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La creciente cantidad de artículos con Acceso Abierto (Open
Access) amplía la oferta de lectura pero a su vez también, entre
tanta abundancia, complica al lector en su encuentro con los estudios
fundamentales. Para facilitarlo, profesionales biomédicos de SIIC
consultan diariamente una profusa cantidad de documentos que nutrirán
Textos completos autorizados (TCA).
Las citas de la sección TCA enlazan de manera legal, autorizada y
gratuita con los textos completos (full text) publicados en
los sitios oficiales de sus respectivas fuentes.
SIIC creó, produjo y opera con exclusividad el software TCA para la
interpretación de los diversos campos documentales que integran la
estructura de un estudio: especialidad, modalidad del estudio,
fuente, fechas de publicación y selección, definición de la fuente,
limitaciones de consulta, resumen en castellano, etc.
Si bien la mayoría de los textos seleccionados corresponden a
artículos originales, revisiones y guías, los lectores también
encontrarán comentarios, entrevistas, notas periodísticas, cartas a
autores u otros textos precursores de debates o aclaratorios.
Sociedad Iberoamericana de Información Científica (SIIC) selects
complete quality-full texts which have been recently published in
renowned sources worldwide and are indexed by SIIC Data
Bases.
The increasing number of Open Access articles widens the reading offer
but, also, such myriad complicates the readers search of fundamental
articles. To facilitate this, SIIC biomedical professionals daily
consult a profuse amount of documents that will feed
Authorized Full Texts (TCA, Spanish acronym).
The citations of the AFT section link legally, authorized and free of
charge with the full texts published in the official web sites of
their corresponding sources.
SIIC created, produced and handles the AFT software that deciphers
the various documentary fields that form part of the structure of a
study: specialty, study style, source, publication and selection
dates, source definition, query limitations, summary in Spanish,
etc.
While most of the selected texts belong to original articles,
reviews, and guidelines, readers will also find commentaries,
interviews, journalistic reports, letters to authors or other texts
that may lead to discussions or clarifications.
Gut microbiota plays a key role in the development of colorectal cancer.
Gut microbiota plays a key role in the development of colorectal cancer.
Fuente:World Journal of Gastroenterology
Extracto:
Specifically, the genera Bacteroides, Campylobacter, Peptostreptococcus,
and Parvimonas were found to be elevated in individuals with CRC, while
Faecalibacterium, Haemophilus, and Phocaeicola were more prevalent in the non-
CRC group.
Claves:Colorectal cancer, Gut metabolites, Gut microbiota, Intratumoral microbiota, Microbial dysbiosis
institución:(a) Department of Gastroenterology, The First Affiliated Hospital of University of Science and Technology of China (USTC), Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei 230001, Anhui Province, China. (b) Department of Gastroenterology, The First Affiliated Hospital of University of Science and Technology of China (USTC), Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei 230001, Anhui Province, China. feixilj@163.com.
Conflicto:Conflict-of-interest statement: All authors declare no conflict of interest in publishing the manuscript.
Clinical, genetic and functional perspectives on ATP-binding cassette subfamily B member 4 variants in five cholestasis adults.
Clinical, genetic and functional perspectives on ATP-binding cassette subfamily B member 4 variants in five cholestasis adults.
Fuente:World Journal of Gastroenterology
Extracto:
This
study uncovered new ABCB4 variants and emphasized the pathogenic potential of
specific variants. The findings from five patients provided insight into the
pathogenic mechanisms underlying ABCB4-related diseases.
Claves:ATP-binding cassette subfamily B member 4, Cholestasis, Clinical, Functional analysis, Gene mutation, Multidrug resistance protein 3, Whole-exome sequencing
institución:(a) Department of Hepatology, The Second Hospital of Nanjing, The Affiliated to Nanjing University of Chinese Medicine, The Affiliated to Southeast University Medical School, Nanjing 210003, Jiangsu Province, China. (b) Department of Hepatology, The Second Hospital of Nanjing, The Affiliated to Nanjing University of Chinese Medicine, The Affiliated to Southeast University Medical School, Nanjing 210003, Jiangsu Province, China.
Conflicto:Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Study of the relationship between iron metabolism disorders and sepsis-associated liver injury: A prospective observational study.
Study of the relationship between iron metabolism disorders and sepsis-associated liver injury: A prospective observational study.
Fuente:World Journal of Gastroenterology
Extracto:
Iron
metabolism disorders are closely associated with the development of SALI, and SI
and TIBC may serve as potential predictive biomarkers. The combined use of SI and
TIBC has superior diagnostic efficacy for SALI. These findings provide valuable
insights for the early identification and management of SALI among patients with
sepsis.
Claves:Biomarkers, Iron metabolism, Liver injury, Sepsis, Serum iron, Total iron-binding capacity
institución:(a) Department of Intensive Care Unit, Northern Jiangsu People's Hospital Affiliated to Yangzhou University, Yangzhou 225001, Jiangsu Province, China. (b) Department of Intensive Care Unit, Northern Jiangsu People's Hospital Affiliated to Yangzhou University, Yangzhou 225001, Jiangsu Province, China.
Conflicto:Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Rapid pathologic grading-based diagnosis of esophageal squamous cell carcinoma via Raman spectroscopy and a deep learning algorithm.
Rapid pathologic grading-based diagnosis of esophageal squamous cell carcinoma via Raman spectroscopy and a deep learning algorithm.
Fuente:World Journal of Gastroenterology
Extracto:
Raman spectroscopy revealed significantly different
waveforms for the different stages of esophageal neoplasia. The combination of
Raman spectroscopy and deep learning methods could significantly improve the
accuracy of classification.
institución:(a) Department of Gastroenterology, Beijing Tiantan Hospital, Capital Medical University, Beijing 100071, China. (b) Department of Cancer Prevention Center, Feicheng People's Hospital, Feicheng 271000, Shandong Province, China.
Conflicto:Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Cuproptosis-related gene ACAD8 inhibits the metastatic ability of colorectal cancer by inducing cuproptosis.
Cuproptosis-related gene ACAD8 inhibits the metastatic ability of colorectal cancer by inducing cuproptosis.
Fuente:Frontiers in Immunology
Extracto:
As a novel tumor suppressor,
low expression of CRGs-ACAD8 is associated with the metastasis of CRC. ACAD8
holds potential diagnostic and prognostic value and may contribute to the precise
treatment of CRC by regulating immune infiltration and chemotherapy sensitivity.
institución:(a) Department of Gastroenterology, The Second Affiliated Hospital of Fujian Medical University, Quanzhou, Fujian, China. (b) Fujian Medical University, Fuzhou, Fujian, China.
Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Novel and Effective Blood-Based miRNA Diagnostic Panel for Gastric Cancer: A Pilot Study in a Japanese Population.
Novel and Effective Blood-Based miRNA Diagnostic Panel for Gastric Cancer: A Pilot Study in a Japanese Population.
Fuente:Cancer Medicine
Tipo de trabajo:Estudio de cohortes
Extracto:
GASTROClear demonstrated
competent diagnostic efficacy for GC in the detection of GC in our Japanese
cohort, even in the early stages of cancer and asymptomatic cases. Its
combination with existing serum markers may contribute to efficient risk
stratification to detect GC.
Claves:blood, early detection of cancer, gastric cancer, liquid biopsy, miRNA
Cita:Cancer Med 2025 Apr; 14 (8) : e70790.
Autor/es:Murano, Tatsuro (a) Chung, Ka Yan (b)
institución:(a) Department of Gastroenterology and Endoscopy, National Cancer Center Hospital East, Chiba, Japan. (b) MiRXES Lab Pte Ltd., Singapore.
Conflicto:L.Z. is the co‐founder and shareholder of MiRXES. K.Y.C., Y.G., Y.C.T., H.C., and L.Z. are employees of MiRXES. J.K.C. is partially supported by MiRXES through a manpower secondment scheme from the National University of Singapore. Other authors have no competing interests to declare that are relevant to the content of this article.
Regional Differences in the Frequency of BRCA1 and BRCA2 Variants in Northeastern Japan
Regional Differences in the Frequency of BRCA1 and BRCA2 Variants in Northeastern Japan
Fuente:Cancer Medicine
Tipo de trabajo:Estudio de cohortes
Extracto:
These results highlight the importance of considering regional
differences in comparative cohort studies, particularly in assessing the
differential extension of mutations in pathogenic changes and VUS. Moreover, a
presumption of pathogenicity variants would need to be discussed at the regional
level.
institución:(a) Department of Medical Oncology, Tohoku University Hospital, Sendai, Japan. (b) Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Air Temperature and Gastroenteritis Among Rohingya Populations in Bangladesh Refugee Camps.
Air Temperature and Gastroenteritis Among Rohingya Populations in Bangladesh Refugee Camps.
Fuente:Jama Network Open
Tipo de trabajo:Caso clínico
Extracto:
AND RELEVANCE: In this cross-sectional study of the
Rohingya displaced population in Bangladesh, cold temperatures were associated
with an increase in the risk of gastroenteritis. It is important to understand
the association of climatic factors with the health of displaced communities,
whose population is expected to grow in the future.
Cita:JAMA Netw Open 2025 Apr 1; 8 (4) : e255768.
Autor/es:Takata, Takuya (a) Seposo, Xerxes (b)
institución:(a) Department of Hygiene, Faculty of Medicine, Graduate School of Medicine, Hokkaido University, Sapporo, Japan. (b) Department of Hygiene, Faculty of Medicine, Graduate School of Medicine, Hokkaido University, Sapporo, Japan.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
HIV and Non-HIV Patients Have Similar Rates of Neoplastic Findings on Screening Colonoscopy Within a Predominantly African American Cohort.
HIV and Non-HIV Patients Have Similar Rates of Neoplastic Findings on Screening Colonoscopy Within a Predominantly African American Cohort.
Fuente:Cancer Medicine
Tipo de trabajo:Revisión
Extracto:
CRC screening
recommendations are appropriate for the HIV patient population without
limitation.
Claves:antiretroviral therapy, colorectal cancer, human immunodeficiency virus, screening colonoscopy
Cita:Cancer Med 2025 Apr; 14 (8) : e70811.
Autor/es:Mude, Pooja (a) Thomson, Alexandra E (b)
institución:(a) Department of Medicine, Medical College of Georgia at Augusta University, Augusta, Georgia, USA. (b) Department of Medicine, Memorial Health University Medical Center-HCA, Savannah, Georgia, USA.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Cancer Incidence in Kabul, Afghanistan: The First Report From the Population-Based Cancer Registry.
Cancer Incidence in Kabul, Afghanistan: The First Report From the Population-Based Cancer Registry.
Fuente:Cancer Medicine
Extracto:
The high incidence of breast, stomach, and esophagus cancers
highlights the need for policymakers and healthcare providers to develop cancer
control programs focused on primary prevention, early detection, and quality
diagnosis and treatment. Additionally, this study underscores the importance of
cancer registries and emphasizes the need to strengthen the KCR to improve data
quality.
Claves:cancer in Afghanistan, cancer in Kabul, cancer incidence, cancer registry, common cancers in Kabul, population‐based
Cita:Cancer Med 2025 Apr; 14 (8) : e70844.
Autor/es:Abdullah, Maihan (a) Niazi, Nisar (b)
institución:(a) Ministry of Public Health, Kabul, Afghanistan. (b) Takemi Program in International Health, Harvard T.H. Chan School of Public Health, Harvard University, Boston, Massachusetts, USA.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Do Nutritional and Inflammatory Indices Predict Response in Geriatric Gastric Cancer Patients Treated with Neoadjuvant FLOT Regimen?
Do Nutritional and Inflammatory Indices Predict Response in Geriatric Gastric Cancer Patients Treated with Neoadjuvant FLOT Regimen?
Fuente:Cancer Control Journal of The Moffitt Cancer Center
Extracto:
However, larger prospective, multicenter
studies are required to confirm this relationship.
Claves:chemotherapy, gastric cancer, geriatric oncology, neoadjuvant treatment, nutritional indices
Cita:Cancer Control 2025 Jan-Dec; 32 : 10732748251335367.
Autor/es:Ürün, Yonca Yılmaz (a) Ürün, Muslih (b)
institución:(a) Department of Gastroenterology and Hepatology, Van Yüzüncü Yıl University Medical Faculty, Van, Turkey. (b) Department of Medical Oncology, Van Yüzüncü Yıl University Medical Faculty, Van, Turkey.
Conflicto:Conflicting InterestsThe authors declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
Mendelian randomization study of sleep traits and risk of colorectal cancer.
Mendelian randomization study of sleep traits and risk of colorectal cancer.
Fuente:Scientific Reports
Extracto:
Overall, this study
provides little to no evidence of an association between genetically predicted
sleep traits and CRC risk.
Cita:Sci Rep 2025 Apr 18; 15 (1) : 13478.
Autor/es:Dimopoulou, Olympia (a) Fuller, Harriett (b)
institución:(a) Department of Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK. olympia.dimopoulou@bristol.ac.uk. (b) MRC Integrative Epidemiology Unit, Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK. olympia.dimopoulou@bristol.ac.uk.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
institución:(a) Department of Gastroenterology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, 310016, China. (b) Department of General Surgery, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, 310016, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Silencing PPP2R1A inhibits the progression of gastric cancer cells.
Silencing PPP2R1A inhibits the progression of gastric cancer cells.
Fuente:Journal of Cancer Research and Clinical Oncology
Extracto:
PPP2R1A has potential
oncogenic properties in the progression of GC, and knocking down the expression
of PPP2R1A can inhibit the tumor progression of GC cells. This suggests that
PPP2R1A may serve as a potential prognostic marker and therapeutic target for GC.
Claves:PPP2R1A, Cell apoptosis, Cell migration and invasion, Cell proliferation, Gastric cancer
Cita:J Cancer Res Clin Oncol 2025 Apr 18; 151 (4) : 142.
institución:(a) Gastrointestinal Surgery Department, Xinjiang Medical University Affiliated Cancer Hospital, Xinjiang Uygur Autonomous Region, Urumqi, 830011, People's Republic of China. (b) Gastrointestinal Surgery Department, Xinjiang Medical University Affiliated Cancer Hospital, Xinjiang Uygur Autonomous Region, Urumqi, 830011, People's Republic of China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Effect of biliopancreatic tree anatomy on development of acute gallstone pancreatitis.
Effect of biliopancreatic tree anatomy on development of acute gallstone pancreatitis.
Fuente:Bmc Gastroenterology
Extracto:
Anatomy of the biliopancreatic tree
and its variations are related to acute gallstone pancreatitis. Several proposed
mechanism are thought to play role in this phenomenon but future prospective
studies are required to reveal more on the topic.
Autor/es:Alparslan, Ahmet Sukru (a) Ocal, Serkan (b)
institución:(a) Department of Radiology, Antalya Training and Research Hospital, University of Health Sciences, Antalya, Turkey. (b) Department of Gastroenterology, Antalya Training and Research Hospital, University of Health Sciences, Antalya, Turkey.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Effect of Saccharomyces boulardii supplementation to bismuth quadruple therapy on Helicobacter pylori eradication.
Effect of Saccharomyces boulardii supplementation to bismuth quadruple therapy on Helicobacter pylori eradication.
Fuente:Bmc Gastroenterology
Tipo de trabajo:Estudio aleatorizado y controlado
Extracto:
The addition of S. boulardii to bismuth quadruple
therapy significantly increased H. pylori eradication rates and decreased the
adverse effects. We recommend adding 500 mg/day S. boulardii concurrently with
bismuth quadruple therapy and continuing this therapy for > 10 days for optimal
H. pylori eradication efficacy.
institución:(a) Department of Gastroenterology, Changzhou Medical Center, The Third Affiliated Hospital of Nanjing Medical University, Nanjing Medical University, 68 Gehu middle road, Wujing District, Changzhou, Jiangsu Province, 213000, China. (b) Department of Gastroenterology, Changzhou Medical Center, The Third Affiliated Hospital of Nanjing Medical University, Nanjing Medical University, 68 Gehu middle road, Wujing District, Changzhou, Jiangsu Province, 213000, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Meta-analysis of the efficacy of applying reduced surgery for the treatment of asymptomatic unresectable advanced gastric cancer.
Meta-analysis of the efficacy of applying reduced surgery for the treatment of asymptomatic unresectable advanced gastric cancer.
Fuente:Bmc Gastroenterology
Tipo de trabajo:Metanálisis
Extracto:
Current evidence suggests that in
asymptomatic patients with unresectable advanced gastric cancer, reduced surgery
with resection of the primary site does not result in a long-term survival
benefit. We look forward to more high-quality randomized controlled trials to
provide more substantial evidence to support clinical practice.
Optimizing prediction of metastasis among colorectal cancer patients using machine learning technology.
Optimizing prediction of metastasis among colorectal cancer patients using machine learning technology.
Fuente:Bmc Gastroenterology
Tipo de trabajo:Estudio clínico
Extracto:
The current empirical results indicated that LighGBM has predictive
competency that can be leveraged by physicians in clinical environments for early
prediction of metastasis and enhanced prognosis in patients with colorectal
cancer. CLINICAL TRIAL NUMBER: Not applicable.
Associations between non-insulin-based insulin resistance surrogate markers and liver-related outcomes in metabolic dysfunction-associated steatotic liver disease
Associations between non-insulin-based insulin resistance surrogate markers and liver-related outcomes in metabolic dysfunction-associated steatotic liver disease
Fuente:Bmc Gastroenterology
Tipo de trabajo:Estudio de cohortes
Extracto:
A lower non-insulin-based
IR surrogate marker in the MASLD group may be associated with an increased risk
of liver-related outcomes. In the course of monitoring MASLD, metabolic
alterations must be meticulously observed.
institución:(a) Department of Internal Medicine, Dong-A University College of Medicine, 32 Daesingongwon-ro, Seo-gu, Busan, 49201, South Korea. sang4401@dau.ac.kr. (b) Department of Data Sciences Convergence, Dong-A University Interdisciplinary Program, Busan, South Korea. sang4401@dau.ac.kr.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
