Evaluation of radiological capacity and usage in paediatric TB diagnosis: A mixed-method protocol of a comparative study in Mozambique, South Africa and Spain.

Evaluation of radiological capacity and usage in paediatric TB diagnosis: A mixed-method protocol of a comparative study in Mozambique, South Africa and Spain.

Fuente:Plos One

Tipo de trabajo:Estudio multicéntrico

Extracto: It will inform clinicians and radiologists on best practices and means to optimise the use of radiological technology in paediatric TB management.

Cita:PLoS One 2024; 19 (4) : e0299293.

Autor/es:Munyangaju, Isabelle (a)
José, Benedita (b)

institución:(a) Barcelona Institute for Global Health, Barcelona, Catalonia, Spain.
(b) Medicine and Translational Research Department, University of Barcelona, Barcelona, Spain.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1371/journal.pone.0299293

Pharmacometric in silico studies used to facilitate a national dose standardisation process in neonatology - application to amikacin.

Pharmacometric in silico studies used to facilitate a national dose standardisation process in neonatology - application to amikacin.

Fuente:Swiss Medical Weekly

Extracto: Pharmacometric in silico studies using high-quality real-world demographic data can provide a scientific rationale for national paediatric dose optimisation. This may increase clinical acceptance of fine-tuned standardised dosing recommendations and support their implementation, including in vulnerable subpopulations.

Cita:Swiss Med Wkly 2024 Apr 8; 154 : 3632.

Autor/es:Gotta, Verena (a)
Bielicki, Julia Anna (b)

institución:(a) SwissPedDose/SwissPedNet collaboration expert team, Zürich/Basel/Lausanne, Switzerland.
(b) Pediatric Pharmacology and Pharmacometrics, University of Basel Children's Hospital, Basel, Switzerland.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.57187/s.3632

Antiviral cellular therapy for enhancing T-cell reconstitution before or after hematopoietic stem cell transplantation (ACES): a two-arm, open label phase II interventional trial of pediatric patients with risk factor assessment.

Antiviral cellular therapy for enhancing T-cell reconstitution before or after hematopoietic stem cell transplantation (ACES): a two-arm, open label phase II interventional trial of pediatric patients with risk factor assessment.

Fuente:Nature Communications

Extracto: This study highlights key clinical factors that impact response to VSTs and demonstrates the feasibility and efficacy of this therapy in pediatric HSCT.

Cita:Nat Commun 2024 Apr 18; 15 (1) : 3258.

Autor/es:Keller, Michael D (a)
Hanley, Patrick J (b)

institución:(a) Center for Cancer & Immunology Research, Children's National Hospital, Washington, DC, USA.
(b) Division of Allergy and Immunology, Children's National Hospital, Washington, DC, USA.

Conflicto:C.M.B. has filed patents in the arena of cell therapies, was a scientific co-founder of Mana Therapeutics and Catamaran Bio, is on the Board of Directors of Cabaletta Bio and holds stock in Repertoire Immune Medicine and Neximmune all of which are developing cell therapies for cancer or immune mediated disorders. In addition, she serves on the drug safety monitoring... boards (DSMB) for SOBI and on the SAB of Minovia TX Ltd. M.A.P. is on Advisory boards—Novartis, Gentibio, Bluebird, Vertex, Medexus, Equillium; and Study Support—Adaptive, Miltenyi. P.J.H. was a Co-founder and Board of Directors: Mana Therapeutics and is on the Scientific Advisory Boards for Cellevolve, Cellenkos, Capsida, MicrofluidX, Discovery Life Sciences M.R.V. is on the Ad boards for Qihan, Sanofi, the Adjudication board for Allovir, and DSMBs for Forge and Omeros. P.S. is a consultant for Sobi BJD is an Ad hoc consultant for Sobi and on the DSMB for Orchard Therapeutics S.C. is an Ad hoc advisory board member of Pharming, SOBI, X4 therapeutics and Electra therapeutics T.C.Q. is on the speakers bureau for Jazz Pharmaceuticals and Alexion Pharmaceuticals. C.C.D. is a consultant for Alexion Pharmaceuticals and Jazz Pharmaceuticals. M.D.K. is an author for Elsevier (Uptodate). All other authors have no competing interests to disclose.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1038/s41467-024-47057-2

Epidemiological study of pediatric nutritional deficiencies: an analysis from the global burden of disease study 2019.

Epidemiological study of pediatric nutritional deficiencies: an analysis from the global burden of disease study 2019.

Fuente:Nutrition Journal

Extracto: Pediatric ND remains a major public health challenge, especially in areas with low SDI. Therefore, primary healthcare services in developing countries should be improved, and effective measures, such as enhanced pre-school education, strengthened nutritional support, and early and aggressive treatment, need to be developed.

Claves:Children, Epidemiology, Global burden of Disease (GBD), Joinpoint regression analysis, Nutritional deficiencies

Cita:Nutr J 2024 Apr 18; 23 (1) : 44.

Autor/es:Mao, Chenhan (a)
Shen, Zhuyang (b)

institución:(a) Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing, Jiangsu, China.
(b) Jiangsu Province Academy of Traditional Chinese Medicine, Nanjing, Jiangsu, China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12937-024-00945-1

Multidrug-resistant pathogens and ventilator-associated pneumonia in critically ill COVID-19 and non-COVID-19 patients: a prospective observational monocentric comparative study.

Multidrug-resistant pathogens and ventilator-associated pneumonia in critically ill COVID-19 and non-COVID-19 patients: a prospective observational monocentric comparative study.

Fuente:Respiratory Research

Tipo de trabajo:Estudio de cohortes

Extracto: COVID-19 patients with VAP appear to have a significantly higher ICU and in-hospital mortality risk regardless of the presence of MDR and DTR pathogens. Tracheostomy and a shorter duration of mechanical ventilation appear to be associated with better outcomes.

Claves:Antimicrobial resistance, COVID-19, Critical care, Difficult to treat organisms, Multidrug resistant organisms, Ventilator-acquired pneumonia

Cita:Respir Res 2024 Apr 18; 25 (1) : 168.

Autor/es:Montrucchio, Giorgia (a)
Balzani, Eleonora (b)

institución:(a) Department of Surgical Sciences, University of Turin, Turin, Italy. giorgiagiuseppina.montrucchio@unito.it.
(b) Department of Anesthesia, Intensive Care and Emergency, Città della Salute e della Scienza Hospital, Turin, Italy. giorgiagiuseppina.montrucchio@unito.it.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12931-024-02779-1

Altered oral microbiome, but normal human papilloma virus prevalence in cartilage-hair hypoplasia patients.

Altered oral microbiome, but normal human papilloma virus prevalence in cartilage-hair hypoplasia patients.

Fuente:Orphanet Journal of Rare Diseases

Extracto: Individuals with CHH exhibit similar prevalence of HPV DNA but different bacterial microbiota on their oral mucosa compared to healthy controls. This may partly explain the previously observed high prevalence of oral diseases in CHH, and regular oral examination is warranted.

Claves:Cartilage-hair hypoplasia, Human papilloma virus, Inborn errors of immunity, Microbiome

Cita:Orphanet J Rare Dis 2024 Apr 18; 19 (1) : 169.

Autor/es:Arponen, Heidi (a)
Vakkilainen, Svetlana (b)

institución:(a) Department of Oral and Maxillofacial Diseases, Helsinki University Hospital Head and Neck Center, University of Helsinki, Haartmaninkatu 1, Helsinki, Finland. heidi.arponen@helsinki.fi.
(b) Pediatric Research Center, Children's Hospital, University of Helsinki, Helsinki University Hospital, Helsinki, Finland. heidi.arponen@helsinki.fi.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s13023-024-03164-3

Exploring adolescent mental health during the COVID-19 crisis - strengths and difficulties.

Exploring adolescent mental health during the COVID-19 crisis - strengths and difficulties.

Fuente:Frontiers in Public Health

Extracto: Our study contributes to understanding the psychosocial impact of the COVID-19 pandemic on German adolescents. Compared to other symptoms, we observed a particular worsening in "Emotional Symptoms" based on our data. Despite the moderate correlation between parental and self-reported evaluations, there appears to be a certain discrepancy in the perception of adolescent quality of life. Therefore, it seems prudent to assess both the external and self-reported evaluations and amalgamate the results from both parties to obtain a comprehensive problem profile of the individual. These findings underscore the importance of using country-specific cutoff values and reaffirm the utility of the SDQ as a valuable assessment tool, even within the unique circumstances posed by a pandemic.

Claves:COVID-19 pandemic, SDQ-questionnaire, adolescents, crisis, mental health, mental health assessment

Cita:Front Public Health 2024; 12 : 1357766.

Autor/es:Loy, Johanna K (a)
Klam, Janina (b)

institución:(a) Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.
(b) Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.

Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. The author(s) declared that they were an editorial board member of Frontiers, at the time of submission. This had no impact on the peer review process and the final decision.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3389/fpubh.2024.1357766

Enhanced peer-group strategies to support the prevention of mother-to-child HIV transmission leads to increased retention in care in Uganda: A randomized controlled trial.

Enhanced peer-group strategies to support the prevention of mother-to-child HIV transmission leads to increased retention in care in Uganda: A randomized controlled trial.

Fuente:Plos One

Tipo de trabajo:Estudio aleatorizado y controlado

Extracto: Our findings suggest that programmatic interventions that provide group support, community-based ART distribution, and income-generation activities may contribute to retention in PMTCT care, HIV-free survival of children born to women living with HIV, and ultimately, to the elimination of mother-to-child HIV transmission (EMTCT). TRIAL REGISTRATION: NCT02515370 (04/08/2015) on ClinicalTrials.gov.

Cita:PLoS One 2024; 19 (4) : e0297652.

Autor/es:Amone, Alexander (a)
Gabagaya, Grace (b)

institución:(a) Makerere University-Johns Hopkins University Research Collaboration, Kampala, Uganda.
(b) Makerere University-Johns Hopkins University Research Collaboration, Kampala, Uganda.

Conflicto:PM received funding from NIH/Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) grant # IR01HD080476-01.

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1371/journal.pone.0297652

How different attributes are weighted in professionals' decision-making in Pediatric Dentistry-a protocol for guiding discrete choice experiment focused on shortening the evidence-based practice implementation for dental care.

How different attributes are weighted in professionals' decision-making in Pediatric Dentistry-a protocol for guiding discrete choice experiment focused on shortening the evidence-based practice implementation for dental care.

Fuente:Bmc Oral Health

Tipo de trabajo:Estudio clínico aleatorizado

Extracto: TRIAL REGISTRATION: https://osf.io/bhncv .

Claves:Dentistry, Discrete choice experiments, Preference

Cita:BMC Oral Health 2024 Apr 19; 24 (1) : 474.

Autor/es:Machado, Gabriela Manco (a)
Luca, Ana Clara Falabello (b)

institución:(a) Orthodontics and Pediatric Dentistry Department, Faculty of Dentistry, University of São Paulo, Av. Prof. Lineu Prestes, 2227 - Butantã, São Paulo, SP, 05508-000, Brazil.
(b) Orthodontics and Pediatric Dentistry Department, Faculty of Dentistry, University of São Paulo, Av. Prof. Lineu Prestes, 2227 - Butantã, São Paulo, SP, 05508-000, Brazil.

Conflicto:Prof. Mariana M. Braga is a Senior Editor, Prof. Tatiana Pereira-Cenci and Prof. Tathiane L. Lenzi are Associate Editors at BMC Oral Health. Besides, Prof. Paulo Nadanovsky is Editorial Advisor for the same journal. Nevertheless, none of them will take part of the editorial process related to this manuscript. Other authors do not have any competing interests.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12903-024-04090-3

Evaluating a web-based training curriculum for disseminating best practices for the care of newborns with neonatal opioid withdrawal syndrome in a rural hospital, the NOWS-NM Program.

Evaluating a web-based training curriculum for disseminating best practices for the care of newborns with neonatal opioid withdrawal syndrome in a rural hospital, the NOWS-NM Program.

Fuente:Bmc Pediatrics

Extracto: This curriculum demonstrated positive impacts on NOWS knowledge and care practices. Incorporating focus on core concepts of trauma-informed care and self-regulation in future iterations of the curriculum may strengthen the opportunity to change attitudes and address the needs expressed by participants and improve care of families and babies with NOWS.

Claves:Curriculum, Neonatal opioid withdrawal syndrome, Provider, Rural, Trauma-informed care

Cita:BMC Pediatr 2024 Apr 19; 24 (1) : 258.

Autor/es:Pratt-Chavez, Heather (a)
Rishel Brakey, Heidi (b)

institución:(a) School of Medicine, Department of Pediatrics, University of New Mexico, MSC10 5590, Albuquerque, NM, 87131, USA. hpchavez@salud.unm.edu.
(b) Clinical & Translational Science Center, University of New Mexico, MSC08 4635, Albuquerque, NM, 87131, USA.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12887-024-04710-5

Home care needs assessment among caregivers of children and adolescents with osteogenesis imperfecta: a cross-sectional study.

Fuente:Bmc Primary Care

Tipo de trabajo:Orientaciones y guía

Extracto: The findings of this study suggest that future scientific research and nursing guidance should focus on OI patients' physical training, medication management, pain relief, fracture prevention, and treatment. In addition, caregivers of patients with poor self-care ability should receive special attention in the development of interventions. This study can help with addressing the unmet home care needs of caregivers of children and adolescents with OI. It is vital to develop a personalized intervention plan based on patients' self-care ability.

Claves:Adolescents, Children, China, Home Care needs, Osteogenesis Imperfecta

Cita:BMC Prim Care 2024 Apr 19; 25 (1) : 119.

Autor/es:Wang, Xinyi (a)
Li, Yuqing (b)

institución:(a) School of Nursing, Shandong First Medical University & Shandong Academy of Medical Sciences, No.6699 Qingdao Road, Huaiyin District, Jinan, Shandong Province, 250117, China.
(b) Department of Pediatric Orthopaedics, Shandong Provincial Hospital Affiliated to Shandong First Medical University& Shandong Academy of Medical Sciences, No.324 Five Weft Seven Road, Huaiyin District, Jinan, Shandong Province, 250021, China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12875-024-02367-8

Early predictors of delayed radiographic resolution of lobar pneumonia caused by Mycoplasma pneumoniae in children: a retrospective study in China.

Early predictors of delayed radiographic resolution of lobar pneumonia caused by Mycoplasma pneumoniae in children: a retrospective study in China.

Fuente:Bmc Infectious Diseases

Extracto: If patients with lobar pneumonia caused by Mycoplasma pneumoniae have a hospitalization time of ≥ 10.5 days, CRP level of ≥ 25.92 mg/L, and LDH level ≥ 378 U/L, the time of radiographic resolution is highly likely to exceed 8 weeks. Pediatricians must maintain a high level of vigilance for these factors, control the infection as early as possible, strengthen airway management, and follow up closely to avoid complications and sequelae of Mycoplasma pneumoniae pneumonia.

Claves:Mycoplasma pneumoniae, Children, Imaging, Lobar pneumonia

Cita:BMC Infect Dis 2024 Apr 19; 24 (1) : 414.

Autor/es:Zheng, Yu (a)
Mao, Guoshun (b)

institución:(a) Department of Pediatrics, Fu Yang People's Hospital, No.501, Sanqing Road, Yingzhou District, 236000, Fuyang, Anhui Province, China.
(b) Department of Pediatrics, Fu Yang People's Hospital, No.501, Sanqing Road, Yingzhou District, 236000, Fuyang, Anhui Province, China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12879-024-09289-x

NR1H4 disease: rapidly progressing neonatal intrahepatic cholestasis and early death.

NR1H4 disease: rapidly progressing neonatal intrahepatic cholestasis and early death.

Fuente:Orphanet Journal of Rare Diseases

Tipo de trabajo:Revisión

Extracto: We identified three newly-diagnosed patients and five novel mutations. NR1H4-related PFIC typically cause progressive disease and early death. LT may be the only lifesaving therapy leading to cure.

Claves:NR1H4, Liver transplantation, low-γ-glutamyl transferase (GGT) cholestasis

Cita:Orphanet J Rare Dis 2024 Apr 19; 19 (1) : 171.

Autor/es:Li, Zhong-Die (a)
Li, Yu-Chuan (b)

institución:(a) The Center for Pediatric Liver Diseases, Children's Hospital of Fudan University, No. 399 Wanyuan Road, Minhang District, 201102, Shanghai, China.
(b) The Center for Pediatric Liver Diseases, Children's Hospital of Fudan University, No. 399 Wanyuan Road, Minhang District, 201102, Shanghai, China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s13023-024-03166-1

Experiences of physical and emotional intimate partner violence during the COVID-19 pandemic: a comparison of prepandemic and pandemic data in a longitudinal study of Australian mothers.

Experiences of physical and emotional intimate partner violence during the COVID-19 pandemic: a comparison of prepandemic and pandemic data in a longitudinal study of Australian mothers.

Fuente:Bmj Open

Extracto: Findings suggest that the spike in IPV-related crime statistics following the onset of the pandemic (typically incidents of physical violence) is the tip of the iceberg for women's IPV experiences. There is a need to increase the capacity of health practitioners to recognise emotional as well as physical IPV, and IPV ought to be considered where women present with mental health problems.

Claves:COVID-19, MENTAL HEALTH, Primary Care

Cita:BMJ Open 2024 Apr 19; 14 (4) : e081382.

Autor/es:FitzPatrick, Kelly M (a)
Brown, Stephanie J (b)

institución:(a) Intergenerational Health, Murdoch Childrens Research Institute, Parkville, Victoria, Australia kelly.fitzpatrick@mcri.edu.au.
(b) Intergenerational Health, Murdoch Childrens Research Institute, Parkville, Victoria, Australia.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1136/bmjopen-2023-081382

Employing supervised machine learning algorithms for classification and prediction of anemia among youth girls in Ethiopia.

Employing supervised machine learning algorithms for classification and prediction of anemia among youth girls in Ethiopia.

Fuente:Scientific Reports

Extracto: Therefore, making it potentially valuable as decision-support tools for the relevant stakeholders and giving emphasis for the identified predictors could be an important intervention to halt anemia among youth girls.

Cita:Sci Rep 2024 Apr 20; 14 (1) : 9080.

Autor/es:Zemariam, Alemu Birara (a)
Yimer, Ali (b)

institución:(a) Department of Pediatrics and Child Health Nursing, School of Nursing, College of Medicine and Health Science, Woldia University, Po. Box: 400, Woldia, Ethiopia. alexb7298@gmail.com.
(b) Department of Public Health, School of Public Health, College of Medicine and Health Science, Woldia University, Woldia, Ethiopia.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1038/s41598-024-60027-4

Trends in pediatric prescription-opioid overdoses in U.S. emergency departments from 2008-2020: An epidemiologic study of pediatric opioid overdose ED visits.

Trends in pediatric prescription-opioid overdoses in U.S. emergency departments from 2008-2020: An epidemiologic study of pediatric opioid overdose ED visits.

Fuente:Plos One

Extracto: Prescription-opioid overdose ED visits among U.S. children and adolescents decreased over the past decade until 2019. However, there was a substantial increase in ED visits from 2019 to 2020, suggesting the potential impact due to the then-emerging COVID-19 pandemic. Findings suggest focusing on young children and adolescents to reduce further prescription-opioid overdoses in the United States.

Cita:PLoS One 2024; 19 (4) : e0299163.

Autor/es:Lu, Audrey (a)
Armstrong, Megan (b)

institución:(a) The Abigail Wexner Research Institute at Nationwide Children's Hospital, Center for Pediatric Trauma Research, Columbus, OH, United States of America.
(b) The Abigail Wexner Research Institute at Nationwide Children's Hospital, Center for Pediatric Trauma Research, Columbus, OH, United States of America.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1371/journal.pone.0299163

Effects of oropharyngeal administration of own mother's milk on oral microbial colonization in very low birth weight infants fed by gastric tube: A randomized controlled trial.

Fuente:Immunity, Inflammation and Disease

Tipo de trabajo:Estudio aleatorizado y controlado

Extracto: Firmicutes had replaced Proteobacteria as the predominant phylum.

Claves:human milk, microbiota, oropharynx, very low birth weight infants

Cita:Immun Inflamm Dis 2024 Apr; 12 (4) : e1247.

Autor/es:Liu, Jie (a)
Zhang, Xiyang (b)

institución:(a) Department of Traditional Chinese Medicine Gynecology, Pediatric Neurorehabilitation Department, Department of Neonatology, Shenzhen Maternity and Child Healthcare Hospital, Shenzhen, China.
(b) Department of Traditional Chinese Medicine Gynecology, Pediatric Neurorehabilitation Department, Department of Neonatology, Shenzhen Maternity and Child Healthcare Hospital, Shenzhen, China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe impreso

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1002/iid3.1247

Feasibility and reliability of fetal two dimensional speckle tracking echocardiography at 16 weeks gestational age: A pilot study.

Feasibility and reliability of fetal two dimensional speckle tracking echocardiography at 16 weeks gestational age: A pilot study.

Fuente:Plos One

Tipo de trabajo:Estudio de cohortes

Extracto: Our findings demonstrate that fetal 2D-STE analysis at 16 weeks gestational age is feasible when adhering to a strict protocol. However, further improvements are necessary to enhance the inter- and intra-operator reliability of 2D-STE at this gestational age.

Cita:PLoS One 2024; 19 (4) : e0302123.

Autor/es:Nichting, Thomas J (a)
van Lier, Zoé A (b)

institución:(a) Department of Gynaecology and Obstetrics, Máxima MC, Veldhoven, The Netherlands.
(b) Department of Electrical Engineering, Eindhoven University of Technology, Eindhoven, The Netherlands.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1371/journal.pone.0302123

Case report: EBV-related eye orbits and sinuses lymphohistiocytic infiltration responsive to rituximab in a patient with X lymphoproliferative syndrome type 1.

Case report: EBV-related eye orbits and sinuses lymphohistiocytic infiltration responsive to rituximab in a patient with X lymphoproliferative syndrome type 1.

Fuente:Frontiers in Immunology

Extracto: We described an unusual presentation of incomplete HLH in a patient affected with XLP1: an EBV-driven infiltration of the orbits and paranasal sinuses. This led us to a challenging differential diagnosis of lymphoma-associated hemophagocytic syndrome, which can be frequently observed in patients with XLP1. Considering the extremely poor prognosis of this clinical finding, we sought for a prompt diagnosis and managed to obtain it and to immediately establish the right treatment on the basis of the pathological finding.

Claves:EBV, SH2D1A, X lymphoproliferative syndrome type 1, eye lymphohistiocytic infiltration, rituximab

Cita:Front Immunol 2024; 15 : 1370991.

Autor/es:Giardino, Giuliana (a)
Lanni, Vittoria (b)

institución:(a) Department of Translational Medical Sciences, Pediatric Section, Federico II University of Naples, Naples, Italy.
(b) Department of Neurosciences, Reproductive Sciences and Dentistry, University of Naples Federico II, Naples, Italy.

Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3389/fimmu.2024.1370991

Longitudinal microstructural changes in 18 amygdala nuclei resonate with cortical circuits and phenomics.

Longitudinal microstructural changes in 18 amygdala nuclei resonate with cortical circuits and phenomics.

Fuente:Communications Biology

Extracto: The obtained structural plasticity findings motivate hypotheses about the specific functions of distinct amygdala nuclei in humans.

Cita:Commun Biol 2024 Apr 18; 7 (1) : 477.

Autor/es:Ghanem, Karam (a)
Saltoun, Karin (b)

institución:(a) The Neuro - Montreal Neurological Institute (MNI), McConnell Brain Imaging Centre, Department of Biomedical Engineering, Faculty of Medicine, School of Computer Science, McGill University, Montreal, Canada. ghanemkaram12@gmail.com.
(b) Mila - Quebec Artificial Intelligence Institute, Montreal, QC, Canada. ghanemkaram12@gmail.com.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1038/s42003-024-06187-5