Newborn Screening for 6 Lysosomal Storage Disorders in China.

Newborn Screening for 6 Lysosomal Storage Disorders in China.

Fuente:Jama Network Open

Tipo de trabajo:Estudio de cohortes

Extracto: AND RELEVANCE: In this study, the combined birth prevalence of the 6 LSDs in Shanghai was remarkably high. MS/MS-based newborn screening, combined with biochemical and molecular genetic analysis, successfully identified and characterized newborns who were screen-positive, which may assist with parental counseling and management decisions.

Cita:JAMA Netw Open 2024 May 1; 7 (5) : e2410754.

Autor/es:Chang, Siyu (a)
Zhan, Xia (b)

institución:(a) Department of Pediatric Endocrinology and Genetics, Xinhua Hospital, Shanghai Institute for Pediatric Research, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
(b) Department of Pediatric Endocrinology and Genetics, Xinhua Hospital, Shanghai Institute for Pediatric Research, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Conflicto:Conflict of Interest Disclosures: Dr Maegawa reported receiving grants from the National Institutes of Health, Takeda Pharmaceuticals, JCR Pharmaceuticals Co, Sanofi Inc, and Freeline Therapeutics and consulting fees from Lysosomal and Rare Disorders Research and Treatment Center during the conduct of the study. No other disclosures were reported.

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1001/jamanetworkopen.2024.10754

Vitamin K Status Based on K1, MK-4, MK-7, and Undercarboxylated Prothrombin Levels in Adolescent and Adult Patients with Cystic Fibrosis: A Cross-Sectional Study.

Vitamin K Status Based on K1, MK-4, MK-7, and Undercarboxylated Prothrombin Levels in Adolescent and Adult Patients with Cystic Fibrosis: A Cross-Sectional Study.

Fuente:Nutrients

Extracto: There do not seem to be any good clinical predictive factors for vitamin K status.

Claves:cystic fibrosis, gastroenterology, liquid chromatography, pancreatic insufficiency, vitamin K1, vitamin K2

Cita:Nutrients 2024 Apr 29; 16 (9)

Autor/es:Krzyżanowska-Jankowska, Patrycja (a)
Nowak, Jan (b)

institución:(a) Department of Pediatric Gastroenterology and Metabolic Diseases, Poznan University of Medical Sciences, Szpitalna Street 27/33, 60-572 Poznan, Poland.
(b) Department of Pediatric Gastroenterology and Metabolic Diseases, Poznan University of Medical Sciences, Szpitalna Street 27/33, 60-572 Poznan, Poland.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3390/nu16091337

Breastfeeding, Gestational Diabetes Mellitus, Size at Birth and Overweight/Obesity in Early Childhood.

Fuente:Nutrients

Extracto: Conclusions: Initiating and prolonging breastfeeding would reduce the risk of overweight/obesity in early childhood, and LGA infants and infants born to mothers with GDM would experience greater benefits.

Claves:breastfeeding, early childhood, gestational diabetes mellitus, overweight/obesity, size at birth

Cita:Nutrients 2024 Apr 30; 16 (9)

Autor/es:Huang, Ye (a)
Zhang, Libi (b)

institución:(a) Department of Public Health and Department of Anesthesiology, Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou 310009, China.
(b) Department of Epidemiology & Health Statistics, School of Public Health, School of Medicine, Zhejiang University, Hangzhou 310058, China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3390/nu16091351

Clinical variables influencing the severity of diabetes ketoacidosis.

Clinical variables influencing the severity of diabetes ketoacidosis.

Fuente:Saudi Medical Journal

Tipo de trabajo:Revisión

Extracto: Diabetes ketoacidosis was observed to occur more frequently among males in middle childhood with seasonal variations. Furthermore, the severity of DKA was associated with lower economic status, early adolescence, and the presence of hypernatremia.

Claves:Type 1 diabetes, children, clinical, ketoacidosis, presentation, severity

Cita:Saudi Med J 2024 May; 45 (5) : 502-509.

Autor/es:Alhamdani, Yara F (a)
Almadfaa, Lojain O (b)

institución:(a) From the Department of Pediatrics, Faculty of Medicine, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia.
(b) From the Department of Pediatrics, Faculty of Medicine, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia.

Formato:Informe impreso

Idioma:Inglés

País de fuente:Arabia Saudí

Sitio web:http://dx.doi.org/10.15537/smj.2024.45.4.20240058

Endocrine features of Prader-Willi syndrome

Endocrine features of Prader-Willi syndrome

Fuente:Frontiers in Endocrinology

Tipo de trabajo:Revisión

Extracto: We will look at topics such as neonatal anthropometry, thyroid issues, adrenal problems, hypogonadism, bone metabolism abnormalities, metabolic syndrome resulting from severe obesity caused by hyperphagia, deficiencies in the GH/IGF-1 axis, and the corresponding responses to treatment.

Claves:Prader-Willi syndrome (PWS), bone metabolism, genotype-phenotype correlation, growth hormone (GH), hypogonadism, metabolic syndrome, thyroid, type 2 diabetes

Cita:Front Endocrinol (Lausanne) 2024; 15 : 1382583.

Autor/es:Madeo, Simona F (a)
Zagaroli, Luca (b)

institución:(a) Department of Medical and Surgical Sciences for Mother, Children and Adults, Pediatric Unit, University of Modena and Reggio Emilia, Modena, Italy.
(b) Department of Pediatrics, University of L'Aquila, L'Aquila, Italy.

Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. The author(s) declared that they were an editorial board member of Frontiers, at the time of submission. This had no impact on the peer review process and the final decision.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3389/fendo.2024.1382583

Cost-effectiveness of a complex continuum of care intervention targeting women and children: protocol for an economic evaluation of the Bukhali trial in South Africa.

Cost-effectiveness of a complex continuum of care intervention targeting women and children: protocol for an economic evaluation of the Bukhali trial in South Africa.

Fuente:Bmj Open

Tipo de trabajo:Estudio aleatorizado y controlado

Extracto: TRIAL REGISTRATION NUMBER: Pan African Clinical Trials Registry (PACTR201903750173871; https://pactr.samrc.ac.za).

Claves:community child health, diabetes in pregnancy, economics, health economics, obesity, postpartum period

Cita:BMJ Open 2024 May 13; 14 (5) : e080166.

Autor/es:Palmer, Tom (a)
Leiva Granados, Rolando (b)

institución:(a) Institute for Global Health, University College London, London, UK t.palmer@ucl.ac.uk.
(b) Institute for Global Health, University College London, London, UK.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1136/bmjopen-2023-080166

Analgesia for the treatment of acute pancreatitis

Fuente:Bmj Open

Tipo de trabajo:Revisión sistemática

Extracto: They will give healthcare providers a better awareness of the optimal analgesic medication for pain treatment in non-severe, acute pancreatitis.

Claves:Adult gastroenterology, PAIN MANAGEMENT, Paediatric gastroenterology, Pain management, Pancreatic disease

Cita:BMJ Open 2024 May 13; 14 (5) : e081971.

Autor/es:Subramani, Sriya S (a)
Berg, Alaina C (b)

institución:(a) Stead Family Department of Pediatrics, The University of Iowa, Roy J and Lucille A Carver College of Medicine, Iowa City, Iowa, USA.
(b) The University of Iowa, Roy J and Lucille A Carver College of Medicine, Iowa City, Iowa, USA.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1136/bmjopen-2023-081971

Insight into the research history and trends of total anomalous pulmonary venous connection: a bibliometric analysis.

Insight into the research history and trends of total anomalous pulmonary venous connection: a bibliometric analysis.

Fuente:Journal of Cardiothoracic Surgery

Tipo de trabajo:Caso clínico

Extracto: This study conducted a bibliometric analysis to provide a comprehensive overview of TAPVC research. We hope to offer new ideas for promoting development in the field of TAPVC.

Claves:Bibliometrics, CiteSpace, Hot spot, Research progress, Total anomalous pulmonary venous connection, VOSViewer

Cita:J Cardiothorac Surg 2024 May 11; 19 (1) : 285.

Autor/es:Wen, Chen (a)
Shen, Geng (b)

institución:(a) Department of Cardiothoracic Surgery, Shanghai Children's Medical Center, School of Medicine, Shanghai Jiao Tong University, Shanghai, China. wenchen1993@sjtu.edu.cn.
(b) Division of Cardiology, Peking University First Hospital, Beijing, China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s13019-024-02787-8

Urinary L-FABP as an Early Biomarker for Pediatric Acute Kidney Injury Following Cardiac Surgery with Cardiopulmonary Bypass

Urinary L-FABP as an Early Biomarker for Pediatric Acute Kidney Injury Following Cardiac Surgery with Cardiopulmonary Bypass

Fuente:International Journal of Molecular Sciences

Tipo de trabajo:Revisión sistemática

Extracto: Hence, higher uL-FABP levels associate with worse clinical parameters and may diagnose and predict CPB-AKI earlier.

Claves:acute kidney injury, biomarkers, cardiac surgery, cardiopulmonary bypass, liver-type fatty acid-binding protein, pediatrics

Cita:Int J Mol Sci 2024 Apr 30; 25 (9)

Autor/es:Wilnes, Bruno (a)
Castello-Branco, Beatriz (b)

institución:(a) Interdisciplinary Laboratory of Medical Investigation, Unit of Pediatric Nephrology, Department of Pediatrics, Faculty of Medicine, Federal University of Minas Gerais, Belo Horizonte 30130-100, MG, Brazil.
(b) Interdisciplinary Laboratory of Medical Investigation, Unit of Pediatric Nephrology, Department of Pediatrics, Faculty of Medicine, Federal University of Minas Gerais, Belo Horizonte 30130-100, MG, Brazil.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3390/ijms25094912

Validation of Nutritional Approaches to Modulate Cardiovascular and Diabetic Risk Factors in Patients with Hypertriglyceridemia or Prediabetes-The MoKaRi II Randomized Controlled Study.

Validation of Nutritional Approaches to Modulate Cardiovascular and Diabetic Risk Factors in Patients with Hypertriglyceridemia or Prediabetes-The MoKaRi II Randomized Controlled Study.

Fuente:Nutrients

Extracto: In patients with elevated TG or fasting glucose, implementing individualized menu plans in combination with regular counseling sessions over 10 weeks led to a significant improvement in cardiovascular and diabetic risk factors.

Claves:cardiovascular risk, diabetes mellitus type 2, fish oil supplementation, hypertriglyceridemia, menu plans, prediabetes

Cita:Nutrients 2024 Apr 24; 16 (9)

Autor/es:Braun, Theresa S (a)
Drobner, Timo (b)

institución:(a) Junior Research Group Nutritional Concepts, Institute of Nutritional Sciences, Friedrich Schiller University Jena, Dornburger Straße 25-29, 07743 Jena, Germany.
(b) Competence Cluster for Nutrition and Cardiovascular Health (nutriCARD) Halle-Jena-Leipzig, Dornburger Straße 25-29, 07743 Jena, Germany.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3390/nu16091261

The Role of Diet in the Cardiovascular Health of Childhood Cancer Survivors-A Systematic Review.

Fuente:Nutrients

Tipo de trabajo:Revisión sistemática

Extracto: The review results indicate the potentially protective effects of healthy diets. However, the available research remains preliminary and limited, underscoring the need for more rigorous, adequately powered studies.

Claves:cardiac dysfunction, cardiovascular disease risk factors, cardiovascular diseases, childhood cancer survivors, diet, diet recommendations

Cita:Nutrients 2024 Apr 27; 16 (9)

Autor/es:Li, Ruijie (a)
Barker, Alan R (b)

institución:(a) Children's Health & Exercise Research Centre (CHERC), Faculty of Health and Life Sciences, University of Exeter, Exeter EX1 2LU, UK.
(b) Children's Health & Exercise Research Centre (CHERC), Faculty of Health and Life Sciences, University of Exeter, Exeter EX1 2LU, UK.

Conflicto:The authors report no conflict of interest.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3390/nu16091315

Managing Undernutrition in Pediatric Oncology

Fuente:Nutrients

Tipo de trabajo:Consenso

Extracto: This consensus statement establishes a standardized approach to nutritional support, aiming to optimize outcomes in pediatric cancer patients.

Claves:childhood cancer, nutrition, nutritional support

Cita:Nutrients 2024 Apr 28; 16 (9)

Autor/es:Budka-Chrzęszczyk, Agnieszka (a)
Szlagatys-Sidorkiewicz, Agnieszka (b)

institución:(a) Department of Pediatrics, Pediatric Gastroenterology, Allergology and Nutrition, Medical University of Gdansk, 80-210 Gdansk, Poland.
(b) Department of Pediatrics, Pediatric Gastroenterology, Allergology and Nutrition, Medical University of Gdansk, 80-210 Gdansk, Poland.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3390/nu16091327

Endovascular treatment in Danon disease

Endovascular treatment in Danon disease

Fuente:Journal of Medical Case Reports

Tipo de trabajo:Caso clínico

Extracto: To our knowledge, we report the first case of ischemic stroke related to Danon disease treated with endovascular treatment.

Claves:Cardiomyopathy, Case report, Danon, Lysosomal, Stroke

Cita:J Med Case Rep 2024 May 12; 18 (1) : 244.

Autor/es:Jiménez-Bolaños, Rayco (a)
Hernández-Fernández, Francisco (b)

institución:(a) Department of Neurology, Complejo Hospitalario Universitario Insular-Materno Infantil de Canarias, Las Palmas, Spain.
(b) Department of Neurology, Complejo Hospitalario Universitario de Albacete, C/Hermanos Falcó 37, 02006, Albacete, Spain. pacohdezfdez@hotmail.com.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s13256-024-04555-7

Pubertal Timing Across Asian American, Native Hawaiian, and Pacific Islander Subgroups.

Pubertal Timing Across Asian American, Native Hawaiian, and Pacific Islander Subgroups.

Fuente:Jama Network Open

Tipo de trabajo:Estudio de cohortes

Extracto: AND RELEVANCE: In this cohort study of Asian American, Native Hawaiian, and Pacific Islander children and adolescents, pubertal timing varied considerably across ethnic subgroups. Further investigation is warranted to assess whether these differences contribute to observed health disparities in adulthood, such as type 2 diabetes and cardiovascular diseases.

Cita:JAMA Netw Open 2024 May 1; 7 (5) : e2410253.

Autor/es:Kubo, Ai (a)
Acker, Julia (b)

institución:(a) Kaiser Permanente Division of Research, Oakland, California.
(b) School of Public Health, University of California, Berkeley.

Conflicto:Conflict of Interest Disclosures: Dr Kubo reported receiving grants from the National Institute of Mental Health, National Institutes of Health (NIH), during the conduct of the study. Ms Aghaee reported receiving grants from the NIH during the conduct of the study. Dr Kushi reported receiving grants from the NIH during the conduct of the study. Dr Quesenberry reported receiving grants... from the NIH during the conduct of the study. Dr Kanaya reported receiving grants from the NIH during the conduct of the study. Dr. Deardorff reported receiving grants from the NIH during the conduct of the study. No other disclosures were reported.

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1001/jamanetworkopen.2024.10253

Anti-Hu antibody associated paraneoplastic neurological syndrome in a child with ganglioneuroblastoma

Fuente:Medicine

Tipo de trabajo:Revisión

Extracto: Early detection of paraneoplastic neurological syndromes can help take appropriate regimens and improve prognosis.

Cita:Medicine (Baltimore) 2024 May 10; 103 (19) : e38148.

Autor/es:Dai, Yi-Ling (a)
Xiao, Ling (b)

institución:(a) Key Laboratory of Birth Defects and Related Diseases of Women and Children, Ministry of Education, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, P.R. China.
(b) Department of Pediatrics, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, P.R. China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe impreso

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1097/MD.0000000000038148

Expression and significance of procalcitonin, leukotriene B4, serum amyloid A, and C-reactive protein in children with different types of pneumonia: An observational study.

Fuente:Medicine

Extracto: Serum PCT and SAA showed diagnostic value for bacterial pneumonia, and serum SAA and CRP showed diagnostic value for viral pneumonia; serum PCT, LTB4, and SAA correlate with severity of disease and show higher expression with worsening of the condition.

Cita:Medicine (Baltimore) 2024 May 10; 103 (19) : e37817.

Autor/es:Pan, Tinghui (a)
Guo, Xiwen (b)

institución:(a) Department of Paediatrics, The Fifth People's Hospital of Zhuhai, Zhuhai, Guangdong, China.
(b) Department of Human Anatomy and Histology & Embryology, Zunyi Medical University, Zhuhai Campus, Zhuhai, Guangdong, China.

Conflicto:The authors have no funding and conflicts of interest to disclose.

Formato:Informe impreso

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1097/MD.0000000000037817

Management of pediatric liver failure with therapeutic plasma exchange and continuous renal replacement therapy: A retrospective observational study.

Fuente:Medicine

Extracto: Future multicentric studies are needed for broader validation of these findings in liver failure management.

Cita:Medicine (Baltimore) 2024 May 10; 103 (19) : e38093.

Autor/es:Colak, Mustafa (a)
Ocak, Ilhan (b)

institución:Colak, Mustafa (a)
Ocak, Ilhan (b)

Conflicto:The authors have no funding and conflict of interest to disclose.

Formato:Informe impreso

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1097/MD.0000000000038093

Streptococcus pneumoniae among the children of Aden, Yemen: a cross-sectional report of post-pneumococcal conjugate vaccine.

Fuente:Journal of Infection in Developing Countries

Extracto: A high pneumococcal carriage rate was observed in Yemeni children, particularly in low-income households and shared living conditions. There was significant penicillin resistance at meningitis breakpoint. Furthermore, non-PCV13 serotypes were gradually replacing PCV13 serotypes. The findings underscore the urgent need for enhanced surveillance and stewardship to improve vaccination and antibiotic policies in Yemen.

Claves:Yemen, antimicrobial, children, pneumococci, serotypes, vaccine

Cita:J Infect Dev Ctries 2024 Apr 30; 18 (4) : 579-586.

Autor/es:Matran, Yasser M (a)
Al-Haddad, Ahmed M (b)

institución:(a) Department of Para-Clinic, Unit of Clinical Microbiology, Faculty of Medicine and Health Sciences, University of Aden, Yemen.
(b) Department of Medical Laboratory Sciences, College of Medicine and Health Sciences, Hadhramout University, Yemen.

Conflicto:No Conflict of Interest is declared

Formato:Informe virtual

Idioma:Inglés

País de fuente:Italia

Sitio web:http://dx.doi.org/10.3855/jidc.18935

Evaluation of a walking school bus program: a cluster randomized controlled trial.

Fuente:The International Journal of Behavioral Nutrition and Physical Activity

Tipo de trabajo:Estudio aleatorizado y controlado

Extracto: These findings support implementation of walking school bus programs that are inclusive of school-age children from lower income families to support active commuting to school and improve physical activity. TRAIL REGISTRATION: This RCT is registered at clinicaltrials.gov (NCT01626807).

Claves:Physical activity, Randomized controlled trail, School, Walking school bus, Youth

Cita:Int J Behav Nutr Phys Act 2024 May 10; 21 (1) : 55.

Autor/es:Johnson, Ashleigh M (a)
Zhou, Chuan (b)

institución:(a) School of Exercise and Nutritional Sciences, San Diego State University, 5500 Campanile Drive, San Diego, CA, 92182, USA. ajohnson12@sdsu.edu.
(b) Center for Child Health, Behavior, and Development, Seattle Children's Research Institute, 1920 Terry Avenue, Seattle, WA, 98101, USA.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12966-024-01602-w

Increasing the etanercept dose in a treat-to-target approach in juvenile idiopathic arthritis: does it help to reach the target? A post-hoc analysis of the BeSt for Kids randomised clinical trial.

Fuente:Pediatric Rheumatology Online Journal

Tipo de trabajo:Estudio clínico

Extracto: Escalation to high-dose etanercept in JIA-patients who were treated to target was generally followed by meaningful clinical improvement. However, similar improvements were observed in a smaller comparison group who did not escalate to high-dose etanercept. No SAEs were seen after escalation to high-dose etanercept. The division into the high-dose and comparison groups was not randomised, which is a potential source of bias. We advocate larger, randomised studies of high versus regular dose etanercept to provide high level evidence on efficacy and safety. TRIAL REGISTRATION: Dutch Trial Register; NTR1574; 3 December 2008; https://onderzoekmetmensen.nl/en/trial/26585 .

Claves:Adverse events, Dose, Efficacy, Etanercept, Juvenile idiopathic arthritis, Randomised clinical trial, Treat-to-target

Cita:Pediatr Rheumatol Online J 2024 May 10; 22 (1) : 53.

Autor/es:van Dijk, Bastiaan T (a)
Bergstra, Sytske Anne (b)

institución:(a) Department of Paediatrics - division of Paediatric Rheumatology, Willem-Alexander Children's Hospital, Leiden University Medical Centre, Leiden, the Netherlands. B.T.van_Dijk@lumc.nl.
(b) Department of Rheumatology, Leiden University Medical Centre, Leiden, the Netherlands. B.T.van_Dijk@lumc.nl.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12969-024-00989-x