The Dutch multidisciplinary guideline osteoporosis and fracture prevention, taking a local guideline to the international arena.

The Dutch multidisciplinary guideline osteoporosis and fracture prevention, taking a local guideline to the international arena.

Fuente:Archives of Osteoporosis

Tipo de trabajo:Consenso

Extracto: In our new multidisciplinary guideline osteoporosis and fracture prevention, we developed 5 "relatively new statements" that are all a crucial step forward in the optimization of diagnosis and treatment for fracture prevention. We also developed 5 flowcharts, and we suppose that this may be helpful for individual doctors and their patients in daily practice and may facilitate implementation.

Claves:Fracture prevention, Multidisciplinary guideline, Osteoporosis

Cita:Arch Osteoporos 2024 Apr 2; 19 (1) : 23.

Autor/es:van den Bergh, J P (a)
Geusens, P (b)

institución:(a) Department of Internal Medicine, VieCuri Medical Center, Venlo, the Netherlands. joop.vandenbergh@maastrichtuniversity.nl.
(b) Department of Internal Medicine, Maastricht University Medical Center, Maastricht, the Netherlands. joop.vandenbergh@maastrichtuniversity.nl.

Conflicto:JvdB: lecture fees from Amgen, UCB; PG: lecture fees/advisory boards Sanzoz, MSD, Galapagos, Fresenius, Celltrion, Amgen; NMA-D: lecture fees from Amgen, UCB. Research funding Takeda, Kyowa Kirin, UCB; GdK: lecture fees from Amgen; HW: lecture fees from Amgen, UCB; WFL: lecture fees/advisory boards from Amgen, UCB, Pfizer, Galapagos; HvdB, PE, MO, MCZ, GdK no conflict of interest.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1007/s11657-024-01378-3

Prediction model for spinal cord injury in spinal tuberculosis patients using multiple machine learning algorithms: a multicentric study.

Prediction model for spinal cord injury in spinal tuberculosis patients using multiple machine learning algorithms: a multicentric study.

Fuente:Scientific Reports

Extracto: The RF predictive model provides an efficient and swift approach for predicting SCI in STB patients.

Claves:Machine learning, Model deployment, Model interpretation, Predictive model, Spinal cord injury, Spinal tuberculosis

Cita:Sci Rep 2024 Apr 2; 14 (1) : 7691.

Autor/es:Feng, Sitan (a)
Wang, Shujiang (b)

institución:(a) Department of Spine and Osteopathy Ward, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, People's Republic of China.
(b) Department of Outpatient, General Hospital of Eastern Theater Command, Nanjing, Jiangsu, People's Republic of China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1038/s41598-024-56711-0

Blood cell count-derived inflammation indices as predictors of the osteoporotic risk of postmenopausal women.

Blood cell count-derived inflammation indices as predictors of the osteoporotic risk of postmenopausal women.

Fuente:European Review For Medical and Pharmacological Sciences

Extracto: High levels of SII, PLR, NLR, and MLR were associated with a high OP risk. In particular, NLR > 2.02 strongly predicted the risk of OP, thereby representing a valuable and convenient inflammatory marker of the OP risk.

Cita:Eur Rev Med Pharmacol Sci 2024 Mar; 28 (6) : 2207-2216.

Autor/es:Zhang, X-J (a)
Zhao, H (b)

institución:Zhang, X-J (a)
Zhao, H (b)

Formato:Informe impreso

Idioma:Inglés

País de fuente:Italia

Sitio web:http://dx.doi.org/10.26355/eurrev_202403_35725

Causal relationship between circulating inflammatory factors and osteoporosis: a bidirectional Mendelian randomization study.

Fuente:European Review For Medical and Pharmacological Sciences

Tipo de trabajo:Metanálisis

Extracto: This study demonstrated the pathogenic role of circulating inflammatory modulators in OP using bidirectional MR analysis. This further deepens the understanding of OP pathogenesis and provides new ideas for therapeutic intervention in OP.

Cita:Eur Rev Med Pharmacol Sci 2024 Mar; 28 (6) : 2237-2249.

Autor/es:Yi, K-J (a)
Kang, R-M (b)

institución:Yi, K-J (a)
Kang, R-M (b)

Formato:Informe impreso

Idioma:Inglés

País de fuente:Italia

Sitio web:http://dx.doi.org/10.26355/eurrev_202403_35728

Surgical management of lower limb radiculopathy following acute singe-level osteoporotic vertebral fracture of lower lumbar spine in geriatric patient: a retrospective study.

Surgical management of lower limb radiculopathy following acute singe-level osteoporotic vertebral fracture of lower lumbar spine in geriatric patient: a retrospective study.

Fuente:Bmc Musculoskeletal Disorders

Extracto: Patients with OVFs in the IEP are predisposed to suffer from radiculopathy of the lower limb. PKP alone or in combination with other minimally invasive surgical strategies is safe and effective in treating stable fractures. Additionally, aggressive surgical intervention should be considered in patients with unstable fractures or severe foraminal encroachment.

Claves:Foraminal stenosis, Inferior endplate fracture, Osteoporotic vertebral fracture, Percutaneous kyphoplasty, Radiculopathy

Cita:BMC Musculoskelet Disord 2024 Apr 3; 25 (1) : 262.

Autor/es:Zhang, Yao (a)
Lu, Yuzheng (b)

institución:(a) Department of Spinal Surgery, Beijing Shijitan Hospital, Capital Medical University, No. 10, tieyi road, Yangfangdian, Haidian district, Beijing, 100038, People's Republic of China.
(b) Department of Spinal Surgery, Beijing Shijitan Hospital, Capital Medical University, No. 10, tieyi road, Yangfangdian, Haidian district, Beijing, 100038, People's Republic of China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12891-024-07314-3

Association of coffee intake with bone mineral density: a Mendelian randomization study.

Association of coffee intake with bone mineral density: a Mendelian randomization study.

Fuente:Frontiers in Endocrinology

Tipo de trabajo:Guía

Extracto: The results of the present study provide genetic evidence for the idea that coffee intake is beneficial for bone density. Further studies are needed to reveal the biological mechanisms and offer solid support for clinical guidelines on osteoporosis prevention.

Claves:Mendelian randomization, beneficial, bone mineral density, causal effect, coffee intake

Cita:Front Endocrinol (Lausanne) 2024; 15 : 1328748.

Autor/es:Ye, Yang (a)
Zhong, Rui (b)

institución:(a) Department of Spinal Surgery, Affiliated Sports Hospital of Chengdu Sport University, Chengdu, China.
(b) Department of Spinal Surgery, Affiliated Sports Hospital of Chengdu Sport University, Chengdu, China.

Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3389/fendo.2024.1328748

GBA1 as a risk gene for osteoporosis in the specific populations and its role in the development of Gaucher disease.

GBA1 as a risk gene for osteoporosis in the specific populations and its role in the development of Gaucher disease.

Fuente:Orphanet Journal of Rare Diseases

Extracto: Elevated ER stress and inflammasome activation are indicative of osteoporosis development, suggesting the need for clinical monitoring of patients with GD. Furthermore, disease-associated variant in the GBA1 gene may constitute a risk factor predisposing specific populations to osteoporosis.

Claves:Endoplasmic reticulum stress, GBA1, Gaucher disease, Inflammasome, Osteoclastogenesis, Osteoporosis

Cita:Orphanet J Rare Dis 2024 Apr 4; 19 (1) : 144.

Autor/es:Wang, Chung-Hsing (a)
Huang, Yu-Nan (b)

institución:(a) Division of Genetics and Metabolism, Children's Hospital of China Medical University, Taichung, Taiwan.
(b) School of Medicine, China Medical University, Taichung, Taiwan.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s13023-024-03132-x

Construction and verification of risk prediction model of osteoporotic fractures in patients with osteoporosis in China.

Construction and verification of risk prediction model of osteoporotic fractures in patients with osteoporosis in China.

Fuente:Frontiers in Public Health

Extracto: In this study, a OPF risk prediction model is established and its prediction efficiency is verified, which can help identify the high fracture risk subgroup of osteoporosis patients in order to choose stronger intervention measures and management.

Claves:China, OPF, osteoporosis, prediction model, retrospective cohort study

Cita:Front Public Health 2024; 12 : 1380218.

Autor/es:Xia, Peifang (a)
Jiang, Yingqing (b)

institución:(a) Department of Orthopedic Surgery, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China.
(b) Department of Orthopedic Surgery, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China.

Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3389/fpubh.2024.1380218

Relationship between blood cadmium levels and bone mineral density in adults: a cross-sectional study.

Relationship between blood cadmium levels and bone mineral density in adults: a cross-sectional study.

Fuente:Frontiers in Endocrinology

Extracto: Our findings demonstrated a significant negative association between blood cadmium levels and bone mineral density in a population of U.S. adults.

Claves:NHANES, adults, blood cadmium, bone mineral density, osteoporosis

Cita:Front Endocrinol (Lausanne) 2024; 15 : 1354577.

Autor/es:Lei, Yi (a)
Guo, Meiqian (b)

institución:(a) Department of Nephrology, The Affiliated Huai'an Hospital of Xuzhou Medical University and Huai'an Second People's Hospital, Huai'an, China.
(b) Department of Clinical Laboratory, The Affiliated Huai'an Hospital of Xuzhou Medical University and Huai'an Second People's Hospital, Huai'an, China.

Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3389/fendo.2024.1354577

Sex- and Age-Specific Prevalence of Osteopenia and Osteoporosis: Sampling Survey.

Sex- and Age-Specific Prevalence of Osteopenia and Osteoporosis: Sampling Survey.

Fuente:Jmir Public Health and Surveillance

Extracto: Our data imply that as people age, osteopenia and osteoporosis are more common in females than in males, particularly in postmenopausal females than in premenopausal females, and bone mineral density significantly affects the prevalence of chronic diseases. These findings offer information that can be applied to intervention programs meant to prevent or lessen the burden of osteoporosis in China.

Claves:cross-sectional study, osteopenia, osteoporosis, prevalence, quantitative ultrasound

Cita:JMIR Public Health Surveill 2024 Apr 5; 10 : e48947.

Autor/es:Fan, Yao (a)
Li, Qun (b)

institución:(a) Division of Clinical Epidemiology, Affiliated Geriatric Hospital of Nanjing Medical University, Nanjing, China.
(b) Department of Nutrition, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Canadá

Sitio web:http://dx.doi.org/10.2196/48947

Detection of hypophosphatasia in hospitalised adults in rheumatology and internal medicine departments

Detection of hypophosphatasia in hospitalised adults in rheumatology and internal medicine departments

Fuente:Rmd Open

Tipo de trabajo:Estudio multicéntrico

Extracto: In this 10-year retrospective study, 0.32% of adult patients hospitalised in the rheumatology and internal medicine departments had persistently low serum ALP, and among them, 6% had genetically proven HPP. Reported hypophosphatasaemia represented only 3.6% of hospitalised patients.

Claves:bone density, osteoporosis, prevalence

Cita:RMD Open 2024 Apr 4; 10 (2)

Autor/es:Larid, Guillaume (a)
Vix, Justine (b)

institución:(a) Department of Rheumatology, CHU Poitiers, Poitiers, France guillaume.larid@chu-poitiers.fr.
(b) LITEC, Poitiers University, Poitiers, France.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1136/rmdopen-2024-004316

Trajectories of depressive symptom and its association with air pollution

Trajectories of depressive symptom and its association with air pollution

Fuente:Bmc Geriatrics

Tipo de trabajo:Estudio de cohortes

Extracto: In this study, we found that a late increase in depressive symptoms was the predominant trend in older Chinese people in Hong Kong. Poorer HRQOL was predictive of less favorable trajectories of depressive symptoms. Ambient air pollution was associated with depressive symptoms. This novel observation strengthens the epidemiological evidence of longitudinal changes in depressive symptoms and associations with late-life exposure to air pollution.

Claves:Air pollutants, Depressive symptoms, Longitudinal trajectory, Older adults

Cita:BMC Geriatr 2024 Apr 5; 24 (1) : 318.

Autor/es:Zhao, Yinan (a)
Liu, Qingcai (b)

institución:(a) Xiangya School of Nursing, Central South University, Changsha, Hunan Province, China.
(b) Xiangya School of Nursing, Central South University, Changsha, Hunan Province, China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12877-024-04731-w

Improved cardiac auscultation competency interweaving visual, auditory, and tactile stimuli: a preliminary study.

Fuente:International Journal of Medical Education

Tipo de trabajo:Estudio aleatorizado y controlado

Extracto: These findings suggest the incorporation of multisensory stimuli significantly improves cardiac auscultation competency. Given its cost-effectiveness and simplicity, this approach offers a viable alternative to more expensive simulation technologies like the Harvey simulator, particularly in settings with limited resources. Consequently, this teaching modality holds promise for global applicability, addressing the worldwide deterioration in cardiac auscultation skills and potentially leading to better patient outcomes. Future studies should broaden the sample size, span multiple institutions, and investigate long-term retention rates.

Claves:cardiac auscultation, competency, education, simulation

Cita:Int J Med Educ 2024 Apr 5; 15 : 37-43.

Autor/es:Patrizio, Harrison A (a)
Phyu, Riley (b)

institución:(a) Rowan University School of Osteopathic Medicine, USA.
(b) Rowan University School of Osteopathic Medicine, USA.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.5116/ijme.6607.27a6

Genotyping Plasmodium falciparum gametocytes using amplicon deep sequencing.

Genotyping Plasmodium falciparum gametocytes using amplicon deep sequencing.

Fuente:Malaria Journal

Extracto: A region of the pfs230 gene was identified as a marker to genotype P. falciparum gametocytes. Amplicon deep sequencing of this marker can be used to estimate the number and relative frequency of parasite clones among mature gametocytes within P. falciparum infections. This gametocyte genotyping marker will be an important tool for studies aimed at understanding dynamics of gametocyte production in polyclonal P. falciparum infections.

Claves:Plasmodium falciparum, Amplicon deep sequencing, Complexity of infection, Gametocyte genotyping, Malaria transmission

Cita:Malar J 2024 Apr 6; 23 (1) : 96.

Autor/es:Vareta, Jimmy (a)
Horstman, Natalie A (b)

institución:(a) Center for Vaccine Development and Global Health, University of Maryland School of Medicine, Baltimore, MD, USA.
(b) Center for Vaccine Development and Global Health, University of Maryland School of Medicine, Baltimore, MD, USA.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12936-024-04920-3

Association of cardiovascular disease prevalence with BMD and fracture in men with T2DM.

Association of cardiovascular disease prevalence with BMD and fracture in men with T2DM.

Fuente:Journal of Diabetes

Extracto: The prevalence of CVD was inversely correlated with BMD levels in men with T2DM, particularly at the FN. We hypothesized that monitoring FN-BMD and early intervention would help reduce CVD risk in men with T2DM, especially those with hypertension.

Claves:bone mineral density, cardiovascular disease, type 2 diabetes mellitus

Cita:J Diabetes 2024 Apr; 16 (4) : e13530.

Autor/es:Kong, Xiao-Ke (a)
Xie, Rui (b)

institución:(a) Department of Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
(b) Shanghai National Clinical Research Center for Metabolic Diseases, Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission of the PR China, Shanghai Key Laboratory for Endocrine Tumor, State Key Laboratory of Medical Genomics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Conflicto:Jian‐min Liu is an Editorial Board member of the Journal of Diabetes and a coauthor of this article. To minimize bias, he was excluded from all editorial decision‐making related to the acceptance of this article for publication.

Formato:Informe impreso

Idioma:Inglés

País de fuente:Australia

Sitio web:http://dx.doi.org/10.1111/1753-0407.13530

Development and experimental validation of an energy metabolism-related gene signature for diagnosing of osteoporosis.

Development and experimental validation of an energy metabolism-related gene signature for diagnosing of osteoporosis.

Fuente:Scientific Reports

Extracto: Furthermore, the DANCR/hsa-miR-23b-3p/B4GALT4 axis might provide novel molecular insights into the process of osteoporosis development.

Claves:Energy metabolism, Immune microenvironment, Osteoporosis, Risk model

Cita:Sci Rep 2024 Apr 8; 14 (1) : 8153.

Autor/es:Lu, Yao (a)
Wen, Wen (b)

institución:(a) Department of Orthopaedics, Honghui Hospital, Xi'an Jiaotong University, 555 Youyi East Road, Xi'an, 710054, Shaan'xi Province, China.
(b) Department of Orthopedics, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1038/s41598-024-59062-y

Does post acute care reduce the mortality of octogenarian and nonagenarian patients undergoing hip fracture surgery?

Does post acute care reduce the mortality of octogenarian and nonagenarian patients undergoing hip fracture surgery?

Fuente:Bmc Geriatrics

Extracto: PAC is associated with a lower rate of mortality and complications such as urinary tract infection, bed sore, and pneumonia in octogenarian and nonagenarian patients with hip fragility fracture.

Claves:Fragile fracture, Hip fracture, Mortality, Osteoporosis, Post-acute-care

Cita:BMC Geriatr 2024 Apr 8; 24 (1) : 322.

Autor/es:Chiang, Yu-Wei (a)
Chang, Yu-Jun (b)

institución:(a) Department of Orthopedics, Changhua Christian Hospital, No. 135, Nanxiao St., Changua City, Changhua County, 500054, Taiwan R.O.C.
(b) Big Data Center, Changhua Christian Hospital, No. 135, Nanxiao St., Changua City, Changhua County, 500054, Taiwan R.O.C.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12877-024-04936-z

Current perspectives on the multiple roles of osteoclasts: Mechanisms of osteoclast-osteoblast communication and potential clinical implications.

Fuente:Elife

Extracto: This comprehensive review provides insights into our evolving understanding of the osteoclast function, highlights the significance of clastokines in bone remodeling, and explores their potential as treatments for bone diseases suggesting future directions for the field.

Claves:bone homeostasis, clastokines, communication, coupling, medicine, osteoblasts, osteoclasts

Cita:Elife 2024 Apr 9; 13

Autor/es:Daponte, Valentina (a)
Henke, Katrin (b)

institución:(a) Department of Orthopaedics, Emory University School of Medicine, Atlanta, United States.
(b) VA Medical Center, Atlanta, United States.

Conflicto:VD, KH, HD No competing interests declared

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.7554/eLife.95083

Bone evaluation study-2: update on the epidemiology of osteoporosis in Germany.

Bone evaluation study-2: update on the epidemiology of osteoporosis in Germany.

Fuente:Archives of Osteoporosis

Extracto: Germany has a high prevalence of osteoporosis. Only a small portion of individuals who may require osteoporosis-specific treatment actually receive it.

Claves:Care gap, Fracture, Osteoporosis, Prevalence, Secondary analysis

Cita:Arch Osteoporos 2024 Apr 9; 19 (1) : 26.

Autor/es:Peyman, Hadji (a)
Elizabeth, Esterberg (b)

institución:(a) Frankfurter Hormon- Und Osteoporosezentrum, Frankfurt Am Main, Germany.
(b) Philipps-Universität Marburg, Marburg, Germany.

Conflicto:This manuscript was created with the assistance of a medical writer, a graphic designer and two editors. These services were funded by Amgen, Germany. PH received fees for consulting and speaking from Amgen Ltd, Elli Lilly, Gedeon Richter, Hexal, Stada, Theramex and UCB. EE is employed by RTI Health Solutions, an independent non-profit organization that received financial support from Amgen... to conduct this study. DO is an employee of InGef, which received financial support from RTI Health Solutions to conduct this study. RB is an employee of Amgen and holds stocks in Amgen Ltd.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1007/s11657-024-01380-9

Diagnostic Delay of Celiac Disease in Childhood.

Diagnostic Delay of Celiac Disease in Childhood.

Fuente:Jama Network Open

Extracto: AND RELEVANCE: In this cross-sectional study of pediatric CD, the diagnostic delay was rather short. Some factors associated with risk for longer diagnostic delay and misdiagnosis emerged, and these should be addressed in future studies.

Cita:JAMA Netw Open 2024 Apr 1; 7 (4) : e245671.

Autor/es:Bianchi, Paola Ilaria (a)
Lenti, Marco Vincenzo (b)

institución:(a) First Department of Internal Medicine, Istituto di Ricovero e Cura a Carattere Scientifico Fondazione Policlinico San Matteo, Pavia, Italy.
(b) First Department of Internal Medicine, Istituto di Ricovero e Cura a Carattere Scientifico Fondazione Policlinico San Matteo, Pavia, Italy.

Conflicto:Conflict of Interest Disclosures: Dr Staiano reported receiving consultation fees from Aboca Consultancy, Novalac Consultancy, and Pileje Consultancy outside the submitted work. No other disclosures were reported.

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1001/jamanetworkopen.2024.5671