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SIIC selecciona textos completos de calidad y de reciente publicación en fuentes prestigiosas del mundo
indizadas por SIIC Data Bases, capturadas en las mismas colecciones o en diversas bases especializadas.
La creciente cantidad de artículos con Acceso Abierto (Open
Access) amplía la oferta de lectura pero a su vez también, entre
tanta abundancia, complica al lector en su encuentro con los estudios
fundamentales. Para facilitarlo, profesionales biomédicos de SIIC
consultan diariamente una profusa cantidad de documentos que nutrirán
Textos completos autorizados (TCA).
Las citas de la sección TCA enlazan de manera legal, autorizada y
gratuita con los textos completos (full text) publicados en
los sitios oficiales de sus respectivas fuentes.
SIIC creó, produjo y opera con exclusividad el software TCA para la
interpretación de los diversos campos documentales que integran la
estructura de un estudio: especialidad, modalidad del estudio,
fuente, fechas de publicación y selección, definición de la fuente,
limitaciones de consulta, resumen en castellano, etc.
Si bien la mayoría de los textos seleccionados corresponden a
artículos originales, revisiones y guías, los lectores también
encontrarán comentarios, entrevistas, notas periodísticas, cartas a
autores u otros textos precursores de debates o aclaratorios.
Sociedad Iberoamericana de Información Científica (SIIC) selects
complete quality-full texts which have been recently published in
renowned sources worldwide and are indexed by SIIC Data
Bases.
The increasing number of Open Access articles widens the reading offer
but, also, such myriad complicates the readers search of fundamental
articles. To facilitate this, SIIC biomedical professionals daily
consult a profuse amount of documents that will feed
Authorized Full Texts (TCA, Spanish acronym).
The citations of the AFT section link legally, authorized and free of
charge with the full texts published in the official web sites of
their corresponding sources.
SIIC created, produced and handles the AFT software that deciphers
the various documentary fields that form part of the structure of a
study: specialty, study style, source, publication and selection
dates, source definition, query limitations, summary in Spanish,
etc.
While most of the selected texts belong to original articles,
reviews, and guidelines, readers will also find commentaries,
interviews, journalistic reports, letters to authors or other texts
that may lead to discussions or clarifications.
A structural and mechanistic model for BSEP dysfunction in PFIC2 cholestatic disease.
A structural and mechanistic model for BSEP dysfunction in PFIC2 cholestatic disease.
Fuente:Communications Biology
Extracto:
These findings suggest potential strategies for identifying
mechanism-based small molecule correctors to address BSEP trafficking defects and
advance novel therapies for PFIC2 and other cholestatic diseases.
Cita:Commun Biol 2025 Apr 7; 8 (1) : 531.
Autor/es:Gruget, Clémence (a) Reddy, Bharat G (b)
institución:(a) Massachusetts Institute of Technology, Cambridge, MA, USA. (b) Rectify Pharmaceuticals, Cambridge, MA, USA.
Conflicto:Competing interests: The authors declare the following competing interests: J.M.M. and B.G.R. are employees of Rectify Pharmaceuticals and receive salary and equity compensation. C.G. declares no competing interests.
Genotype-phenotype correlation in a cohort of pediatric patients with autoinflammatory diseases carrying NOD2 variants.
Genotype-phenotype correlation in a cohort of pediatric patients with autoinflammatory diseases carrying NOD2 variants.
Fuente:Frontiers in Immunology
Extracto:
This is the first study to evaluate genotypic/phenotypic
characteristics of children with systemic autoinflammatory disease and NOD2
variants. The results, albeit preliminary and affected by the sample size, do not
allow a definitive conclusion on a monogenic disease caused by mutation in NOD2,
with the obvious exception of Blau syndrome. Variants in the NOD domain seem to
be associated with a more homogenous clinical phenotype.
Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
The impact of rare diseases on the quality of life in paediatric patients: current status.
The impact of rare diseases on the quality of life in paediatric patients: current status.
Fuente:Frontiers in Public Health
Extracto:
It stresses the pivotal
role each group plays in improving the diagnosis, treatment, and overall quality
of life for paediatric patients with rare diseases.
Claves:disease burden, paediatrics, prevalence, quality of life, rare diseases
Cita:Front Public Health 2025; 13 : 1531583.
Autor/es:Dumbuya, John Sieh (a) Zeng, Cizheng (b)
institución:(a) Department of Paediatrics, Affiliated Hospital of Guangdong Medical University, Zhanjiang, China. (b) Department of Paediatrics, Affiliated Hospital of Guangdong Medical University, Zhanjiang, China.
Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Children's birth weight and the risk of general obesity and central obesity in primary school children: a 4-year longitudinal study.
Children's birth weight and the risk of general obesity and central obesity in primary school children: a 4-year longitudinal study.
Fuente:Frontiers in Public Health
Extracto:
Higher levels of BW (≥ 3.5 kg) were associated with an increased risk of OB in
children, but not central OB. The results can support public health specialists
for future research and improvement of strategies for childhood obesity
prevention.
Claves:birth weight, central obesity, childhood, general obesity, overweight
Cita:Front Public Health 2025; 13 : 1469226.
Autor/es:Lin, Yi (a) Rankin, Richard (b)
institución:(a) Center for Health Economics, Faculty of Humanities and Social Sciences, University of Nottingham, Ningbo, Zhejiang Province, China. (b) Department of Mathematical Sciences, Faculty of Science and Engineering, University of Nottingham, Ningbo, Zhejiang Province, China.
Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
A family study of dentinogenesis imperfecta shields type II caused by a novel DSPP mutation and investigations on the isolated stem cells from human exfoliated deciduous teeth.
A family study of dentinogenesis imperfecta shields type II caused by a novel DSPP mutation and investigations on the isolated stem cells from human exfoliated deciduous teeth.
Fuente:Bmc Oral Health
Extracto:
This study identified a novel frameshift mutation, DSPP
c.2695delA.N899fs, in a DGI-II family and demonstrated its impact on SHED
proliferation, migration, and mineralization. The findings demonstrated that this
novel variant disturbs dentinal characteristics and cell behavior of SHED.
Claves:DSPP gene, Dentinogenesis imperfecta (DGI), Frameshift mutation, Shields type-II, Stem cells from human exfoliated deciduous teeth (SHED)
Cita:BMC Oral Health 2025 Apr 7; 25 (1) : 503.
Autor/es:Gao, Qianhua (a) Yue, Ning (b)
institución:(a) Department of Stomatology, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, No.32, Section 2, The First Ring Road West, Chengdu, 610072, Sichuan, China. (b) Department of Stomatology, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, No.32, Section 2, The First Ring Road West, Chengdu, 610072, Sichuan, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Adaptations of an online cognitive-behavioral therapy intervention for binge type eating disorders in publicly-insured and uninsured adults: a pilot study.
Adaptations of an online cognitive-behavioral therapy intervention for binge type eating disorders in publicly-insured and uninsured adults: a pilot study.
Fuente:Bmc Public Health
Tipo de trabajo:Revisión
Extracto:
Overall, user feedback is critical to informing adaptations to the
original EBI so that the intervention can be appropriately tailored to the needs
of this underserved population, which ultimately has high potential to address
critical barriers to ED treatment. TRIAL REGISTRATION: This study was reviewed
and approved by the Institutional Review Board (IRB) at the University
California, San Francisco (IRB #22-35936) and the IRB at Washington University in
St. Louis (IRB ID 202304167).
Claves:Binge eating disorder, Bulimia nervosa, Cognitive behavioral therapy, Digital intervention, Eating disorders, Public insurance, mHealth
Cita:BMC Public Health 2025 Apr 7; 25 (1) : 1296.
Autor/es:Vendlinski, Siena S (a) Laboe, Agatha A (b)
institución:(a) Department of Pediatrics, University of California, San Francisco, San Francisco, CA, USA. (b) Department of Psychiatry and Behavioral Sciences, University of California, San Francisco, San Francisco, CA, USA.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Characterizing lupus in African American children in Southern United States.
Characterizing lupus in African American children in Southern United States.
Fuente:Pediatric Rheumatology Online Journal
Tipo de trabajo:Revisión
Extracto:
Compared to previously described multiethnic
cohorts of cSLE, this predominantly AA patient population in the Southern United
States has significantly higher disease activity and greater damage accrual.
Social risk factors for this population include a higher SVI, longer distance
from an academic pediatric rheumatology center, and having Medicaid insurance.
The effect of these factors on disparity of disease outcomes needs to be further
explored with larger cohorts.
Autor/es:Winstead, Taylor B (a) Hagwood, Spencer (b)
institución:(a) School of Medicine, The University of Mississippi Medical Center, Jackson, MS, USA. (b) School of Medicine, The University of Mississippi Medical Center, Jackson, MS, USA.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Early treatment and PD1 inhibition enhance HIV-specific functionality of follicular CD8+ T cells.
Early treatment and PD1 inhibition enhance HIV-specific functionality of follicular CD8+ T cells.
Fuente:Jci Insight
Extracto:
These findings underscore the
pivotal role of follicular CD8+ T cells in anti-HIV responses and support
investigating targeted cure strategies, such as anti-PD1 therapy, especially in
individuals initiating treatment during acute infection.
Claves:AIDS/HIV, Adaptive immunity, Immunology, T cells
Cita:JCI Insight 2025 Apr 8; 10 (7)
Autor/es:Rueger, Susanne (a) Gruener, Eva (b)
institución:(a) Department of Infectious Diseases, Department of Medicine IV, LMU University Hospital, LMU Munich, Munich, Germany. (b) German Centre for Infection Research (DZIF), partner site Munich, Germany.
Unique and shared transcriptomic signatures underlying localized scleroderma pathogenesis identified using interpretable machine learning.
Unique and shared transcriptomic signatures underlying localized scleroderma pathogenesis identified using interpretable machine learning.
Fuente:Jci Insight
Extracto:
Our analyses recapitulate known drivers of LS pathology
and identify cellular signaling modules that stratify LS subtypes and define a
shared signaling axis with SSc.
Native kidney and graft survival in a cohort of Egyptian children with nephropathic cystinosis: national referral center experience.
Native kidney and graft survival in a cohort of Egyptian children with nephropathic cystinosis: national referral center experience.
Fuente:Italian Journal of Pediatrics
Extracto:
Improvement in the awareness and the accessibility to diagnosis over
years, early sibling screening, and kidney transplantation have a significant
impact on the survival of both patients and kidney in children with nephropathic
cystinosis.
institución:(a) Center of Pediatric Nephrology and Transplantation, Cairo University, Cairo, Egypt. (b) Center of Pediatric Nephrology and Transplantation, Cairo University, Cairo, Egypt. Fatma.atia@kasralainy.edu.eg.
Conflicto:Declarations. Ethics approval and consent to participate: The study was conducted in accordance with the principles outlined in the Declaration of Helsinki. In addition, the institutional review board approved the study procedures [Approval number is N-464–2023]. The confidentiality of all subjects’ data was guaranteed. Consent for publication: As this manuscript does not contain any content that can reveal the patient’s...
nt’s identity, written informed consent was not taken from the patient’s guardians. Competing interests: All Authors declare no conflict of interest.
Embryonal rhabdomyosarcoma at an unusual age and in an atypical site
Embryonal rhabdomyosarcoma at an unusual age and in an atypical site
Fuente:Journal of Medical Case Reports
Tipo de trabajo:Caso clínico
Extracto:
This paper
describes a case of a patient diagnosed with adult rhabdosmyosarcoma at an
uncommon age and in an uncommon site; therefore, it is important to consider
rhabdomyosarcoma in the differential diagnosis of patients given an abnormal
presentation and unexplained findings. Early detection of the disease, which is
difficult with nonspecific symptoms, is crucial for improving outcomes.
Claves:Adult rhabdomyosarcoma, Drug therapy, Embryonal rhabdomyosarcoma, Radiotherapy
Cita:J Med Case Rep 2025 Apr 7; 19 (1) : 164.
Autor/es:Kouli, Ayla (a) Baddoura, Mouna (b)
institución:(a) Faculty of Medicine, Damascus University, Damascus, Syrian Arab Republic. (b) Faculty of Medicine, Damascus University, Damascus, Syrian Arab Republic. baddouramouna630@gmail.com.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Brazilian red propolis as a potential antimicrobial additive in orthodontic primers.
Brazilian red propolis as a potential antimicrobial additive in orthodontic primers.
Fuente:Brazilian Dental Journal
Extracto:
Propolis-modification did not influence the physic-chemical properties of
the orthodontic adhesive.
Cita:Braz Dent J 2025; 36 : e246036.
Autor/es:Pingueiro, João Marcos Spessoto (a) Feres, Murilo Fernando Neuppmann (b)
institución:(a) Dental Research Division, School of Dentistry, Guarulhos University, Guarulhos, São Paulo, Brazil. (b) Dental Research Division, School of Dentistry, Guarulhos University, Guarulhos, São Paulo, Brazil.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Probability of referral to curative dental treatment in a preventive pediatric dentistry program.
Probability of referral to curative dental treatment in a preventive pediatric dentistry program.
Fuente:Brazilian Oral Research
Extracto:
Establishing
personalized follow-up intervals based on individual patient needs is crucial for
maintaining oral health.
Cita:Braz Oral Res 2025; 39 : e039.
Autor/es:Rocha, Lorena Castro (a) Assunção, Cristiane Meira (b)
institución:(a) Universidade Federal de Minas Gerais - UFMG School of Dentistry, Department of Pediatric Dentistry, Belo Horizonte, MG, Brazil. (b) Universidade Federal de Minas Gerais - UFMG School of Dentistry, Department of Pediatric Dentistry, Belo Horizonte, MG, Brazil.
Conflicto:Declaration of Interests: The authors certify that they have no commercial or associative interest that represents a conflict of interest in connection with the manuscript.
Delays in seeking healthcare and its determinants among malaria patients in Ethiopia
Delays in seeking healthcare and its determinants among malaria patients in Ethiopia
Fuente:Plos One
Tipo de trabajo:Revisión sistemática
Extracto:
The pooled prevalence of delays in
seeking healthcare was high, and most of the determinants were modifiable. These
findings underscore the need for targeted interventions to address these barriers
and improve timely access to healthcare for affected populations.
institución:(a) Department of Pediatric and Child Health Nursing, College of Health Science, Debark University, Debark, Ethiopia. (b) Department of Health Systems and Policy, Institute of Public Health, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.
Conflicto:I have read the journal's policy and the authors of this manuscript have no competing interests.
Prevalence, trends, and maternal risk factors of adverse birth outcomes from a hospital-based birth defects surveillance system in Kampala, Uganda, 2015-2022.
Prevalence, trends, and maternal risk factors of adverse birth outcomes from a hospital-based birth defects surveillance system in Kampala, Uganda, 2015-2022.
Fuente:Bmc Pregnancy and Childbirth
Extracto:
Young maternal age, maternal HIV,
and late or no ANC attendance were associated with ABO. Childbearing in the ages
25-34, preventing HIV in women, and supporting early and frequent ANC attendance
are important in improving birth outcomes.
Claves:Adverse birth outcomes, Low birth weight, Preterm birth, Small for gestational age, Stillbirth
Autor/es:Kusolo, Ronald (a) Mumpe-Mwanja, Daniel (b)
institución:(a) Makerere University- Johns Hopkins University Research Collaboration, Kampala, Uganda. rkusolo@musph.ac.ug. (b) Department of Epidemiology and Biostatistics, School of Public Health, Makerere University, Kampala, Uganda. rkusolo@musph.ac.ug.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Comparative effectiveness of Tuina therapy versus manual physical therapy for knee osteoarthritis: a randomized controlled trial.
Comparative effectiveness of Tuina therapy versus manual physical therapy for knee osteoarthritis: a randomized controlled trial.
Fuente:Bmc Complementary Medicine and Therapies
Tipo de trabajo:Estudio aleatorizado y controlado
Extracto:
Tuina
produced beneficial effectiveness similar to mPT in treating KOA. TRIAL
REGISTRATION: NCT03966248, Registered on 29/05/2019, ClinicalTrials.gov.
institución:(a) Acupuncture and Moxibustion Department, Beijing University of Chinese Medicine, Beijing, China. (b) School of Medical Technology, Tianjin University of Traditional Chinese Medicine, Beijing, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Creation and evaluation of an educational escape room in paediatric dentistry.
Creation and evaluation of an educational escape room in paediatric dentistry.
Fuente:Bmc Medical Education
Tipo de trabajo:Revisión
Extracto:
This study highlights the potential of
educational escape games as an innovative and effective pedagogical tool in
paediatric dentistry, serving as a valuable supplementary strategy to diversify
instruction and enhance active learning in dental education.
institución:(a) Department of Paediatric Dentistry, Faculty of Dental Surgery, Paris Cité University, Paris, France. sandrella.hamdan@u-paris.fr. (b) EA732, Paris Cité University, Paris, France. sandrella.hamdan@u-paris.fr.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Digital therapeutics approach for young children with myopia using SAT-001 (DAYS): study protocol for a randomized controlled trial.
Digital therapeutics approach for young children with myopia using SAT-001 (DAYS): study protocol for a randomized controlled trial.
Fuente:Trials
Tipo de trabajo:Estudio aleatorizado y controlado
Extracto:
TRIAL
REGISTRATION: ClinicalTrials.gov: NCT06344572 ; date of registration: April 12,
2024 (retrospectively registered).
Claves:Trials guidance: pediatric myopia, Digital therapeutics, Randomized controlled trial (RCT), SAT-001, Software as a medical device (SaMD)
Cita:Trials 2025 Apr 8; 26 (1) : 128.
Autor/es:Paik, Hae Jung (a) Lee, Byung Joo (b)
institución:(a) Department of Ophthalmology, Gachon University Gil Medical Center, Incheon, Republic of Korea. hjpaik@gilhospital.com. (b) Department of Ophthalmology, Asan Medical Center, Seoul, Republic of Korea.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Bacterial infection in patients with juvenile systemic lupus erythematosus and fever.
Bacterial infection in patients with juvenile systemic lupus erythematosus and fever.
Fuente:Pediatric Rheumatology Online Journal
Extracto:
Bacterial infection was detected in 17% of JSLE patients with fever.
Procalcitonin > 0.9 ng/mL is a critical marker for identifying bacterial
infection. NLR, PLR, ESR/CRP ratio, LC4R, and ferritin require further
investigation to establish definitive cut-off values for differentiating
bacterial infections from other infections or disease activity. Individual
patient evaluation remains the recommended approach for diagnosis.
Autor/es:Gómez-Urrego, José Fernando (a) Yepes-Madrid, Nathalie (b)
institución:(a) Universidad Libre Seccional Cali, Cali, Valle del Cauca, Colombia. josef.gomezu@unilibre.edu.co. (b) Fundación Clínica Infantil Club Noel, Cali, Colombia. josef.gomezu@unilibre.edu.co.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
