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Computed tomography-based radiomic features combined with clinical parameters for predicting post-infectious bronchiolitis obliterans in children with adenovirus pneumonia: a retrospective study.
Computed tomography-based radiomic features combined with clinical parameters for predicting post-infectious bronchiolitis obliterans in children with adenovirus pneumonia: a retrospective study.
Fuente:Peerj
Extracto:
Combining
CT-based radiomic features with clinical parameters can offer an effective
noninvasive model to predict BO in children with adenovirus pneumonia.
institución:(a) Department of Radiology Children's Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Key Laboratory of Pediatric Metabolism and Inflammatory Diseases, Chongqing, China. (b) Department of Radiology Children's Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Key Laboratory of Pediatric Metabolism and Inflammatory Diseases, Chongqing, China.
Conflicto:Fang Wang, Man Li and Yang Li are employed by Shanghai United lmaging Intelligence Co., Ltd.
Using a Hybrid of AI and Template-Based Method in Automatic Item Generation to Create Multiple-Choice Questions in Medical Education: Hybrid AIG.
Using a Hybrid of AI and Template-Based Method in Automatic Item Generation to Create Multiple-Choice Questions in Medical Education: Hybrid AIG.
Fuente:Jmir Formative Research
Tipo de trabajo:Revisión
Extracto:
The hybrid AIG method transcends the traditional template-based
approach by marrying the "art" that comes from AI as a "black box" with the
"science" of algorithmic generation under the oversight of expert as a "marriage
registrar". It does not only capitalize on the strengths of both approaches but
also mitigates their weaknesses, offering a human-AI collaboration to increase
efficiency in medical education.
Claves:AI, ChatGPT, algorithm, artificial intelligence, automatic item generation, expert, human-AI, human-AI collaboration, hybrid, hybrid AIG, large language models, medical education, mixed-method, multiple-choice, multiple-choice question, template-based method
Cita:JMIR Form Res 2025 Apr 4; 9 : e65726.
Autor/es:Kıyak, Yavuz Selim (a) Kononowicz, Andrzej A (b)
institución:(a) Department of Medical Education and Informatics, Faculty of Medicine, Gazi University, Ankara, Turkey. (b) Department of Bioinformatics and Telemedicine, Jagiellonian University Medical College, Medyczna Str 7, Kraków, 30-688, Poland, 48 12 3476908.
Traditional Chinese medicine-based therapeutics for Pediatric pneumonia-related acute lung injury and acute respiratory distress syndrome.
Traditional Chinese medicine-based therapeutics for Pediatric pneumonia-related acute lung injury and acute respiratory distress syndrome.
Fuente:Scientific Reports
Extracto:
The findings from this
study may pave the way for the development of effective TCM-based therapies for
pediatric pneumonia, offering a promising alternative to current treatment
modalities.
Claves:Molecular dynamic simulation, Pediatric Pneumonia, Pharmacokinetics, Traditional Chinese medicine
Cita:Sci Rep 2025 Apr 5; 15 (1) : 11708.
Autor/es:Pan, Yuexin (a) Gangwar, Shalesh (b)
institución:(a) Shandong University of Traditional Chinese Medicine, Jinan, 250335, China. (b) Computational Intelligence and Bioinformatics Lab, Department of Computer Science, Jamia Millia Islamia, New Delhi, India.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Separation of thoracic and abdominal measurements in neonatal vital sign monitoring using radar vision fusion system.
Separation of thoracic and abdominal measurements in neonatal vital sign monitoring using radar vision fusion system.
Fuente:Scientific Reports
Extracto:
We report maximum root mean square
errors of 2.16 Beats Per Minute(BPM) for RR measurements and 3.54 BPM for HR
measurements.
Cita:Sci Rep 2025 Apr 6; 15 (1) : 11800.
Autor/es:Jiang, Nanyi (a) Liang, Xuerui (b)
institución:(a) National Key Laboratory of Microwave Imaging Technology, Aerospace Information Research Institute, Chinese Academy of Sciences, Beijing, 100190, China. jiangnanyi18@mails.ucas.ac.cn. (b) School of Electronic, Electrical and Communication Engineering, University of Chinese Academy of Sciences, Beijing, 100049, China. jiangnanyi18@mails.ucas.ac.cn.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
institución:(a) Department of Laboratory Medicine, Fujian Key Clinical Specialty of Laboratory Medicine, Women and Children's Hospital, School of Medicine, Xiamen University, Xiamen, 361003, China. (b) Department of Pediatrics, Women and Children's Hospital, School of Medicine, Xiamen University, No. 10, Zhenhai Road, Siming District, Xiamen, 361003, China. 1010030793@qq.com.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Lower respiratory rate during sleep in children with angelman syndrome compared to age-matched controls.
Lower respiratory rate during sleep in children with angelman syndrome compared to age-matched controls.
Fuente:Orphanet Journal of Rare Diseases
Extracto:
Our study provides the first long-term observational
evidence of a persistent bradypnea-like phenotype in individuals with AS, which
may have significant implications for their clinical management. The successful
use of the sleep mat device as a non-invasive physiological ambulatory monitoring
tool demonstrates its potential as a digital health technology for detecting
respiratory abnormalities in pediatric neurodevelopmental disorders. These
findings should be further assessed and may have biomarker and clinical utility
in AS, particularly in relation to seizure management and cognitive development.
Claves:Angelman syndrome, Digital biomarkers, Respiration, Respiratory rate, Sleep disorders, Sleep mat
Autor/es:Gschwind, Leo (a) Holst, Sebastian Camillo (b)
institución:(a) Roche Pharma Research and Early Development, Data and Analytics, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd., Basel, Switzerland. (b) Roche Pharma Research and Early Development, Neuroscience and Rare Diseases, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd., Basel, Switzerland. sebastian.holst@roche.com.
Conflicto:Declarations. Ethics approval and consent to participate: All participants provided informed consent before being enrolled in the study. This study was conducted in compliance with Good Clinical Practice, including International Conference on Harmonization Guidelines and was consistent with the most recent version of the Declaration of Helsinki. Additionally, all applicable local laws and regulatory requirements were adhered to. Before recruiting...
participants, all study documents were submitted to and approved by an independent institutional review board at each site. All personal data were managed to ensure compliance with applicable national and/or local laws, and regulations on personal data protection. Consent for publication: Not applicable. Competing interests: LG, SCH, DN, FL, PB, VK and JFH are employees of F. Hoffmann-La Roche Ltd. KB was an employee of Fortrea Development Limited, Budapest, Hungary, providing services to F. Hoffmann-La Roche Ltd., when this study was conducted. AR has been a paid consultant and has received research support from F. Hoffmann-La Roche Ltd. He has also consulted, participated on advisory boards or received recent research support from Autifony, BioMarin, Brainsway, CRE Medical, CURE, Encoded, LouLou Foundation, Marino’s, Neurocrine, Neuroelectrics, Ovid, SSADH Foundation, and Takeda. He is co-founder and has equity in Neuromotion, PrevEp, and Galibra.
The RaDiCo information system for rare disease cohorts.
The RaDiCo information system for rare disease cohorts.
Fuente:Orphanet Journal of Rare Diseases
Extracto:
RaDiCo provides a robust IS,
compatible with the French Data Hub and RDs ERNs, integrated on a RD platform
that enables e-cohorts creation, monitoring and analysis.
Claves:Cloud computing, E-cohorts, European Research Network, French Data Hub, GDPR, Information system, Infrastructure as a Service, Interoperability, Rare diseases
institución:(a) Childhood Genetic Diseases Laboratory, Université de Montpellier, Inserm U933, 26 rue Arnold Netter, 75012, Montpellier, France. paul.landais@umontpellier.fr. (b) Chilhood Genetic Diseases Laboratory, Hôpital A. Trousseau, Inserm, Paris, France.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Long-term effects of a primary school-based overweight preventive intervention on physical fitness and physical activity
Long-term effects of a primary school-based overweight preventive intervention on physical fitness and physical activity
Fuente:Bmj Open
Tipo de trabajo:Estudio de cohortes
Extracto:
No evidence was found for long-term
favourable effects of a school-based multicomponent intervention on physical
fitness and PA. Recommendations for policy and future research are discussed.
Claves:Adolescent, Overweight, PUBLIC HEALTH
Cita:BMJ Open 2025 Apr 8; 15 (4) : e088272.
Autor/es:Smit, Michel Sebastiaan (a) Mölenberg, Famke (b)
institución:(a) Public Health, Erasmus MC, Rotterdam, The Netherlands. (b) Public Health, Erasmus MC, Rotterdam, The Netherlands.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Extracorporeal membrane oxygenation in the treatment of critical Pneumocystis jirovecii pneumonia in a child with Langerhans cell histiocytosis
Extracorporeal membrane oxygenation in the treatment of critical Pneumocystis jirovecii pneumonia in a child with Langerhans cell histiocytosis
Fuente:Bmc Infectious Diseases
Tipo de trabajo:Revisión
Extracto:
While PJP is a rare and
extremely serious opportunistic infection, the VA ECMO support in this pediatric
case effectively managed severe PJP without ECMO-related complications. This
highlights ECMO as a potentially viable, relatively effective, and safe
adjunctive therapy in the management of severe PJP infections in children.
Claves:Pneumocystis jirovecii pneumonia, Case report, ECMO, Langerhans cell histiocytosis
Cita:BMC Infect Dis 2025 Apr 9; 25 (1) : 492.
Autor/es:Zou, Zhuan (a) Zhao, Wanlin (b)
institución:(a) Department of Emergency, West China Second University Hospital, Sichuan University, Chengdu, China. (b) Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education, Chengdu, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Consumption of folic acid fortified foods among Hispanic women of reproductive age in the US
Consumption of folic acid fortified foods among Hispanic women of reproductive age in the US
Fuente:Bmc Public Health
Tipo de trabajo:Revisión sistemática
Extracto:
There is a paucity of
literature to describe the rate, influencing factors, and prevalence disparities
in NTD among Hispanic women living in the US despite its public health
importance. This review provides a current summary on the disparities in folic
acid intake and NTD rates between Hispanic and NHW women, and the effectiveness
of voluntary fortification targeting populations at higher risk. Research
initiatives investigating the factors influencing these disparities and future
targeted interventions are necessary.
Claves:Congenital defects, Folic acid, Hispanic women, Mexican American women, Myelomeningocele, Neural tube defects, Prenatal care
Cita:BMC Public Health 2025 Apr 9; 25 (1) : 1334.
Autor/es:Villalba, Nicole (a) Byrne, Kayla (b)
institución:(a) Division of Pediatric Neurosurgery, Ann and Robert H. Lurie Children's Hospital, Chicago, IL, USA. (b) Department of Neurosurgery, Northwestern University Feinberg School of Medicine, Northwestern Memorial Hospital, 676 N St. Clair St, Ste 2210, Chicago, IL, 60611, USA.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Cord blood IgG for respiratory syncytial virus and subsequent infection during the COVID-19 pandemic.
Cord blood IgG for respiratory syncytial virus and subsequent infection during the COVID-19 pandemic.
Fuente:Medicine
Extracto:
This
study revealed an association between lower cord blood anti-RSV IgG positivity
during the coronavirus disease 2019 pandemic compared to before the pandemic, and
an increased risk of subsequent infant/severe RSV infections.
Cita:Medicine (Baltimore) 2025 Jan 3; 104 (1) : e41110.
institución:(a) Division of Molecular Epidemiology, The Jikei University School of Medicine, Tokyo, Japan. (b) Department of Obstetrics and Gynecology, The Jikei University School of Medicine, Tokyo, Japan.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Automated Adjustment of the Fraction of Inspired Oxygen (FiO2) and the Time Spent in Normoxemia in Preterm Infants.
Automated Adjustment of the Fraction of Inspired Oxygen (FiO2) and the Time Spent in Normoxemia in Preterm Infants.
Fuente:Acta Medica Portuguesa
Extracto:
The use of closed-loop automatic control of FiO2 seems feasible and was
associated with fewer episodes of hypoxia and hyperoxia, thereby maintaining SpO2
within normal limits for longer periods. Additionally, it has been shown to be
associated with a reduction in manual interventions.
institución:(a) Department of Neonatology. Centro Hospitalar e Universitário de São João. Porto. Portugal. (b) Department of Neonatology. Centro Hospitalar e Universitário de São João. Porto. Portugal.
Construction and evaluation of machine learning-based prediction model for live birth following fresh embryo transfer in IVF/ICSI patients with polycystic ovary syndrome.
Construction and evaluation of machine learning-based prediction model for live birth following fresh embryo transfer in IVF/ICSI patients with polycystic ovary syndrome.
Fuente:Journal of Ovarian Research
Tipo de trabajo:Estudio clínico
Extracto:
This study developed a live birth prediction model tailored for PCOS fresh embryo
transfer cycles, leveraging ML algorithms to compare the efficacy of multiple
models. The XGBoost model demonstrated superior predictive capacity, enabling
prompt and precise identification of critical risk factors influencing live birth
outcomes in PCOS patients. These findings offer actionable insights for clinical
intervention, guiding strategies to improve pregnancy outcomes in this
population. CLINICAL TRIAL NUMBER: Not applicable.
Claves:Fresh embryo transfer, Live birth, Machine learning, Polycystic ovary syndrome
Cita:J Ovarian Res 2025 Apr 4; 18 (1) : 70.
Autor/es:Zhu, Suqin (a) Huang, Zhiqing (b)
institución:(a) Center of Reproductive Medicine, College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Maternity and Child Health Hospital, Fujian Medical University, No. 18 Daoshan Road, Fuzhou City, 350001, Fujian Province, China. (b) Fujian Maternal-Fetal Clinical Medicine Research Center, Fuzhou, 350001, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Clinical evaluation of Ayush-SS granules in exclusively breastfeeding mothers with insufficient lactation: A randomized, double-blind, placebo-controlled trial.
Clinical evaluation of Ayush-SS granules in exclusively breastfeeding mothers with insufficient lactation: A randomized, double-blind, placebo-controlled trial.
Fuente:International Breastfeeding Journal
Tipo de trabajo:Estudio clínico
Extracto:
Ayush-SS
granules significantly improved EBF rates at six months, maternal perceptions of
lactation sufficiency, and infant weight gain. These findings suggest their
potential as a galactagogue for mothers with insufficient milk production.
Further research is needed to explore long-term effects and maternal dietary
influences. CLINICAL TRIAL REGISTRATION: CTRI/2019/08/020579 [Registered on:
06/08/2019].
institución:(a) Department of Obstetrics & Gynecology, VMMC and Safdarjung Hospital, New Delhi, India. drupmasaxena@gmail.com. (b) Central Ayurveda Research Institute, Bhubaneswar, India.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Prognostic factors in pediatrics TAPVC: a 10-year retrospective study.
Prognostic factors in pediatrics TAPVC: a 10-year retrospective study.
Fuente:Scientific Reports
Extracto:
By
identifying the impact of these variables on survival rates and hospital
recovery, the study aims to improve risk stratification and management strategies
for better outcomes in children with TAPVC.
Claves:Echocardiography, Prognosis, Pulmonary venous obstruction, Total anomalous pulmonary venous connection
Cita:Sci Rep 2025 Apr 5; 15 (1) : 11734.
Autor/es:Xue, Xiaoying (a) Ling, Wen (b)
institución:(a) Department of Medical Ultrasonics, Fujian Maternity and Child Health Hospital, College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fuzhou, China. (b) Department of Medical Ultrasonics, Fujian Maternity and Child Health Hospital, College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fuzhou, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Avoidable visits to the paediatric emergency department: associated factors and lessons learned from the pandemic.
Avoidable visits to the paediatric emergency department: associated factors and lessons learned from the pandemic.
Fuente:Bmc Pediatrics
Extracto:
The relatively low decrease in avoidable
visits' ratios between pre-COVID and COVID periods, associated with the similar
distribution of attendance during the day and lower odds ratio of avoidable
visits during periods when primary care is available, suggests that avoidable
visits are a chronical problem of the National Health system's structure and its
usage, not having a single factor nor a combination of factors as a driving
force. Nevertheless, this study identified several factors associated with
avoidable visits to the emergency department. Therefore, it can aid policy makers
to create targeted interventions to mitigate this problem.
institución:(a) MEDCIDS - Department of Community Medicine, Information and Health Decision Sciences, Faculty of Medicine, University of Porto, Porto, Portugal. joaoviana@med.up.pt. (b) CINTESIS, R&D Unit, Faculty of Medicine, University of Porto, Porto, Portugal. joaoviana@med.up.pt.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Management and outcomes of women with placenta accreta spectrum grade 3: an INOSS multicountry multiperiod population-based study.
Management and outcomes of women with placenta accreta spectrum grade 3: an INOSS multicountry multiperiod population-based study.
Fuente:Bmc Pregnancy and Childbirth
Extracto:
Maternal
outcomes in women with grade 3 PAS varied between the three periods and
countries, alongside the evolution in prenatal screening and peri-operative
management. TRIAL REGISTRATION: For the UK: reference number: RP-PG-0608-10038.
For France: reference number: AOR12156. For Italy: reference number: Port.
PRE-839/13.
institución:(a) Université Paris Cité, INSERM, INRAE, Centre for Research in Epidemiology and StatisticS (CRESS) U 1153, Obstetrical Perinatal and Pediatric Epidemiology Research Team, EPOPé, 53 avenue de l'observatoire, Paris, 75014, France. anne.pinton@aphp.fr. (b) Department of Obstetrics and Gynecology, FHU PREMA, Trousseau Hospital, AP-HP, Sorbonne University, Paris, France. anne.pinton@aphp.fr.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Identification of N6-methyladenosine-associated ferroptosis biomarkers in cervical cancer.
Identification of N6-methyladenosine-associated ferroptosis biomarkers in cervical cancer.
Fuente:Hereditas
Extracto:
Six genes, namely ALOX12, EZH2, CA9, CDCA3, CDC25A, and
HSPB1, were identified as m6A-regulated ferroptosis biomarkers in CC. These
findings offer valuable insights into disease pathogenesis and hold promise for
advancing CC treatment and prognosis.
institución:(a) Department of Chinese Pharmacy, School of Pharmacy, Guizhou University of Traditional Chinese Medicine, Guiyang, Guizhou, China. (b) Department of Chinese Pharmacy, School of Pharmacy, Harbin University of Commerce, Harbin, Heilongjiang, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Respiratory Related Hospitalization in Children With Exposure to Meconium Aspiration or Staining.
Respiratory Related Hospitalization in Children With Exposure to Meconium Aspiration or Staining.
Fuente:Pediatric Pulmonology
Extracto:
Meconium
aspiration is associated with a higher risk of hospitalization for respiratory or
atopic complications, but meconium exposure without aspiration is not associated
with these outcomes.
Claves:allergy and immunology, asthma, bronchiolitis, meconium, meconium aspiration syndrome
Cita:Pediatr Pulmonol 2025 Apr; 60 (4) : e71085.
Autor/es:Côté-Corriveau, Gabriel (a) Lasry, Ariane (b)
institución:(a) Department of Pediatrics, Sainte-Justine Hospital Research Centre, Montreal, Quebec, Canada. (b) Department of Pediatrics, University of Montreal, Montreal, Quebec, Canada.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
