesis, Human Adipose-derived stem cells, Osteogenesis, Probiotics

Cita:Sci Rep 2024 Apr 27; 14 (1) : 9689.

Autor/es:Goudarzi, Farjam (a)
Kiani, Amir (b)

institución:(a) Regenerative Medicine Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran.
(b) Regenerative Medicine Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1038/s41598-024-60061-2

Association of serum sclerostin levels with marrow adiposity in postmenopausal women with glucocorticoid-induced osteoporosis.

Association of serum sclerostin levels with marrow adiposity in postmenopausal women with glucocorticoid-induced osteoporosis.

Fuente:Bmc Endocrine Disorders

Extracto: Circulating sclerostin levels exhibited a noteworthy association with marrow adiposity in postmenopausal women grappling with GIO.

Claves:Glucocorticoid-induced osteoporosis, Magnetic resonance spectroscopy, Marrow adiposity, Sclerostin

Cita:BMC Endocr Disord 2024 Apr 28; 24 (1) : 55.

Autor/es:Li, Wei (a)
Wang, Wei (b)

institución:(a) Department of Radiology, Pudong New Area, Shanghai University of Medicine & Health Sciences Affiliated Zhoupu Hospital, No. 1500 Zhouyuan Road, Shanghai, 201318, China.
(b) Department of Radiology, Pudong New Area, Shanghai University of Medicine & Health Sciences Affiliated Zhoupu Hospital, No. 1500 Zhouyuan Road, Shanghai, 201318, China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12902-024-01591-8

Hepatocellular carcinoma and musculoskeletal system

Hepatocellular carcinoma and musculoskeletal system

Fuente:World Journal of Gastroenterology

Tipo de trabajo:Revisión

Extracto: Further research into the mechanisms and treatment options for musculoskeletal complications is warranted to enhance our understanding and clinical management of this aspect of HCC.

Claves:Bone fragility, Bone metastases, Hepatocellular carcinoma, Osteopenia, Osteoporosis, Sarcopenia

Cita:World J Gastroenterol 2024 Apr 21; 30 (15) : 2109-2117.

Autor/es:Jadzic, Jelena (a)
Djonic, Danijela (b)

institución:(a) Center of Bone Biology, Faculty of Medicine, University of Belgrade, Belgrade 11000, Serbia.
(b) Center of Bone Biology, Faculty of Medicine, University of Belgrade, Belgrade 11000, Serbia. ddjonic@yahoo.com.

Conflicto:Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.

Formato:Informe impreso

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.3748/wjg.v30.i15.2109

Electrophysiological phenotyping of left ventricular noncompaction cardiomyopathy in pediatric populations

Electrophysiological phenotyping of left ventricular noncompaction cardiomyopathy in pediatric populations

Fuente:Physiological Reports

Tipo de trabajo:Revisión sistemática

Extracto: While LVNC in pediatric populations may not always present as acute clinical cases, further investigation into the electrophysiology of the disease supports the need for further evaluation and risk stratification for patients with suspected LVNC and/or ventricular arrhythmia.

Claves:arrhythmia, cardiomyopathy, electrocardiogram, fetal myocardium, honeycomb myocardium, hypertrabeculation, left ventricular noncompaction, noncompaction myocardium, pediatric, spongy myocardium

Cita:Physiol Rep 2024 May; 12 (9) : e16029.

Autor/es:Fitzsimons, Lindsey A (a)
Kneeland-Barber, Delanie M (b)

institución:(a) Department of Biomedical Sciences, College of Osteopathic Medicine, University of New England, Biddeford, Maine, USA.
(b) Department of Biomedical Sciences, College of Osteopathic Medicine, University of New England, Biddeford, Maine, USA.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe impreso

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.14814/phy2.16029

The impact of hydroxyapatite crystal structures and protein interactions on bone's mechanical properties.

The impact of hydroxyapatite crystal structures and protein interactions on bone's mechanical properties.

Fuente:Scientific Reports

Extracto: By uncovering the interface mechanical behavior between HAP and osteopontin peptides, this article offers valuable theoretical insights for the construction and biomimetic design of biocomposites.

Cita:Sci Rep 2024 Apr 29; 14 (1) : 9786.

Autor/es:Sun, Yadi (a)
Wang, Yan (b)

institución:(a) Tianjin Hospital, Tianjin University, Tianjin, 300211, People's Republic of China.
(b) Tianjin Orthopedic Institute, Tianjin, 300050, People's Republic of China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1038/s41598-024-60701-7

Rare complication of rheumatoid arthritis: Charcot Neuro-osteoarthropathy.

Rare complication of rheumatoid arthritis: Charcot Neuro-osteoarthropathy.

Fuente:Bmc Musculoskeletal Disorders

Tipo de trabajo:Caso clínico

Extracto: Rheumatoid arthritis complicated with Charcot's joint is rare. Clinically, patients with rheumatoid diseases should not ignore Charcot's joint complications because of rareness. Early blood inflammatory markers, neuro electrophysiology, and imaging MRI of rheumatoid CN are of great significance for the diagnosis of this mild or early neurovascular inflammation. Early diagnosis and treatment are helpful to prevent further joint injury. The clinical diagnosis, treatment, and molecular mechanism of osteolysis in RA and peripheral sensory nerve injury remain to be further revealed.

Claves:Case report, Charcot Neuro-osteoarthropathy, Molecular mechanism;diagnosis, Rheumatoid arthritis, Treatment

Cita:BMC Musculoskelet Disord 2024 Apr 29; 25 (1) : 340.

Autor/es:Luo, Zhiyuan (a)
Ding, Xinxiang (b)

institución:(a) The Eighth Clinical Medical College of Guangzhou University of Chinese Medicine, Foshan, Guangdong, China.
(b) The Eighth Clinical Medical College of Guangzhou University of Chinese Medicine, Foshan, Guangdong, China.

Conflicto:There is no conflict of interest with any institution or author in this work. This manuscript has not yet received funding.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12891-024-07424-y