Intravenous infusion of dexmedetomidine during the surgery to prevent postoperative delirium and postoperative cognitive dysfunction undergoing non-cardiac surgery

Intravenous infusion of dexmedetomidine during the surgery to prevent postoperative delirium and postoperative cognitive dysfunction undergoing non-cardiac surgery

Fuente:European Journal of Medical Research

Tipo de trabajo:Metanálisis

Extracto: Compared with other interventions, intravenous dexmedetomidine infusion during non-cardiac and non-neurosurgical procedures may significantly reduce the risk of postoperative delirium and cognitive dysfunction. The results of subgroup analysis reveal a consistent preventive effect on postoperative delirium in both general and non-general anaesthesia groups. Meanwhile, continuous infusion during general anaesthesia was more effective in reducing the risk of cognitive dysfunction. Despite such findings, hypotension and bradycardia were more frequent in patients who received dexmedetomidine during surgery.

Claves:Dexmedetomidine, Non-cardiac surgery and non-neurosurgery, Postoperative cognitive dysfunction, Postoperative delirium

Cita:Eur J Med Res 2024 Apr 18; 29 (1) : 239.

Autor/es:Wang, Di (a)
Liu, Zhi (b)

institución:(a) Department of Anaesthesiology, Dalian Municipal Central Hospital Affiliated to Dalian University of Technology, Dalian, Liaoning, China.
(b) Dalian Medical University, Dalian, China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s40001-024-01838-z

"Quality of Life in Epidermolysis Bullosa" and "Epidermolysis Bullosa Burden of Disease": Italian translation, cultural adaptation, and pilot testing of two disease-specific questionnaires.

"Quality of Life in Epidermolysis Bullosa" and "Epidermolysis Bullosa Burden of Disease": Italian translation, cultural adaptation, and pilot testing of two disease-specific questionnaires.

Fuente:Italian Journal of Pediatrics

Tipo de trabajo:Guía

Extracto: The Italian versions of the QOLEB and EB-BoD provide valuable tools in everyday clinical practice of reference centers, and they allow the participation in multicenter international real-life observational studies as well as in controlled clinical trials. They enable the identification of disease-specific psychological and socioeconomic challenges for EB patients and their families, guiding targeted interventions to ensure appropriate and timely care.

Claves:Dermatology, Dystrophic epidermolysis bullosa, Epidermolysis bullosa simplex, Family burden, Inherited epidermolysis bullosa, Junctional epidermolysis bullosa, Kindler epidermolysis bullosa, Quality of life

Cita:Ital J Pediatr 2024 Apr 19; 50 (1) : 76.

Autor/es:Hachem, May El (a)
Diociaiuti, Andrea (b)

institución:(a) Dermatology Unit and Genodermatosis Research Unit, Translational Paediatrics and Clinical Genetics Research Division, Bambino Gesù Children's Hospital, IRCCS, Piazza Sant'Onofrio 4, 00165, Rome, Italy.
(b) Dermatology Unit and Genodermatosis Research Unit, Translational Paediatrics and Clinical Genetics Research Division, Bambino Gesù Children's Hospital, IRCCS, Piazza Sant'Onofrio 4, 00165, Rome, Italy. andrea.diociaiuti@opbg.net.

Conflicto:He authors declare that they have no competing interests.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s13052-024-01657-2

Progression of the FIB-4 index among patients with chronic HCV infection and early liver disease.

Progression of the FIB-4 index among patients with chronic HCV infection and early liver disease.

Fuente:Bmj Open Gastroenterology

Extracto: The rate of advanced liver disease is high among chronic HCV-infected patients with early disease at time of diagnosis, among whom liver disease progression accelerated over time. These results emphasise the need to overcome any limitations with respect to diagnosing and treating all patients with chronic HCV across the globe.

Claves:CLINICAL DECISION MAKING, HEPATIC FIBROSIS, HEPATITIS C

Cita:BMJ Open Gastroenterol 2023 Dec 7; 10 (1)

Autor/es:Krassenburg, Lisette A P (a)
Maan, Raoel (b)

institución:(a) Department of Gastroenterology & Hepatology, Erasmus Medical Center, Rotterdam, The Netherlands.
(b) Francis Family Liver Clinic, Toronto Centre for Liver Disease, Toronto, Ontario, Canada.

Conflicto:Competing interests: LK, NSE, CW, SvH, OC, JV and RAdM report no conflict of interest. RM received financial compensation for consultancy from AbbVie. AP is an employee of Merck & Co. RJdK declares that the Erasmus University Medical Center, on behalf of RJdK, received honoraria for consulting/speaking from Gilead, Janssen-Cilag, Bristol-Myers Squibb (BMS), AbbVie, MSD, Roche and Norgine, and received... research grants from Gilead, Janssen-Cilag, BMS and Roche. BEH has consulted for and received grant/research support from Intercept Pharmaceuticals. SZ reports consultancies for AbbVie, BMS, Gilead, Janssen and Merck. TV has received grants from Gilead Sciences and BMS; is a consultant for Janssen Pharmaceuticals, Gilead Sciences, AbbVie and BMS; and a sponsored lecturer for W L Gore, Gilead Sciences, BMS and AbbVie. HLAJ has served as consultant for and has received grants from AbbVie, Arbutus, BMS, Enyo, Gilead Sciences, Janssen, Medimmune, Merck, Roche, Vir Biotechnology and Viroclinics. JJF has consulted for Abbott, AbbVie, Gilead, Enanta and Roche; and has received grant/research support from AbbVie, Eiger, Gilead, Janssen and Wako/Fujifilm. AJvdM received financial compensation for lecture activities for Zambon and research funding from Gilead, MSD, AbbVie and Zambon.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1136/bmjgast-2023-001209

Immunoglobulin-like transcript 2 as an impaired anti-tumor cytotoxicity marker of natural killer cells in patients with hepatocellular carcinoma.

Immunoglobulin-like transcript 2 as an impaired anti-tumor cytotoxicity marker of natural killer cells in patients with hepatocellular carcinoma.

Fuente:Frontiers in Immunology

Extracto: In HCC patients, ILT2 is a signature molecule for cancerous CD56(dim) NK cells with impaired cytolytic capacity. The MIF-CXCR4 interaction is associated with ILT2 induction on CD56(dim) NK cells and ILT2 serves as a target for functional NK cell restoration.

Claves:ADCC, HCC, HLA-G, ILT2, MIF, NK cells

Cita:Front Immunol 2024; 15 : 1389411.

Autor/es:Sakata, Toshihiro (a)
Yoshio, Sachiyo (b)

institución:(a) Department of Liver Diseases, The Research Center for Hepatitis and Immunology, National Center for Global Health and Medicine, Chiba, Japan.
(b) Department of Gastoenterological Surgery I, Hokkaido University Graduate School of Medicine, Hokkaido, Japan.

Conflicto:SY has received a lecture fee from Gilead Sciences. TI has received lecture fees from Chugai Pharmaceutical Co., Ltd. and AstraZeneca, and a research grant from Chugai Pharmaceutical Co., Ltd. HT has received lecture fees from Gilead Sciences, AbbVie, Eisai, Fujifilm WAKO, Terumo, Kowa, Takeda and AstraZeneca. TKK has received lecture fees from Janssen Pharmaceutical, Taisho Pharmaceutical, Kowa Company, Otsuka... Pharmaceutical, Eisai, ASKA Pharmaceutical, AbbVie, and EA Pharma. AT has received a research grant from Ono Pharmaceutical Co. TTK has received lecture fees from Gilead Sciences and AbbVie. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. The author(s) declared that they were an editorial board member of Frontiers, at the time of submission. This had no impact on the peer review process and the final decision.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3389/fimmu.2024.1389411

Evaluating the causal association between bronchiectasis and different types of inflammatory bowel disease: a two-sample Mendelian randomization study.

Fuente:Frontiers in Immunology

Extracto: This MR analysis demonstrated that the higher occurrence of bronchiectasis in patients with IBD is not caused by genetic predisposition.

Claves:Crohn’s disease, bronchiectasis, causal relationship, inflammatory bowel disease, mendelian randomization, ulcerative colitis

Cita:Front Immunol 2024; 15 : 1365108.

Autor/es:Zeng, Qian (a)
Hu, Da (b)

institución:(a) Department of General Practice, Shenzhen Luohu Hospital Group Luohu People's Hospital, The Third Affiliated Hospital of Shenzhen University, Shenzhen, Guangdong, China.
(b) Department of General Practice, Shenzhen Luohu Hospital Group Luohu People's Hospital, The Third Affiliated Hospital of Shenzhen University, Shenzhen, Guangdong, China.

Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3389/fimmu.2024.1365108

Phenotypic immune characterization of gastric and esophageal adenocarcinomas reveals profound immune suppression in esophageal tumor locations.

Fuente:Frontiers in Immunology

Extracto: These findings provide an important rationale for stratification according to tumor location in clinical studies and the development of location-dependent immunomodulatory treatment approaches.

Claves:HER2, MSI, biomarkers, single cell flow cytometry, tumor microenvironment

Cita:Front Immunol 2024; 15 : 1372272.

Autor/es:Groen-van Schooten, Tessa S (a)
Harrasser, Micaela (b)

institución:(a) Department of Medical Oncology, Amsterdam University Medical Center (UMC) location Vrije Universiteit Amsterdam, Amsterdam, Netherlands.
(b) Cancer Biology and Immunology, Cancer Center Amsterdam, Amsterdam, Netherlands.

Conflicto:TdG has a consultant or advisory role in Mendus, GE Healthcare, and LAVA Therapeutics, is a co-founder and holds stock of LAVA Therapeutics, and received research funding from Idera Pharmaceuticals. MIH is consultant for Viatris, Johnson & Johnson, Alesi Surgical, BBraun, Stryker and Medtronic. All fees paid to institution. HL has consultant or advisory role in BMS, Lilly, MSD, Nordic... Pharma, Servier and receives research funding/medication: Bayer, BMS, Celgene, Janssen, Lilly, Merck, Nordic Pharma, Philips, Roche, Servier. RP has a consulting role for Medtronic BV and MicroTech Europe; speaker fee for Pentax. TF declares institutional research funding from Genentech, Adapt immune, Roche, Beigene, Astelas, BMS, Daichii Sanyo, Amgen and speaker fees from Astrazeneca, Amgen, Bayer, BMS, Lilly, MSD and Servier. SD reports: a consultant or advisory role for BMS (related to checkpoint inhibitors); research funding, medication supply, or both from Incyte (related to checkpoint inhibitors); and speaker roles for Servier, BMS, and Benecke. SD reports: a consultant or advisory role for BMS (related to checkpoint inhibitors); research funding, medication supply, or both from Incyte (related to checkpoint inhibitors); and speaker roles for Servier, BMS, and Benecke. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3389/fimmu.2024.1372272

Unraveling the complexities of early-onset colorectal cancer: a perspective on dietary and microbial influences.

Unraveling the complexities of early-onset colorectal cancer: a perspective on dietary and microbial influences.

Fuente:Frontiers in Public Health

Extracto: This will be crucial in developing comprehensive preventive strategies to address the increasing incidence of this malignancy in younger populations.

Claves:antibiotic use, early onset colorectal cancer, gut microbiome, microbial influence, westernized diet

Cita:Front Public Health 2024; 12 : 1370108.

Autor/es:Atchade, Axelle Mayode (a)
Williams, Jennie L (b)

institución:(a) Stony Brook Medicine, Stony Brook, NY, United States.
(b) Cancer Center, Stony Brook Medicine, Stony Brook, NY, United States.

Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. The author(s) declared that they were an editorial board member of Frontiers, at the time of submission. This had no impact on the peer review process and the final decision.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3389/fpubh.2024.1370108

Case report: Cutaneous anthrax diagnosed using mNGS of a formalin-fixed paraffin-embedded tissue sample.

Case report: Cutaneous anthrax diagnosed using mNGS of a formalin-fixed paraffin-embedded tissue sample.

Fuente:Frontiers in Cellular and Infection Microbiology

Extracto: Compared with traditional bacterial culture, which is difficult to cultivate and takes a long time, mNGS can quickly and accurately help us diagnose anthrax, so that anthrax can be controlled in a timely manner and prevent the outbreak of epidemic events.

Claves:Bacillus anthracis, FFPE, case report, cutaneous anthrax, formalin-fixed paraffin-embedded, metagenomic next-generation sequencing (mNGS)

Cita:Front Cell Infect Microbiol 2024; 14 : 1329235.

Autor/es:Zhang, Jin (a)
Hou, Xin-Yi (b)

institución:(a) Department of Clinical Medicine, Jining Medical University, Jining, Shandong, China.
(b) Department of Dermatology, Affiliated Hospital of Jining Medical University, Jining, Shandong, China.

Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3389/fcimb.2024.1329235

Targeted remodeling of the human gut microbiome using Juemingzi (Senna seed extracts).

Fuente:Frontiers in Cellular and Infection Microbiology

Extracto: Overall, the very specific effects of these extracts may offer the potential for targeted antimicrobial uses or as a tool in the targeted remodeling of the gut microbiome.

Claves:Bacteroidota, Enterobacteriaceae, SIFR®, Senna, ex vivo, gut microbiome, metagenomics, preclinical research

Cita:Front Cell Infect Microbiol 2024; 14 : 1296619.

Autor/es:Narrowe, Adrienne B (a)
Lemons, Johanna M S (b)

institución:(a) Dairy and Functional Foods Research Unit, Eastern Regional Research Center, Agricultural Research Service, United States Department of Agriculture, Wyndmoor, PA, United States.
(b) Dairy and Functional Foods Research Unit, Eastern Regional Research Center, Agricultural Research Service, United States Department of Agriculture, Wyndmoor, PA, United States.

Conflicto:Authors PV, AB, and SD were employed by the company Cryptobiotix SA. Mention of trade names or commercial products in this publication is solely for the purpose of providing specific information and does not imply recommendation or endorsement by the U.S. Department of Agriculture. USDA is an equal opportunity provider and employer. The remaining authors declare that the research was... conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3389/fcimb.2024.1296619

Gut microbiota's influence on erysipelas: evidence from a two-sample Mendelian randomization analysis.

Fuente:Frontiers in Cellular and Infection Microbiology

Extracto: Our MR analysis suggests both potentially beneficial and harmful causal relationships between various gut microbiota and the incidence of erysipelas. This study provides new theoretical and empirical insights into the pathogenesis of erysipelas and underscores the potential for innovative preventive and therapeutic approaches.

Claves:Mendelian randomization, causal inference, erysipelas, genetics, gut microbiota

Cita:Front Cell Infect Microbiol 2024; 14 : 1371591.

Autor/es:Bao, Lijie (a)
Wang, Zehui (b)

institución:(a) Department of Emergency, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi, China.
(b) Department of Emergency, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi, China.

Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3389/fcimb.2024.1371591

Proposal of model for personalized early adapted cancer screening in people living with HIV: experience of "Gaetano Martino" Hospital University of Messina.

Proposal of model for personalized early adapted cancer screening in people living with HIV: experience of "Gaetano Martino" Hospital University of Messina.

Fuente:European Review For Medical and Pharmacological Sciences

Extracto: In addition, our multidisciplinary approach has also included vaccine screening, offered by the "Gaetano Martino" hospital and useful for preventing the development of specific forms of cancer in the entire population and particularly in PLWH.

Cita:Eur Rev Med Pharmacol Sci 2024 Apr; 28 (7) : 2929-2942.

Autor/es:Pellicanò, G F (a)
Squeri, A (b)

institución:Pellicanò, G F (a)
Squeri, A (b)

Formato:Informe impreso

Idioma:Inglés

País de fuente:Italia

Sitio web:http://dx.doi.org/10.26355/eurrev_202404_35924

Nationwide Association of Surgical Performance of Minimally Invasive Esophagectomy With Patient Outcomes.

Nationwide Association of Surgical Performance of Minimally Invasive Esophagectomy With Patient Outcomes.

Fuente:Jama Network Open

Tipo de trabajo:Estudio de cohortes

Extracto: AND RELEVANCE: These findings suggest that better surgical performance is associated with fewer perioperative complications for patients with esophageal cancer on a national level. If surgical performance of MIE can be improved with MIE-CAT implementation, substantially better patient outcomes may be achievable.

Cita:JAMA Netw Open 2024 Apr 1; 7 (4) : e246556.

Autor/es:Ketel, Mirte H M (a)
Klarenbeek, Bastiaan R (b)

institución:(a) Department of Surgery, Radboud University Medical Center, Nijmegen, the Netherlands.
(b) Department of Surgery, Radboud University Medical Center, Nijmegen, the Netherlands.

Conflicto:Conflict of Interest Disclosures: Dr Klarenbeek reported receiving grants from Medtronic, Stichting Bergh in het Zadel, ZonMw, and BENEFIT outside the submitted work. Dr van Det reported receiving proctor and consulting fees from Intuitive Surgical outside the submitted work. Dr Wijnhoven reported receiving grants and speaker’s fees paid to his institution from Bristol-Myers Squibb outside the submitted work. Dr van... an Workum reported receiving grants and other support from Medtronic outside the submitted work. No other disclosures were reported.

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1001/jamanetworkopen.2024.6556

Virulence, antibiotic resistance phenotypes and molecular characterisation of Vibrio furnissii isolates from patients with diarrhoea.

Virulence, antibiotic resistance phenotypes and molecular characterisation of Vibrio furnissii isolates from patients with diarrhoea.

Fuente:Bmc Infectious Diseases

Extracto: This study showed that diarrhoea associated with V. furnissii occurred sporadically and was more common than expected in the summer in Beijing, China. The antibiotic resistance of V. furnissii has unique characteristics compared with that of V. fluvialis. Fluoroquinolones and third-generation cephalosporins, such as ceftazidime and doxycycline, were effective at treating V. furnissii infection. Continua laboratory-based surveillance is needed for the prevention and control of V. furnissii infection, especially the dissemination of the antibiotic resistance genes in this pathogen.

Claves:Vibrio furnissii, Antibiotic resistance, Genomics, Phylogeny, Virulence genes

Cita:BMC Infect Dis 2024 Apr 19; 24 (1) : 412.

Autor/es:Zhou, Yanyan (a)
Yu, Li (b)

institución:(a) Department of Clinical Laboratory Medicine, Beijing Friendship Hospital, Capital Medical University, Beijing, 100052, China.
(b) Beijing Municipal Center for Disease Prevention and Control, Beijing, 100013, China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12879-024-09273-5

C16, a PKR inhibitor, suppresses cell proliferation by regulating the cell cycle via p21 in colorectal cancer.

C16, a PKR inhibitor, suppresses cell proliferation by regulating the cell cycle via p21 in colorectal cancer.

Fuente:Scientific Reports

Extracto: Thus, PKR inhibitors may serve as a new treatment option for patients with CRC.

Claves:C16, Cell cycle, Colorectal cancer, Tumor growth

Cita:Sci Rep 2024 Apr 19; 14 (1) : 9029.

Autor/es:Hashimoto, Yu (a)
Tokumoto, Yoshio (b)

institución:(a) Department of Gastroenterology and Metabology, Ehime University Graduate School of Medicine, Shitsukawa, Toon, Ehime, 791-0295, Japan.
(b) Department of Gastroenterology and Metabology, Ehime University Graduate School of Medicine, Shitsukawa, Toon, Ehime, 791-0295, Japan. yotoku@m.ehime-u.ac.jp.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1038/s41598-024-59671-7

Interpretable machine learning-based clinical prediction model for predicting lymph node metastasis in patients with intrahepatic cholangiocarcinoma.

Interpretable machine learning-based clinical prediction model for predicting lymph node metastasis in patients with intrahepatic cholangiocarcinoma.

Fuente:Bmc Gastroenterology

Extracto: The proposed ML-based predicted models had a good performance to predict LNM of patients with ICC. XGB performed best. A web calculator based on the ML algorithm showed promise in assisting clinicians to predict LNM and developed individualized medical plans.

Claves:Intrahepatic cholangiocarcinoma, Lymph node metastasis, Machine learning algorithms, Web calculator

Cita:BMC Gastroenterol 2024 Apr 19; 24 (1) : 137.

Autor/es:Xie, Hui (a)
Hong, Tao (b)

institución:(a) Department of General Surgery, Yan 'an People's Hospital, Yan 'an, China.
(b) Department of Cardiac Surgery, Fuwai Hospital Chinese Academy of Medical Sciences, Shenzhen, China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12876-024-03223-w

Genomic characterization and detection of potential therapeutic targets for peritoneal mesothelioma in current practice.

Genomic characterization and detection of potential therapeutic targets for peritoneal mesothelioma in current practice.

Fuente:Clinical and Experimental Medicine

Extracto: Although these therapies are currently not available for patients with PeM, ongoing developments might result in new treatment options in the future.

Claves:Foundation medicine, Next generation sequencing, Peritoneal mesothelioma, Targeted therapy

Cita:Clin Exp Med 2024 Apr 20; 24 (1) : 80.

Autor/es:van Kooten, Job P (a)
Dietz, Michelle V (b)

institución:(a) Department of Surgical Oncology and Gastrointestinal Surgery, Erasmus MC Cancer Institute, P.O. Box 2040, 3000, CA, Rotterdam, the Netherlands.
(b) Department of Surgical Oncology and Gastrointestinal Surgery, Erasmus MC Cancer Institute, P.O. Box 2040, 3000, CA, Rotterdam, the Netherlands. m.dietz@erasmusmc.nl.

Conflicto:NGS by use of the Foundation Medicine (FMI) F1CDx platform was financially supported by Roche. The authors report no further competing interests.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Italia

Sitio web:http://dx.doi.org/10.1007/s10238-024-01342-y

Circ_0087851 suppresses colorectal cancer malignant progression through triggering miR-593-3p/BAP1-mediated ferroptosis.

Circ_0087851 suppresses colorectal cancer malignant progression through triggering miR-593-3p/BAP1-mediated ferroptosis.

Fuente:Journal of Cancer Research and Clinical Oncology

Extracto: Circ_0087851 performed as a tumor suppressor and ferroptosis promoter by the miR-593-3p/BAP1 axis, providing novel biomarker and therapeutic target for the clinical management of CRC.

Claves:BAP1, Circ_0087851, Colorectal cancer, Ferroptosis, MiR-593-3p

Cita:J Cancer Res Clin Oncol 2024 Apr 20; 150 (4) : 204.

Autor/es:Huang, Ming (a)
Gao, Ting (b)

institución:(a) Department of Pathology, Affiliated Hospital of Xiangnan University, Chenzhou, 423000, Hunan, China.
(b) Department of Pathology, Affiliated Hospital of Xiangnan University, Chenzhou, 423000, Hunan, China.

Conflicto:The authors declare that they have no conflict of interest regarding this study.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Alemania

Sitio web:http://dx.doi.org/10.1007/s00432-024-05643-3

(68)Ga-FAPI-04 positron emission tomography/CT and laparoscopy for the diagnosis of occult peritoneal metastasis in newly diagnosed locally advanced gastric cancer

(68)Ga-FAPI-04 positron emission tomography/CT and laparoscopy for the diagnosis of occult peritoneal metastasis in newly diagnosed locally advanced gastric cancer

Fuente:Bmj Open

Tipo de trabajo:Estudio de cohortes

Extracto: TRIAL REGISTRATION NUMBER: ChiCTR2300067591.

Claves:diagnostic imaging, gastrointestinal tumours

Cita:BMJ Open 2024 Apr 19; 14 (4) : e075680.

Autor/es:Zhang, Shunyu (a)
Hu, Qiancheng (b)

institución:(a) Department of Medical Oncology, Cancer Center, West China Hospital of Sichuan University, Chengdu, Sichuan, China.
(b) Gastric Cancer Center, Sichuan University West China Hospital, Chengdu, Sichuan, China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1136/bmjopen-2023-075680

Alterations of the duodenal mucosal microbiome in patients with metabolic dysfunction-associated steatotic liver disease.

Alterations of the duodenal mucosal microbiome in patients with metabolic dysfunction-associated steatotic liver disease.

Fuente:Scientific Reports

Extracto: Our findings reveal the duodenal mucosal microbiota in patients with MASLD, which could contribute to future studies investigating the causal relationship between duodenal microbiota and MASLD.

Claves:Gut microbiota, Metabolic dysfunction-associated steatotic liver disease, Mucosa-associated microbiota, Small intestine

Cita:Sci Rep 2024 Apr 21; 14 (1) : 9124.

Autor/es:Ren, Mengting (a)
Pan, Hanghai (b)

institución:(a) Department of Gastroenterology, The First Affiliated Hospital, Zhejiang University School of Medicine, 79 Qingchun Road, Hangzhou, 310003, Zhejiang, China.
(b) Cancer Center, Department of Gastroenterology, Zhejiang Provincial People's Hospital (Affiliated People's Hospital), Hangzhou Medical College, 158 Shangtang Road, Hangzhou, 310014, Zhejiang, China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1038/s41598-024-59605-3

Prevalence of breast cancer in rural population of Jaipur: a survey-based observational study.

Fuente:Scientific Reports

Extracto: Prioritizing rural healthcare and evidence-based strategies can reduce the burden of breast cancer and improve health outcomes.

Claves:Breast cancer, Physical screening, Prevalence, Rural

Cita:Sci Rep 2024 Apr 17; 14 (1) : 8865.

Autor/es:Singh, Roshni (a)
Kumar, Sachin (b)

institución:(a) Department of Pharmacy Practice, Institute of Pharmacy, Nims University Rajasthan, Jaipur, India.
(b) Department of Pharmacy Practice, Institute of Pharmacy, Nims University Rajasthan, Jaipur, India.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1038/s41598-024-58717-0